Matches 1 - 50 out of 189 1 2 3 4 >
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7611880 Enzymatic ammonolysis process for the preparation of intermediates for DPP IV inhibitors  
An enzymatic ammonolysis process is provided for the preparation of intermediates used in preparing dipeptidyl peptidase IV inhibitors wherein the enzyme Candida antarctica lipase-B is used to...
7582455 Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors  
Monatin and certain stereoisomers of monatin, such as R,R monatin and S,R monatin, as well as salts thereof, are produced using polypeptides and biosynthetic pathways. These polypeptides and...
7572607 Polypeptides and biosynthetic pathways for the production of monatin and its precursors  
Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided....
7534590 Method for producing monatin  
A solution to be treated containing monatin and impurities is treated with a nonpolar resin having aromatic rings, whereby monatin is separated from the solution. Treatment with the nonpolar resin...
7534591 Bengamide derivatives, process for preparing them, and their use  
The present invention relates to bengamide derivatives which are formed, during fermentation, by the microorganism Myxococcus virescens ST200611 (DSM 15898), to their use for treating cancer...
7432100 Variant aldolase and processes for producing an optically active IHOG and an optically active monatin using the same  
The present invention relates to variant aldolase enzymes that are modified so as to produce IHOG (4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid: IHOG), a process for producing an optically...
7405070 Method for preparing (s)-indoline-2-carboxylic acid and (s)-indoline-2-carboxylic acid methyl ester using hydrolytic enzyme  
Disclosed is a method for preparing (S)-indoline-2-carboxylic acid and (S)-indoline-2-carboxylic acid methyl ester using an inexpensive industrially available enzyme capable of assuring superior...
7371549 Aldolase, and method for producing optically active IHOG and monatin  
The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for...
7354746 Method for producing optically active IHOG and monatin  
The present invention relates to a method for producing optically active IHOG, which can in turn be used for the production of monatin. The present invention further relates to a method for...
7229803 Reaction of (di)amines in the presence of a lysine oxidase and of a reducing agent  
The invention relates to methods for reacting (di)amines as substrates in the presence of a lysine oxidase arid a reducing agent, resulting in alcohols, diols or cyclic secondary amines. In a...
7223573 Enzymatic ammonolysis process for the preparation of intermediates for DPP IV inhibitors  
An enzymatic ammonolysis process is provided for the preparation of intermediates used in preparing dipeptidyl peptidase IV inhibitors wherein the enzyme Candida antarctica lipase-B is used to...
7052885 Process for preparing heterocyclic (R)- and (S)-cyanohydrins  
A process for preparing enantiomer-enriched heterocyclic (R)- and (S)-cyanohydrins of the formula (I), where R1, R2, R3, R4 independently of one another are H, an unsubstituted or substituted C...
6953678 Use of orthoesters for the synthesis of chiral acids in biocatalyzed irreversible esterification processes  
A process for the resolution of enantiomeric mixtures of a chiral carboxylic acid, including an esterification reaction of the carboxylic acid in an organic solvent, in the presence of a...
6953679 Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof  
Fused cyclic compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions...
6936445 Enzyme preparation and method of using the same  
There is disclosed are an enzyme preparation characterized by a polymer carrier having fine pores with average radius of 200-500 Å and the enzyme is capable of converting an N-substituted cyclic...
6908752 Process for the preparation of the enant iomeric forms of 2-substituted 2- (2, 5-dioxoimidazolidin-1yl) -acetic acid derivatives  
The present invention relates to a process for the preparation of the enantiomeric forms of 2-substituted 2-(2,5-dioxoimidazolidin-1-yl)acetic acid derivatives of the formula I, wherein R 1 ,...
6905849 Process for preparing clavam derivatives by using polypeptides having β-lactam synthetase activity  
The present invention relates to a new process for the synthesis of clavam compounds, in particular clavulanic acid. In one aspect, the invention relates to Streptomyces clavuligerus β-lactam...
6642391 Amycomycin, a process for its production and its use as a pharmaceutical  
A compound named Amycomycin of the formula: is described, as well as its pharmaceutically acceptable salts and derivatives, in all their stereoisomeric and tautomeric forms. The compound is...
6638758 Process for the enzymatic resolution of lactams  
A method of separating enantiomeric lactam esters. The lactam esters are contacted with a biocatalyst, such as an enzyme or a microorganism, in a solution wherein only one enantiomer is selectively...
6635455 Process for producing pyrrole-2-carboxylic acid  
A process for producing pyrrole-2-carboxylic acid which comprises the steps of: allowing a microorganism that is derived from the genus Serratia, is capable of catalyzing decarboxylation of...
6632659 Apparatus and method for UV oxidation and microbiological decomposition of organic waste air  
The invention discloses an apparatus and a method for UV oxidation and microbiological decomposition of organic waste air. The invention provides an integrated system consisting of UV oxidation as...
6617451 Enantioselective acylation of cis racemic azetidinones  
Cis-β-lactam compounds having structure (II) are described herein which are prepared by enantioselective acylation of the free amine in the presence of Penicillin G Amidase.
6613550 Microbial process for preparation of optically active 3-hydroxypyrrolidine derivatives  
The present invention is directed to a process for the production of compounds of the formula: from a compound of the formula comprising hydroxylating a compound of the formula I in the...
6610518 Enzymatic oxidations  
The following invention relates to a process for oxidizing alkyl groups attached directly or via a linker, to a sulfonamide moiety (II) by the use of cytochrome P450 enzymes, to give the...
6599930 Coniosetin and derivatives thereof, process for the preparation and the use thereof  
The present invention relates to novel active substances (coniosetin and coniosetin derivatives) of the formula I which are produced by the microorganism Coniochaeta ellipsoidea Udagawa (DSM...
6582952 Method for eliminating a nitrogenated heterocyclic, or aromatic, compound in an effluent  
This invention relates to a method for the removal of a nitrogen containing heterocyclic or aromatic compound, comprising at least one nitro group, in an effluent by the conversion of said, at...
6444450 Large-scale production of polyphenols or polyaromatic amines using enzyme-mediated reactions  
A process for large-scale, low cost, batch or continuous production of polyphenols using enzyme-mediated reactions and methods for recycling non-consumed reactants.
6410279 Process for producing optically active azetidine-2-carboxylic acid derivative  
There is provided a process for producing N-substituted azetidine-2-carboxylic acid of the formula I: wherein R 1 denotes an aralkyl group or an arylated lower alkoxycarbonyl group and *...
6410265 Gene encoding a putive efflux protein for solvents/antibiotics in Pseudomonas mendocina  
This invention relates to the isolation of a novel putative efflux gene from Pseudomonas mendocina . The putative efflux gene is useful for probing an organism's efflux system to gain an...
6391597 Method for producing optically active 1-(4-t-butylphenyl)-5-oxo-3-pyrrolidine carboxylic acid and/or an enantiomeric ester thereof  
A method for producing an optically active 1-(4-t-butylphenyl)-5-oxo-3-pyrrolidine carboxylic acid and/or an enantiomeric ester thereof which includes treating an ester of...
6387687 Process for producing indolmycin  
A microorganism having indolmycin-producing ability and tryptophan analogue resistance is provided, and indolmycin or its salt can be produced efficiently by cultivating such microorganism in a...
6379935 Method of producing α-halo-α,β-saturated carbonyl compounds from the corresponding α,β-unsaturated compounds  
A method of producing an α-halo-α,β-saturated carbonyl compound from an α-halocarbonyl compound having an α, β-carbon-carbon double bond by reducing said α,β-carbon-carbon double bond using...
6361979 Microbial conversion of 2-methylquinoxaline  
The present invention relates to processes for the microbial oxidation of 2-methylquinoxaline to 2-quinoxalinecarboxylic acid which comprise contacting 2-methylquinoxaline with a microorganism, or...
6303354 Microbial production of indigo  
There is provided an improved process for the biosynthetic production of indigo, the improvement comprising removing unwanted by-products such as isatin or indirubin from the broth in which such...
6214610 Process for the preparation of optically active N-benzyl-3-pyrrolidinol  
The invention provides an efficient method of producing optically active N-benzyl-3-pyrrolidinol by an enzymatic reaction stereoselectively reducing N-benzyl-3-pyrrolidinone. The invention consists...
6180375 Microbial biotransformation  
The present invention relates to the use of microorganisms of the Monosporium and Thamostylum genera to diastereoselectively O-demethylate pharmaceutical intermediates, to produce compounds of the...
6136591 Bioresolution of N-acylazetidine-2-carboxylic acids  
Process for obtaining an enantiomerically enriched N-acylazetidine-2-carboxylic acid, wherein a racemic N-acylazetidine-2-carboxylic acid ester is contacted with an enzyme that displays...
6133001 Stereoselective microbial reduction for the preparation of 1-(4-fluorophenyl)-3(R)-[3(S)-Hydroxy-3-(4-fluorophenyl)propyl)]-4(S)-(4 -hydroxyphenyl)-2-azetidinone  
A process for the stereoselective microbial reduction of compound of formula II to compound of formula I ##STR1## comprising adding compound of formula II to a medium, medium and buffer, medium and...
6121025 Process for producing optically active 3-quinuclidinol derivatives  
The present invention relates to a process for producing optically active 3-quinuclidinol or derivatives, wherein a racemic 3-quinuclidinol ester represented by the general formula (I): ##STR1##...
6087137 Preparation of hydroxy compounds by bioconversion with dioxygenase  
A process for preparing a compound of Formula (3) in which R 2 is --H; ##STR1## which comprises the steps: i) conversion of a compound of Formula (1) into a compound of Formula (2) using a...
6063935 Azetidine derivative, bifidobacterium division-promoting composition containing the same, and a process for production thereof  
An azetidine derivative is provided which includes 3,3-dihydroxyazetidine represented by Chemical Formula (I) or a salt thereof: ##STR1## A composition containing the azetidine derivative, and a...
6046340 Imidazole containing pseudodipeptide product and compositions containing the same  
Product pseudodipeptide of general formula: ##STR1## in which A is: a) under the form: ##STR2## B represent an amine which nitrogen atom which is directly linked to the atom of carbon and chosen...
5989876 Colorant precursors derivable from cells of plants of the genus medicago, process for their preparation and use thereof for the preparation of colorants  
Colorant precursors, which are present in the cells of plants belonging to the genus Medicago, such as alfalfa, can react with quinones so as to yield colorants which can be used in dyeing...
5968788 Method for producing folic acid  
Disclosed is a method for producing folic acid, comprising incubating yeast having the ability to produce folic acid of 0.3 mg or more or incubating bacteria having the ability to produce folic...
5922582 Indole alkaloid type compound 0089-D  
The present invention relates to compound 0089-D having excellent antitumor activity and antimicrobial activity, represented by the general formula (I): ##STR1## or pharmaceutically acceptable...
5919672 Resolution of trans-2-(alkoxycarbonylethyl)-lactams useful in the synthesis of 1-(4-fluoro-phenyl)-3(R)- (S)-hydroxy-3-(4-fluorophenyl)-propyl!-4(S)-(4 -hydroxyphenyl)-2-azetidinone  
A process for the microbiological or enzymatic hydrolytic resolution of racemic trans-2-(alkoxycarbonylethyl) lactams of the formula I: ##STR1## wherein R is C 1 -C 7 alkyl, 2,2,2-trifluoroethyl...
5869719 Transgenic plants having increased biotin content  
The present invention reveals that biotin biosynthesis in a plant is enhanced when the level of one or more of the enzymes in the plant biotin biosynthetic pathway is increased. Based upon this...
5801023 Antiparasitic pyrrolobenzoxazine compounds  
This invention provides compounds of the following chemical formula or their pharmaceutically-acceptable salts: ##STR1## wherein R is hydrogen or chloro. Also, the present invention provides a...
5766893 Biotechnological process for the preparation of cyclic s-alpha-imino carboxylic acids and r-alpha-imino carboxamides  
Microorganisms of interest are capable of utilizing α-imino carboxamides, in the form of the racemate or of its optically active isomers, of the general formula ##STR1## wherein A together with...
5763232 Method for producing 3-hydroxy nitrogen-containing six-membered cylic compound  
A method for producing a 3-hydroxy nitrogen-containing six-membered cyclic compound is provided. Namely, microbial cells of a microorganism and/or a preparation obtained from the microbial cells is...
Matches 1 - 50 out of 189 1 2 3 4 >