Matches 51 - 100 out of 171 < 1 2 3 4 >
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5563053 Process for production of amide compounds using microorganism  
The present invention provides a process for production of amide compounds, which includes converting a nitrile compound into its corresponding amide compound by hydrating the nitrile compound in...
5559017 Microbial reduction of benzazepines and benzothiazepine derivatives  
A novel process comprises reducing a benzazepine or benzothiazepine at the 3-position in d-cis configuration by treatment with reductase-supplying microorganisms or enzymes derived therefrom. The...
5539111 Process for resolution of racemates of 4-aryl-2-oxo-pyrrolidine-3-carboxylic acid esters  
An enzymatic process employing pancreatin or choelsterol esterase for resolution of racemates of 4-aryl-2-oxo-pyrrolidine-3-carboxylic acid esters of general formula I ##STR1## in which X...
5532149 Removal of phthalyl groups from amides and esters using an amidase isolated from Xanthobacter Agilis  
Phthalyl amidase is an enzyme previously unknown in the art that catalyzes removal of the phthalyl moiety from phthalyl-containing amides. The current invention provides a phthalyl amidase, a...
5516661 Microbiological process for the production of aromatic hydroxy-heterocyclic carboxylic acids  
The microbiological process for the production of hydroxy-heterocyclic carboxylic acid of formula ##STR1## wherein R 1 means a hydrogen or a halogen atom and X means a nitrogen atom or a CR 2 ...
5494816 Enhanced indole biosynthesis  
DNA molecules encoding a modified tryptophan synthase beta subunit are disclosed. When expressed in a recombinant host microorganism, these polypeptide analogs enable significant levels of...
5491077 Microbial method  
The present invention provides a process for the stereoselective reduction of phenylalkyl ketones to their corresponding (S)-hydroxy compounds. The process utilizes the novel microorganism...
5436145 Process for preparing 6-hydroxy nitrogen-containing 6-membered ring compounds  
6-Hydroxy nitrogen-containing 6-membered ring compounds of the following general formula (II): ##STR1## wherein R 1 represents carboxy group, carbamoyl group, cyano group, formyl group, C 1 -C 5 ...
5427933 Reduction of phenylalkyl ketones to the corresponding (S)-hydroxy derivatives using mucor hiemalis IFO 5834  
A process for reducing a phenylalkyl ketone to the corresponding (S)-hydroxy derivative is disclosed. The process comprises contacting the phenylalkyl ketone with Mucor hiemalis IFO 5834 and...
5395758 Process for production of amide compounds using agrobacterium radiobacter  
There is disclosed a process for production of amide compounds which includes converting a nitrile compound into an amide compound using a cultured broth of bacterial cells, or bacterial cells or...
5393663 Stereoselective preparation of halophenyl alcohols from ketones  
A process is described for selectively preparing a compound of the formula ##STR1## wherein: R 1 is halogen; R 2 is halogen, alkyl, cycloalkyl, aryl or ##STR2## and R 3 hydrogen, alkyl,...
5364776 Method of hydroxylating 3-[3-(5-ethyl-2-methoxy-6-methylpyridyl)methyl]amino-5-ethyl-6-methyl-2( 1H)-pyridinone with liver slices  
Incubation of ##STR1## with a preparation from mammalian organ yields as biotransformation products the 5-(1-hydroxy)ethyl pyridinone analog as well as the 5-(1-hydroxy)ethyl pyridyl and the...
5364940 Microbiological process for hydroxylation of nitrogen-heterocyclic-carboxylic acids  
A new microbiological process for the production of hydroxy-nitrogen-heterocyclic-carboxylic acids or their soluble salts of the general formula: ##STR1## wherein R 1 and R 2 are the same or...
5352592 Microbiological process for the production of 5-hydroxypyrazinecarboxylic acid  
A microbiological process for the production of 5-hydroxypyrazinecarboxylic acid and/or its salts with microorganisms of the strain Agrobacterium sp. DSM 6336 or descendants thereof or mutants...
5342767 Lactobacillus kefir alcohol dehydrogenase  
The present invention discloses the preparation of R-configured trialkylsilylethynyl α-alcohols from similarly substituted α-ketones, and vice versa, catalyzed by the alcohol dehydrogenase of...
5334517 Microbial process for the production of trans-4-hydroxy-L-proline  
Trans-4-hydroxy-L-proline is produced microbially, especially by the cultivation of a microorganism of the genus Clonostachys, Gliocladium or Nectria.
5320955 10'desmethoxystreptonigrin production by Streptomyces albus  
10'-Desmethoxystreptonigrin, obtainable by cultivation of a strain of Streptomyces albus, A.T.C.C. No. 55161, and salts, esters and amides thereof. The novel compounds have antitumor and antibiotic...
5310741 TAN-1251 compounds and their production from penicillium thomii  
A compound of the formula ##STR1## wherein R 1 is hydrogen or a hydrocarbon residue which may be substituted; R 2 is oxo or hydrogen plus hydroxy which may be acylated; R 3 is hydrogen or...
5306625 Process for terminal hydroxylation of ethyl groups on aromatic 5- or 6-ring heterocycles  
A microbiological process for terminal hydroxylation of ethyl groups on aromatic 5- or 6-member ring heterocycles. The hydroxylation is performed with microorganisms which: (a) contain the genes...
5298414 Detection of morphine using morphine dehydrogenase  
Two enzymes, one an acetylmorphine carboxyesterase (AMCE), the other a morphine dehydrogenase (MDH), have been isolated from bacteria. The AMCE degrades heroin to morphine and the MDH oxidises...
5284767 Microorganisms useful for the production of hydroxylated heterocycles  
Microorganisms which are capable of growing with 2,5-dimethylpyrazine as the sole carbon, nitrogen and energy source. These microorganisms hydroxylate heterocycles of general formula: ##STR1## to...
5275950 Process for the preparation of a renin inhibiting compound  
Intermediates and a process for their preparation are disclosed which are useful for the preparation of a renin inhibiting compound of the formula: ##STR1## wherein R is a nitrogen-containing...
5273893 Microbiological process for the production of hydroxypyrazinecarboxylic acid  
A microbiological process for the production of 5-hydroxypyrazinecarboxylic acid and/or its salts with microorganisms using nicotinic acid and/or its salts.
5268294 Alcaligenes faecalis strains useful for the microbiological process for the production of 6-hydroxypicolinic acid  
A microbiological process for the production of 6-hydroxypicolinic acid starting from picolinic acid and/or its salts. The concentration of picolinic acid and/or its salts is selected so that the...
5266469 Microbiological process for the production of 6-hydroxynicotinic acid  
A microbiological process for the production of 6-hydroxynicotinic acid starting from 3-cyanopyridine. For this process, new microorganisms are used, which are capable of growing with...
5266482 Agrobacterium useful for the microbiological process for the production of hydroxylated pyrazine derivatives  
Microorganisms, which are capable of growing with pyrazine as the sole carbon, nitrogen and energy source. These microorganisms hydroxylate pyrazine derivatives of general formula: ##STR1## to...
5242816 Microbiological oxidation of alkyl groups in heterocycles  
A microbiological process for the terminal oxidation of alkyl groups in 5- or 6-ring heterocycles which are substituted with at least one alkyl group with more than 2 carbon atoms to carboxylic...
5238829 Microbiological process for the production of 6-hydroxypyrazinecarboxylic acid  
A microbiological process for the production of 6-hydroxypyrazinecarboxylic acid and/or its salts with microorganisms using picolinic acid and/or its salts. The microorganisms grow with picolinic...
5236832 Microbiological oxidation of methyl groups in heterocycles  
A microbiological process for the oxidation of methyl groups in aromatic 5- or 6-member ring heterocycles to the corresponding carboxylic acid. The heterocycle serves as the substrate and exhibits...
5229278 Microbiological process for the production of hydroxylated heterocycles  
Microorganisms which are capable of growing with 2,5-dimethylpyrazine as the sole carbon, nitrogen and energy source. These microorganisms hydroxylate heterocycles of general formula: ##STR1## to...
5219754 Strain Ophiobolus vermisporus FERM BP-1636  
This disclosure describes a novel antibiotic designated Vermisporin produced in a microbiological fermentation using, for example, a new strain of Ophiobolus Vermisporus L-8. This novel antibiotic...
5217884 Hydroxylation of methyl groups in aromatic heterocycles by microorganisms  
A process using microorganisms which contain genes, which form an active xylene monooxygenase, which form no effective, chromosomally or plasmid-coded alcohol hydrogenase, and which are, thus,...
5213973 Microbiological process for oxidation of methyl groups  
A microbiological process for oxidation of methyl groups in aromatic 5- or 6-ring heterocycles to the corresponding carboxylic acid. The reaction of the heterocycle takes place by microorganisms of...
5204249 Process for the preparation of carebastine and similar materials  
The invention relates to a novel process for the preparation of carebastine and similar materials from ebastine or terfenadine by oxidization using microorganisms. Carebastine and similar materials...
5173412 Microbiological process for the production of hydroxylated pyrazine derivatives  
Microorganisms, which are capable of growing with pyrazine as the sole carbon, nitrogen and energy source. These microorganisms hydroxylate pyrazine derivatives of general formula: ##STR1## to...
5166060 Process for the preparation of pyridine-2,3-dicarboxylic acids  
Pyridine-2,3-dicarboxylic acids are prepared by the action of 2,3-dihydroxybenzoate-3,4-dioxygenase on 2,3-dihydroxybenzoic acids in a liquid medium which lacks active decarboxylase and which has a...
5151351 Process for the production of 6-hydroxynicotinic acid  
A process for the production of 6-hydroxynicotinic acid from nicotinic acid by means of enzymatic hydroxylation in the presence of microorganisms of the genera Pseudomonas, Bacillus or...
5135858 Process for biological production of organic acids  
An improved biological conversion of a nitrile such as acrylonitrile or a cyanopyridine into the corresponding carboxylic acid such as acrylic acid or a nicotinic acid by the action upon the...
5130252 Resolution of furopyridine enantiomers and synthetic precursors thereof  
A method for resolving racemic mixtures of compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof that includes the steps of reacting the OR 3 group of either compound...
5122461 Preparation of pyrocatecholic compounds  
The invention relates to a novel method for preparing pyrocatecholic compounds from monophenolic compounds using catalysis by monophenol monooxygenase in an aqueous solution containing metal ions....
5098836 Deoxygenation in field preparation of polymers in aqueous solution  
In a process for polymerizing monomers with free-radical initiators in aqueous solution to produce polymers useful in oil field applications, wherein said polymerization process employs an...
5093247 Phenanthridine derivatives, process for the preparation thereof, and compositions containing them  
The invention relates to 1,8-dihydroxy-3-methylbenz[b]phenanthridine-7,12-dione and its derivatives of formula I ##STR1## wherein R 1 is hydrogen or the radical of formula II ##STR2## and salts of...
5082777 Process for the production of 6-hydroxynicotinic acid  
Process for the production of 6-hydroxynicotinic acid from nicotinic acid. The hydroxylation is carried out enzymatically in the presence of a microorganism of the species Pseudomonas, Bacillus or...
5070022 Enzymic process for preparing leukotriene antagonists  
Disclosed is a process for preparing the R and S enantiomers of a compound of the formula; ##STR1## which comprises; (1) reacting an enzyme with a prochiral diester of the formula ##STR2## where M...
5053338 Kinetic resolution of pyridazinones using lipase  
A kinetic resolution of pyridazinones of the following formula (A): ##STR1## where R 1 is alkyl by enzymatic hydrolysis results in good optical purity of the phenolic product. This is significant...
5026642 Process for the enzymatic production of ketones  
In a process for the reduction of ketones, the keto compounds are enantioselectively reduced to give secondary alcohols by means of microorganisms. Keto compounds of the formula R 3 NH--CHR 1 ...
5013656 Process for producing orotic acid by fermentation  
A process is disclosed for producing orotic acid, the process involves culturing in a medium a microorganism of the genus Corynebacterium which is capable of producing orotic acid and has...
4996149 Microbiological hydroxylation process of quinine, quinidine and derivatives thereof  
A process for the regiospecific and stereospecific hydroxylation of quinine, quinidine and their derivatives, in position 3S, is characterized by the use of certain microorganisms being reacted on...
4971909 Process for producing optically active compounds having pyridine skeletons  
The present invention provides a process for producing optically active compounds by a biochemical method in which specific compounds having pyridine skeletons and hydroxyl groups are reacted with...
4915842 Simple system to decompose pesticide waste water  
A hybrid chemical/biological process which is highly effective to destroy the herbicide, Atrazine, in wasterwater solutions is herein disclosed. The process comprises subjecting the atrazine...
Matches 51 - 100 out of 171 < 1 2 3 4 >