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8163871 |
Enzymatic reactions in the presence of keto acids
Conversion in vitro of X-Gly to X-alpha-hydroxy-Gly or X-NH2 (X being a peptide or any other compound having a carbonyl group capable of forming a covalent bond with glycine) is accomplished...
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8114639 |
Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family with attenuated expression of the sfmACDFH-fimZ cluster or the fimZ gene
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which...
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8076106 |
Method to increase the yield and improve purification of products from transaminase reactions
A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to...
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8071331 |
Method of producing amino acid metal chelates
A method of producing amino acid metal chelates includes producing an amino acid ligand by enzymatically hydrolyzing bacterial cells, and reacting the amino acid ligand with a metal cation.
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7888077 |
Method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family with attenuated expression of the kefB gene
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Pantoea,...
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7867400 |
Production of a fermentation product
A process of separating suspended solids from a fermentation liquor by subjecting the liquor to a solids-liquid separation stage, wherein the fermentation liquor is produced in a fermentation...
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7829657 |
Polycationically charged polymer and the use of the same as a carrier for nucleic acid
Disclosed is a composition for the delivery of nucleic acid to target cells or tissues, which comprises a polycationically charged polymer as a carrier of nucleic acid. The polycationically charged...
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7811798 |
Method for producing an L-amino acid by fermentation using a bacterium having an enhanced ability to utilize glycerol
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which...
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7771976 |
Method for producing a non-aromatic L-amino acid using a bacterium of the Enterobacteriaceae family having expression of the csrA gene attenuated
The present invention provides a method for producing a non-aromatic L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or...
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7598062 |
Process for the production of L-amino acids using strains of the family enterobacteriaceae that contain an attenuated fruR gene
A process for the production of L-amino acids, in particular L-threonine, in which the following steps are carried out: (a) fermentation of the microorganisms of the family Enterobacteriaceae...
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7588923 |
Method to increase the yield and improve purification of products from transaminase reactions
A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to...
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7582444 |
Use of flocculating agents for separating the solid residue in hydrolysed fermentation substrates
Process for improving the separation efficiency of residual solid matter from the liquid phase of an aqueous acid hydrolysate of a naturally occurring polysaccharide comprising dissolved sugars,...
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7455997 |
Production of fermentation product
A process of producing fermentation product comprising the steps of, (i) forming an acidified suspension of particulate plant derived material comprising a first polysaccharide which is more...
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7432085 |
Method for producing L-amino acid
In a method for producing an L-amino acid by culturing a microorganism having an ability to produce an L-amino acid in a medium to produce and accumulate the L-amino acid in the medium and...
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7399616 |
Enzymatic synthesis of Nα-acyl-L-arginine esters
The invention relates to a process for preparing a Na-acyl-L-arginine ester, derived from fatty acids and esterified dibasic amino acids, according to the following formula (I), where: X— is B...
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7300776 |
L-amino acid-producing bacterium and a method for producing L-amino acid
An L-amino acid-producing strain of Escherichia coli is bred by modifying an Escherichia coli K12 strain or a derivative thereof so as to become resistant to L-valine and have an ability to produce...
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7160703 |
Nucleotide sequences coding for the PtsI protein
The present invention provides nucleotide sequences from Coryneform bacteria which code for the PtsI protein and a process for the fermentative preparation of amino acids using bacteria in which...
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7157251 |
Process for the racemization of N-protected amino acids using racemase
The present invention relates to the processes of racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected...
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7129059 |
Process for the preparation of compounds with enhanced optical purity
A process for preparation of a compound with enhanced optical purity is disclosed wherein a mixture of the enantiomers of a chiral amine is brought into contact with an enzyme having peptide...
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6953677 |
Recombinant L-N-carbamoylase from Arthrobacter aurescens and method of producing L-amino acids therewith
A novel rec-L-N-carbamoylase from Arthrobacter aurescens and its method of use for producing L-amino acids. The recombinantly produced L-carbamoylase is unexpectedly stable, so that an industrial...
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6919190 |
Regulation of carbon assimilation
The present invention provides a method of increasing the productivity of a microorganism by improving the assimilation of carbon dioxide. Specifically, the invention provides a polypeptide having...
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6821760 |
Methods for producing L-aspartic acid
This invention relates to a method for producing L-aspartic acid comprising treating an ammonium fumarate solution with aspartase to generate an ammonium L-aspartate solution; adding fumaric acid...
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6808914 |
Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene
The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the...
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6806070 |
Use of bacterial extracts of the pseudomonadaceae family as cosmetic agents
Use of an extract of bacterium from the family Pseudomonadaceae in the production of cosmetic compositions in particular for combating ageing of the skin.
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6730518 |
Method for preventing photooxidation or air oxidation in food, pharmaceuticals and plastics
Disclosed is a method of reducing photooxidation or air oxidation in susceptible materials such as food, plastics or pharmaceuticals comprising mixing the material with an antioxidation composition...
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6656710 |
Process for the production of amino acids using racemase and acylase
The present invention relates to the processes of racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected...
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6617127 |
Synthesis and recovery of aspartame involving enzymatic deformylation step
The invention relates to the synthesis of aspartame involving enzymatic deformylation of an N-formyl-α-L-aspartyl-L-phenylalanine compound by treatment with an enzyme having formylmethionyl ...
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6551803 |
Method for purification of amino acid containing solutions by electrodialysis
A process is described for purifying an amino acid-containing solution by means of electrodialysis, wherein an amino acid-containing solution is employed which is obtained from the fermentation for...
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6420166 |
Process for the preparation of D-asparagine derivatives
The present invention provides a process for the preparation of D-asparagine derivatives of formula I wherein R1 is an amino protecting group and R2 is an alkyl, a substituted alkyl or a group of...
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6410265 |
Gene encoding a putive efflux protein for solvents/antibiotics in Pseudomonas mendocina
This invention relates to the isolation of a novel putative efflux gene from Pseudomonas mendocina. The putative efflux gene is useful for probing an organism's efflux system to gain an...
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6379934 |
Process for the fermentative preparation of L-amino acids using coryneform bacteria
The invention provides a process for the fermentative preparation of L-amino acids using coryneform bacteria, in which the subunit carrying the biotin-carboxyl carrier protein domain and the...
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6344348 |
Process for the production of aspartic acid condensate
The invention provides a process for the production of aspartic acid poly-condensate from a carbohydrate comprising the steps of: fermenting a carbohydrate-containing medium by means of a fumaric...
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6300105 |
Methods for producing a succinimide polymer, an aspartic acid polymer and L-aspartic acid
A succinimide polymer is produced by thermally polymerizing an ammonium salt of aspartic acid in the presence of an acid catalyst such as a boric acid catalyst. Another amino acid may be added for...
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6280980 |
Process for the production of L-aspartic acid
A process for production of L-aspartic acid comprising (1) contacting (A) an enzyme-containing material having maleate isomerase activity and aspartase activity, or (B) an enzyme-containing...
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6258572 |
Process for preparing L-aspartic acid
An improved process for preparing L-aspartic acid by enzyme-catalyzed reaction of fumaric acid with ammonia, in which process L-aspartic acid is precipitated out by nitric acid and the resultant...
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6238895 |
Production of aspartic and malic acids with microbacterium
The use of strains of the genus Microbacterium for the production of organic acids or amino acids by the enzymatic conversion of a fumaric acid to the organic acid or amino acid desired, as well as...
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RE37187 |
Aminopeptidase GX, and a method of hydrolyzing a protein with the same
An aminopeptidase is provided which efficiently decomposes a low-molecular-weight peptide containing glutamic acid or aspartic acid in its sequence. A method of hydrolyzing a peptide or protein by...
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6214589 |
Method for producing L-aspartic acid
This invention relates to a method for producing L-aspartic acid, comprising the steps of: immobilizing microbial cells containing aspartase to produce an immobilized aspartase; feeding an ammonium...
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6168940 |
Protein having ethylenediamine-N,N'-disuccinic acid:ethylenediamine lyase acitivity and gene encoding the same
The present specification relates to a DNA comprising a nucleotide sequence coding for a polypeptide having ethylenediamine-N,N'-disuccinic acid:ethylenediamine lyase activity, the polypeptide...
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6150142 |
Process for production of L-aspartic acid
A process for producing crystalline L-aspartic acid is disclosed essentially consisting of the steps of preparing a mix solution containing fumaric acid, ammonia and an alkaline metal hydroxide,...
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6143552 |
Process for producing L-amino acids by fermentation
The present invention provides a process for producing an L-amino acid which comprises culturing in a nutrient medium a microorganism which is capable of producing the L-amino acid and which can...
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6133018 |
Enzymatic synthesis of chiral amines using -2-amino propane as amine donor
2-Aminopropane is used as the amine donor in the stereoselective synthesis of a chiral amine from a ketone with a transaminase. In a typical embodiment, (S)-1-methoxy-2-aminopropane is prepared by...
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6103508 |
Method for removing fumarase activity, microorganisms obtainable by the method, and production of optically active aminopolycarboxylic acids using the microorganisms
This invention relates to a method for removing fumarase activity from a microorganism or processed product thereof having ethylenediamine-N,N'-disuccinic acid ethylenediamine lyase activity, which...
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6071728 |
Process for the production of crystalline aspartic acid
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6063615 |
Enzymatic acylation of amino acid esters using a carboxylic acid ester substituted with oxygen on the alpha carbon
Disclosed is a process for preparing acylated amino esters and a process for preparing optically active amino esters from racemic amino esters with a carboxylic ester as acylating agent, whose acid...
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6015704 |
Mutant aspartase and the preparation thereof
Disclosed is a mutant aspartase comprising the amino acid sequence of a wild-type E. coli aspartase wherein the amino acid residue at one of positions 25, 123, 421 and 463 is substituted. Also...
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6011001 |
Method of protein therapy by orally administering crosslinked protein crystals
A protein such as an enzyme or antibody is immobilized by crosslinking crystals of the protein with a multifunctional crosslinking agent. The crosslinked protein crystals may be lyophilized for...
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6004768 |
Biosensors, extracorporeal devices and methods for detecting substances using crosslinked protein crystals
Proteins such as enzymes and antibodies are immobilized by crosslinking crystals of the proteins such as microcrystals having a cross-section of 10-1 mm or less with a multifunctional crosslinking...
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5981238 |
Process for producing optically active aminopolycarboxylic acid
A process for producing an optically active aminopolycarboxylic acid, such as S,S-ethylenediamine-N,N'-disuccinic acid, from a mixture of a diamine, such as ethylenediamine, with fumaric acid using...
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5976529 |
Methods of enzyme therapy by orally administering crosslinked enzyme crystals
A protein such as an enzyme or antibody is immobilized by crosslinking crystals of the protein with a multifunctional crosslinking agent. The crosslinked protein crystals may be lyophilized for...
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