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8178311 |
Multiple quantification of cholesterol in low density lipoprotein
The present invention is intended to provide a method for simultaneously measuring cholesterol in low density lipoprotein and total cholesterol as test components in blood. Specifically, a method...
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8163512 |
Method for determination of cholesterol in small dense low-density lipoprotein
A method for determination of sdLDL-C in a reaction solution containing a surfactant that preferentially inhibits the reaction of sdLDL-C with enzymes for cholesterol measurement such as...
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8158375 |
Polymer and method of measuring cholesterol therewith
It is an object of the present invention to provide the method for determining cholesterol in lipoprotein and reagent for determining cholesterol comprising the polymer, and the present invention...
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8158435 |
Tandem mass spectrometry for detecting and/or screening for conditions associated with altered sterols
Embodiments of the present invention provide for detecting and/or screening for conditions associated with altered sterols by derivatization of sterols to provide suitable sensitivity and...
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8137977 |
Lipidomic approaches to determining drug response phenotypes in cardiovascular disease
The present invention concerns the application of lipidomics to statin treatment for disorders such as cardiovascular disorders. Hence, the invention provides, among other things, a method of...
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8133454 |
Biological material fixed region enclosing tip, biological material fixed region treatment apparatus, and treatment method thereof
A biological material fixed region enclosing tip, a biological material fixed region treatment apparatus, and a treatment method thereof. An object is to enable processing to be performed while a...
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8124367 |
Device for applying a detector reagent to the skin for measuring cholesterol
The present invention provides a method and apparatus for non-invasive measurement of skin cholesterol. More particularly, one aspect of the invention provides for a device to apply a detector...
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8119360 |
Method, reagent and kit for determination of cholesterol in remnant-like particles (RLP)
The present invention provides a method, a reagent and a kit for simple and sensitive determination of cholesterol in remnant-like particles without separation of components of a sample. A method...
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8101062 |
System and methods for determination of analyte concentration using time resolved amperometry
A method for determining a concentration of an analyte is disclosed. The method includes applying a potential excitation to a fluid sample containing an analyte and determining if a current decay...
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8088625 |
Method for detection of familial combined hyperlipidemia
An object of the present invention is to provide an excellent method for detection and diagnosis of familial combined hyperlipidemia. The present invention relates to a method for detection of...
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8030081 |
Reagent for quantitative determination of small, dense LDLs
A reagent for fractional measurement of small, dense LDLs without pretreatment of a specimen, which is adaptable to a rapid and convenient autoanalyzer, is provided. A method for quantitatively...
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7989179 |
LXR ligand testing method
A method of easily measuring whether or not an LXR ligand has the function of effecting, e.g., increasing, plasma triglyceride concentration and/or LDL cholesterol concentration in a mammal by...
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7981598 |
Preventive/remedy for respiratory diseases
It is intended to provide a compound inhibiting the activity of a protein having an amino acid sequence which is the same or substantially the same as one of the amino acid sequences represented by...
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7981683 |
Method and apparatus for analyzing vitamin E in lipoproteins
A method of analyzing vitamin E components in a lipoproteinby subjecting a lipoprotein-containing sample to ion exchange chromatography to separate the lipoprotein, reacting the separated...
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7964372 |
Size self-limiting compositions and test devices for measuring analytes in biological fluids
A test strip or electrochemical sensor for measuring the amount of an analyte in a biological fluid, e.g. the glucose content of whole blood, includes a size self-limiting reagent formulation...
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7939287 |
Methods of identifying a subject having or at risk of having or developing coronary artery disease
Provided herein are compositions and methods for identifying individuals at risk for developing coronary artery disease (CAD).
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7851174 |
Method for quantitatively determining cholesterol in high density lipoproteins and reagents therefor
A method for quantitatively determining cholesterol in high-density lipoprotein in a sample, which comprises: reacting a sample with i) cholesterol esterase and cholesterol oxidase or ii)...
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7824879 |
Device and method for measuring LDL-associated cholesterol
An assay device and method for determining the concentration of low density lipoprotein (LDL)-associated cholesterol (LDL-C) in a body-fluid sample, such as a blood sample is described.
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7811780 |
Method for measurement of cholesterol in high-density lipoprotein
The present invention provides a method, a reagent and a kit for the simple and accurate measurement of HDL cholesterol. The method for the measurement of cholesterol in high-density lipoprotein in...
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7811779 |
Method of multiquantification for cholesterol of low-density lipoprotein
Provided is a method of stabilizing a reagent that allows simultaneous quantification of LDL cholesterol and total cholesterol by a single measurement by suppressing spontaneous color development...
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7803587 |
Method for developing culture medium using genome information and in silico analysis
A method for developing a culture medium using genome information and in silico analysis. In one implementation, the method involves developing a minimal synthetic medium, including the steps of...
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7799537 |
Cholesterol measuring reagent containing a cholesterol esterase
There are provided a method and reagent for measuring cholesterol in remnant-like lipoprotein in a sample with high sensitivity by more simple operation. The method for measuring cholesterol in...
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7795038 |
High-density lipoprotein assay device and method
An assay device and method for measuring the concentration of HDL-associated cholesterol in a blood-fluid sample are described. The assay design prevents interference by reagents used for such...
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7772007 |
Assay device for direct measurement of LDL cholesterol
An assay device and method for measuring the concentration of LDL-associated cholesterol in a blood-fluid sample are described. The method employs selective precipitation of VLDL and chylomicrons...
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7682831 |
Method of measuring lipid in specific lipoprotein
A method of measuring a lipid in a specific lipoprotein characterized by using a polycyclic polyoxyalkylene derivative at least in the step of determining the specificity of the measurement of the...
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7575884 |
Test piece for measuring high-density lipoprotein (HDL) cholesterol
The present invention relates to a test piece having a simple structure, by which HDL cholesterol can be measured easily using a small amount of specimen. A reagent layer (2) is formed on a support...
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7527932 |
Method of using physiological markers to estimate cardiovascular risk
An individual's risk profile for developing a cardiovascular disorder or for experiencing a cardiovascular event is determined by 1) measuring levels of certain stress-evoked proteins including...
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7507551 |
Multiple quantification method for cholesterol in low-density lipoproteins
The present invention is intended to provide a method for simultaneously measuring cholesterol in low density lipoprotein and total cholesterol as test components in blood. Specifically, a method...
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7491542 |
Test device for determining the concentration of LDL-cholesterol in a sample
The present invention provides a test device for determining the concentration of LDL-cholesterol in a sample. The test device has a continuous solid surface with at least one reaction area on the...
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7402404 |
Assay method for measurement of net cholesterol flux
The present invention relates to an assay for determining net cholesterol flux from lipid loaded cells in the presence of an acceptor (e.g., serum). The present invention also relates to a method...
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7361482 |
Method for detecting intracellular cholesterol
The present invention relates to a method of detecting intracellular cholesterol. The method provides contacting a permeabilized cell with labeled cθ complex. Methods of using this detection ...
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7348158 |
Method of quantifying cholesterol in high density lipoprotein and reagent compositions
A method for specifically quantifying HDL cholesterol in which cholesterol in lipoproteins other than HDL is erased in the first step, and HDL cholesterol is specifically quantified in the second...
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7335483 |
Method of pretreatment of sample for quantitating cholesterol and method for quantitating cholesterol in specific lipoproteins by using the same
A method of a pretreatment of a sample for quantitating cholesterol characterized by, before measuring cholesterol contained in specific lipoproteins, treating the sample containing lipoproteins...
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7279296 |
Compositions and methods for lipoprotein uptake assays
Provided herein are compositions and methods for lipoprotein uptake assay. These compositions and methods may be used for the lipoprotein uptake assays, including high-throughput assays. The...
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7270971 |
Fluorescence assay for measuring the rate of cholesterol ester transfer
An improved method of obtaining fluorescence measurements which may be used as a measure of the CETP-catalyzed rate of transfer of a lipophilic non-polar fluorescent cholesteryl ester between...
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7250304 |
Functional assay of high-density lipoprotein
This invention provides novel assays that are prognostic and/or diagnostic for atherosclerosis or risk of atherosclerosis. It was discovered that high density lipoprotein (HDL) or components...
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7238494 |
Direct assay of cholesterol in skin samples removed by tape stripping
Skin cholesterol is measured by applying an adhesive tape onto a selected area of the skin to adhere the tape to the selected skin area and stripping the tape off the selected skin area to obtain a...
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7223546 |
Method for measuring the amount of constituent contained in a specific lipoprotein
There is provided a method and kit for measuring the amount of an objective constituent contained in a specific lipoprotein in a biological sample such as serum and plasma, specifically for...
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7208287 |
Reagent set and method for detecting cholesterol in a high-density lipoprotein or low density lipoprotein
A method for quantitating a specific component in lipoproteins contained in a biological sample, for example, HDL (high-density lipoprotein), LDL (low-density lipoprotein) or VLDL (very low-density...
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7202047 |
Aqueous method for determining cholesterol in remnant-like particles using cholesterol esterase, phospholipase, surfactant and cholesterol oxidase or dehydrogenase
The present invention provides a simple and sensitive aqueous method for determining cholesterol in remnant-like particles in a biological sample without the separation of components of the sample....
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7179612 |
Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality
A method for diagnosing a condition of a patient involves the steps of (a) adding one or more reagents to a test sample from a patient, the test samples comprising at least part of a blood sample...
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7087397 |
Method for determining HDL concentration from whole blood or plasma
A multilayer test strip and method of using the test strip for determining concentration of HDL cholesterol in a whole blood sample. The inventive test strip includes a two-stage blood separation...
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7081509 |
Method for producing highly functional, hyper branched polyester by means of enzymatic esterification
The present invention relates to a process for preparing highly functional hyperbranched polyesters which comprises reacting a reaction solution comprising solvent and (a) one or more dicarboxylic...
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7074581 |
Reagent for assaying lipid
Effective stabilizing amount at least of one antioxidant is added to a composition containing an esterase and surfactant(s).
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7052864 |
Bioanalytical measuring method using oxidases and lanthanoid-ligand complexes
The present invention concerns biological methods of determination using enzymes from the group of oxidases and using optical indicators from the group of lanthanoid-ligand complexes.
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7049130 |
Diagnostic sanitary test strip
An improved multi-layered diagnostic sanitary test strip for receiving a heterogenous fluid, such as whole blood, to test for presence and/or amount of a suspected analyte in the fluid by...
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7049086 |
High-throughput screening assay for cholesterol inhibitors and inhibitors identified thereby
The present invention provides a high-throughput screening assay to identify test agents as cholesterol inhibitors via mutant NCP1 mammalian cells. Also provided are cholesterol inhibiting agents...
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7026111 |
Methods and reagents for improved cell-based assays
The ability to efficiently determine the state of enzyme expression in cells has long been desired as material to the diagnosis of disease. This invention relates to cytoenzymology, and more...
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6986998 |
Method of analyzing components in biological samples
There is provided a method for a selective assay of component, particularly cholesterol, in very low-density lipoprotein (VLDL) which is one of serum lipoproteins. In the assay, an enzymatic...
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6979552 |
Method of lipid assay and reagent for use therein
A method of lipid assay characterized by assaying the lipids contained in a blood component in the presence of an organic silicon compound. The method can cause specific conditions for direct...
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