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7598062 Process for the production of L-amino acids using strains of the family enterobacteriaceae that contain an attenuated fruR gene  
A process for the production of L-amino acids, in particular L-threonine, in which the following steps are carried out: (a) fermentation of the microorganisms of the family...
7588923 Method to increase the yield and improve purification of products from transaminase reactions  
A process for producing high yields of enantioselective amino acids and chiral amines by reacting a keto acid or ketone and an amino acid donor in the presence of a transaminase biocatalyst to...
7527950 Method for producing an L-amino acid by enhancing expression of the yfiK gene in an Escherichia bacterium  
A bacterium belonging to the genus Escherichia which has an ability to produce an L-amino acid, wherein the ability to produce the L-amino acid is increased by increasing expression of the yfiK...
7491519 Bacterium having ability to produce L-glutamic acid, L-proline or L-arginine and method for producing L-glutamic acid, L-proline or L-arginine  
L-Glutamic acid, L-proline or L-arginine is produced by culturing a bacterium belonging to the genus Escherichia , which is L-isoleucine auxotrophic and has ability to produce L-glutamic acid,...
7476531 Method for producing L-amino acid using bacteria belonging to the genus Escherichia  
There is provided a method for producing L-threonine, L-valine, L-proline, L-leucine, L-methionine and L-arginine using bacterium belonging to the genus Escherichia wherein L-amino acid...
7470524 Method for producing L-amino acids using bacteria of the Enterobacteriaceae family  
There is disclosed a method for producing an L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine, L-tryptophan or L-glutamic acid, using a bacterium of the...
7445915 Mutant isopropylmalate isomerase  
The present invention provides a polypeptide comprising an amino acid sequence in which at least one amino acid is deleted, substituted or added in an amino acid sequence of isopropylmalate...
7439036 Process for producing optically active octahydro-1H-indole-2-carboxylic acid  
To provide an enzymatic resolution process for efficiently producing an optically active N-protected-octahydro-1H-indole-2-carboxylic acid denoted by the formula (2): by using an enzyme capable...
7432085 Method for producing L-amino acid  
In a method for producing an L-amino acid by culturing a microorganism having an ability to produce an L-amino acid in a medium to produce and accumulate the L-amino acid in the medium and...
7399618 Method for producing L-histidine using bacteria of Enterobacteriaceae family  
A method is provided for producing L-histidine using bacterium of the Enterobacteriaceae family, wherein the L-amino acid productivity of the bacterium is enhanced by enhancing an activity of the...
7399617 Method for producing an L-amino acid in an Escherichia bacterium via altering expression levels of target proteins  
A bacterium belonging to the genus Escherichia which has an ability to produce an L-amino acid, wherein the ability to produce the L-amino acid is increased by increasing expression of an L-amino...
7311836 Process for producing amino acid or salt thereof by column technique and production apparatus thereof  
According to the process for producing amino acid or salt thereof in the present invention, in the adsorption step, an amino acid-containing aqueous solution is fed into a pressure tight column so...
7300777 Feedback-resistant pyruvate carboxylase gene from corynebacterium  
The present invention relates to a mutated pyruvate carboxylase gene from Corynebacterium . The mutant pyruvate carboxylase gene encodes a pyruvate carboxylase enzyme which is resistant to...
7300776 L-amino acid-producing bacterium and a method for producing L-amino acid  
An L-amino acid-producing strain of Escherichia coli is bred by modifying an Escherichia coli K12 strain or a derivative thereof so as to become resistant to L-valine and have an ability to...
7238501 Process for producing trans-4-hydroxy-L-proline  
The present invention is directed to a process for producing trans-4-hydroxy-L-proline, which is useful as a raw material for medicines or as an additive to foods. In the process, L-proline is...
7160703 Nucleotide sequences coding for the PtsI protein  
The present invention provides nucleotide sequences from Coryneform bacteria which code for the PtsI protein and a process for the fermentative preparation of amino acids using bacteria in which...
7157251 Process for the racemization of N-protected amino acids using racemase  
The present invention relates to the processes of racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected...
7067289 Method for producing histidine by fermentation with E. coli  
The present invention provides a method for producing an amino acid selected from the group consisting of L-alanine, L-valine, L-leucine, L-isoleucine, L-methionine, L-phenylalanine, L-proline,...
6979560 Eschericha bacteria overexpressing the yahn gene for feedback-insensitive amino acid production  
A bacterium belonging to the genus Escherichia and having an ability to produce an L-amino acid, wherein the ability to produce the L-amino acid is increased by increasing an expression amount of...
6953677 Recombinant L-N-carbamoylase from Arthrobacter aurescens and method of producing L-amino acids therewith  
A novel rec-L-N-carbamoylase from Arthrobacter aurescens and its method of use for producing L-amino acids. The recombinantly produced L-carbamoylase is unexpectedly stable, so that an industrial...
6808914 Process for the preparation of L-amino acids by fermentation and nucleotide sequences coding for the accDA gene  
The invention relates to nucleotide sequences coding for the accDA gene and to a process for the preparation of L-amino acids, especially L-lysine, by fermentation using corynebacteria in which the...
6767726 Process for producing cis-3-hydroxy-L-proline  
An isolated gene encodes for a L-proline-3-hydroxylase having the amino acid sequence of SEQ ID NOS: 1, 2, 15, 16 and 17, or for a protein having enzymatic activity to hydroxylate the 3-position of...
6706517 Method for producing L-amino acids by fermentation  
The present invention provides an industrially efficient method for producing an L-amino acid useful as medicament, chemical agent, food material and feed additive, and the method comprising...
6686181 Method for the production of L-amino acids from their racemic N-aceytyl-D, L-derivatives by enzymatic racemate cleavage by means of isolated recombinant enzymes  
Process for the preparation of L -amino acids from their racemic N-acetyl-D,L derivatives by enzymatic resolution by means of isolated, recombinant enzymes A process for the preparation of...
6656710 Process for the production of amino acids using racemase and acylase  
The present invention relates to the processes of racemization and deprotection of special N-protected amino acids in the acylase/racemase system for the total conversion of special N-protected...
6551803 Method for purification of amino acid containing solutions by electrodialysis  
A process is described for purifying an amino acid-containing solution by means of electrodialysis, wherein an amino acid-containing solution is employed which is obtained from the fermentation for...
6365381 Method for producing optically active compound  
The present invention provides a method for industrially advantageously producing (S)-4-hydroxy-2-ketoglutaric acid and for producing compounds which are formed by biosynthesis from the precursor...
6238895 Production of aspartic and malic acids with microbacterium  
The use of strains of the genus Microbacterium for the production of organic acids or amino acids by the enzymatic conversion of a fumaric acid to the organic acid or amino acid desired, as well as...
6204050 Producing diastereomers of 4-hydroxyproline using 4-hp epimerase from Serratia marcescens or Acinetobacter baumanni  
The present invention relates to two novel microorganisms, Acinetobacter baumanni WT-50/50-4A (ATCC 202144) and Serratia marcescens WT-L-4A1(RED) (ATCC 202145) characterized by 4-hydroxyproline...
6171829 Physiologically active substance PF1191 and process for producing the same  
A substance PF1191 having an inhibitory activity to kainic acid toxicity represented by the following formula (I) which is obtained by incubating a fungus belonging to the genus Eupenicillium and...
6143552 Process for producing L-amino acids by fermentation  
The present invention provides a process for producing an L-amino acid which comprises culturing in a nutrient medium a microorganism which is capable of producing the L-amino acid and which can...
6133018 Enzymatic synthesis of chiral amines using -2-amino propane as amine donor  
2-Aminopropane is used as the amine donor in the stereoselective synthesis of a chiral amine from a ketone with a transaminase. In a typical embodiment, (S)-1-methoxy-2-aminopropane is prepared by...
6083917 Methods and compositions for the identification, characterization and inhibition of farnesyltransferase  
Disclosed are methods and compositions for the identification, characterization and inhibition of mammalian protein farnesyltransferases, enzymes involved in the farnesylation of various cellular...
6063615 Enzymatic acylation of amino acid esters using a carboxylic acid ester substituted with oxygen on the alpha carbon  
Disclosed is a process for preparing acylated amino esters and a process for preparing optically active amino esters from racemic amino esters with a carboxylic ester as acylating agent, whose acid...
5928933 Process for the enzymatic resolution of N-(alkoxycarbonyl)-4-ketoproline alkyl esters or N-(alkoxycarbonyl)-4-hydroxyproline alkyl esters using Candida antarctica lipase B  
The present invention relates to a process for the enzymatic resolution of racemic mixtures of N-(alkoxycarbonyl)-4-keto-D,L-proline alkyl esters, using Candida antarctica lipase fraction B (CALB)...
5783427 Process for preparing D-amino acids  
Disclosed is a process for preparing a D-amino acid selected from the group consisting of D-methionine, D-valine, D-leucine, D-isoleucine and D-histidine, which comprises the steps of: making a...
5728555 Preparation of d-amino acids by direct fermentative means  
The present invention relates to materials and methods for production of natural and unnatural D-amino acids. In particular, the present invention relates to a fermentation method for the...
5714355 Microorganism, use thereof and process for the production of L-α-amino acids  
DSM 9771 is a mutant of DSM 7330 which was obtained under selective pressure. Its enzymatic activity is higher by a factor of 2.3 than that of its parent organism. In the presence of an inducer,...
5705370 Process for producing L-amino acids by fermentation  
Culturing an L-amino acid producing microorganism belonging to the genus Brevibacterium or Corynebacterium and having a resistance to a peptide containing glutamic acid or aspartic acid gives...
5693503 Process for preparation of amino acid  
This invention provides a process for preparation of trans-4-hydroxy-L-proline which comprises either culturing Xanthomonas maltophilia NA-62 (FERM BP-4479), Xanthomonas maltophilia JCM No.3807...
5610140 Bradykinin receptor antagonists with neurokinin receptor blocking activity  
The present invention provides a heterodimeric compound possessing bradykinin and neurokinin receptor antagonist activities useful in the treatment of asthma and other inflammatory diseases...
5534506 Use of purpurins, chlorins and purpurin- and chlorin-containing compositions  
The treatment of blood and other body fluids and tissues, the detection of tumors and the treatment of patients is disclosed. The treatment and detection involve the use of families of chlorins,...
5498532 Process for producing amino acids  
The invention relates to coryneform microorganisms capable of assimilating lactose which carry a recombinant DNA capable of conferring the ability to assimilate lactose on coryneform...
5407826 Isolated cultures of microorganisms of Clonostachys Cylindrospora, Gliocladium and Nectria Gliocladioides  
Trans-4-hydroxy-L-proline is produced microbially, especially by the cultivation of a microorganism of the genus Clonostachys, Gliocladium or Nectria.
5374542 Process for producing 4-hydroxy-L-proline  
Disclosed are a process for producing 4-hydroxy-L-proline by the conversion of 4-hydroxy-2-oxoglutaric acid in an aqueous medium in the presence of an amino group donor and an enzyme source...
5364775 Process for producing trans-L-hydroxyproline  
The present invention provides a process for producing trans-L-hydroxyproline, which comprises culturing a microorganism which is capable of decomposing amino acids other than...
5219741 Method of making L-proline using an N-acyl-L-protine acylase  
A microbiologically produced, thermostable N-acylproline-acylase and a process for obtaining it from Comamonas testosteroni DSM 5416 and Alcaligenes denitrificans DSM 5417. The enzyme is useful for...
5216012 Production and use of purpurins, chlorins and purpurin- and chlorin-containing compositions  
Families of chlorins, families of purpurins and metal complexes thereof are disclosed. The purpurins and their metal complexes have the structures of FIGS. 1, 7, 14-18, 29-38, 44-48 and 54-58 of...
5106736 Enzymatic process for enantiomer-specific perparation of mercapto alkanoic acid compounds  
An enzymatic process for the enantiomer-specific preparation of mercapto alkanoic acids by stereoselective hydrolysis of mercapto or thioester alkanoic acid esters.
5071752 Process for the production of L-amino acids  
Process is described for the production of L-amino acids of general formula I ##STR1## in which R 1 means an alkyl radical with at most 12 carbon atoms optionally substituted by hydroxy groups,...
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