Sign up


Match Document Document Title
8871269 Method for the preparation of controlled release formulations  
The methods disclosed herein are of use for the production of controlled release compositions. In particular, the methods provide the contacting of an organic phase containing a bioactive agent and...
8871244 Vaginal suppository comprising lactic acid  
The present invention relates to a vaginal suppository comprising an inert vehicle and lactic acid or a salt thereof for the treatment and/or prophylaxis of disorders in the urogenital tract. It...
8871268 Biodegradable polymeric networks and methods for manufacturing the same  
Methods of manufacturing a three-dimensional, biodegradable, thermoset polymeric network composition having desirable degradation and mechanical properties, comprising a macromer component...
8871213 Prevention, treatment and diagnosis of P. gingivalis infection  
The invention relates to generation and use of cellular and humoral responses for the prevention and treatment of P. gingivalis related conditions and diseases.
8871205 Methods and compositions for the treatment of immune disorders  
The present invention provides a method of treating an immune-related disorder in a subject, comprising administering to the subject an effective amount of an inhibitor of plexin-A4 activity, which...
8871995 Method for screening an agent being useful for the treatment of dry eye and/or corneal and conjunctival lesion and pharmaceutical composition obtained by the method  
The present invention provides a method for screening an agent being useful for the treatment of dry eye and/or corneal and conjunctival lesion of dry eye severity level 3 or more according to the...
8871211 Cancer vaccines and vaccination methods  
Methods and compositions for treating cancers (e.g., neural cancers) by dendritic cell vaccination are provided herein.
8871230 Conjugate with target-finding ligand and use thereof  
Described is a conjugate of agent complex and at least one target-finding ligand, where the agent complex comprises an agent encapsulated by an encapsulation material and where the target-finding...
8870845 Method for alleviating condition of spinal canal stenosis by local administration of medicine  
Disclosed herein is a method for alleviating the condition of spinal canal stenosis, including: transluminally placing a catheter in a lumbar artery, iliolumbar artery or lateral sacral artery at...
8871908 Antibodies specific for Trop-2 and their uses  
The present invention provides antibodies that specifically bind to trophoblast cell-surface antigen-2 (Trop-2). The invention further provides antibody conjugates comprising such antibodies,...
8871224 Botulinum toxin therapy for skin disorders  
Methods for treating skin disorders by local administration of a Clostridial toxin, such as a botulinum toxin, to a patient with a skin disorder.
8871220 Newcastle disease virus vectored avian vaccines  
The present invention encompasses engineered Newcastle Disease Virus (NDV) vaccines or compositions. The vaccine or composition may be a recombinant vaccine. The invention also encompasses...
8871209 Compositions and methods for increasing muscle mass and muscle strength by specifically antagonizing GDF8 and or Activin A  
The present invention provides compositions and methods which involve specifically antagonizing GDF8 and Activin A. In certain embodiments, compositions are provided which comprise a GDF8-specific...
8871492 Anti-dementia substance from Hericium erinaceum and method of extraction  
A fat-soluble fraction extracted from the fruiting body of Hericium erinaceum is demonstrated to inhibit the neuronal toxicity of amyloid beta-peptide (Aβ) and induce the synthesis of nerve growth ...
8871910 Antibodies inhibiting c-Met dimerization, and uses thereof  
The present inventions relates to a process for the selection of anti c-Met antibodies capable to inhibit both ligand-dependent and ligand-independent activation of c-Met. More particularly, said...
8871225 Canine leishmania vaccine  
The present invention provides vectors that contain and express in vivo Leishmania KMP11 or an epitope thereof that elicits an immune response in a dog against Leishmania, compositions comprising...
8871251 Liposome and method for producing the same  
A liposome including a neutral lipid membrane, a positively charged polymer, and a surface active polymer is provided. The neutral lipid membrane is formed as a hollow sphere, the positively...
8871263 Manufacture of tablet in a die utilizing radiofrequency energy and meltable binder  
The present invention features a process for making a tablet by (i) compacting a powder blend in a die to form a tablet shape, wherein the powder blend contains a pharmaceutically active agent and...
8871192 IL-1F8 polypeptides  
The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins.
8871239 Polymeric materials for medical devices  
The present invention includes biocompatible polymeric coatings, membranes, matrices, and films to be used with implantable medical devices. Medical devices containing such materials applied to a...
8871259 Techniques and systems for treatment of neuropathic pain and other indications  
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of neuropathic pain or other conditions. In some cases, the composition may include...
8871238 Medical devices and coatings therefore comprising biodegradable polymers with enhanced functionality  
Biodegradable polymers useful for fabricating implantable medical devices and as coatings for medical devices are provided. The biodegradable polymers are biocompatible and can be tuned to provide...
8871253 Liposome having inner water phase containing sulfobutyl ether cyclodextrin salt  
A liposome comprising bilayer and inner water phase is disclosed. Said inner water phase contains sulfobutyl ether cyclodextrin and active compound. Said sulfobutyl ether cyclodextrin is sulfobutyl...
8871254 Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system  
The present invention generally relates to compositions and methods for treatment of subjects having or at risk of acne or other conditions. In some cases, the composition may include nitric oxide....
8871229 Cosmetic composition for long-wearing properties  
Disclosed are cosmetic compositions comprising (1) at least one MQTPr siloxane resin; (2) at least one film former chosen from a silicone acrylate copolymer; (3) at least one film former chosen...
8871207 Neutralizing anti-influenza A virus antibodies and uses thereof  
The invention relates to antibodies, and antigen binding fragments thereof, that specifically bind to an epitope in the stem region of an influenza A hemagglutinin trimer and neutralize a group 1...
8871236 Biocompatible polyacrylate compositions for medical applications  
A composition comprising a structural component comprising linear acrylic homopolymers or linear acrylic copolymers and a biobeneficial component comprising copolymers having an acrylate moiety and...
8871223 HSV-1 and HSV-2 vaccines and methods of use thereof  
This invention provides methods of vaccinating a subject against a Herpes Simplex Virus (HSV) infection and disorders and symptoms associated with same, and impeding, inhibiting, reducing the...
8871181 Fluorescent phospholipid ether compounds, compositions, and methods of use  
The invention generally relates to novel fluorescent phospholipid compounds, compositions comprising these compounds, and diagnostic methods utilizing these compounds. A preferred compound of the...
8871708 Compositions and methods for treating AIDS or cancer by inhibiting the secretion of microparticles  
Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also...
8871242 Blood anticoagulant material, coating material and indwelling device comprising the same, and treatment using blood anticoagulant material  
A blood anticoagulant material is provided which has high expandability, reduced influence on living bodies, and can efficiently prevent blood coagulation. A multiblock copolymer having at least a...
8871710 Method for inducing tissue growth, differentiation and/or regeneration by delivering a GDF-5 related precursor protein  
This invention relates to the production and use of pharmaceutical growth factor compositions with novel characteristics, e.g. improved solubility and controlled release characteristics under...
8871187 Oxoazetidine derivatives, process for the preparation thereof and use thereon in human medicine and in cosmetics  
Compounds derived from oxoazetidine corresponding to general formula (I) compositions containing same, processes for their preparation and their use in pharmaceutical or cosmetic compositions are...
8871277 Particulate wood preservative and method for producing the same  
A wood preservative includes injectable particles comprising one or more sparingly soluble copper salts. The copper-based particles are sufficiently insoluble so as to not be easily removed by...
8871247 Hemostatic compositions and therapeutic regimens  
The present invention relates generally to the field of hemostasis, including methods, compositions, and devices that can be employed to treat wounds. More specifically the present invention...
8871267 Protein matrix materials, devices and methods of making and using thereof  
The present invention relates to protein matrix materials and devices and the methods of making and using protein matrix materials and devices. More specifically the present invention relates to...
8871190 Polymeric pheromone formulation and method of use to calm stress-related behavior in mammals over an extended period of time  
Pheromone compositions comprising a combination of squalene, linoleic acid and 1-docosanol are described, along with methods of using the pheromone compositions to modify behavior in mammals. The...
8871189 MMP-targeted therapeutic and/or diagnostic nanocarriers  
The present invention provides targeted delivery compositions and methods of using the compositions for treating and diagnosing a disease state in a subject.
8871185 Lip makeup composition with good staying power comprising a low molecular weight resin  
The present disclosure relates to a lip makeup composition comprising at least one resin chosen from rosins, rosin derivatives and hydrocarbon-based resins, and mixtures thereof, wherein the at...
8870954 Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries  
The invention provides compositions and methods for treatment of tendon and ligament injuries and/or repair of damaged tendons and ligament. The invention provides compositions comprising a...
8870945 Bioabsorbable device having composite structure for accelerating degradation  
A medical device has a structure made of a first biodegradable and/or bioabsorbable material and a second biodegradable and/or bioabsorbable material encapsulating a degradation additive...
8871725 Pharmaceutical combination for the treatment and/or chemosensibilization of refractory tumors to anticancer drugs  
This invention is related to a pharmaceutical combination that contains a Casein kinase 2 (CK2) peptide inhibitor (termed P15) along with the standard chemotherapeutic drugs used in cancer...
8871186 Compositions and methods for control of malodor and other environmental contaminants  
Nanocomposite compositions forming mixed clathrates and methods for using such compositions for entrapping guest moieties such as malodors, molds and cells are disclosed.
8871275 Extended release compositions comprising tolterodine  
The present invention deals with extended release pharmaceutical compositions comprising tolterodine, wherein the composition comprises: a) a drug layer comprising tolterodine tartrate,...
8871241 Injectable sustained release delivery devices  
An injectable drug delivery device includes a core containing one or more drugs and one or more polymers. The core may be surrounded by one or more polymer outer layers (referred to herein as...
8871279 Use of the combination of PHY906 and a tyrosine kinase inhibitor as a cancer treatment regimen  
This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life...
8871191 Use of IL-15 preparations to treat lymphopenia  
The present invention provides method for promoting the maturation and export of T cells from thymic tissue by contacting the thymic tissue with supraphysiological levels of interleukin (IL)-15....
8871280 Compositions and methods for treating fungal activity in plants or soil  
Compositions for treating fungal activity in plants, containing castor oil, water, at least one surface active agent, optionally pennyroyal oil, and optionally an agriculturally acceptable carrier....
8871727 Ectoparasiticidal methods and formulations  
Provided are novel methods and formulations for topically controlling ectoparasite infestations in animals using spinetoram or a pharmaceutically acceptable salt thereof.
8871812 Therapeutic regimen comprising PEG-interferon, ribavirin and VX-950 for the treatment of hepatitis  
The present invention relates to antiviral therapies and compositions for treating or preventing Hepatitis C infections in patients and relates to other methods disclosed herein. The invention also...