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6503739 Processes for producing S,S-2-hydroxypropylenediamine-N-N′-disuccinic acid  
Provided is an industrially advantageous process for producing S,S-2-hydroxypropylenediamine-N,N′-disuccinic acid which does not use expensive optically active substances....
6495314 Process for characterizing proteins  
A protein signature analysis is obtained using a peptide ladder library. The molecular signature of a protein is defined to be that subsequence of amino acid positions within the protein which are...
6432688 Amino alcohol dehydrogenase converts keto alcohol to amino alcohol and amino alcohol to keto alcohol  
A purified amino alcohol dehydrogenase which reductively converts a keto alcohol into an amino alcohol and oxidatively converts an amino alcohol into a keto alcohol is disclosed. The enzyme is...
6432683 Preparation of 2-aminomuconate from 2-aminophenol by coupled enzymatic dioxygenation and dehydrogenation reactions  
A method for the preparation of 2-aminomuconate which comprises adding 2-aminophenol to a mixture of 2-aminophenol 1,6-dioxygenase, 2-aminomuconic semialdehyde dehydrogenase and NAD + ...
6428992 Process for the purification of 1,3-propanediol from a fermentation medium  
The present invention relates to a process for the purification of 1,3-propanediol from a fermentation medium of a 1,3-propanediol-producing microorganism, comprising 1,3-propanediol and...
6379934 Process for the fermentative preparation of L-amino acids using coryneform bacteria  
The invention provides a process for the fermentative preparation of L-amino acids using coryneform bacteria, in which the subunit carrying the biotin-carboxyl carrier protein domain and the...
6379922 Membrane enzyme reactor containing a plurality of biocatalyst-immobilized sheets  
An enzyme membrane reactor is designed to enhance the production efficiency of foods, pharmaceutical products, and other bioproducts. The reactor is formed of a cap and a container in which a...
6372459 N-acetyl amino acid racemase  
The present invention is directed to an N-acetyl amino acid racemase (AAR) as well as the gene coding for it, to a plasmid, vector and microroganism containing the gene. A method of producing...
6365380 Method for stereoselectively inverting a chiral center of a chemical compound using an enzyme and a metal catalyst  
A process for stereoselectively inverting a chiral center of a chemical compound is disclosed. The process first consists of forming a mixture of the chemical comopund, an enzymatic system, and a...
6358714 Materials and methods for the production of D-phenylalanine  
The present invention provides materials and methods for production of D-phenylalanine by recombinant expression in a microorganisms of a D-aminotransferase gene and optionally a dadX gene in...
6355454 Process for the fermentative production of L-amino acids using coryneform bacteria  
This invention relates to a process for the production of L-amino acids using coryneform bacteria, in which the glutamate dehydrogenase gene is amplified.
6352839 Streptogramins for preparing same by mutasynthesis  
The invention provides a method for preparing streptogramins using genetically-modified microorganisms to influence the biosynthesis of at least one of the precursors of the group B streptogramins....
6346402 (S)-α-phenethylamine: pyruvate transaminase  
Relating to an enzyme capable of efficiently converting a ketone compound to an optically active amino compound by transamination, and a process for preparing an optically active amino compound...
6338956 Stress-resistant microorganism and method of producing fermentative product  
A microorganism is utilized to fermentatively produce useful substances such as amino acids by cultivating the microorganism in a medium to allow a fermentative product to be produced and...
6337190 D-amino acid aminotransferase for simultaneously producing glutaryl-7-aminocephalosporanic acid and D-amino acid  
The present invention relates to mutant D-amino acid aminotransferase, including nucleic acids encoding mutant D-amino acid aminotransferase. The mutant D-amino acid aminotransferase of the present...
6335186 Process for the preparation of L-phosphinothricin by a coupled enzymatic reaction  
A coupled enzyme reaction of a transaminase with GOT activity and of a transaminase with L-phosphinothricin transaminase activity produces phosphinothricin in virtually quantitative yield and...
6316232 Microbial preparation of substances from aromatic metabolism/I  
The invention makes available, by means of an increased provision of intracellular metabolic intermediates, in particular of erythrose 4-phosphate, alternative processes for the microbial...
6300105 Methods for producing a succinimide polymer, an aspartic acid polymer and L-aspartic acid  
A succinimide polymer is produced by thermally polymerizing an ammonium salt of aspartic acid in the presence of an acid catalyst such as a boric acid catalyst. Another amino acid may be added for...
6280979 Microbial process for the production of D(-)-N-carbamoylphenylglycine  
A microbial process for the preparation of D(-)-N-carbamoylphenylglycine from DL-5-phenylhydantoin which comprises culturing the strain pseudomonas sp. having Accession No. NCIM 5070 (ATCC 55940)...
6268185 Production of amino acids and enzymes used therefor  
A process for producing α-amino acid from starting material comprising α-amino amide enantiomers (A) and (B) is such that enantiomer (A) is converted preferentially over enantiomer (B) so that a...
6261825 Production of amino acids using auxotrophic mutants of methylotrophic bacillus  
A method of producing amino acids by culturing an amino acid auxotroph of a biologically pure strain of a type I methylotrophic bacterium of the genus Bacillus which exhibits sustained growth at...
6258573 Method of producing L-serine by fermentation  
Disclosed is a coryneform bacterium having resistance to azaserine or β-(2-thienyl)-DL-alanine and having L-serine productivity. Also, disclosed are D-3-phosphoglycerate dehydrogenase derived from...
6248551 Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides  
This invention relates to Helicobacter species aliphatic amidase AmiE polypeptides, the DNA encoding those polypeptides and transformed microorganisms capable of expressing those polypeptides. This...
6245575 Screening of agents for treatment of alzheimer's disease  
A method of screening an agent for potential use in the treatment of Alzheimer's disease, comprises reacting, in the presence of the agent, tau protein with a suitable sulphated carbohydrate under...
6242234 Mutants of formate dehydrogenase from Candida boidinii, new gene sequences encoding these and use of the new formate dehydrogenases  
The invention relates to new mutants of formate dehydrogenase from Candida boidinii, new gene sequences encoding these and use of the new formate dehydrogenases. The wild type FDH used hitherto in...
6238895 Production of aspartic and malic acids with microbacterium  
The use of strains of the genus Microbacterium for the production of organic acids or amino acids by the enzymatic conversion of a fumaric acid to the organic acid or amino acid desired, as well as...
6235506 Process for the fermentative preparation of clavam derivatives whereby the levels of ammonia and urea in the fermentation medium are kept low  
Improved methods for the preparation of clavams by fermentation of a clavam-producing organism in a suitable medium wherein the ammonium levels are kept low so as to avoid repression of enzymes,...
6235516 Biocatalysts with amine acylase activity  
The invention belongs to the field of biotechnology. It concerns a biocatalyst, i.e. a dead or living microorganism or a polypeptide, preferably in isolated form, which exhibits acylase enzymatic...
RE37187 Aminopeptidase GX, and a method of hydrolyzing a protein with the same  
An aminopeptidase is provided which efficiently decomposes a low-molecular-weight peptide containing glutamic acid or aspartic acid in its sequence. A method of hydrolyzing a peptide or protein by...
6214609 Method and apparatus for preparation of chiral beta amino acids using penicilln G acylase  
A method for preparing a chiral beta amino acid or its corresponding esters which comprises contacting a racemic beta amino acid, an acyl donor and Penicillin G acylase enzyme under conditions...
6210934 Gene and gene structure coding for an aminotransferase, and microorganisms which express this gene  
The preparation of L-2-amino-4-methylphosphinobutyric acid (L-PPT) by transamination of (3-carboxy-3-oxo-propyl)-methylphosphinic acid with the aid of the L-PPT-specific transaminase from E. coli...
6197558 Transaminase biotransformation process  
A process for making natural and unnatural amino acids which comprises reacting a first amino acid, a keto acid and a transaminase enzyme under conditions appropriate to produce a second amino acid...
6180374 Method for preparing tert-leucine and analogues thereof in enantiomeric form and intermediates therein  
Azlactone (3), or the opposite enantiomer thereof, undergoes biotransformation, using suitable enzymatic activity, in the presence of a compound YH to form a N-acyl-amino acid (2), wherein R 1 , R...
6174711 Method for producing L-allysine acetal  
A method for producing L-allysine acetal represented by general formula (II), comprising reacting D,L-allysinamide acetal represented by general formula (I) with cells of microorganism or treated...
6146859 Facile synthesis of L-homophenylalanine by equilibrium shift enzymatic reaction using engineered tyrosine aminotransferase  
A process for producing L-homophenylalanine comprises the step of reacting 2-oxo-4-phenylbutyric acid with a L-amino acid in the presence of tyrosine aminotransferase in a reaction solution to...
6143552 Process for producing L-amino acids by fermentation  
The present invention provides a process for producing an L-amino acid which comprises culturing in a nutrient medium a microorganism which is capable of producing the L-amino acid and which can...
6136591 Bioresolution of N-acylazetidine-2-carboxylic acids  
Process for obtaining an enantiomerically enriched N-acylazetidine-2-carboxylic acid, wherein a racemic N-acylazetidine-2-carboxylic acid ester is contacted with an enzyme that displays...
6133018 Enzymatic synthesis of chiral amines using -2-amino propane as amine donor  
2-Aminopropane is used as the amine donor in the stereoselective synthesis of a chiral amine from a ketone with a transaminase. In a typical embodiment, (S)-1-methoxy-2-aminopropane is prepared by...
6133000 Fermentative preparation of amino acids  
A process is disclosed for the fermentative preparation of amino acids, in which an L-lysine producing bacterial strain of the species Corynebacterium glutamicum is cultivated in a nutrient medium...
6121024 Halophilic Pseudomonas strain having accession No.NCIM 5109 (ATCC 55940) and a process for preparingD(-)N-carbamoylphenylglycine using said strain  
The present invention relates to a process for the preparation of D(-)N-carbamoylphenylglycine, by growing Pseudomonas sp deposited at National Collection of Industrial Microorganisms, Pune, India...
6114163 Process for obtaining active L-α-amino carboxylic acids from corresponding racemic d, L-α-amino carboxylic acids  
The disclosure relates to a process for obtaining optically active L-α-aminocarboxylic acids from the corresponding racemic D,L,α-aminocarboxylic acids. The following steps are involved: (a) the...
6103508 Method for removing fumarase activity, microorganisms obtainable by the method, and production of optically active aminopolycarboxylic acids using the microorganisms  
This invention relates to a method for removing fumarase activity from a microorganism or processed product thereof having ethylenediamine-N,N'-disuccinic acid ethylenediamine lyase activity, which...
6083752 DNA coding for decarbamylase improved in thermostability and use thereof  
A DNA fragment coding for a decarbamylase protein improved in thermostability as the result of replacement of at least one base of a DNA fragment coding for a decarbamylase protein derived from a...
6069272 Simplified method for the production of vinyl glycine (2-aminobut-3-enoic acid) and a convenient resolution of a derivative  
The invention relates to a three-step synthesis of vinyl glycine (1) using a cheap, commercially available starting material (3-butenenitrile (2)) and using cheap, simple reagents. Also disclosed...
6068997 Method for the conversion of lecithin into lysolecithin  
Conversion of crude lecithin is performed by incubating the lecithin with a lipase-phospholipase mixture in a water/polyol environment. The incubation is carried out at about 40-50° C. and a pH of...
6063615 Enzymatic acylation of amino acid esters using a carboxylic acid ester substituted with oxygen on the alpha carbon  
Disclosed is a process for preparing acylated amino esters and a process for preparing optically active amino esters from racemic amino esters with a carboxylic ester as acylating agent, whose acid...
6057146 Microorganisms for the stabilization of plasmids  
New microorganisms with plasmids stable relative to betaine use. These new microorganisms contain (a) a hybrid plasmid with a DNA fragment that contains a genetic sequence that codes for the use of...
6025169 Process for production of lysine by fermentation  
The present invention relates to a method for controlling carbon source concentration in the aerobic cultivation of a microorganism. The substrate carbon source remains at a low level in a...
6015704 Mutant aspartase and the preparation thereof  
Disclosed is a mutant aspartase comprising the amino acid sequence of a wild-type E. coli aspartase wherein the amino acid residue at one of positions 25, 123, 421 and 463 is substituted. Also...
6015698 Method of producing D-amino acid and method of producing amine  
D-amino acid with high optical purity represented by formula (1-A) and/or formula (1-B), ##STR1## wherein R represents H or OH, ##STR2## wherein R 1 , R 2 each represents H or OH, and amine...
Matches 201 - 250 out of 435 < 1 2 3 4 5 6 7 8 9 >