|
Match
|
Document |
Document Title |
|
|
7629016 |
Process for photochemical activation of polymer surface and immobilization of biomolecules onto the activated surface
The invention relates to a photochemical process for the preparation of an activated polymer surface having an active fluoro group using 1-fluoro-2-nitro-4-azidobenzene to form the activated...
|
|
|
7563483 |
Methods for fabricating a coating for implantable medical devices
Methods for fabricating coatings for implantable medical devices are disclosed. The coatings include hydrophilic and hydrophobic components. The methods provide for treatment of the coatings to...
|
|
|
7384659 |
Method of producing whole blood detecting electrode strip and reaction film formulation and the related products
The present invention relates to a method of producing a non-enzymatic whole blood uric acid detecting electrode strip for use on whole blood, characterized by comprising the step of
adding...
|
|
|
7384794 |
Micro-devices and analytical procedures for investigation of biological systems
Fibres with an extraction phase coated thereon in combination with a positioning device are described to perform adsorption of components of interest from an animal or animal tissue for the...
|
|
|
7351433 |
Method for producing polymeric sol of calcium phosphate compound and method for coating the same on a metal implant
Disclosed is a method for producing a transparent and homogenized polymeric sol of a calcium phosphate compound, containing apatite and having excellent wettability and bioactivity, according to a...
|
|
|
7232689 |
Calibration procedure for investigating biological systems
Use of calibrant in extraction phase is described for quantification of components of interest in samples in laboratory application as well as in on-site monitoring. This approach is particularly...
|
|
|
7175611 |
Antimicrobial release system
The present invention relates to medical devices that are inserted or implanted into patients and that have antimicrobial coatings that release free radicals into the vicinity of the device. These...
|
|
|
7151139 |
Antimicrobial polymeric surfaces
Bactericidal compositions are disclosed that comprise a polymeric compound immobilized on a material. Medical devices are also disclosed which comprise such a bactericidal composition. Methods are...
|
|
|
7056746 |
Array cytometry
A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution....
|
|
|
7029688 |
Methods and compositions to prevent formation of adhesions in biological tissues
The invention discloses materials that adsorb readily to the surfaces of body tissues in situ and provide a steric barrier between such tissues, so that tissue adhesions, which typically form...
|
|
|
7018518 |
Biosensor carrying redox enzymes
The present invention concerns an electrode carrying immobilized redox enzymes such that electric charge can flow between an electron mediator group to the enzyme cofactor by the use of boronic...
|
|
|
6992127 |
Polymeric coatings containing a pH buffer agent
A device containing a support member, a cross-linked polymer, and a pH buffer agent. A surface of the support member is coated with the cross-linked polymer in which the pH buffer agent is embedded.
|
|
|
6958169 |
Surface treatment of medical device
A method for improving the wettability of a medical device involves: (a) providing a medical device formed from a monomer mixture comprising a hydrophilic device-forming monomer including a...
|
|
|
6943204 |
Process for the modification of elastomers with surface interpenetrating polymer networks and elastomers formed therefrom
A process for forming a surface modification on a polymer substrate and polymer substrates having such surface modifications. The process comprises the steps of absorbing a swelling monomer into...
|
|
|
6926919 |
Method for fabricating a coating for a medical device
Methods for fabricating coatings for implantable medical devices are disclosed. The coatings include blends of hydrophilic and hydrophobic polymers. The methods provide for treatment of the...
|
|
|
6884628 |
Multifunctional polymeric surface coatings in analytic and sensor devices
Multifunctional, polyionic copolymers with molecular architectures and properties optimized for specific applications are synthesized on/or applied to substrate surfaces for analytical and sensing...
|
|
|
6844023 |
Alumina insulation for coating implantable components and other microminiature devices
A protective, biocompatible coating or encapsulation material protects and insulates a component or device intended to be implanted in living tissue. The coating or encapsulation material comprises...
|
|
|
6833128 |
Method for monitoring local reaction associated with injections
A method is disclosed for monitoring local reactions, such as inflammatory responses, associated with injection sites. The method is performed using a temporary tattoo, which is transferred from a...
|
|
|
6828028 |
Medical materials and process for producing the same
A medical material having a surface which is safe and excellent in stability with the lapse of time and has a high durability as needed in establishing a long-lasting surface lubricity in a wet...
|
|
|
6808738 |
Method of making anti-microbial polymeric surfaces
The present invention is a method for the modification of the surfaces of polymeric materials with polymer coatings that may be subsequently treated to be lubricious and anti-microbial. The method...
|
|
|
6784274 |
Hydrophilic, swellable coatings for biosensors
Methods for reducing the electrode impedance of implantable biosensors by coating the surface of the biosensor with a uniform hydrogel which allows unimpeded water movement around the sensor are...
|
|
|
6770729 |
Polymer compositions containing bioactive agents and methods for their use
Embodiments of the invention provide polymer coated implantable medical devices having a bioactive material posited in or on at least a portion of the coating layer, wherein the coating layer...
|
|
|
6755776 |
Angioplasty radiation therapy to prevent restenosis
A radiation therapy apparatus and method for significantly reducing or preventing restenosis after angioplasty utilizes a stainless steel guide wire having a phosphorus beta emitting radiation...
|
|
|
6750311 |
Detection of biological molecules using boronate-based chemical amplification and optical sensors
Methods are provided for the determination of the concentration of biological levels of polyhydroxylated compounds, particularly glucose. The methods utilize an amplification system that is an...
|
|
|
6652902 |
Gels and multilayer surface structures from boronic acid containing polymers
Boronic acid containing polymers are used to form bioinert gels and multilayer surface structures. These polymers form crosslinked hydrogels, which are highly swollen in water. The crosslinking can...
|
|
|
6558958 |
Optical fiber evanescent field excited fluorosensor and method of manufacture
An optical fiber is tapered, preferably adiabatically, and has a material coated on it for chemical bonding with fluorophores. When the fluorophores couple with the material, evanescent radiation...
|
|
|
6548168 |
Stabilized particles and methods of preparation and use thereof
A method of stabilizing particles with an insulating, semiconducting and/or metallic coating and stabilized particles prepared thereby are disclosed. In addition, particles stabilized by an...
|
|
|
6533766 |
Coating medical device surfaces for delivering gas-supersaturated fluids
A method is provided of using biocompatible surface-active agents to impart improved characteristics to a surface contacting a gas-supersaturated fluid, advantageously by forming on the surface a...
|
|
|
6472122 |
Method of applying insulation for coating implantable components and other microminiature devices
A protective, biocompatible coating or encapsulation material protects and insulates a component or device intended to be implanted in living tissue. The coating or encapsulation material comprises...
|
|
|
6428839 |
Surface treatment of medical device
The invention provides a method for improving the wettability of a medical device, comprising the steps of: (a) providing a medical device formed from a monomer mixture comprising a hydrophilic...
|
|
|
6399700 |
Comb copolymers for regulating cell-surface interactions
Synthetic comb copolymers which elicit controlled cellular response, methods of applying these polymers to various surfaces, and methods of using the polymers for modifying biomaterial surfaces, in...
|
|
|
6387379 |
Biofunctional surface modified ocular implants, surgical instruments, medical devices, prostheses, contact lenses and the like
A method for modifying the surface of a material adapted for contact with tissue of a human or non-human animal to impart biofunctional, bioactive or biomimetic properties to the surface...
|
|
|
6235340 |
Biopolymer-resistant coatings
The present invention relates to new biopolymer resistant coatings for materials that come in contact with such molecules in solution. Additionally, the present invention discloses a process for...
|
|
|
6214926 |
Silicone membranes formed without the use of 1-1-1 trichloroethane
A solvent mixture to disperse or dissolve a copolymer of methyl-trifluoropropyl siloxane and dimethylsiloxane, the solvent mixture comprising perchlorethylene, a selected acid ester, and a selected...
|
|
|
6177126 |
Process for the production of a material for sealing and healing wounds
A process for producing a material for sealing and/or healing wounds fills a liquid composition into a container having two or more plates. At least two of the plates are perforated with one or...
|
|
|
6162494 |
Method for making an optical sensor having improved barrier properties
A method for making a optical sensor for measuring the pH of a fluid includes the steps of applying a solution containing (a) a cellulose acrylamide, (b) an acrylamide, and (c) a copolymerizable...
|
|
|
6033719 |
Method for covalent attachment of biomolecules to surfaces of medical devices
A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. The method may include combining a biomolecule comprising a 1,2 dicarbonyl...
|
|
|
6030371 |
Catheters and method for nonextrusion manufacturing of catheters
An apparatus and method for nonextrusion manufacturing of catheters that can be used to produce catheters having a simple or complex configuration. A polymer material in a particulate preform is...
|
|
|
6022602 |
Plasma modification of lumen surface of tubing
The lumen surface of tubing is modified by exposure to a gas plasma in a vacuum apparatus. A method and apparatus are disclosed whereby plasma treatment of the lumen surface, such as by deposition...
|
|
|
6020071 |
Lubricious coatings
A hydrophilic lubricious coating for an article comprising a non-toxic, cross-linked, hydrophilic polyurethane. The invention includes a method for preparing said lubricious coating, as well as a...
|
|
|
6010573 |
Apparatus and method for endothelial cell seeding/transfection of intravascular stents
An apparatus for modifying an intravascular stent with endothelial cells and/or engineered endothelial cells which may have genetically altered DNA to minimize failure rates includes an external...
|
|
|
5972416 |
Bipolar electrosurgical instrument and method for making the instrument
An electrosurgical instrument having a first electrode that includes an elongated, electrically conductive member and a second electrode that includes a layer of electrically conductive material...
|
|
|
5942276 |
Method of manufacturing x-ray visible soluble covering
A method of fabricating a radiopaque dissolvable covering for a member on an implantable lead, including the steps of mixing a radiopaque material with a solvent to form a paste, applying the paste...
|
|
|
5939208 |
Method for creation of biomimetic surfaces
In the present invention method, the surface of articles made of acrylic polymers and methacrylic polymers are converted into thin biomimetic layers by using the process involving at least the...
|
|
|
5925045 |
Bipolar electrosurgical instrument
An electrosurgical instrument having a first electrode that includes an elongated, electrically conductive member and a second electrode that includes a layer of electrically conductive material...
|
|
|
5902631 |
Lubricity gradient for medical devices
A medical device for partial insertion into a patient and navigating passageways, channels, canals, cavities, and other interior parts of said patient, said medical device comprising an elongate...
|
|
|
5897819 |
Process of making a guide wire for a catheter
In a guide wire is for a catheter, a core wire prepared by twisting a plurality of thin threads in which a leading end of the core wire is diametrically reduced to be a thinnest tip. A resin layer...
|
|
|
5891506 |
Oxidative method for attachment of glycoproteins or glycopeptides to surfaces of medical devices
A method for making a medical device having at least one glycoprotein and/or glycopeptide immobilized on a substrate surface is provided. The method may include oxidizing 1,2 dihydroxy moieties...
|
|
|
5876783 |
Radiopaque medical devices
A method and apparatus for producing a guide wire including a core wire a distal portion of which is surrounded by a helically wound spring. The coils forming the distal portion of the spring...
|
|
|
5869127 |
Method of providing a substrate with a bio-active/biocompatible coating
Disclosed is a method of enhancing the biocompatibility of a substrate by providing the substrate with a continuous bio-active surface coating. This method includes applying to the substrate a...
|