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8785599 FcγRIIB—specific antibodies and methods of use thereof  
The present invention relates to antibodies or fragments thereof that specifically bind FcγRIIB, particularly human FcγRIIB, with greater affinity than the antibodies or fragments thereof bind F...
8785139 Modification-dependent activity assays  
Disclosed herein are methods, systems and kits to measure the presence and/or activity of recombinant polypeptides comprising a modification.
8785614 Aberrantly methylated genes in pancreatic cancer  
The present invention provides a method for detecting pancreatic carcinoma in a subject. The method includes contacting a nucleic acid-containing specimen from the subject with an agent that...
8785603 Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof  
Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a...
8784815 Human CTLA-4 antibodies and their uses  
The present invention provides novel human sequence antibodies against human CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
8784900 Antimicrobial solutions containing dichlorine monoxide and methods of making and using the same  
Methods and products are provided for treating a wound or infection in a mammal or disinfecting a surface with a hypochlorous acid solution that has been activated by a catalyst. Additionally...
8784860 Local administration of a combination of rapamycin and cilostazol for the treatment of vascular disease  
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to...
8784106 Dental preparation delivery system  
A dental preparation delivery system includes a soft malleable wax sealing strip bonded to a wax base strip. The peripheral outline of a model dentition extends into the thickness of the sealing...
8784875 Collagen for use in the treatment of skin diseases  
The invention relates to collagen for use in the treatment of inflammatory and degenerative skin diseases and damage to the skin connected therewith, such as in particular in the treatment of...
8784848 Method for preparing a stable oil-in-water emulsion  
The invention relates to a method for preparing a stable oil-in-water emulsion without adding an emulsifier. According to the method, a mixture of a lipid phase and an aqueous phase is subjected to...
8784872 Formulation for decreasing tobacco, alcohol, drug or food consumption  
Formulations have been developed which assist individuals having an addiction such as smoking to reduce or quit engaging in the addictive behavior. Representative behaviors include smoking,...
8784772 Urothelial differentiation of urothelial carcinoma: a bladder cancer stem cell model  
The present invention provides a method of treating cancer in a patient (e.g., a human patient) in need thereof, the method comprising administering a therapeutically effective regimen, the regimen...
8784849 Hydroxyapatite-targeting poly(ethylene glycol) and related polymers  
Isolatable, hydroxyapatite-targeting polymeric structures, and biologically active conjugates thereof, are provided. The polymeric structure includes a linear or branched water-soluble and...
8784827 Chimeric fusion proteins and virus like particles from Birnavirus VP2  
The field of the invention refers to chimeric Virus Like Particles (VLP) derived from Birnavirus chimeric VP2 protein. In particular, the invention refers to chimeric VP2 fusion proteins which...
8784901 Synergistic antimicrobial preparations containing chlorite and hydrogen peroxide  
An anti-microbial preservative for use in ophthalmic and dermatologic products. The preservative includes from about 0.005 wt. % to about 0.20 wt. % chlorite compound and from about 0.005 wt. % to...
8784823 Binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind CD154 and uses thereof  
This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a CD154 (CD40L) protein. This invention also provides a chimeric,...
8785197 Compositions for regenerating defective or absent myocardium  
Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an...
8784880 Titratable dosage transdermal delivery system  
The present invention relates to a titratable dosage transdermal delivery system for systemic delivery of a therapeutic agent or drug. The system comprises a plurality of patch units that are...
8784877 Transdermal levonorgestrel device and delivery  
Described are transdermal drug delivery systems for the transdermal administration of levonorgestrel, comprising a polymer matrix and levonorgestrel acetate. Methods of making and using such...
8784811 Method of treating cancer using antibodies to a non-ligand binding region of NOTCH1  
The present invention relates to compositions and methods for characterizing, diagnosing, and treating cancer. In particular the invention provides the means and methods for the diagnosis,...
8784907 Compositions and methods for improving the appearance of aging hair  
A hair care composition and method of using the composition is provided that can increase the appearance of thicker and/or fuller hair and/or delay the appearance of gray hair to provide healthy...
8784776 Use of FSH receptor ligands for diagnosis and therapy of cancer  
The present invention relates to diagnostic imaging and in particular to the diagnostic imaging and therapy of cancer by means of compositions which specifically target the FSH Receptor expressed...
8784816 Antibodies which bind factor VIII  
The invention, in general, features a method of treatment and/or prevention of a thrombotic pathological condition, in a mammal, which includes administering to the mammal in need of such treatment...
8784779 Color change of chalcone-containing oral care formulations  
Oral care compositions and methods are described in which the composition includes a chalcone color change component, which may be phenyl-3-methoxy-4-hydroxystyryl ketone. The color change...
8784784 Organic compounds  
Deodorant composition for the treatment of female malodour comprising a perfume containing violet nitrile and optionally pharaone and/or zinarine.
8784876 Clay-based hemostatic agents and devices for the delivery thereof  
A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh....
8785399 Antibacterial peptides  
The present invention relates to monomeric and multimeric peptidic compounds which have antimicrobial activity, particularly against Gram-positive and Gram-negative bacteria. Further, the present...
8785194 Serum-free mammalian cell culture medium, and uses thereof  
The present invention provides a cell culture medium formulation that supports the in vitro cultivation, particularly in suspension, of mammalian cells, particularly epithelial cells and fibroblast...
8784832 Synthetic antigen based on the ligand domain of the Plasmodium vivax duffy binding protein  
The disclosure provides compositions that are useful for eliciting a strain-transcending immune response in an animal or human directed against the blood-stage of the malarial parasite Plasmodium...
8785411 HIV DNA vaccine methods of use  
The present invention is directed to a DNA vaccine for immunization against HIV. The invention comprises a DNA molecule that has a sequence encoding a plurality of viral proteins capable of...
8784805 Method for increasing the activity of the immune system of a mammal at risk of inflammatory diseases  
The present invention relates to methods for increasing the activity of the immune system and, especially, to methods for increasing the activity of the immune system by modulation of endogenous...
8784843 Stabilizers for freeze-dried vaccines  
The present invention relates generally to the fields of immunology and vaccine technology. More specifically, the present invention relates to stabilizers for freeze-dried live attenuated...
8784885 Controlled release preparation  
A controlled release preparation wherein the release of active ingredient is controlled, which releases an active ingredient for an extended period of time by staying or slowly migrating in the...
8784893 Polymer formulations for delivery of bioactive agents  
Disclosed in the present application are compositions comprising a bioresorbable polymer matrix and a bio active agent, wherein the bioactive agent is dispersed within polymer matrix as a solid....
8785605 Humanized IL-25 antibodies  
The present invention relates to target binding members (e.g., antibodies) that bind a specified epitope of human IL-25. The invention also relates to target binding members (e.g., antibodies) that...
8784794 Long-term storage of non-glycosylated recombinant human G-CSF  
The present invention provides a method for stable long-term storage of non-glycosylated recombinant human Granulocyte-Colony Stimulating Factor (“G-CSF”), wherein an aqueous acetate or glu...
8784825 Modulators of MYC, methods of using the same, and methods of identifying agents that modulate MYC  
Disclosed herein are methods of modulation of the viability of a cell. Further disclosed herein are methods of modulating an immune response. Further disclosed herein are methods of identifying...
8785186 Hybrid cells for treating cancer patients  
The present invention relates to cancer treatment compositions and methods for treating a specific cancer patient population. In particular, the application describes methods of treating a patient...
8784844 Arabinogalactan for enhancing the adaptive immune response  
The present invention discloses a composition containing Arabinogalactan for enhancing the adaptive immune response in subjects to foreign antigen(s) by administering said composition prior, during...
8784882 Controlled release delivery system for nasal applications and method of treatment  
This invention relates to a gel formulation for nasal administration of a controlled release formulation of hormones to the systemic circulation and/or to the brain. The special lipophilic or...
8784886 Coating capsules with active pharmaceutical ingredients  
Pharmaceutical compositions in unit dose form comprising capsules containing one or more first active pharmaceutical ingredient in a pharmaceutically acceptable vehicle, coated with one or more...
8784810 Treatment of amyloidogenic diseases  
The invention provides preferred dosage ranges, maximum concentrations, average concentrations and monitoring regimes for use in treatment of Alzheimer's disease using antibodies to Aβ. The ...
8784903 Medicinal plants extract using processing of herbal medicine and composition of skin external application comprising the same  
The present invention relates to an extract of a processed herbal medicinal plant and a composition for skin external application which contains the extract. More specifically, the composition for...
8784777 Flexibly labeling peptides  
A solid phase peptide synthesis method for synthesizing a peptidyl contrast agent is disclosed. In one example, the method includes synthesizing an amino-chelator loaded resin, coupling of the...
8784879 Transdermal administration of tamsulosin  
In an aspect of the invention, a composition for making a patch for the transdermal delivery of tamsulosin is provided. The composition comprises (a) at least about 1 wt % tamsulosin or a...
8784786 Rheology modifier polymer  
A polymer includes (a) one or more first monomeric units, each independently comprising at least one bicycloheptyl-polyether, bicycloheptenyl-polyether or branched (C5-C50)alkyl-polyether group per...
8784873 Use of histone deacetylase inhibitors in changing MRJP3 protein in royal jelly  
The invention provides a method of changing a ratio of 68 to 64 kDa protein of MRJP3 in a royal jelly, a method of producing a royal jelly comprising MRJP3 having a changed ratio of 68 to 64 kDa...
8784842 Allelic exchange mutagenesis in Map  
Particular aspects provide efficient allelic exchange methods to generate directed mutations within genes of slow-growing stains of mycobacteria (e.g., Mycobacterium avium subsp. paratuberculosis...
8784782 Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions  
The inventions disclosed herein relate to the discovery of the use of compounds having the formula shown below and certain subgenera or species thereof, as flavor or taste modifiers, particularly,...
8786720 Biological specimen observation method  
When a biological specimen, such as living cells, biological tissue, or a small animal, is quantitatively observed, the specimen is observed for a long time or over a long period, while maintaining...