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7595199 |
Method of detecting amyloid-like fibrils or protein aggregates
The present invention relates to methods of detecting the presence of detergent- or urea-insoluble amyloid-like fibrils or protein aggregates on filters. Preferably, said fibrils or aggregates are...
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7582485 |
Method and device for detecting ammonia odors and helicobacter pylori urease infection
The invention provides a breath testing device which visually indicates the presence of ammonia in a patient's breath, in particular ammonia from helicobacter pylori urease infection. The breath...
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7540948 |
Blood urea nitrogen (BUN) sensor
A BUN (blood urea nitrogen) sensor containing immobilized carbonic anhydrase and immobilized urease for the in vitro detection of urea nitrogen in blood and biological samples with improved...
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7485855 |
On-probe sample cleanup system and method for MALDI analysis
A system and method for cleanup of biological samples from contaminants prior to spectroscopy analysis. The system includes a support configured to hold a sample including a liquid having at least...
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7476551 |
Diagnosing atherosclerosis risk by measuring carbamylated low density lipoprotein levels
The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of: measuring the level of carbamylated LDL in a sample obtained...
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7445908 |
Detection of oxidizing agents in urine
A method of detecting oxidants in a biological sample comprising: adding a source of ferrous ions to said sample, whereby the presence of oxidants in said sample oxidize at least a portion of said...
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7358062 |
Method for diagnosing atrophic gastritis
The press device for a paper web, such as a calender, contains a flexible moving element ( 1 a ) forming an endless structure, said element forming the shell ( 1 ) of a roll, the press device...
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7344852 |
Crystallization of dipeptidyl peptidase IV (DPPIV)
Provided are crystals relating to DPPIV and its various uses.
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7264800 |
Method and composition for inhibiting cancer cell growth
Improvements in methods of treating cancer with weakly basic anti-cancer compounds are provided. In one aspect, the invention provides an improvement in a method of treating cancer cells whose...
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7179609 |
Screening method for gastritis
A screening method for gastritis is provided. The method involves the serological measurement of at least two of the following analytes: H,K-ATPase antibodies, Helicobacter pylori antibodies and...
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7132236 |
Composition and method for optimized hybridization using modified solutions
The invention provides a composition, kit and method for hybridizing a probe and target at a temperature lower than their standard hybridization temperature. The chemical component added to the...
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7125681 |
Methods for detection of disease-associated antibodies in urine
The present invention provides methods and diagnostic kits for the detection of disease-specific antibodies in urine containing sample. The present invention is also directed toward methods for...
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7087398 |
Method for detecting urease
A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. In one embodiment, the system includes a first composition separated from a second composition....
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7022494 |
Detection of potassium ions using ion-sensitive enzymes
The invention relates generally to the field of potassium ion detection. In particular, the invention provides methods and kits for assaying for potassium ions in a sample, using, a...
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7008777 |
System for the detection of urease and method for using same
A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. In one embodiment, the system includes a first composition separated from a second composition....
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6998250 |
Method for detecting Helicobacter pylori
A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. The system includes a carrier having a first well and a second well. A first composition is...
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6872517 |
Early diagnosis of cancerous and precancerous conditions by leakage of signature peptides and carbohydrates into the bloodstream
The present invention involves the early diagnosis of cancerous or precancerous conditions in the gastrointestinal tract by detection of a backleak of signature proteins or carbohydrates in a...
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6855828 |
Detection of hypoxia
Nitroaromatic compounds and immunogenic conjugates comprising a novel nitroaromatic compound and a carrier protein are disclosed. The invention further presents monoclonal antibodies highly...
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6753159 |
Uric acid assay device with stabilized uricase reagent composition
The invention provides an enzyme-based device and process for manufacture of the device in a shelf-stable form. The device consists of a dry phase test strip useful in detecting the presence and...
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6733984 |
Sensor for analyzing components of fluids
A sensor is provided that is useful for assaying a component of a biological fluid such as blood, urine or milk, and comprises a chamber having an inlet, a liquid containing portion and a vapor...
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6677129 |
Method for detecting Helicobacter pylori infection
A method for oral sampling and rapid, specific detection of the urease activity associated with H. pylori infection in humans without the need for sample incubation. The method involves the steps...
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6649360 |
Test strip for detecting gastric problems based on the presence of urease
A testing apparatus for detecting urease in a gastric material taken from a human or lower animal subject is disclosed, the apparatus comprising a dry indicating composition responsive to urease, a...
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6642016 |
Biosensor and its use to indicate the status of a product
A biosensor comprises a unit, comprising a substrate and an enzyme, which when brought into contact with the substrate is adapted to affect the substrate so that its conductivity changes as a...
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6627394 |
Diagnostic pad
An indicator system including two pH sensitive indicators and a reagent is disclosed. The indicator system can be integrated into a number of products such as sanitary napkins or panty shields and...
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RE38088 |
Immunoassay for H. Pylori in fecal specimens
A process for the determination of H. Pylori in a fecal specimen comprising (a) dispersing a fecal specimen suspected of carrying H. pylori in a sample diluent; (b) contacting the fecal specimen in...
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6548309 |
Procedure for assay of liquids containing undissolved solids, semisolids or colloids
In qualitative or quantitative assays which employ a test device comprising a test strip pretreated for detection of a specified target analyte dissolved in a liquid medium, the presence of solid,...
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6521416 |
Determination of the amount of hLHβ core fragment in a sample from a subject and uses thereof
The present invention provides a method for predicting the likely timing of the onset of menopause for a perimenopausal female subject by determining the amount of hLHβcf in a sample from the...
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6403099 |
Conjugates formed from heat shock proteins and oligo-or polysaccharides
The present invention provides conjugate compounds comprising at least one heat shock protein or portion thereof including at least one immunostimulatory domain and at least one capsular...
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6380380 |
Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
Kits and methods for measuring enzyme activities and metabolites using NAD analogs and NADP analogs are disclosed. The analogs can be used as replacements for NAD and NADP cofactors in analytical...
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6379910 |
Measuring apparatus and method for material or organism inducing PH-change of substrate solution
One end of a thin-tube type solid phase in which a receptor specific for a material or an organism to be measured which can induce a pH-change of substrate solution is immobilized is soaked in a...
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6376197 |
Diagnosis of interstitial cystitis
Interstitial cystitis (IC) is a chronic bladder disease for which the exact etiology is unknown and for which there is no reliably effective treatment. However, it is known that the bladder...
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6312918 |
Examination method of infection with Helicobacter pylori
There are described a simple examination method of infection with Helicobacter pylori possibly presenting in a gastric mucosa, and a device therefor. The examination is conducted by collecting gas...
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6274139 |
Topoisomerase I
Topoisomerase I polypeptides and DNA and RNA encoding such Topoisomerase I polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are...
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6235491 |
Assay utilizing magnetic particles
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6225462 |
Conjugated polysaccharide fabric detergent and conditioning products
A polysaccharide conjugate comprises a polysaccharide with an attached entity having a molecular weight of at least 5000, the polysaccharide conjugate being capable of binding to cellulose....
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6186946 |
Urinalysis stick for animals
A urinalysis stick for animals comprising a chemical reaction agent at an end, a color sample showing the discoloration stage at a rear end, and a half cut portion or a half fold portion provided...
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6187556 |
Composition, kit, and method for detecting Helicobacter pylori in biopsy
Disclosed are a composition for detecting Helicobacter pylori including urea 0.5 to 4 percent by volume, potassium phosphate 0.05 to 0.2 percent by volume, phenate reagent solution 0.8 to 1.7...
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6156346 |
Urease-responsive delivery systems for diagnostic and therapeutic applications
A delivery system that releases a diagnostic marker or therapeutic agent in a manner sensitive to the concentration of urease in a physiological compartment, particularly the gastrointestinal...
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6114176 |
Method for measuring the concentration of a substance in a solution
Methods and apparatus for measuring the concentration of decomposable substances, such as urea, are disclosed. The disclosed methods include adding a gaseous buffer, such as CO 2 , to the solution...
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6054577 |
Oligosaccharides from enzymatic cleavage of fucoidan
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5989840 |
Estimation of active infection by heliobacter pylori
Disclosed is a diagnostic apparatus for estimating an active Heliobacter pylori infectious agent in saliva, comprising in combination an immunoassay chamber in which a first portion of said saliva...
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5965379 |
Method for measuring endogenous cytokines
The present invention relates to methods for measuring endogenous cytokines in blood. The method accurately measures the cytokines in the blood in the presence of substances that bind the cytokines...
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5942409 |
Process for identification of substances modulating ureI dependent mechanisms of Helicobacter pylori metabolism
The present invention provides a screening process for the identification of anti-helicobactericidal substances modulating ureI dependent mechanisms of gastric Helicobacter metabolism. Gastric...
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5916757 |
Specific binding assay using enzyme inhibitor and anti-inhibitor antibodies
Specific binding ligands can be detected with an assay which utilizes an immobilized receptor for the ligand, an immobilized reporter enzyme, an inhibitor antibody and a a water-soluble conjugate...
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5897993 |
Method of determining the number of bacteria quickly and a device for determining the number of bacteria
A method of determining the number of bacteria in a sample which involves introducing a sample containing bacteria into a tubular filtering vessel holding therein a hydrophobic filter for bacterial...
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5888755 |
Method of determining the amount of cholesterol in a high-density lipoprotein
Provided is a method of determining the amount of cholesterol in high-density lipoprotein (HDL), which comprises reacting an HDL-containing sample with cholesterol esterase and cholesterol oxidase...
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5888760 |
Universal test systems and methods of use thereof for identifying multiple families of microorganisms
The present invention relates to a universal test systems and methods of use thereof for identifying a microorganism among at least two groups of widely divergent microorganisms. The universal test...
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5888828 |
Kit for measuring urea nitrogen
A method of measuring urea nitrogen on the basis of the ultraviolet absorption of urease-GLDH by a reaction rate method, which method not only permits accurate measurement of a sample containing a...
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5846752 |
Mutant urease and method of use for determination of urea
A mutant urease of Klebsiella aerogenes characterized as αH219Q having a glutamine (Q) in position 219 in place of histidine (H). The resulting enzyme has a low affinity for substrate (high value...
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5804402 |
Reagent
This invention relates to a reagent for enzymatic determination of an analyte concentration in a patient wherein the degree of oxidation of a coenzyme is measured, characterized in that said...
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