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4859592 |
Production of picolinic acid and pyridine products via pseudomonas
This invention provides a process for the bioconversion of a non-growth aromatic feed to an accumulated quantity of a picolinic acid product with reduced accumulation of 2-hydroxymuconic...
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4837150 |
Oxidation processes
A process in which a culture of a methane-oxidizing bacterium or an extract thereof containing a methane oxidizing system is used as oxidizing agent for the oxidation of a higher short-chain...
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4783402 |
Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique
A process for producing a primary or secondary alcohol derivative of a phosopholipid which comprises reacting the phospholipid with a primary or secondary alcohol in the presence of phospholipase DM.
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4782019 |
Enzymatic production of sphingophospholipid derivatives
A process for producing a sphingophospholipid derivative comprising reacting a sphingophospholipid with a specified compound having an alcoholic hydroxyl group selected from the group consisting of...
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4738924 |
Method for the production of 6-hydroxynicotinic acid
Process for the production of 6-hydroxynicotinic acid by biotechnological methods. Nicotinic acid is enzymatically hydroxylated in the presence of equivalent quantities of magnesium or barium ions...
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4738929 |
Purified culture of streptomyces galanosa
Acids, esters, imine acids, imine esters, and imine amides derived from 6-formyl-4,7,9-trihydroxy-1-phenazinecarboxylic acid, methyl ester and from...
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4717664 |
Method for producing secondary metabolites of plants
This invention provides for a method for producing secondary metabolites of higher plants, such as Lithospermum erythrorhizon, Coptis japonica, and Nicotinia tabacum, by suspension cultures of a...
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4613666 |
Neplanocin A derivatives
Neplanocin A derivatives of the formula ##STR1## wherein R 1 and R 2 are hydrogen or benzoyl, R 3 is hydrogen or OR 8 , R 5 is hydrogen or acetyl, R 6 is hydrogen, acetyl or benzoyl, when R 3 ...
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4594324 |
Microbiological process for oxidizing organic compounds
A process in which a culture of a methane-oxidizing bacterium or an extract thereof containing a methane oxidizing system is used as oxidizing agent for the oxidation of a higher short-chain...
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4593097 |
Phenazine carboxylic acid derivatives and a process for production thereof
Phenazine compounds represented by the formula: ##STR1## wherein R is a hydrogen atom, an unsubstituted or substituted lower alkanoyl group, or an unsubstituted or substituted arylcarbonyl group...
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4581360 |
Sparsomycin (S.sub.c -R.sub.s) derivative; pharmaceutical composition having anti-tumor activity
The invention concerns novel sparsomycin (S c -R s ) derivatives having superior cytostatic activity compared to sparsomycin itself. Said derivatives contain a lipophilic group R 2 , selected from...
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4568641 |
Process for producing optically active aryloxypropionic acids and derivatives thereof
A process for the stereospecific inversion of the [S] enantiomer of an α-aryloxypropionic acid of formula I: ##STR1## wherein G is OR 1 or ##STR2## R 1 is hydrogen or a protecting group and R 2 ...
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4415658 |
Process for decomposing 2,4-dihydroxy-6-amino-s-triazine derivatives
The invention relates to a process for decomposing 2,4-dihydroxy-6-amino-s-triazine derivatives in effluents. The essential feature of the process is that the effluent is brought into contact under...
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4404281 |
Process for enzyme inhibitors
Angiotensin I converting enzyme inhibitor A-58365 factor A is produced in enhanced yields by culturing Streptomyces chromofuscus NRRL 15098 under submerged aerobic fermentation conditions in a...
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4404282 |
Process for enzyme inhibitor
Angiotensin I converting enzyme inhibitor A-58365 factor B is provided in greater abundance than coproduced Factor A by culturing Streptomyces chromofuscus NRRL 15098 under submerged aerobic...
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4339585 |
Method for the production of 2-hydroxymethyl-3,4,5-trihydroxy piperidine and the corresponding N-methyl derivative
Moranoline, or 2-hydroxymethyl-3,4,5-trihydroxy piperidine, is prepared by directly reducing an actinomycetes culture solution containing nojirimycin, followed by isolation, as for example, through...
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4321376 |
Neplanocin-B and -F
Neplanocin-B and -F of the formula ##STR1## in which Y is oxygen or a valence bond, are produced by culturing Ampullariella sp. A 11079 FERM-P No. 4494 in a nutrient medium and then separating the...
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4316959 |
Process for production of antibiotic from streptomyces
Antibiotic A-32256 which is produced by submerged, aerobic fermentation of a Streptomyces sp. NRRL 12067. The antibiotic has shown antibacterial activity against Staphylococcus and Streptococcus...
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4307194 |
Inhibitors, obtained from bacilli, for glycoside hydrolases
According to the present invention inhibitors for glycoside hydrolases, and in particular glucosidase inhibitors especially saccharase inhibitors, which are active in the digestive tract are formed...
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4274955 |
Process for the degradation of cyanuric acid
The invention relates to a microbial process for the degradation of cyanuric acid in waste water containing cyanuric acid. The essential feature of the process is that a fungus of the Sporothrix...
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4266025 |
Production of N-substituted derivatives of 1-desoxy-nojirimycin
The invention relates to a process for the production of compounds of the formula ##STR1## in which R is hydrogen or optionally substituted alkyl, alkenyl, aralkyl or aryl, by microbiological...
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4241536 |
Embryogenesis in vitro, induction of qualitative and quantitative changes in metabolites produced by plants and products thereof
The process of embryogenesis in vitro whereby single embryonic cells are obtained and from which normal, healthy plants can be produced. The process is capable of making, in vitro, any metabolite...
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4225674 |
Process for producing new ansamycin antibiotic
A new subspecies of Streptomyces nigellus Prokop, designated Streptomyces nigellus Prokop subsp. africanus Huang subsp. nov. ATCC 31496, when propagated under aerobic conditions in aqueous nutrient...
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4198481 |
Process for the preparation of 2-hydroxymethyl-3,4,5-trihydroxy piperidine
2-Hydroxymethyl-3,4,5-trihydroxy piperidine, or moranoline, is prepared by culturing a moranoline-producing strain of microorganism of the genus Streptomyces in an appropriate culture medium and...
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4019959 |
Bacterial production of lipase and pyocyanine from n-paraffins
A method of producing lipase and pyocyanine from n-paraffins by growing a pseudomonas-like hydrocarbon oxidizing bacteria thereon and extracting the lipase and pyocyanine from the intracellular...
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4010075 |
Process for producing 4-thiouracil
A novel microbiological process for preparing 4-thiouracil, a known and useful compound. The compound is produced by the controlled fermentation of the new microorganism Streptomyces libani subsp....
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4009077 |
Process for the preparation of phenopicolinic acid
Phenopicolinic acid is produced by culturing a strain of Paecilomyces. The compound, which may be alternatively named as 5-(4-hydroxybenzyl)-2-pyridinecarboxylic acid, is a hypotensive agent.
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3998698 |
Process for producing antibiotic U-51,640
Antibiotic U-51,640 produced by the controlled fermentation of the microorganism Streptomyces ficellus Dietz, sp. n., NRRL 8067. This antibiotic and its acid addition salts are active against...
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3940393 |
Synthesis of 2,6-diaminopyrimidines
New, substituted, 2,6-diaminopyrimidines are disclosed. These compounds are useful as anti-malarial agents. The oxygenation of pyrimethamine by fungi is also disclosed.
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3926731 |
3-(5,7-Dimethyl-2-hydroxy-4-oxo-6,8-decadienyl)-glutarimide fermentation
3-(5,7-Dimethyl-2-hydroxy-4-oxo-6,8-decadienyl)-glutarimide is prepared by cultivating Streptomyces pluricolorescens var. yamashitaensis (S-855) ATCC No. 21956 in an aqueous nutrient broth...
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3919047 |
Microbiological hydroxylation of 2,6-methano-3-benzazocines
2,6-Methano-3-benzazocines of the formula ##SPC1## Wherein Q' is a benzoyl group, R 1 and R 2 each are a hydrogen atom or lower alkyl and Z' is a free, etherified or esterified hydroxy group, are...
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3917703 |
4-(Aminoalkylamino)-2-halobenzyl lower-alkyl ethers
4-[Amino-(polycarbon-lower-alkyl)-amino]-2-halobenzyl alcohols and lower-alkyl ethers thereof have schistosomacidal activity. The benzyl alcohols are prepared: by reduction of the corresponding...
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3915803 |
Process for producing cycloheximide
It has been found that cycloheximide production by a culture of Streptomyces griseus is maintained and total yields of the antibiotic are increased when a glucose feed is begun at about 48 hrs. and...
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3915802 |
Dialysis process and apparatus
A new dialysis method and apparatus is described for separating, accumulating, and recovering cycloheximide from a culture medium wherein Streptomyces griseus is producing the antibiotic. The new...
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3887433 |
Process for production of antibiotic A-25822
Antibiotic mixture A-25822, comprising microbiologically active, structurally related factors A, B, D, H, L, M and N, produced by culturing Geotrichum flavo-brunneum NRRL 3862 under submerged...
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3887564 |
Antibiotic A-25822 and process for production therof
Antibiotic mixture A-25822, comprising microbiologically active, structurally related factors A, B, D, H, L, M and N, produced by culturing Geotrichum flavo-brunneum NRRL 3862 under submerged...
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3880858 |
3-(5,7-DIMETHYL-2-HYDROXY-4-OXO-6,8-DECADIENYL)-GLUTARIMIDE
3-(5,7-Dimethyl-2-hydroxy-4-oxo-6,8-decadienyl)-glutarimide is prepared by cultivating Streptomyces pluricolorescens var. yamashitaensis (S-885) ATCC No. 21956 in an aqueous nutrient broth...
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3852424 |
PURIFIED FERRIMYCIN AND PROCESS FOR OBTAINING SAME
The antibiotic ferrimycin A, its components ferrimycin A 1 and ferrimycin A 2 and the corresponding iron-free compounds desferrimycin A, desferrimycin A 1 and desferrimycin A 2 , and also...
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3844889 |
PROCESS OF PREPARING 2-HYDROXY-2-CARBOXYLTHYL-N(7-OR 8-CHLORO-4-QUINOLINYL)ANTHRANILATE
A process of preparing 2-Hydroxy-2-carboxyethyl-N-(7- or 8-chloro-4-quinolinyl)anthranilate by microbial transformation of 2,3-dihydroxypropyl-N-(7- or 8-chloro-4-quinolinyl)anthranilate by...
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3839152 |
PREPARATION OF NOVEL DERIVATIVES OF 2,3 DIHYDROXYPROPYL-N-(7 OR 8 CHLORO-4 QUINOLINYL)ANTHRANILATE
A process of preparing novel derivatives of 2,3-dihydroxypropyl-N-(7 or 8-chloro-4-quinolinyl)anthranilate. The compounds are represented by the formula ##SPC1## Wherein the chloro is in the 7- or...
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3663373 |
PROCESS FOR THE PREPARATION OF IODININ
A method for producing iodinin through the cultivation of selected isolates of the organism Brevibacterium iodinum. Cultivation takes place in a specialized nutrient medium and the iodinin is...
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3622457 |
PROCESS FOR PREPARING 5-(AMINOALKYLAMINO)-6 (OR 7)-HALO-8-QUINOLINE METHANOLS
5-(aminoalkylamino)-6(or 7)-halo-8-quinolinemethanols, having schistosomacidal activity, are prepared by subjecting the correspoonding 6(or 7)-halo-5-(aminoalkylamino)-8-methylquinoline to the...
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3616228 |
β-SUBSTITUTED PROPIONIC ACIDS AND METHOD OF MAKING THE SAME
A β-substituted propionic acid of the general formula ##SPC1## Wherein W is CH 2 , O or NH and wherein X and Y may be the same or different and are H, OH, =O, OAc, lower alkyl, hydroxy- or oxo-...
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3379620 |
Process for producing 4-aminobenzyl alcohol derivatives
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3359165 |
Antibiotic lomondomycin and method of production
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3297526 |
Process for producing coprogen and desferricoprogen
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3214431 |
Novel glutarimides
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3153621 |
Process for producing ferrioxamines
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3137626 |
Plant antiviral compositions and methods for preparing the same
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3093550 |
Process for the manufacture of ferrimycin
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