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8834867 Method for producing lipase, transformed yarrowia lipolytica cell capable of producing said lipase and their uses  
Method for producing Yarrowia lipolytica acid-resistant recombinant lipase utilizing a culture medium without any products of animal origin or non-characterized mixtures such as tryptone, peptone...
8834939 Aqueous compositions of copper salts and hydrogen peroxide  
Aqueous compositions, methods of manufacturing such aqueous compositions, and methods of removing reducing and/or suppressing malodors using such aqueous compositions are described. These...
8834937 Bone filling material comprising sintered titanium dioxide and dextrin and method for reconstructing bone defects using the same  
A bone filling material comprising sintered titanium dioxide and dextrin and a method for reconstructing bone defects which comprises filling the bone defects in an animal with the bone filling...
8834935 Bone graft and biocomposite for prosthetic dentistry  
A bone graft or biocomposite for treating osseous defects and neogenesis of bone which is a composite of a biodegradable polymer and granules of beta-tricalciumphosphate, further comprising as...
8834840 Magnetic resonance imaging of self-assembled biomaterial scaffolds  
Compositions and/or mixtures comprising peptide amphiphile compounds comprising one or more contrast agents, as can be used in a range of magnetic resonance imaging applications.
8834883 Anti-VEGF antibodies and uses thereof  
Provided are monoclonal antibodies and antigen binding fragments thereof that specifically bind vascular endothelial growth factor (VEGF). The anti-VEGF monoclonal antibodies block VEGF binding to...
8834943 Compositions containing amines and use thereof  
The present invention features compositions comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of...
8834837 Method and device for radiotherapy  
A radiotherapy method, comprising positioning a predetermined amount of a radionuclide selected from the group consisting of Radium-223, Radium-224, Radon-219 and Radon-220, in proximity to and/or...
8834862 Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent  
Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of a pharmaceutical agent are described.
8834882 Antibodies to CD70  
The present invention relates to antibodies and antigen binding fragments thereof which bind to the human CD70 protein with high affinity and display potent inhibition of tumor cell growth.
8834933 Thermal treatment of acne with nanoparticles  
Provided are nanoparticles and formulations which are useful for cosmetic, diagnostic and therapeutic applications to mammals such as humans.
8834942 Enhanced absorption of oregano derived oils  
A composition for increasing the bioavailability of oregano essential oil in humans and animals comprising mixing a first emulsifier and a second emulsifier in a ratio ranging from about 1:1 to...
8834909 Granule baits  
The invention is directed at a ready-to-use granule bait composition, its preparation and use for the control of house flies inside houses and animal stalls, fodder stores and sanitary installations.
8834861 Polycarbonates for delivery of drugs and methods of preparation thereof  
A cyclic carbonate monomer has the formula (2): wherein i) t and t′ are integers independently having a value from 0 to 6 wherein t′ and t cannot both be zero, ii) each Q1 is a monovalent rad...
8835603 Agents for the treatment of celiac disease  
The invention provides agents and vaccines for treating and diagnosing celiac disease. In particular, the present invention provides a combination of three peptides that are useful for treating and...
8835119 Lectin pathway deficiency assay  
The invention refers to an in vitro method of functionally determining at physiological conditions deficiencies in the lectin pathway of the complement system, the method comprising the steps of...
8834865 Delivery system for co-formulated enzyme and substrate  
The invention provides methods, compositions, systems, and kits that include an enzyme/substrate co-delivery system. The liquid delivery system includes at least one enzyme encapsulated in a...
8834899 Photodynamic therapy-generated mesothelioma vaccine  
This invention relates to a vaccine for mesothelioma generated using photodynamic therapy and its use in methods and compositions for treating mesothelioma.
8835605 Uses of cancer-targeting peptides in cancer diagnosis  
Cancer-targeting peptides and uses thereof in cancer diagnosis.
8835599 Segmented degradable polymers and conjugates made therefrom  
The present invention provides, among other things, segmented, degradable polymeric reagents suitable for reaction with biologically active agents to form conjugates, the polymeric reagents...
8835492 Temperature and pH sensitive block copolymer and polymeric hydrogels using the same  
Disclosed is a block copolymer formed by coupling the following components with each other: (a) a copolymer (A) of a polyethylene glycol (PEG) type compound with a biodegradable polymer; and (b) at...
8834923 Slow-release composition, method for the preparation thereof, and use thereof  
The pharmaceutical or nutraceutical composition with sustained release of an active ingredient according to the present invention comprises at least one coated granule; the coated granule being...
8834920 Liposome composition for targeting egfr receptor  
Short oligopeptides are provide which are capable of binding to the epidermal growth factor receptor on the surface of human tumor cells. Methods for using the peptides as targeting moieties in...
8835609 Antigen binding sites to non-functional oligomeric P2X7 receptors and methods of use thereof  
The invention relates to purinergic receptors, to antibodies and related fragments thereof for binding to said receptors, to production of said antibodies and fragments and to use of said...
8834873 Method for detecting and controlling cancer  
Methods are provided for treating cancer metastasis by administering a therapeutic composition targeting a kinase substrate cascade.
8834927 Thermogelling anaesthetic compositions  
The present invention relates to a thermogelling pharmaceutical composition comprising local anaesthetics in base form and which is suitable for topical administration. The compositions further...
8835606 Anti-cancer antibodies with reduced complement fixation  
The invention provides modified antibodies directed against GD2 that have diminished complement fixation relative to antibody-dependent, cell-mediated cytotoxicity, which is maintained. The...
8834924 Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane  
The present invention relates to an immediate release solid oral dosage form containing 1-aminocyclohexanes, preferably memantine or neramexane, and optionally a pharmaceutically acceptable...
8834844 Chemical exchange saturation transfer based MRI using reporter genes and MRI methods related thereto  
Featured are a new class of reporter genes including reporter compositions as well as methods, MRI systems and MRI imaging kits related thereto. The genes according to the present invention provide...
8834906 Color capsule composition for cosmetics, preparation method thereof and cosmetic formulation comprising the same  
Disclosed herein are a color capsule composition, which contains a polymer and a plasticizer swelling the polymer so as to allow the capsule particles to easily break and in which the capsule...
8834772 Antimicrobial methacrylate cements  
Bone cement compositions and methods of making two-part bone cements. The methods comprise transferring premixed powder and a liquid component into a receptacle, and mixing the powder component and...
8834918 Modified multilayered film  
A composition for delivery of a molecule into a cell is provided. The composition includes a protein transduction domain that is conjugated to the molecule which is incorporated into a multilayered...
8834928 Tissue-derived tissugenic implants, and methods of fabricating and using same  
The disclosure provides implants containing a plurality of particles containing at least one population of viable tissuegenic cells adherent to and resident in the growth-conductive matrix or at...
8835508 Stable aqueous solution containing sodium pyruvate, and the preparation and use thereof  
A stable aqueous solution of sodium pyruvate for medical use, which contains 10-1,200 mM sodium pyruvate and a stabilizer of sodium pyruvate, wherein the said stabilizer is H+ which leads to pH...
8835398 Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis  
Isolated polynucleotide sequences exhibiting endothelial cell specific promoter activity, novel cis regulatory elements and methods of use thereof enabling treatment of diseases characterized by...
8835619 Heat shock proteins from Mycobacterium leprae and uses thereof  
The present invention is directed to heat shock proteins from Mycobacterium leprae as well as their encoding polynucleotides and vectors and host cells containing these polynucleotides. These heat...
8835162 Methods of incorporating amino acid analogs into proteins  
The invention provides a method of incorporating nonstandard amino acids into a protein by utilizing a modified aminoacyl-tRNA synthetase to charge the nonstandard amino acid to a modified tRNA,...
8835513 Drug delivery devices  
Compositions provided by contacting a biotin-containing component and an avidin-containing component are useful as drug delivery devices. Bioactive agents may be covalently bound to the...
8834875 Notch1 binding agents and methods of use thereof  
The present invention relates to Notch1 binding agents and methods of using the agents for treating diseases, such as hematologic cancers. The present invention provides antibodies that...
8834892 Method of preparing live viral vaccines by genetic engineering of viral genome  
Disclosed is an attenuation method of an influenza virus, that is, a reassortant virus and a preparation method thereof. The disclosed reassortant virus has, in a ratio of 6:2, genes encoding a...
8835556 Hydrolytically stable maleimide-terminated polymers  
The present invention is directed to conjugates of hydrolytically stabilized maleimide-functionalized water soluble polymers and to methods for making and utilizing such polymers and their precursors.
8834951 Dry glassy composition comprising a bioactive material  
The present invention relates to formulations and methods for stabilizing and protecting of biologic materials during harsh storing and use conditions, wherein the formulations relate to embedded...
8834903 Nanoemulsion based on sugar fatty esters or on sugar fatty ethers and its uses in the cosmetics, dermatological and/or ophthalmological fields  
A nanoemulsion, the oily globules of which have a number-average size of less than 100 nm, comprising a surfactant which is solid at a temperature of less than or equal to 45° C., which surfactant ...
8834979 Bag for forming an implantable artificial organ  
A pouch for forming an implantable artificial organ, including a closed shell provided in a semi-pervious membrane. The pouch further includes a sheet contained within the shell, the sheet...
8835608 Anti-MRP3 antibodies and methods of use  
An antibody having an antigen binding region capable of binding an epitope located in an extracellular portion of MRP3 and methods of utilizing same are provided. In particular, the invention...
8834874 Methods and compositions for increasing iduronate 2-sulfatase activity in the CNS  
Provided herein are methods and compositions for treating a subject suffering from a deficiency in iduronate 2-sulfatase in the CNS. The methods include systemic administration of a bifunctional...
8834863 Subfamily E simian adenoviruses A1321, A1325, A1295, A1309, A1316 and A1322 and uses thereof  
Recombinant vectors comprise simian adenovirus A1321 (SAdV-A1321), SAdV-A1325, SAdV-A1295, SAdV-A1309, SAdV-A1316, and/or SAdV-A1322 sequences and a heterologous gene under the control of...
8834838 Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma  
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present...
8834839 Labeled molecular imaging agents, methods of making and methods of use  
Imaging agents that comprise labeled substrates of the cystine/glutamate antiporter of cells, whereby the methods of use comprise introducing the labeled agents into cells via the cystine/glutamate...
8835378 Multi-domain amphipathic helical peptides and methods of their use  
Disclosed herein are peptides or peptide analogs with multiple amphipathic α-helical domains that promote lipid efflux from cells via an ABCA1-dependent pathway. Also provided herein are methods ...