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6007839 |
Preparation of pharmaceutical compositions containing etherlipid-containing multiple lipid liposomes
Described herein are methods of preparing liposome-containing pharmaceutical compositions, the liposomes containing headgroup-derivatized lipids and etherlipids having the formula: ##STR1## Such...
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6004666 |
Data carrier having encapsulated scents and a method for producing it
The invention relates to a data carrier (1) having microencapsulated scents and to a method for producing it. The data carrier (1), which is generally made of an unabsorptive material, is in...
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6004534 |
Targeted polymerized liposomes for improved drug delivery
The present invention relates to targeted polymerized liposomes for oral and/or mucosal delivery of vaccines, allergens and therapeutics. In particular, the present invention relates to polymerized...
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6001335 |
Contrasting agents for ultrasonic imaging and methods for preparing the same
Liposomes suitable as ultrasound contrast agents which contain media of various types including gases, gaseous precursors activated by pH, temperature or pressure, as well as other solid or liquid...
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5997946 |
Solid composition
A new and novel solid, microencapsulated product comprising a microencapsulated material contained within a cast, water-soluble, film-forming polymer and the process for preparing such product is...
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5998007 |
Multidirectionally stretch-crazed microencapsulated polymer film and a method of manufacturing thereof
A multidirectionally stretch-crazed microencapsulated polymer film having a matrix material and microcapsules which are formed in the matrix material in the form of crazes which are filled with an...
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5993831 |
Composition providing a lasting cosmetic and/or pharmaceutical treatment of the upper epidermal layers by topical application on the skin
A composition containing, in a suitable carrier, nanoparticles of one or more nonbiodegradable polymer(s) encapsulating an oily phase which contains at least one active oil and/or at least one...
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5989587 |
Formation of stable liposomes from lipid extracts of archaeobacteria (archaeu)
Novel ether lipids were obtained from methanogenic (Methanospirillum hungatei, Methanococcus jannaschii, Methanococcus voltae, Methanosarcina mazei, and Methanobrevibacter smithii), and extremely...
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5985246 |
Contrast agents for ultrasonic imaging and methods for preparing the same
Liposomes suitable as ultrasound contrast agents which contain media of various types including gases, gaseous precursors activated by pH, temperature or pressure, as well as other solid or liquid...
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5980937 |
Liposomes with enhanced entrapment capacity and their use in imaging
The invention relates to a dry deposit as a precursor to liposome vesicles, the precursor being a three dimensional expanded structure with bulk density between 0.01 and 0.001 g/cm 3 . The...
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5976405 |
Method for forming pluralities of droplets and polymer particles having low polydispersity
Disclosed are uniformly sized domains of liquid crystals, a method for forming the domains, and their performance in polymer dispersed liquid crystal displays. The method provides the ability to...
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5976873 |
Nucleic acid sequences controlling lung cell-specific gene expression
An oligonucleotide which includes at least one nucleic acid sequence which binds to at least one nuclear protein found in lung cells, such as TTF-1 protein. The oligonucleotide may be contained in...
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5972508 |
Microcapsules containing bleaching aids
The microcapsules containing bleaching agents are obtainable by polymerizing monomer mixtures which comprise 5-100% by weight of at least one ethylenically unsaturated carboxylic anhydride (a), ...
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5965434 |
Amphipathic PH sensitive compounds and delivery systems for delivering biologically active compounds
The present invention provides amphipathic lipid compounds comprising a hydrophilic, catonic, pH-sensitive moiety, the positive charge of which moiety increases as pH decreases over the pH range of...
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5965109 |
Process for making insoluble gas-filled microspheres containing a liquid hydrophobic barrier
The present invention relates to a process for making insoluble gas-filled, pressure-resistant microspheres containing a liquid or solid hydrophobic barrier within the microsphere shell, and...
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5965158 |
Liposomal-polyene preliposomal powder and method for its preparation
A method is disclosed for preparing a stable preliposomal powder which, when reconstituted with water or saline solution, forms a suspension of liposomes containing a polyene drug, such as...
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5958448 |
Siloxane MQ resin vesicles and entrapment
A method of entrapping a water-soluble substance in vesicles formed from a surface active siloxane is carried out by dissolving the substance to be entrapped in water, adding the surface active...
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5958589 |
Starch-based microcellular foams
Starch-based microcellular foams composed of a solid matrix with a network of small open cells or pores are described. The foams have high pore volume, low density, and high surface area, and are...
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5954864 |
Furniture polish
A furniture polish including a conventional active polishing ingredient is provided with a fragrance micro-encapsulated in a plurality of naturally self-adhesive microcapsules of varying wall...
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5948441 |
Method for size separation of particles
Tangential flow filtration is used in the size separation of particles, such as liposomes and lipid particles. These particles may be passed through a tangential flow filtration device of any pore...
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5935599 |
Polymer-associated liposomes for drug delivery and method of manufacturing the same
Novel polymer-associated liposomes (PALs) containing a liposome, and a polymer having a plurality of acid moieties, like sulfonic acid moieties, carboxyl moieties, or phosphonic acid moieties, in a...
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5925464 |
Microencapsulation process and product
Microencapsulated compositions, useful, for example, as pesticidal formulations, were prepared a process in which the microcapsules containing the encapsulated material are formed in an interfacial...
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5919407 |
Method for producing microencapsulated adhesive
A microencapsulated adhesive and a method for producing that microencapsulated adhesive are disclosed. The adhesive is produced from a solvent-based adhesive composition such as a styrene butadiene...
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5908697 |
Active principle carriers containing non-ionic surfactants, and uses thereof, particularly in food, cosmetics and pharmaceuticals
Novel active principle carriers containing non-ionic surfactants are disclosed. The surfactants mainly consist of sucrose and fatty acid esters and form onion-structured microcapsules within which...
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5906831 |
Controlled release composition forming a reversed micellar (L2) structure or a normal micellar (L1) structure
A controlled-release composition for a biologically active material, characterized in that it comprises a mixture of: a) monocaproin, optionally in admixture with moncaprylin and/or monocaprin, and...
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5895661 |
Liposome vesicle precursors
The invention relates to a dry deposit as a precursor to liposome vesicles, the precursor being a three dimensional expanded structure with bulk density between 0.01 and 0.001 g/cm 3 . The...
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5885671 |
Polyoxyalkylene glycol gelatin capsule fill formulations comprising crosslinked carboxylic copolymers
Disclosed are fill compositions suitable for carrying pigment and encapsulation within gelatin capsules comprising: (a) a polyoxyalkylene glycol having a mean molecular weight of from about...
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5885491 |
Method to increase the stability of nanocapsules during storage thereof
Methods of increasing storage stability of lipidic nucleus nanocapsules comprising adding a monosaccharide cryoprotective agent into the aqueous dispersion of the nanocapsules while maintaining...
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5885613 |
Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
The present invention provides a fusogenic liposome comprising a lipid capable of adopting a non-lamellar phase, yet capable of assuming a bilayer structure in the presence of a bilayer stabilizing...
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5866158 |
Composition composed of an aqueous dispersion of stabilized vesicles of nonionic amphiphilic lipids
The vesicles are prepared from a lipid phase containing a mixture of nonionic amphiphilic lipids consisting of a mixture of esters of at least one polyol chosen from the group composed of...
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5861214 |
Thermoexpandable microcapsule and production
The object of the present invention is to provide a thermoexpandable microcapsule which can be expanded at a lower temperature without decrease of various properties such as chemical resistance and...
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5858487 |
Non-stick microwaveable food wrap
According to the present invention a non-stick, microwaveable food wrap for crispening and browning of food is provided comprising a non-stick layer; a polymeric film layer; an unperforated...
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5853755 |
Biphasic multilamellar lipid vesicles
A biphasic multilamellar lipid vesicle comprising a plurality of spaced apart lipid bilayers that include a liposome-forming component and optionally a biologically active agent entrapped within...
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5849412 |
Encapsulated materials
Methods and compositions for encapsulated polymeric gels swollen with nonaqueous reactive materials are provided. The methods include gel synthesis, swelling of a gel precursor with a first...
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5846762 |
Structurally stable gel bead containing entrapped enzyme and method for manufacture thereof
A structurally stable gel bead containing an entrapped enzyme and a method for its manufacture. The enzyme is covalently cross-linked to gelatin in the presence of glutaraldehyde prior to the...
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5846561 |
Method of binding collagen recognizing substances to liposomes
Recognizing substances, including epidermal growth factor, gelatin, collagen and hyaluronic acid, have been covalently bound to liposomal surfaces and utilized to attach liposomes onto a cellular...
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5827924 |
Polymer sealant microencapsulated by polyurethane reaction and its binder solution
This invention relates to polymer sealant microencapsulated by polyurethane reaction and its binder solution, particularly employing threaded mechanical fasteners such as bolt-nuts, screws, pipe...
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5804216 |
Acidic composition based on lipid vesicles and its use in topical application
A composition containing a dispersion of lipid vesicles with an aqueous core and/or of lipid vesicles with an oily core. At least one acidic compound is present in the dispersion in an amount which...
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5804297 |
Thermal insulating coating employing microencapsulated phase change material and method
A method of insulating a substrate from repeated thermal transients and/or thermal impulses applied thereto by proximately absorbing and storing the thermal transients and/or thermal impulses for...
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5804298 |
Microcapsules with reduced shell wall permeability
Incorporation of inorganic colloidal particles into an encapsulation dispersion results in microcapsules having polymer shell walls further comprising colloidal inorganic particles. Capsules...
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5795570 |
Method of containing core material in microcapsules
A core material such as animal tissue or cells is contained within a semipermeable vessel which may be a microcapsule, hollow fiber or plastic membrane having a semipermeable wall by a method that...
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5795589 |
Liposomal antineoplastic agent compositions
A method for encapsulation of antineoplastic agents in liposomes is provided, having preferably a high drug:lipid ratio. Liposomes may be made by a process that loads the drug by an active...
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5792472 |
Process for the preparation of microcapsules or liposomes of controlled sizes
Process for the preparation of microcapsules with controlled sizes in which a homogeneous liquid crystal lamellar phase is prepared comprising at least one surfactant and at least one solvent and,...
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5780060 |
Microcapsules with a wall of crosslinked plant polyphenols and compositions containing them
Microcapsules based on crosslinked plant polyphenols are described. These microcapsules are obtained by the interfacial crosslinking of plant polyphenols, particularly flavonoids. When incorporated...
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5776490 |
Complex protein-walled microcapsules containing lipid-walled microcapsules and method for producing same
Complex protein walled microcapsules (40) incorporate lipid-walled microcapsules (48) that include constituents to be retained in the presence of hydration such as water soluble vitamins and...
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5773024 |
Container with multi-phase composition for use in diagnostic and therapeutic applications
A container comprising an aqueous lipid suspension and a gaseous phase substantially separate from the aqueous stabilizing phase, useful in diagnostic imaging such as ultrasound and magnetic...
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5766520 |
Preservation by foam formation
A method of preserving sensitive biological dispersions, suspensions, emulsions and solutions by forming stable foams from fluid materials to be dehydrated, as an aid both to the drying of one or...
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5762904 |
Oral delivery of vaccines using polymerized liposomes
Polymerized liposomes, methods of preparing the polymerized liposomes and incorporating biologically active substances within the polymerized liposomes, and methods of administering polymerized...
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5762958 |
Multilipid component ether lipid liposomes
Liposomes are provided which contain ether lipids having the formula: ##STR1## as well as an underivatized phosphatidylethanolamine, a sterol, and a phosphatidylethanolamine-dicarboxylic acid...
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5759582 |
Controlled release of pharmaceutically active substances from coacervate microcapsules
A controlled-release pharmaceutical composition comprising a pharmaceutically active water soluble protein, peptide, glycoprotein, or mixture thereof, encapsulated in the form of microspheres by a...
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