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5132117 Aqueous core microcapsules and method for their preparation  
A microcapsule comprising an aqueous core, and capsular membrane formed from the interfacial reaction product of a hydrophilic polymeric Lewis acid or salt thereof with a lipophilic Lewis base or...
5126061 Microcapsules containing hydrophobic liquid core  
Microcapsules which are prepared using coacervation processes and/or which have a complex structure in which there is a large central core of encapsulated material, preferably perfume, and the...
5120360 Microcapsule-containing ink composition for flexographic printing  
A microcapsule-containing ink composition for flexographic printing containing microcapsules, an adhesive and an ink medium, the composition being characterized in that the adhesive includes a...
5118590 Light-sensitive microcapsule containing polymerizable compound and pigment particles  
A light-sensitive microcapsule contains silver halide, an ethylenically unsaturated polymerizable compound and pigment particles. Another light-sensitive microcapsule contains a photopolymerization...
5118528 Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles  
The process according to the invention comprises: (1) the preparation of a liquid phase consisting essentially of a solution of the substance in a solvent or in a mixture of solvents to which may...
5108759 Endothelial envelopment drug carriers  
This application describes the preparation and in vivo testing of surface coatings and matrix materials, which when applied to or caused to comprise the carriers for drugs and diagnostic agents,...
5106624 Method for an effective moisturizing treatment of the skin, particularly useful in cosmetics applications  
A method and product for moisturizing the human skin which comprises topically applying to the skin a composition comprising liposomes and mineral water.
5104736 Reinforced paucilamellar lipid vesicles  
Disclosed are paucilamellar lipid vesicles reinforced with polyacrylamide, and methods of producing the same. The vesicles include about 2-10 lipid bilayers in the form of substantially spherical...
5104661 Reverse loading of liposomes  
The first part explains the discovery, and means to employ the discovery that whole, intact vesicles and liposomes are not the sole means of burden (drug) delivery by targeting molecules. The...
5100662 Steroidal liposomes exhibiting enhanced stability  
The present invention relates to novel liposomes and liposome-like structures (vesicles) comprising an amount of a derivatized sterol either alone or in combination with additional liposome-forming...
5094854 Liposome composition useful for hypertheria therapy  
This invention relates to the liposome compositions which are characterized in that the phase transition temperature of the membrane is in the range of 40° to 45° C. and the osmotic pressure of a...
5093200 Multilayer sustained release granule  
A multilayer granule of the invention comprises a core, a slow-release layer, a rapid-release layer to be provided outer of said slow-release layer and a film layer containing a metal stearate and...
5084350 Method for encapsulating biologically active material including cells  
Method for encapsulating biologically active material within a semipermeable capsule wherein gelled beads are obtained by suspending the material in a solution of a water-soluble substance which...
5071707 Microcapsule for use in making carbonless transfer paper  
Microcapsules containing a color-forming material and a solvent therefor, the solvent being a mixture of certain oligomeric isomers of benzylcumene and its higher homologues and a mixture of...
5071706 Oily, free-flowing, microcapsules  
This disclosure is directed to the preparation of oily microcapsules which can be easily tray dried to a free flowing product without requiring special drying equipment. These microcapsules have a...
5069936 Manufacturing protein microspheres  
Processes for producing biocompatible and biodegradable protein microspheres with controlled porosity and microsphere sizes are disclosed. Generally, the processes are accomplished as follows: (a)...
5064470 High solids, low viscosity carbonless paper gelatin base microcapsule system  
This disclosure is directed to a high solid, low viscosity carbonless paper gelatin base microcapsule system producing microcapsules having sizes characteristically from about 3 to about 10 microns...
5064655 Liposome gel composition and method  
A liposome gel composition and method of preparing the same. The composition is composed of charged liposomes, at a relatively low lipid concentration, in a low-conductivity medium. The composition...
5061492 Prolonged release microcapsule of a water-soluble drug  
A microcapsule produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing said water-soluble drug and a drug retaining substance therefor and an oil layer containing...
5055373 Multicolor recording material  
A multicolor recording material is disclosed, which comprises a support having provided thereon a coating layer comprising two or more kinds of microcapsules each containing at least a leuco dye...
5055390 Process for chemical manipulation of non-aqueous surrounded microdroplets  
A process for the chemical manipulation of liquid and gel microdroplets is disclosed. The process involves providing first microdroplets having aqueous interiors, such that the first microdroplets...
5053277 Microcapsules and their production  
The present invention comprises a pressure-sensitive chromogenic copy system comprising a transfer sheet having on at least a portion of at least one surface thereof a coating of microcapsules...
5051304 Microcapsules based on gelatin and polysaccharides and process for obtaining same  
This invention relates to microcapsules based on gelatin and anionic polysaccharides of low molecular weight which may contain solid or liquid matters, prepared by coacervation. The aqueous...
5051305 Stabilized perfume-containing microcapsules and method of preparing the same  
Rupturable microcapsules made up of very small droplets or globules of perfume oil encapsulated with an inert polymeric wall are stabilized by providing ethyl cellulose in the perfume oil. This...
5049322 Process for the preparaton of dispersible colloidal systems of a substance in the form of nanocapsules  
The process according to the invention comprises: (1) the preparation of a liquid phase consisting essentially of a solution of a substance A in a solvent or in a mixture of solvents, and...
5049388 Small particle aerosol liposome and liposome-drug combinations for medical use  
Disclosed are aqueous aerosol droplets containing liposome or interacted liposome-drug or medication combination particles in a continuous phase of air or oxygen-enriched air advantageous for the...
5043107 Preparation small unilamellar vesicles including polyene antifungal antibiotics  
Formulations consisting of phospholipid small unilamellar particles encapsulating polyene antifungal antibiotics and methods for using such compositions to treat systemic fungal infections are...
5043164 Blood-stable, cholesterol-free liposomes  
Small unilamellar liposomes (d<600 nm) comprising an unsaturated phosphatidylethanolamine (PE) such as dioleoyl PE (DOPE) and a fatty acid such as oleic acid (OA) are stabilized by adding to a...
5041278 Alpha tocopherol-based vesicles  
Methods and compositions are described for the preparation of alpha-tocopherol vesicles, the bilayers of which comprise a salt form of an organic acid derivative of alpha-tocopherol such as the...
5037698 Capsule filling employing hygroscopic components  
Capsules containing a hygroscopic or deliquescent component are stabilized by a) forming a mixture of the hydrogscopic or deliquescent compound with a sufficient quantity of water to achieve an...
5035844 Process for the production of microcapsules  
In a process for the production of microcapsules by coavervation of gelatin, carboxymethyl cellulose (CMC) and a second anionic polymer such as a polyvinylmethylether/maleic anhydride copolymer or...
5034217 Cosmetic makeup compositions containing crosslinked poly β-alanine microspheres impregnated with polyhydric alcohol  
An anhydrous cosmetic makeup composition for the lips and skin contains crosslinked poly β-alanine microspheres impregnated with a polyhydric alcohol.
5032457 Paucilamellar lipid vesicles using charge-localized, single chain, nonphospholipid surfactants  
Disclosed are paucilamellar lipid vesicles made of single chain nonphospholipid anionic or zwitterionic surfactants and a method of their manufacture. The preferred vesicle forming materials are...
5030442 Non-crystalline minoxidil composition  
An aqueous, noncrystalline minoxidil composition for topical use which has significantly improved flux of the drug through human cadaver skin. The composition contains minoxidil complexed with an...
5030539 Developer sheet useful in providing transparencies or reproductions having a controlled gloss finish utilizing a surfactant  
Disclosed is a developer sheet useful in forming reproductions having a glossy finish, or in forming transparencies comprising: a support having a layer of a finely divided, thermoplastic,...
5023086 Encapsulated ionophore growth factors  
Encapsulated ionophore growth factors and methods of encapsulating these growth factors in lipid vesicles, particularly nonphospholipid paucilamellar lipid vesicles, have been discovered. These...
5021200 Process for the production of aqueous dispersions of lipid spheres  
A process for producing a dispersion of spherules of a lipid compound encapsulating an aqueous phase includes admixing a water-dispersible lipid compound with an aqueous phase to be encapsulated in...
5019369 Method of targeting tumors in humans  
A method is provided for delivering micellular particles containing a radiolabelled marker to tumors within humans. The micellular particles are less than approximately 2000Å and incorporate...
5019392 Encapsulation of parasiticides  
The present invention relates to encapsulated parasiticides, a method for their production, and methods of treatment to prevent or eradicate infestation using the encapsulated parasiticides. The...
5019174 Removing oil from surfaces with liposomal cleaner  
The present invention concerns a lipid vesicle skin cleaner which is exceptionally effective at removing oily dirt from hands or the face. The same type of cleaner can also be used to remove dirt...
5019394 Liposome composition and its production  
The liposome compositions entrapping a drug are prepared by constituting the liposomal membrane with saturated phospholipids and anionic surfactants of high Krafft point at concentrations above...
5017359 Aerosol compositions for in vivo imaging and therapy  
The present invention relates to an aerosol composition for in vivo imaging or ex vivo diagnosis of tumors, which composition contains one or more soluble fragments of bacterial wall or cell...
5017225 Microencapsulated photochromic material, process for its preparation and a water-base ink composition prepared therefrom  
This invention relates to a microencapsulated photochromic material and a process for its preparation. More particularly, it relates to a microencapsulated photochromic material having a good...
5013473 Encapsulated cosmetic materials and process of making  
The use of frangible microcapsules in cleansing creams and cold creams and other cosmetic products improves their cleansing, cleaning, and removal properties without damage to the skin.
5008288 Carnitine directed pharmaceutical agents  
Carnitine, aminocarnitine and cysteic acid serve as carriers to bring pharmaceutically active compounds to desired sites in the body, e.g. skeletal muscle or the heart. The pharmaceutically active...
5008050 Extrusion technique for producing unilamellar vesicles  
A method for reducing the lamellarity of a population of liposomes is provided which comprises repeatedly passing the liposomes under pressure through a filter which has a pore size equal to or...
5008109 Vesicle stabilization  
The present invention relates to a process of stabilizing micellular particles such as vesicles and increasing the shelf life by suspending the particles in a polymeric gel matrix. The invention...
5000960 Protein coupling to lipid vesicles  
A new method of coupling proteins and other targeting molecules to lipid vesicles has been developed. A bifunctional agent forms a covalent bond without damaging the lipid structure and permits...
4997599 Preparation of water soluble cellulose acetate microspheres  
Microparticle of cellulose acetate and derivatives thereof characterized by being water soluble, having a large interior void space and having a plurality of open exterior surface pores. These...
4996104 Temperature-sensitive materials and devices  
A device for indicating whether a rise in temperature above a predetermined value has occurred includes a support member, such as a label, on which a temperature-sensitive material is deposited....