Matches 301 - 350 out of 453 < 1 2 3 4 5 6 7 8 9 10 >
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5939208 Method for creation of biomimetic surfaces  
In the present invention method, the surface of articles made of acrylic polymers and methacrylic polymers are converted into thin biomimetic layers by using the process involving at least the...
5910518 Oxygen permeable contact lens having high durable hydrophilic surface and method for producing the same  
A hydrophilic oxygen permeable contact lens having a front surface which is not to be in contact with the cornea of a human eye when the contact lens is worn on the human eye, wherein at least the...
5900246 Drug incorporating and releasing polymeric coating for bioprosthesis  
In accordance with the present invention, there are provided prosthetic articles having polyurethane coatings with biologically active compounds incorporated within the interstices of the polymer....
5891506 Oxidative method for attachment of glycoproteins or glycopeptides to surfaces of medical devices  
A method for making a medical device having at least one glycoprotein and/or glycopeptide immobilized on a substrate surface is provided. The method may include oxidizing 1,2 dihydroxy moieties...
5891196 Method for actively binding heparin to crosslinked biological tissues  
Methods for binding heparin to biological or synthetic materials which are to be implanted within a mammalian body. In instances where connective tissue proteins or other components of the material...
5885647 Coating process  
A process for coating of an intraocular lens to impart tissue compatibility thereto, comprising the steps: a) priming said lens using a solution of a polyamine; b) coating the lens treated in step...
5866113 Medical device with biomolecule-coated surface graft matrix  
A medical device having a surface graft matrix comprising carboxyl-functional groups located on the device, the surface graft matrix comprising an outer portion; and one or more biomolecules...
5855618 Polyurethanes grafted with polyethylene oxide chains containing covalently bonded heparin  
Disclosed are bio-active polymer coatings. More particularly, improved bio-active polymer coating are disclosed which include bio-active molecules attached to polyurethane backbones via...
5834051 Intramuscular stimulation lead with enhanced infection resistance  
To minimize the incidence and consequences of device related infection that occur after prosthetics implants of neuro-muscular stimulating devices, an infection resistant intra-muscular lead has...
5830539 Methods for functionalizing and coating substrates and devices made according to the methods  
Methods for coating substrates are described. The methods comprise coating at least a portion of a substrate with particular coating materials. The coating materials can be crosslinked and coated...
5824056 Implantable medical device formed from a refractory metal having a thin coating disposed thereon  
An implantable medical device formed from a drawn refractory metal and having an improved biocompatible surface is described. The method by which the device is made includes coating a refractory...
5811151 Method of modifying the surface of a medical device  
A medical device having a surface graft matrix comprising carboxyl-functional groups located on the device, the surface graft matrix comprising an outer portion; and one or more biomolecules...
5804263 Combined plasma and gamma radiation polymerization method for modifying surfaces  
A material consisting of a hydrophobic material having a metallic, ceramic or glass surface which has been modified by exposing the surface to a glow discharge plasma to activate the surface,...
5804318 Lubricious hydrogel surface modification  
New and improved lubrifying coatings for reducing the coefficients of friction of surfaces on medical devices include hydrophilic copolymers derived monoethylenically-unsaturated monomers including...
5789461 Methods of forming an extended wear ophthalmic lens having a hydrophilic surface  
An ophthalmic lens suited for extended-wear for periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The...
5788979 Biodegradable coating with inhibitory properties for application to biocompatible materials  
A method is disclosed for coating a biomaterial to be placed in contact with a patient's blood flow to inhibit blood coagulation from adhering to the biomaterial that would otherwise result from...
5782908 Biocompatible medical article and method  
A medical article having a metal or glass surface with the surface having an adherent coating of improved biocompatibility. The coating is made by first applying to the surface an silane compound...
5756145 Durable, Resilient and effective antimicrobial coating for medical devices and method of coating therefor  
A medical implant, such as an orthopedic implant, having a first antimicrobial coating layer and a second protective layer, and a method for coating such an implant is provided. The medical implant...
5744515 Method and implantable article for promoting endothelialization  
A porous material with an appropriate surface chemistry that promotes capillary endothelialization is disclosed. The material has a porosity that is sufficient to allow capillary endothelialization...
5728420 Oxidative method for attachment of glycoproteins to surfaces of medical devices  
A method for making a medical device having a glycoprotein immobilized on a substrate surface is provided. The method includes oxidizing 1,2 dihydroxy moieties with a periodate to form an...
5725573 Medical implants made of metal alloys bearing cohesive diamond like carbon coatings  
The present invention provides a method for coating a metal alloy component of a medical implant, particularly a component of a heart valve made of a titanium base alloy, with a strongly adhered...
5716406 Method of reducing medical device related infections  
The growth of microorganisms on catheters and other medical devices is inhibited by slime-inhibiting compounds. Slime-inhibiting compounds include salicylic acid and other NSAID.
5716660 Tubular polytetrafluoroethylene implantable prostheses  
An implantable prosthesis comprising an expanded polytetraethylene member having pores present in its wall structure wherein said pores contain a solid insoluble biocompatible, biodegradable...
5712327 Soft gas permeable contact lens having improved clinical performance  
A hydrophilic soft gas permeable contact lens having substantially improved clinical performance by the provision of a sufficient higher proportion of hydroxy acrylic units to silicon units in the...
5693098 Fibrin D-domain multimer prostheses and methods for their production  
Methods for coating a prosthetic surface with anti-thrombogenic, or anti-coagulant, proteins are disclosed. The methods involve contacting a surface of a prosthetic material with a composition...
5679400 Intravascular stent and method  
A method for making an intravascular stent by applying to the body of a stent a solution which includes a solvent, a polymer dissolved in the solvent and a therapeutic substance dispersed in the...
5668193 Solid substrate coated with an aminopolysaccharide  
A solid substrate, the surface of which has been modified to introduce reactive groups of a hydrophilic nature thereon, the modification being provided by a primer comprising a first polysaccharide...
5660873 Coating intraluminal stents  
A method is provided for forming fibrin coatings on a substrate, such as device for implantation in a body. The fibrin coatings are dried to provide a fibrin coating having the ability to be stored...
5654030 Method of making implantable stimulation electrodes  
The invention relates to methods of making an improved stimulation electrode for cardiac pacing and defibrillating. Specifically, the electrodes of the invention by virtue of the methods of...
5645882 Cross-linked polyethylene oxide coatings to improve the biocompatibility of implantable medical devices  
Polyethylene oxide (PEO) coatings providing improved biocompatibility for implantable medical devices are disclosed. The PEO coatings comprise functionalized end-capped PEO which is attached at one...
5639505 Reduced and controlled surface binding of biologically active molecules  
Articles of manufacture which are adapted for use in contact with one or more biologically active agents are coated with a glassy carbohydrate film. The glassy film provides a reduced surface...
5630844 Biocompatible hydrophobic laminate with thermoplastic elastomer layer  
A biocompatible hydrophobic laminate. The laminate structure includes one layer of a rubber, such as silicone rubber, which is biocompatible with the inside of the body. The laminate structure...
5628794 Multifocal corneal implant lens having a hydrogelo coating  
Hydrogel coated multifocal intraocular implantable lens having an anti-glare edge surrounded by a hydrogel ring having nutrient passage capabilities.
5614246 Method for manufacturing a sensor electrode  
In a method for manufacturing a working electrode for an implantable, electrochemical oxygen sensor a thin layer of a uniform mixture composed of an epoxy-based resin, a hardener and powdered...
5609907 Self-assembled metal colloid monolayers  
What follows is a description of an invention for the preparation of macroscopic metal surfaces by self assembly of colloidal metal particles. Metal surfaces play a critical role in technology, and...
5609631 Fibrin D-domain multimer coated prostheses and methods for their production  
Methods for coating a prosthetic surface with anti-thrombogenic, or anti-coagulant, proteins are disclosed. The methods involve contacting a surface of a prosthetic material with a composition...
5609632 Method of fabricating an artificial lung  
An artificial lung is created by taking an animal lung, filling either its circulatory system or its respiratory system with a hardenable liquid, hardening the liquid, then dissolving the natural...
5605714 Treatments to reduce thrombogeneticity in heart valves made from titanium and its alloys  
The present invention provides a method for coating a titanium based component with diamond-like carbon to reduce the thrombogeneticity of the component. In a preferred embodiment, the titanium...
5603338 Implant surface preparation utilizing acid treatment  
The surface of a device that is surgically implantable in living bone is prepared. The device is made of titanium with a native oxide layer on the surface. The method of preparation comprises the...
5587200 Method for manufacturing a medical electrode  
In a method for manufacturing electrodes for medical applications, particularly implantable stimulation electrodes, having an active layer of porous titanium nitride, a substrate of electrically...
5578079 Biocompatible, surface modified materials  
A method of permanently modifying the surface of a substrate material so as to develop a microscopically smooth, biocompatible surface thereon comprises covalently grafting a biocompatible...
5562944 Process for the protection of metallic surfaces  
A method for the protection of porous metallic surfaces, such as titanium tibial tray components, titanium hip stems, and cobalt chrome cup shells of various sizes, during machining, sandblasting,...
5545220 Implantable prosthesis with open cell textured surface and method for forming same  
A method for forming an open cell texturized surface in a silicone elastomer layer of a breast implant, or other medical implant, is created by forming a layer of uncured silicone elastomer,...
5516480 Bactericidal and/or fungicidal plastic parts for use in the medical field  
A process is provided for producing a plastic part that cannot be colonized by germs and/or fungi. The process includes the step of sequentially treating the plastic part with a swelling agent to...
5508060 Method of polymer impregnation  
Methods of impregnating various polymer substrates with an impregnation additive, by simultaneously contacting the polymer substrate with an impregnation additive, carrier liquid, and supercritical...
5505984 Method for forming biocompatible components using an isostatic press  
A method for forming a biocompatible component from a biocompatible thermoplastic material and a biocompatible fibrous material using an isostatic press. The method includes the steps of placing...
5498416 Process for the protection of prostheses and of temporarily or permanently implantable material against bacterial colonization and infection  
A method for protecting prostheses and temporarily or permanently implantable materials from bacterial colonization and infection, wherein the material is successively impregnated with: (a) a...
5474797 Bactericidal coatings for implants  
Polymeric implants provided with coatings of bactericidal compounds in the form of ionized atoms by a vapor process. The polymeric implants include products designed to penetrate or enter the body,...
5453467 Polymer treatments  
A graft polymer obtainable by grafting a polymer substrate with a compound of formula (I), in which the groups R are the same or different and each is a straight or branched C 1 -C 4 alkyl group;...
5449383 Cell growth substrates  
A process for producing a polymeric surface coating which faciliates attachment of cells on a polymeric substrate. The coating is deposited by plasma deposition of an amide monomer vapour. The...
Matches 301 - 350 out of 453 < 1 2 3 4 5 6 7 8 9 10 >