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9226956 Immunization against Clostridium difficile disease  
The invention provides active and passive immunization methods for preventing and treating Clostridium difficile infection, which involve percutaneous administration of C. difficile...
9220820 Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings  
Coatings for medical devices, methods of making the coatings, and methods of using them are described.
9181527 T cell receptor-deficient T cell compositions  
The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In...
9169323 Antibodies against human CSF-1R  
The present invention relates to antibodies against human CSF-1R (CSF-1R antibody), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
9149547 Process for production of heterodimers of glutamic acid  
A manufacturing process for the preparation of radiolabeled compounds of formula (I) includes reacting compounds of formula (II) with a source of readionuclide of a halogen in the presence of an...
9138601 Method of improving skin regeneration effect of medicinal materials by double boiling using earthenware pot  
Disclosed is a method capable of improving the skin regeneration effect of medicinal materials through double boiling using an earthenware pot. The method shows an excellent skin regeneration...
9101543 Combinations and modes of administration of therapeutic agents and combination therapy  
The present invention provides combination therapy methods of treating proliferative diseases (such as cancer) comprising a first therapy comprising administering to an individual an effective...
9089616 Anti-DLL3 antibody drug conjugates and methods of use  
Novel modulators, including antibodies and derivatives thereof, and methods of using such modulators to treat proliferative disorders are provided.
9089529 Antibody formulations and methods  
Antibody formulations and methods useful for prophylaxis or treatment of amyloidosis, including AA amyloidosis and AL amyloidosis.
9089484 Pharmaceutical compositions of selective factor Xa inhibitors for oral administration  
The present invention provides pharmaceutical compositions for oral administration comprising a therapeutically effective amount of a selective factor Xa inhibitor or a pharmaceutically acceptable...
9085624 Antibodies directed to the deletion mutants of epidermal growth factor receptor and uses thereof  
The present invention relates to novel antibodies, particularly antibodies directed against deletion mutants of epidermal growth factor receptor and particularly to the type III deletion mutant,...
9073802 Method for producing 18F-labeled compound and high molecular compound to be used in the method  
The present invention aims at solving the problems of conventional methods for producing an 18F-labeled compound, that is, the problem of purification of a compound in a liquid phase synthesis...
9055742 Herbicide granules with built-in adjuvant  
Provided herein are herbicide granules containing non-petroleum derived built-in adjuvant.
9055763 Probiotics for use in relieving symptoms associated with gastronitestinal disorders  
The present invention provides probiotic compositions suitable for relieving symptoms associated with gastrointestinal disorders. In particular, the present invention provides compositions and...
9040020 Muteins of hNGAL and related proteins with affinity for a given target  
The present invention relates to novel muteins derived from human lipocalin 2 (hNGAL) and related proteins that bind a given non-natural ligand with detectable affinity. The invention also related...
9040092 Materials and methods for altering an immune response to exogenous and endogenous immunogens, including syngeneic and non-syngeneic cells, tissues or organs  
Disclosed herein are materials and methods for modulating an immunologically adverse response to an exogenous or endogenous immunogen, including a cell, tissue, or organ associated immunogen. An...
9040098 Soluble canola protein isolate production (“nutratein”)  
Canola protein isolates are provided which contain both albumin and globulin protein fractions that are soluble, transparent and heat stable in an acidic aqueous environment. The canola protein...
9040050 Combination treatment of CD38-expressing tumors  
The invention relates to novel method for the treatment of cancer using a combination therapy comprising an antibody that binds CD38, a corticosteroid and a non-corticosteroid chemotherapeutic agent.
9040043 Monoclonal antibodies against GMF-B antigens, and uses therefor  
The disclosure relates to anti-glial maturation factor beta (“GMF-B”) monoclonal antibodies (mAbs) and fragments thereof, as well as hybridoma lines that secrete antibodies or fragments....
9040091 Compositions and methods for oral delivery of encapsulated diethylenetriaminepentaacetate particles  
The present disclosure is directed to compositions comprising encapsulated particles of diethylenetriaminepentaacetate (DTPA) and a zinc salt such as zinc acetate, and to pharmaceutical...
9040106 Pharmaceutical composition for preventing or treating diabetic erectile dysfunction comprising C3G or extract of mulberry containing C3G  
The present invention relates to the ameliorating effects of C3G (Cyanidin-3-O-β-d-glucopyranoside) on diabetic erectile dysfunction. In particular, the present invention relates to a...
9040035 Treatment of pain using placental stem cells  
Provided herein are methods of treatment of an individual having pain, e.g., neuropathic pain, comprising administering to the individual a therapeutically effective amount of tissue culture...
9040077 Patch and patch preparation  
The present invention provides to a patch and a patch preparation having low stretchability, which can be continuously adhered to the skin for a long time without undesirable detachment and marked...
9040067 Disinfecting and antimicrobial compositions  
Broad spectrum disinfecting and microbicidal compositions of biodegradable and environmentally friendly compositions containing esters formed from fatty organic alcohols and fatty carboxylic...
9040061 Topical formulation for administering a compound  
Embodiments of topical formulations for administering compound I or a pharmaceutically acceptable salt or solvate thereof are disclosed. Embodiments of methods for using the topical formulations...
9040102 Composition comprising longan arillus extract or combined extract comprising the same for treating neurodegenerative disease  
This disclosure relates to a composition for prevention or treatment of neurodegenerative disease comprising longan arillus extract, or combined extract comprising longan arillus. The composition...
9040080 Processing of heat-sensitive active agents  
The present disclosure relates to a method of melt processing an active agent. The method may include encapsulating an active agent in a first polymer material exhibiting a first processing...
9040105 Nanocrystals and amorphous nanoparticles and method for production of the same by a low energy process  
A process for the production of nanocrystals or amorphous nanoparticles of actives (nanomaterials), especially from the peels of grapes. A dispersion of a micrometer-sized material in a solution...
9040055 Conjugation of streptococcal capsular saccharides  
Three conjugation methods for use with the capsular saccharide of Streptococcus agalactiae. In the first method, reductive animation of oxidized sialic acid residue side chains is used, but the...
9040024 Composition and aerosol spray dispenser for eliminating odors in air  
An air treating composition for eliminating airborne malodors and/or sanitizing air in combination with a spray valve and actuator and spray performance parameters providing maximum dispersion of...
9040068 Control of bed bugs  
A method of combating bed bugs and/or other insects in a locus containing or susceptible to presence of same, in which a DMSO-containing formulation is applied to the locus. Various pesticidal...
9040096 Jasmonic acid compounds in cocoa products  
The invention provides methods for isolating and enhancing the levels of jasmonates from cacao plant sources. In a preferred embodiment, jasmonic acid and 12-hydroxy jasmonate sulfate are detected...
9040057 Method of diagnosing and preventing pneumococcal diseases using pneumococcal neuraminidases  
A method of providing protection against pneumococcal infection in a subject is disclosed. The method includes steps of administering to the subject a composition that includes combination of...
9040085 Delayed release tablet with defined core geometry  
A tablet comprising a core containing an active agent, and a coating, the core being disposed within the coating such that the coating has a thickness about a longitudinal axis (X-Y) of about 4.85...
9040095 Colon cleansing of residual stool and secretions during colonoscopy  
This invention relates, e.g., to a composition comprising two or more of: (a) N-acetylcysteine and/or (b) simethicone and/or (c) a docusate salt. In one embodiment of the invention, the amounts of...
9040060 Hydrolytically degradable alkylene oxide based polymers  
The present invention provides a water soluble, non-peptidic polymer comprising two or more alkylene oxide-based oligomers linked together by hydrolytically degradable linkages such as carbonates....
9040668 Anti-serum albumin binding variants  
The invention relates to improved variants of the anti-serum albumin immunoglobulin single variable domain DOM7h-11, as well as ligands and drug conjugates comprising such variants, compositions,...
9040049 ADAM-15 antibodies and immunogenic peptides  
The present invention relates to antibodies and antigen-binding fragments thereof, immunogenic peptide(s), and siRNA molecules which are capable of inhibiting neovascularization and/or...
9040034 Vitamin functionalized gel-forming block copolymers for biomedical applications  
Gel-forming block copolymers were prepared comprising i) a central hydrophilic block consisting essentially of a divalent poly(ethylene oxide) chain and ii) two peripheral monocarbonate or...
9040018 Monoclonal antibodies against alpha-actinin-4 antigens, and uses therefor  
Monoclonal antibodies (MoAbs or mAbs) specific for ALPHA-ACTININ-4 antigens, hybridoma lines that secrete these ALPHA-ACTININ-4 mAbs, and the use of such mAbs to detect ALPHA-ACTININ-4 antigens,...
9040048 Antibody molecules having specificity for human OX40  
The invention relates to antibody molecules having specificity for antigenic determinants of human OX40, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
9040031 Hair care composition  
A personal care composition comprising: i) a cleaning phase comprising a cleansing anionic surfactant which is a salt and comprises an alkyl group with from 8 to 14 carbons; ii) an aqueous...
9040075 Method of increasing lean body mass and reducing body fat mass in infants  
Disclosed is a method of increasing lean body mass and reducing fat body mass in infants, said method comprising administration to an infant, term or preterm, a nutritional formula comprising a...
9040021 Heterocyclic compounds as imaging probes of tau pathology  
Heterocyclic compounds of formula (I) useful as imaging probes of Tau pathology in Alzheimer's disease are described. Compositions and methods of making such compounds are also described.
9040073 Silk polymer-based adenosine release: therapeutic potential for epilepsy  
The invention provides formulations comprising adenosine in a silk fibroin-based, sustained-release delivery system. The formulations provide sustained, focal release of adenosine at therapeutic...
9040094 Flaky particle and cosmetic  
The present invention has an object to provide a flaky particulate material giving skin an excellent smoothness, which is free from whitening problem upon use thereof owing to its high...
9040101 Method to treat diabetes utilizing a gastrointestinal microbiome modulating composition  
Compositions and methods for treating diabetes are presented herein. In particular, the present disclosure teaches compositions and methods for treating diabetes utilizing a gastrointestinal...
9040040 Enzyme combinations to reduce brain tissue swelling  
Tissue fixed charge density (FCD) is identified as another potential therapeutic target for reducing brain tissue swelling. Reduction of the FCD could reduce the thermodynamic force driving water...
9039979 Apparatus and method of reacting polymers passing through metal ion chelated resin matrix to produce injectable medical devices  
The present disclosure relates to an apparatus and process for forming medical devices from an injectable composition. The apparatus includes a supply assembly configured to maintain and selective...
9040058 Fermentation media free of animal-derived components for production of diphtheria toxoids suitable for human vaccine use  
The present invention relates to a fermentation medium for cultivating Corynebacterium diphtheriae. The present invention also relates to the use of the fermentation medium in processes for...