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7341757 |
Polymer nanotechnology
Size-confined nanocomposite powders and methods for their manufacture are provided by coating fine powders with a nanoscale powder of a different composition. The nanocomposite plastics offer...
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7329430 |
Method and device for coating pharmaceutical products
The present invention relates to a method for coating of a pharmaceutical product. The method comprises the step of producing discrete droplets ( 7 ) of controlled size, shape and composition with...
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7285303 |
Powder material for electrostatic application to a substrate and electrostatic application of the powder material to a substrate
Method of electrostatically applying powder material to a substrate, wherein the substrate is a pharmaceutical substrate and the powder material is pharmaceutically acceptable. At least some of the...
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7196145 |
Heterofunctional copolymers of glycerol and polyethylene glycol, their conjugates and compositions
The present invention relates to heterofunctional copolymers of glycerol and polyethylene glycol, conjugates of these heterofunctional copolymers with bioactive agents, nanoparticles, hydrophobic...
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7175873 |
Rate limiting barriers for implantable devices and methods for fabrication thereof
A method of coating an implantable medical device, such as a stent, is disclosed. The method includes applying a formulation on a first polymer layer containing a therapeutic substance to form a...
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7163690 |
Bisphosphonate coated implant device and method therefor
The method of the present invention is for coating an implant device. The implant device is coated with a protein film, such as fibrinogen. A first bisphosphonate substance, such as pamidronate, is...
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7157258 |
Particles containing coated living micro-organisms, and method for producing same
Particles containing dehydrated living micro-organisms are coated with a homogeneous layer of hydrophobic substance selected to reduce the risks of degradation of the micro-organisms by...
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7153538 |
Method and apparatus for the coating of substrates for pharmaceutical use
A method of coating a pharmaceutical substrate includes the steps of applying an active coating material to a surface of the substrate to form an active coating layer and applying a cover coating...
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7144597 |
Electrostatic application of powder material to solid dosage forms utilizing an electrically conductive shield
An apparatus for electrostatically applying a powder material to a solid dosage from includes a source ( 1 ) of charged powder material, a support assembly ( 2 ) for supporting the solid dosage...
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7132122 |
Direct micro-patterning of lipid bilayers using UV light and selected uses thereof
This invention provides novel methods for creation of patterned lipid bilayer membranes as well as methods for refunctionalization of such patterned membranes with selected components. Such...
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7090888 |
Sustained release ophthalmological device and method of making and using the same
A method of making an ophthalmological implant by applying a layer of pharmaceutical agent and an overlying layer of a bioerodible material, a biodegradable material, a bloavailable material or a...
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7083936 |
Aminodextran compositions and conjugates and method of making and using them
A composition containing polydisperse aminodextran polymer molecules is soluble in an aqueous solution at a concentration of 10 mg/ml. The molecules therein have a narrow size distribution...
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7070828 |
Process for coating solid particles
A process for coating solid particles which comprises the steps of a) contacting a gas with a fluid composition comprising i) a polymer and ii) a liquid diluent to produce a foam, and b) contacting...
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7070806 |
Controlled release formulations coated with aqueous dispersions of acrylic polymers
A stable solid controlled release formulation having a coating derived from an aqueous dispersion of a hydrophobic acrylic polymer includes a substrate including an active agent selected from the...
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7011702 |
Aqueous air foam
An aqueous air foam comprising a non-crosslinked cellulose ether selected from C1–C3-alkyl celluloses, C1–C3-alkylhydroxy-C1–3-alkyl celluloses, hydroxy-C1–3-alkyl celluloses, or mixed...
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7008668 |
Powder coating composition for electrostatic coating of pharmaceutical substrates
An apparatus and method for locking a gun. The apparatus includes a dummy round configured for insertion into a firing chamber of a gun, a locking component configured for coupling with the dummy...
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6960361 |
Split-pan for panning apparatus
A split-pan for a panning apparatus, a panning apparatus incorporating a split-pan, and a method of coating two distinct masses of centers simultaneously with the split-pan are described. The...
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6946157 |
Method and apparatus for monitoring the coating on particle during manufacturing of a pharmaceutical product
In a method of monitoring the formation of a coating on a single particle (P), an apparatus is used which comprises means ( 2,5,6,9 ) for arranging said particle (P) at a given spatial location,...
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6946156 |
Process for enrobing a core
A process for enrobing a core, such as a tablet core, uses a coating that is made of a patterned film having portions that are visually distinct (e.g, differently colored) from one another and...
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6913779 |
Process for the preparation of accelerated release formulations using compressed fluids
The following description refers to a process for the impregnation of cross-linked polymers with an active ingredient. The process is based on the used of compressed fluids, in particular CO 2 ,...
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6872336 |
Process for producing a pharmaceutical solid preparation containing a poorly soluble drug
Among the conventional processes for producing solid dispersion, the solid dispersion obtained by a solvent method is excellent in terms of solubility and bioavailability of a poorly soluble drug....
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6852335 |
Folic acid in solid dosage forms
A nutritional tablet or caplet has a film coating that contains folic acid available for rapid release upon contact with gastric fluid. The film coating also includes a film forming polymer such as...
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6844048 |
Substrates for powder deposition containing conductive domains
Provided is, among other things, a conductive inlay film comprising: a layer of dielectric film having a pattern of holes suitable to define selected regions to which particles will be deposited by...
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6821528 |
Antibiotic calcium phosphate coating
A process for applying a coating having a therapeutic agent such as an antibiotic or a bone morphogenic protein to an implant uses the high surface area of a calcium phosphate coated metal implant...
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6806017 |
Electrostatic application of powder material to solid dosage forms
In a method of electrostatically applying a powder material to a solid dosage form, charged powder material is applied to a photoconductive drum ( 3 ), is transferred to an intermediate belt ( 4 )...
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6770298 |
Device for coating granules to be administered orally
The invention concerns a device for producing granules, in particular pharmaceutical granules, comprising a drum ( 4 ) with peripheral apertures ( 25 ) and a member ( 30 ) feeding the drum with...
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6749831 |
Vaccine against lipopolysaccharide core
Compare core LPS (lacking O-polysaccharide side chains) from Gram-negative bacteria are incorporated into a vaccine typically in liposomes. The complete core of E. coli K 12 is particularly...
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6737101 |
Particle formation
Spray-coated pharmaceutical powder compositions for transdermal administration using a needleless syringe comprise seed particles coated with a pharmaceutical composition, the said coated seed...
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6723372 |
Method for producing encased spherical granular grains
A process for the production of encased, spherical granular grains comprising spraying grains which consist of a prostane derivative and a cyclodextrin vehicle, forming together a...
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6723363 |
Coating foods and pharmaceuticals with an edible polymer using carbon dioxide
A sprayable liquid coating composition, particularly for application to foodstuffs and pharmaceuticals, utilizes gaseous carbon dioxide to reduce the viscosity of a concentrated solution comprising...
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6720024 |
Methods using dry powder deposition apparatuses
Provided is, among other things, a dry deposition apparatus for depositing grains on a substrate comprising: an electrostatic chuck having one or more collection zones, wherein the substrate is...
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6716526 |
Particulate compositions and their manufacture
A composition comprising particles which comprise a core material within a polymeric shell, wherein the core material comprises a hydrophobic substance, characterized in that the polymeric shell...
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6713119 |
Biocompatible coating for a prosthesis and a method of forming the same
A coating for a prosthesis, for example a stent, and a composition for forming the coating is disclosed. The coating can serve as a primer, allowing substances, such as polymers, to be effectively...
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6709678 |
Easy to swallow oral medicament composition
An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance,...
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6703048 |
Spherical microparticles containing linear polysaccharides
Microparticles with a uniform spherical shape and a very narrow size distribution are described. They consist wholly or partly of a linear water-insoluble polysaccharide, preferably of...
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6683062 |
Multicomponent complex for use with a substrate
Compositions and methods for use with substrates which are useful in the sustained delivery of bioeffecting agents are described. The compositions of the invention include a multicomponent complex...
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6663913 |
Method of coating a bioactive substance
The invention generally provides a method of coating a material, the method including the following steps: (a) forming a generally elongate coating structure ( 15 ), the coating structure having an...
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6652903 |
Dry-copying method for producing flat, individually dosed preparations of active agents
A method for metering active ingredient in powder form onto a predetermined area is characterized in that the active ingredient is transferred as electrically charged powder to a roll with the...
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6627246 |
Process for coating stents and other medical devices using super-critical carbon dioxide
This invention provides an improved process for coating medical and surgical devices and the like using super-critical fluids.
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6623785 |
Pharmaceutical dispensing apparatus and method
An apparatus and method for manufacturing a pharmaceutical dose which dispenses a variable selectable quantity of at least one pharmaceutical onto a pharmaceutical receiving medium. The quantity of...
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6592930 |
Particle flow control
A method and a device involving an electric iris diaphragm/shutter are disclosed for controlling particle transfer of electrically charged medication powder particles from a source to a defined...
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6555156 |
Process for making absorbable microparticles
The invention pertains to a process for making encased bound microparticles by nebulizing a dispersion of the bound microparticles into a solution of an encasing polymer and into a liquid,...
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6517887 |
Method and a device for coating a tablet, a capsule, a pill or the like
The method relates to a disposable device for the application of a coating ( 2 ) on a tablet, a capsule or a pill. The coating ( 2 ) is applied enclosing the tablet, capsule or pill ( 3 ) during...
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6475351 |
AC waveforms biasing for bead manipulating chucks
AC waveforms biasing of bead transporter chucks and their accumulated charge sensing circuits tailored for low resistivity substrates and beads where if traditional DC quasi-static biasing...
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6468657 |
Controllable ion-exchange membranes
Multilayered porous materials are formed by coating a porous substrate with a metal and adsorbing an organic layer comprising a recognition moiety onto the metal film. The recognition moiety...
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6413574 |
Deposition methods utilizing carbon dioxide separation systems
A separation method includes (a) providing a heterogeneous separation system, the heterogeneous cleaning system comprising CO 2 in a first phase and an oil in a separate second phase; (b)...
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6399143 |
Method for clamping and electrostatically coating a substrate
The disclosure relates to an apparatus for electrostatically adhering grains to a planar substrate comprising: a. an electrostatic chuck having a collection surface with at least one grain...
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6391343 |
Fibrinogen-coated particles for therapeutic use
The invention provides a particle comprising fibrinogen bound on the surface of an albumin matrix, wherein said particle is capable of coaggregation with platelet, and of aggregation in a solution...
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6372876 |
Use of polyurethanes which are soluble or dispersible in water as aids in cosmetic and pharmaceutical compositions, and polyurethanes which contain polylactic acid polyols as copolymerized units
The use of polyurethanes which are—soluble or dispersible in water and are composed of a) at least one compound which contains two or more active hydrogens per molecule, b) at least one diol...
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6372246 |
Polyethylene glycol coating for electrostatic dry deposition of pharmaceuticals
The invention relates to a substrate coating for the electrostatic deposition of dry powder medicaments for use in the manufacture of pharmaceutical dosage forms comprising micronized polyethylene...
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