|
Match
|
Document |
Document Title |
|
|
7598066 |
Gene encoding vitamin b6 phosphate phosphatase and use thereof
Disclosed is an isolated DNA encoding vitamin B 6 phosphate phosphatase selected from the group consisting of: (a) a DNA sequence represented in SEQ ID NO:9; (b) a DNA sequence which encodes a...
|
|
|
7432089 |
DNA encoding favin-adenine-dinucleotide-dependent-D-erythronate-4-phosphate-de-hydrogenase, pdxR, and microbial production of vitamin B6
The present invention relates to a DNA encoding a novel flavin adenine dinucleotide (FAD)-dependent D-erythronate 4-phosphate (EN4P) dehydrogenase originated from Sinorhizobium meliloti , which is...
|
|
|
7371547 |
Process for producing vitamin B6
Disclosed is a mutant of a recombinant microorganism of the genus Sinorhizobium capable of producing vitamin B 6 having a recombinant plasmid with pdxJ gene that acquired histidine requirement...
|
|
|
7297800 |
Process of producing glutamate derivatives
The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into...
|
|
|
7241601 |
Process for the preparation of Fexofenadine
A process for the preparation of a compound of the formula
by means of bioconversion with a microorganism culture of a compound of the formula
|
|
|
7232908 |
Process for the production of piperidine derivatives with microorganisms
The present invention relates to a process for the production of piperidine derivatives with microorganisms. This is carried out by incubating starting compounds in the presence of a microorganism...
|
|
|
7052885 |
Process for preparing heterocyclic (R)- and (S)-cyanohydrins
A process for preparing enantiomer-enriched heterocyclic (R)- and (S)-cyanohydrins of the formula (I),
where R1, R2, R3, R4 independently of one another are H, an unsubstituted or substituted C...
|
|
|
6946269 |
Alkyl esters of 3-(3,4-dihalophenyl)-2,6-dioxopiperidine-3-propionic acid of use as intermediates
The invention relates to lower-alkyl esters of 3-(3,4-dihalophenyl)-2,6-dioxopiperidine-3-propionic acid derivatives, and to processes for preparing the same.
|
|
|
6919199 |
Microbes and methods for remediation
The present invention provides methods of using a microbe containing a polypeptide that degrades, preferably detoxifies, a compound that is present in the environment. Preferably, the polypeptide...
|
|
|
6780635 |
Process for the preparation of optically active azabicyclo heptanone derivatives
The present invention provides a process for preparation of optically active azabicyclo heptanone derivates using lactamases that will react with racemic lactam of formula (I) to give a single...
|
|
|
6780634 |
Method for producing (1R,4S)-2-azabicyclo&lsqb 2.2.1&rsqb -hept-5-en-3-on derivatives
A biotechnological method is described for preparing compounds of the general formulas wherein R 1 is acyl or acyloxy and R 2 is a hydrogen atom or C 1-10 alkyl, comprising the conversion of...
|
|
|
6770463 |
Process for the preparation of chiral isofluoroenes
There is provided a process for the preparation of a chiral insecticidal and acaricidal compound of formula I. Also provided are intermediate compounds useful in the process of the present...
|
|
|
6689587 |
Polynucleotides encoding the nadC gene and methods of producing nicotinic acid or nicotinic acid derivatives
The present invention relates to polynucleotides corresponding to the nadC gene and which encode the nicotinate nucleotide pyrophosphorylase protein, methods of producing nicotinic acid or...
|
|
|
6489147 |
Gene for adenylate cyclase and its use
A gene which contains the nucleotide sequence shown in SEQ ID NO:1 from nucleotide 671 to nucleotide 6295 or a nucleotide sequence which can be obtained therefrom by substitution, insertion or...
|
|
|
6451587 |
Microbial asymmetric reduction of 2-chloro-1-&lsqb -6-(2,5-dimethyl-pyrrol-1-yl)-pyridin-3-yl&rsqb -ethanone
The present invention relates to microbial processes for carrying out the asymmetric reduction of a ketone to an alcohol, which comprises: contacting the ketone with a microorganism, or an enzyme...
|
|
|
6444450 |
Large-scale production of polyphenols or polyaromatic amines using enzyme-mediated reactions
A process for large-scale, low cost, batch or continuous production of polyphenols using enzyme-mediated reactions and methods for recycling non-consumed reactants.
|
|
|
6416979 |
5-substituted picolinic acid compounds production by Marasmiellus sp
The present invention provides novel 5-substituted picolinic acid compounds of formula (I) or a pharmaceutically acceptable salt thereof: wherein R 1 and R 2 are independently H, C 2 -C 6 ...
|
|
|
6410265 |
Gene encoding a putive efflux protein for solvents/antibiotics in Pseudomonas mendocina
This invention relates to the isolation of a novel putative efflux gene from Pseudomonas mendocina . The putative efflux gene is useful for probing an organism's efflux system to gain an...
|
|
|
6406912 |
Method for enzymatic enantiomer-separation of 3(r)- and 3(s)-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydro-pyridine or its carboxylic acid esters
The invention relates to a method for producing optically pure compounds of 3(R)- and 3(S)-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tet
rahydro-pyridine or its carboxylic acid esters by...
|
|
|
6361979 |
Microbial conversion of 2-methylquinoxaline
The present invention relates to processes for the microbial oxidation of 2-methylquinoxaline to 2-quinoxalinecarboxylic acid which comprise contacting 2-methylquinoxaline with a microorganism, or...
|
|
|
6284522 |
Isolated and purified DNA molecule and protein for the degradation of triazine compounds
An isolated and purified DNA molecule, and an isolated and purified protein, that are involved in the degradation of s-triazine compounds (e.g., atrazine) are provided. A method for the...
|
|
|
6268183 |
Method of purifying thuringiensin
The invention discloses a two-step process for recovery of thuringiensin, comprising adsorbing the thuringiensin from fermentation broth by calcium silicate, and dissociating the thuringiensin by...
|
|
|
6248571 |
Method of producing dihydroxypyrimidine derivatives
A process for the preparation of dihydroxypyrimidine derivatives of the general formula: ##STR1## in which R 1 and R 2 are identical or different and are a hydrogen atom, aryl group, or a C 1 -C...
|
|
|
6207444 |
Enzymatic process of making alpha 1a adrenergic receptor antagonists using protease
This invention relates to crystalline pharmaceutically acceptable salts of an alpha 1a adrenergic receptor antagonist, Compound A, which are useful in the treatment of benign prostatic hyperplasia....
|
|
|
6143541 |
Gene encoding a protein having symmetric hydrolase activity for 4-substituted 1,4-dihydropyridine derivatives and its expression product
This invention provides DNA fragments for efficiently preparing a protein having asymmetric hydrolase activity for 4-substituted 1,4-dihydropyridine derivatives, transformants obtained by using...
|
|
|
6121025 |
Process for producing optically active 3-quinuclidinol derivatives
The present invention relates to a process for producing optically active 3-quinuclidinol or derivatives, wherein a racemic 3-quinuclidinol ester represented by the general formula (I): ##STR1##...
|
|
|
6037166 |
Enzymatic kinetic resolution of an intermediate useful for preparing substituted tricyclics
The invention relates to a process for preparing a substituted (6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)pi
peridine compound of the formula (+)-I ##STR1## wherein: R, R 1 , R 2 , R...
|
|
|
5989876 |
Colorant precursors derivable from cells of plants of the genus medicago, process for their preparation and use thereof for the preparation of colorants
Colorant precursors, which are present in the cells of plants belonging to the genus Medicago, such as alfalfa, can react with quinones so as to yield colorants which can be used in dyeing...
|
|
|
5986095 |
Enantioselective preparation of halophenyl alcohols and acylates
A process is described for preparing a compound of the formula or the S-enantiomer thereof, wherein: R is alkyl, aryl, cycloalkyl, aralkyl, or cycloalkylalkyl, R 1 is halogen; R 2 is...
|
|
|
5976563 |
Pesticidal composition and Bacillus thuringiensis strain
The invention is related to a novel strain(s) of Bacillus thuringiensis in which essentially all of the pesticidal activity of said strain is in the supernatant of a fermentation of said strain....
|
|
|
5968788 |
Method for producing folic acid
Disclosed is a method for producing folic acid, comprising incubating yeast having the ability to produce folic acid of 0.3 mg or more or incubating bacteria having the ability to produce folic...
|
|
|
5846791 |
N-(R)-(2-hydroxy-2-pyridine-3-yl-ethyl)-2-(4-nitro-phenyl)-acetamide
Asymmetric bioreduction of a ketone substrate with yeast produces the corresponding (R)-alcohol of structure: ##STR1## a key intermediate in the synthesis of a β 3 -agonist of structure ##STR2##
|
|
|
5792871 |
Process for N-Boc-N-(R)-2(3-pyridyl)-2-hydroxy-ethyl)-N-2(4-aminophenyl)ethyl amine and 2-(4-aminophenyl)-N-2-(2(R)-hydroxy-2-phyridin-S-yl-ethyl)acetamide
Compound 9 is prepared by a 9-step ##STR1## process in an overall yield of about 35% from 3-acetylpyridine. Compound 10 is prepared by a seven-step ##STR2## process in an overall yield of about 30%...
|
|
|
5776765 |
Method for preparing a pharmaceutically active enantiomeric or enantiomerically enriched sulfoxide compound by enantioselective bioreduction of a racemate sulfoxide compound
A compound of formula (II), either as a single enantiomer or in an enantiomerically enriched form ##STR1## wherein: ##STR2## and ##STR3## (wherein N in the benzimidazole moiety of Het 2 means that...
|
|
|
5766894 |
Production of vitamin B.sub.6 by fermentation
A process for producting vitamin B 6 comprises cultivating a microorganism belonging to the genus Rhizobium and being capable of producing vitamin B 6 in a culture medium under aerobic...
|
|
|
5766893 |
Biotechnological process for the preparation of cyclic s-alpha-imino carboxylic acids and r-alpha-imino carboxamides
Microorganisms of interest are capable of utilizing α-imino carboxamides, in the form of the racemate or of its optically active isomers, of the general formula ##STR1## wherein A together with...
|
|
|
5763232 |
Method for producing 3-hydroxy nitrogen-containing six-membered cylic compound
A method for producing a 3-hydroxy nitrogen-containing six-membered cyclic compound is provided. Namely, microbial cells of a microorganism and/or a preparation obtained from the microbial cells is...
|
|
|
5760238 |
1,4-dihydropyridine derivatives
Disclosed are 1,4-dihydropyridine derivatives represented by the general formula (I) and salts thereof, as well as optical active 1,4-dihydropyridine derivatives represented by the general formula...
|
|
|
5753471 |
Biotechnological perparation of alcohols, aldehydes and carboxylic acids
A process for the biotechnological preparation of alcohols, aldehydes and carboxylic acids by oxidation of compounds of the formula R 1 --C(CH 3 )CR 2 R 3 , where R 1 , R 2 and R 3 have the...
|
|
|
5733756 |
Lactams and processes for stereoselective enrichment of lactams, amides, and esters
Novel lactams and processes for the preparation of chiral compounds having utility as intermediates in the synthesis of compounds with Central Nervous System stimulant activity.
|
|
|
5733755 |
Method for the enantioselective synthesis of chiral derivatives of S-3-(4'- t
A method for manufacturing S-3-(4'-tert-butyl)-phenyl-2-methyl propylamines having the structure I ##STR1## where NR 1 R 2 is a dialkylamine group, pyrrolidine, piperidine, or cis-3,5-dimethyl...
|
|
|
5733754 |
Enzyme and its use in preparing (S)-pipecolic acid
An enzyme is provided which has acylase activity capable of hydrolyzing N-acetyl-(R,S)-pipecolic acid stereoselectively to give (S)-pipecolic acid, wherein this activity is greater than that on...
|
|
|
5719045 |
Process for preparing nicotinamide
A process for preparing nicotinamide, wherein, in the first stage, 2-methyl-1,5-diaminopentane is catalytically converted into 3-picoline, then the 3-picoline is converted via an ammonoxidation...
|
|
|
5702930 |
Microbiological process for the preparation of heteroaromatic carboxylic acids using Alcaligenes faecalis
A microbiological process for the preparation of a heteroaromatic carboxylic acid or one of its physiologically tolerated salts of the formulae I or II: ##STR1## wherein R 1 and R 2 are identical...
|
|
|
5688954 |
Process for the preparation of substituted thiopyran-1-oxides
A process is described for the preparation of a compound of formula (IX) from 4-hydroxybutyl 3-pyridyl ketone. The compound of formula (IX) is an intermediate useful in the preparation of...
|
|
|
5661014 |
Chiral compounds and their resolution synthesis using enantioselective esterases
Enantiomeric glutarimides such as aminoglutethimide and rogletimide are prepared by cyclisation of a corresponding ester-nitrile which is a good substrate for biotransformation with an...
|
|
|
5635395 |
Optically active 1,4-dihydropyridine compounds and the microbial process for the stereoselection thereof
(4R)-3-(Substituted aminoalkyl)oxycarbonyl-1,4-dihydro-2,6-dimethyl-4-(nitrophen
yl)pyridine-5- carboxylic acids can be prepared efficiently, by reacting bis(substituted aminoalkyl)...
|
|
|
5593871 |
Process for the preparation of enantiometric 2-alkanoic acid amides from nitriles
This invention relates to the enantioselective biologically-catalyzed hydrolysis of certain racemic nitriles to the corresponding R- or S-amides, chemically or biologically-catalyzed hydrolysis of...
|
|
|
5571685 |
Morphinone reductase for the preparation of hydromorphone and hydrocodone
A morphinone reductase enzyme and related process provide for the preparation of hydromorphone from morphinone and hydrocodone from neopinone or codeinone. The enzyme has no significant activity...
|
|
|
5565585 |
Azido diacetal propane derivatives
A new and practical method for synthesizing heterocyclic polyhydroxylated alkaloids using enzymatic aldol condensation and catalytic intramolecular reductive amination is disclosed.
|