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7390526 |
Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon
Biocompatible composites comprising peptide amphiphiles and surface modified substrates and related methods for attachment thereon.
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7351433 |
Method for producing polymeric sol of calcium phosphate compound and method for coating the same on a metal implant
Disclosed is a method for producing a transparent and homogenized polymeric sol of a calcium phosphate compound, containing apatite and having excellent wettability and bioactivity, according to a...
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7344749 |
Method for coating a substrate with calcium phosphate
A method for coating substrates with calcium phosphate. The aim of the method is to be able to carry out a simple coating for all materials as well as for particles. To this end, the substrate to...
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7285304 |
Fluid treatment of a polymeric coating on an implantable medical device
A method of manufacturing an implantable medical device including applying a composition to an implantable medical device, the composition including a polymer, an active agent and a solvent;...
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7247288 |
Method of manufacturing hydroxyapatite and uses therefor in delivery of nucleic acids
Provided is a method for production of nanocrystalline hydroxyapatite particles, and nanocrystalline hydroxyapatite particles produced according to the method. The nanocrystalline hydroxyapatite...
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6994883 |
Method for applying a bioactive coating on a medical device
The invention relates to the field of medical devices. More in particular, the invention relates to a method for coating by depositing inorganic ions and a bioactive agent to provide sterile...
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6977095 |
Process for producing rigid reticulated articles
A process for producing a rigid reticulated article involves coating a reticulated substrate which has open, interconnected porosity with a first dispersion comprising a ceramic or metal powder to...
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6905723 |
Strontium-substituted apatite coating
The invention provides a method of preparing an implantable article with a bioactive strontium-substituted ceramic apatite coating. The method involves incubating a biocompatible substrate surface...
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6821528 |
Antibiotic calcium phosphate coating
A process for applying a coating having a therapeutic agent such as an antibiotic or a bone morphogenic protein to an implant uses the high surface area of a calcium phosphate coated metal implant...
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6803069 |
Method for imparting a bio-active coating
Disclosed are implantable medical devices with enhanced patency. Expanded polytetrafluoroethylene small caliber vascular grafts coated with polymer bound bio-active agents that exhibit enhanced...
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6787179 |
Sterilization of bioactive coatings
The invention provides a method for single-step surface modification, grafting and sterilization for bio-active coating on materials and biomaterials used in medical devices, such as catheters,...
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6733503 |
Method for coating medical implants
The present invention relates to a method for coating a medical implant, wherein the implant is submersed in an aqueous solution of magnesium, calcium and phosphate ions through which a gaseous...
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6720023 |
Method for preparation of the supersaturated solution of calcium phosphate and the thin film of calcium phosphate crystal by using the solution
The present invention relates to a method for preparation of the supersaturated calcium and phosphate ions solution and a method for preparation of the thin film of calcium phosphate crystal on...
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6709694 |
Coloring ceramics by way of ionic or complex-containing solutions
The invention relates to the coloring of ceramics by means of ionic or complex-containing solutions. Solutions preferred for this contain defined concentrations of at least one of the salts or...
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6706654 |
Pressable glass ceramic, method for the fabrication thereof, and method for the fabrication of a dental restoration using such glass ceramic
A pressable glass ceramic which contains lithium silicate glass and leucite is disclosed. Also, disclosed is the combination of leucite and a lithium silicate glass to stably increase the...
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6692790 |
Proteinaceous coating
The invention relates to a method for providing a proteinaceous coating on a medical implant, comprising the steps of: submersing the implant in a first aqueous solution comprising a protein and...
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6685987 |
Enhanced fatigue strength orthopaedic implant with porous coating and method of making same
A method for producing an orthopaedic implant having enhanced fatigue strength. A forged implant substrate having an elongated stem is incorporated with a melting point lowering substance. Then,...
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6635305 |
Process for coating a siliceous substrate with a silicon containing layer
A process for coating at least a portion of a face of a siliceous substrate with a silicon containing layer, the process includes at least the following steps: a treatment step, in which at least...
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6589590 |
Composite material and methods of making the same
A method of making artificial bone comprises providing a membrane of collagen with solutions of calcium ions and of phosphate ions on opposite sides of the membrane. The calcium ions and phosphate...
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6589365 |
Method of forming an oxide film on a metallic member
A hydrogen peroxide solution is applied onto the surface of a metallic member to oxidize the metallic member and to form the oxide film. At this time, a light beam is irradiated towards the...
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6569489 |
Bioactive ceramic coating and method
A bioactive bone mineral carbonated nano-crystalline apatite is chemically bonded to a variety of substrates, including implantable prostheses. This coating is applied uniformly to substrate...
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6569292 |
Method and device for forming a calcium phosphate film on a substrate
A method of forming thin porous layers of calcium phosphate upon a silicon wafer surface using a high voltage spark. The outer layer of calcium phosphate is the inorganic component of bone and is...
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6534197 |
Biomedical implant material and method of producing the same
The present invention provides a biomedical implant material comprising a substrate for biomedical implant made of a ceramic material, a first coating layer formed on the surface of said substrate...
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6534112 |
Semi-automatic coating system methods for coating medical devices
A semi-automated coating system for providing medical devices with antimicrobial coatings is disclosed. The semi-automated coating system extends the coating solution's usable life span by...
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6521264 |
Method for preparing a biomaterial based on hydroxyapatite, resulting biomaterial and surgical or dental use
A solid powder product with a Ca/P ratio of between 1.40 and 1.90 is prepared from tricalcium phosphate and tetracalcium phosphate. An aqueous solution containing calcium ions and phosphate ions...
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6451059 |
Viscous suspension spinning process for producing resorbable ceramic fibers and scaffolds
The present invention provides a hard tissue scaffold comprising a resorbable ceramic. The scaffold is formed by first creating unfired (green) bioresorbable ceramic fibers via the viscous...
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6426114 |
Sol-gel calcium phosphate ceramic coatings and method of making same
This invention relates to novel sol-gel calcium phosphate, in particular hydroxyapatite ceramic coatings and processes of making same at low temperature. Such coatings are useful, inter alia, for...
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RE37718 |
Ion beam modification of bioactive ceramics to accelerate biointegration of said ceramics
The present invention provides for faster and stronger tissue-implant bonding by treating a ceramic implant with an ion beam to modify the surface of the ceramic. The surface modification can give...
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6344061 |
Device for incorporation and release of biologically active agents
The invention provides an implantable device coated with a layer of calcium phosphate and optionally one or more biologically active substances such as growth factors, lipis, (lipo)polysaccharides,...
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6339913 |
Method for improving the osteointegration of osseus fixing implants
The osteointegration of osseous fixing implants may be improved through a series of surface treatments. These treatments comprise a cleaning and passivation process, the application of a coating of...
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6338810 |
Method for making apatite ceramics, in particular for biological use
A process for manufacturing an apatite ceramic, especially for biological use involves the preparation of a homogeneous mixture of powders to form a hydroxyapatite of formula Ca 10 (PO 4 ) 6 (OH) 2...
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6306784 |
Alkali silicate glass
Alkali silicate glasses are described which, in view of their good chemical stability and their optical properties and processing properties, are particularly suitable as a coating or veneering...
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6280789 |
Process for preparation of hydroxyapatite coatings
Coatings of scarcely crystalline carbonated hydroxyapatite are deposited on metallic or ceramic substrates, by immersing the substrates in a solution containing calcium phosphate and bicarbonate...
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6248392 |
Method for manufacturing a fiber-reinforced bioactive ceramic implant
The invention relates to a method for manufacturing a fiber-reinforced bioactive ceramic implant, wherein a base form is made from fibrous material and interspaces between the different fibers are...
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6206958 |
Dental porcelain compositions
Porcelain compositions of the present invention comprises particulate of one or more glass or glass-ceramic powder components. Additionally, one or more opacifing agents, pigments, fluorescing...
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6206957 |
Tricalcium phosphate-containing biocement pastes comprising cohesion promoters
The invention relates to biocement pastes based on tricalcium phosphate and materials which are suitable for preventing or reducing the tendencies of the settable pastes to disintegrate and for...
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6159417 |
Method for fabricating ceramic network material
A process for producing a ceramic network material including the steps of: introducing a ceramic powder into a mold to form a molded material; firing the molded material to form a ceramic, open...
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6153266 |
Method for producing calcium phosphate coating film
The present invention provides a method for producing a calcium phosphate coating film on the surface of a substrate, even a substrate which has poor heat resistance. The method comprises the steps...
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6146686 |
Implant material and process for using it
The invention provides a nanotechnology process for implant surface treatment for producing an implant article. The nanotechnology process comprises subjecting a non-porous material to a mechanical...
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6143354 |
One-step method for attachment of biomolecules to substrate surfaces
A method of modifying the surface characteristics of a substrate, particularly a polymeric material. The method involves grafting ethylenically unsaturated monomers and attaching biomolecules, such...
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6136029 |
Bone substitute materials
A strong, porous article useful as a bone substitute material and having an outer surface defining a shape having a bulk volume and having open interconnecting interstices extending throughout said...
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6129928 |
Biomimetic calcium phosphate implant coatings and methods for making the same
This invention encompasses porous, nanocrystalline, biomimetic calcium phosphate coatings of the order of 2-30 microns that can be grown on metal implants. The chemical surface treatments and...
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6113993 |
Method of coating a substrate with a calcium phosphate compound
The present invention is a method of coating a substrate with a calcium phosphate compound using plasma enhanced MOCVD. The substrate is a solid material that may be porous or non-porous, including...
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6057031 |
Plastic substrate with thin metal-containing layer
The invention relates to a composite composed of a plastic substrate and a thin, continuous metal-containing layer, characterised in that the metal-containing layer is ductile, adheres firmly to...
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6051272 |
Method for synthesizing organoapatites on to surgical metal alloys
The present invention provides a method for growing or depositing artificial bone materials called organoapatites on a metal surgical alloy. The method involves pretreating the alloy with at least...
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RE36573 |
Method for producing thick ceramic films by a sol gel coating process
A method for producing thick ceramic films of greater than 10 μm on selected substrates is described. Conventional sol gel solutions are loaded with up to about 90% by weight of finely divided...
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6013591 |
Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production
Methods for synthesis of nanocrystalline apatites are presented, as well as a series of specific reaction parameters that can be adjusted to tailor, in specific ways, properties in the recovered...
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5980974 |
Coated orthopaedic implant components
An improved coated orthopaedic implant component is disclosed. The implant may be coated with platinum, iridium or other metals for improved characteristics. Ion beam coating orthopaedic parts by...
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5958504 |
Hydroxyapatite coatings and a method of their manufacture
A process for the production of a hydroxyapatite coated article includes contacting a coating comprising hydroxyapatite with a recrystallization medium, pressurizing the recrystallization medium,...
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5855950 |
Method for growing an alumina surface on orthopaedic implant components
A method is disclosed for ion beam treating orthopaedic parts by ion implanting the parts with aluminum ions while the parts are immersed in an oxygen-containing background gas. When the parts are...
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