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7258856 |
Proteases from Carica having mitogenic activity and their methods of use
Proteases having mitogenic activity isolated from the genus Carica are provided. In particular the proteases are cysteine proteases isolated from Carica candamarcensis. In addition, the...
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7211278 |
Treating method for suppressing hair growth
treating method for hair growth inhibition, which comprises administering (A) the extract of a plant of the family Juniperus or a malt. In addition, the present invention relates to a dermatologic...
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7169405 |
Methods and devices for the treatment of intervertebral discs
Methods for treating at least one condition of an intervertebral disc (e.g. protrusion, hemiation, discogenic pain, dehydration, or degeneration) in a patient in need thereof are provided. The...
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7166281 |
Pharmaceutical composition and method for relieving itch, pain and swelling resulting from insect bites and stings
A pharmaceutical composition for relieving the itch, pain, and swelling resulting from insect bites and stings, and methods for producing and using the composition. The method preferably comprises...
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7125544 |
Kit for promoting the growth of human hair and its method of use
Provided is a kit that composes of two products and its method of use to promote hair growth. The kit has two products that are applied to the scalp of a human sequentially. The first product...
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7083964 |
Method for purifying enzymes from clostridium histolyticum using multi-stage chromatography
The invention relates to a method for purifying at least one enzyme obtained in an excess fermentation of Clostridium histolyticum. It is provided for that the enzymes of the excess...
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7078024 |
Compositions and method for promoting the growth of human hair
Provided are compositions comprising monoethanolamine salts of thioglycolic, salicylic, lactic and glycolic acids in combination with an organic enzyme, preferably papain, and an oxidizing aged...
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7056499 |
Treating method for suppressing hair growth
The present invention relates to a treating method for hair growth inhibition, which comprises administering (A) the extract of a plant of the family Juniperus or a malt. In addition, the present...
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7041302 |
Therapeutic modulation of the tumor inflammatory response
The invention relates to compositions, kits, and methods for alleviating cancer (i.e., a tumor) in a human patient. The therapeutic modality effected by the invention involves inducing a type 1...
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6958150 |
Reduction of adipose tissue
The amount of adipose tissue, including lipomas, at selected locations in the body is reduced by introducing collagenase or collagenase plus another proteinase into the tissue.
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6927053 |
Dual component dental composition containing enzyme
A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing an enzyme such as papain and a second dentifrice component containing an...
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6806070 |
Use of bacterial extracts of the pseudomonadaceae family as cosmetic agents
Use of an extract of bacterium from the family Pseudomonadaceae in the production of cosmetic compositions in particular for combating ageing of the skin.
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6803038 |
Use of bromelaine proteases for inhibiting blood coagulation
The present invention relates to the use of bromelaine proteases for inhibiting blood coagulation, especially for stimulating the production of plasmin, for inhibiting the production of fibrin and...
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6800473 |
Human cathepsin L2 protein, gene encoding said protein and use thereof
Novel proteins which belong to the papain family and are cysteine proteinase enzymes (the cysteine proteinase enzymes are expected to be involved in the turnover of intracellular proteins, antigen...
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6783757 |
Composition and method for increasing exorphin catabolism to treat autism
A composition for use in treating autism spectrum disorders. The composition preferably includes a genomeceutical type compound that increases the user's expression of DPPIV or like substances. The...
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6773704 |
Methods of treating vascular disease associated with cystatin C deficiency
The invention provides methods of treating and preventing vascular diseases, by inhibiting cysteine proteases active at sites of vascular injury, particularly cathepsins K and S, by administering...
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6709651 |
Treatment of substance P-related disorders
The present invention is directed to methods of treating a wide variety of diseases, disorders and conditions characterized by excessive activity of substance P. The treatment involves...
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6645509 |
Polypeptide expressed in the horny layer of epidermis and use thereof
The present invention relates to a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, a purified natural or synthetic epidermis-specific polypeptide which is...
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6627193 |
Methods and compositions for control of blood coagulation
Methods for controlling blood coagulation, and suitable pharmaceutical compositions that include a polypeptide that enhances the anticoagulation process (or inhibitors thereof for reversing the...
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6623735 |
Vaccine containing a thiol protease
Thiol proteases having Cathepsin 1 type activity are used in the formulation of vaccines for combating helminth parasites. Preferably the protease is derived from a fluke such as Fasciola hepatica.
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6548556 |
Stable enzymatic wound debrider
This invention relates to an enzymatic anhydrous hydrophilic wound debrider that uses in combination a proteolytic enzyme and an anhydrous hydrophilic poloxamer carrier.
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6544767 |
Cathespin O2 protease
The invention relates to cathepsin O2 proteins, nucleic acids, and antibodies.
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6444791 |
Methods and compositions for the treatment of keratoconus using protease inhibitors
Compositions and methods for treating corneal diseases mediated by elevated protease activity include ocular administration of protease inhibitors. One or more protease inhibitors selected from an...
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6426099 |
Herbal formulation for rebuilding intestinal bacteria
An herbal formulation comprises betaine HCl, plant enzymes, papain, probiotic micro flora, fruitooligosaccharides, l-glutamine, quercitin, butyric acid, borage seed, flax seed, lecithin, gamma...
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6419923 |
Filariid nematode cysteine protease proteins, and uses thereof
The present invention provides for filariid nematode cysteine protease proteins; to filariid nematode cysteine protease nucleic acid molecules, in particular, Dirofilaria immitis L3 larval...
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6416756 |
Modified protease having 5 to 13 covalently coupled polymeric molecules for skin care
Modified enzymes are prepared for use in skin care products by covalently coupling to the enzymes from 4 to 70 polymeric molecules with or without a linker such as a triazine ring. Molecular weight...
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6413512 |
Composition and method for treating disease by increasing activated α2 macroglobulin in the blood and extravascular tissue
A method for treating various diseases and conditions that are dependent on activated α 2 macroglobulin in the blood and extravascular tissue is disclosed. The method comprises orally...
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6399059 |
Thermally stable enzyme composition and method of preparing the same
A thermally stable enzyme composition contains an enzyme, and a heat stabilizer including a phospholipid and an oil-soluble vitamin. The enzyme composition can be prepared in the form of a powder...
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6346245 |
Procedure for extraction and use of hatching fluid from Atlantic salmon
A procedure is described for obtaining valuable endoproteases (or zonases) from hatchery-produced Atlantic salmon eggs. Synchronized hatching by for instance elevated temperature, is followed by...
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6338847 |
Compositions and methods to disinfect contact lenses
Compositions and methods to disinfect contact lenses are disclosed. In one embodiment, the present composition comprises a cellulose decomposing enzyme component, e.g., lysozyme, and a hydrogen...
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6294169 |
Interleukin-1 beta converting enzyme like apoptotic protease-6
Human ICE LAP-6 polypeptides and DNA (RNA) encoding such ICE LAP-6 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing...
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6280728 |
Treatment of hepatitis C virus infection using a protease and a flavonoid
The use of at least one hydrolytic enzyme and at least one flavonoid shows better activity than α-interferon or ribavirin in the treatment of diseases caused by hepatitis C viruses.
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6274141 |
Enzymatic dietary treatment for hydrolyzing BSA
A method and apparatus enable the immune system of an infant to distinguish between ABBOS protein sections and p69 protein sections and reduces the risk that an infant will develop diabetes. The...
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6265198 |
Parasite astacin metalloendopeptidase proteins
The present invention relates to parasite astacin metalloendopeptidase proteins, nucleic acid molecules having sequences that encode such proteins, antibodies raised against such proteins and...
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6214572 |
Programmed cell death and ICH-3
This invention relates to modulation of programmed cell death. It also relates to transgenic non-human animals comprising a disrupted Ich-3 gene and methods of making these animals. The Ich-3...
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6177072 |
Soy hydrolysate and use in insect control
Soy hydrolysate compositions are produced by a process utilizing multiple enzymes. The soy hydrolysate compositions provide insect attractant and repellent properties. Methods of using the soy...
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6096307 |
Compositions for immunostimulation containing Echinacea angustofolia, bromelain, and lysozyme
A composition for immunostimulation contains an effective amount of an Echinacea extract, Bromelain and Lysozyme. In particular, a treatment for excessive bacterial growth in the oral cavity...
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6080403 |
Protease containing hairball remedy and use thereof
Animal food formulations, preferably dry cat foods and treats, or medicaments, e.g., tablets, gels or suppositories, that contain an amount of an enzyme (bromelain) effective to treat and/or...
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6066488 |
Cathepsin C homolog
The present invention provides nucleotide and amino acid sequences that identify and encode a new cathepsin C homolog (RCP) expressed in THP-1 cells. The present invention also provides for...
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5972317 |
Composition and method for treating diseased nails
A nail-permeable medication means is disclosed for delivering a medicament through nails, claws, hoofs, or other similar hardened tissue of dermal derivation. The nail-permeable medication means...
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5965129 |
Two novel human cathespin proteins
The present invention provides two novel human cathepsin proteins (HCPs) and polynucleotides encoding HCPs. The invention provides for genetically engineered expression vectors and host cells...
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5928640 |
Use of enzymes, especially bromelain, in the treatment of diarrhoea
Enzymes, especially proteolytic enzymes such as bromelain, have been found to inhibit the action of heat-labile toxin (LT) of enterotoxigenic Escherichia coli. They are therefore useful in the...
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5916557 |
Methods of repairing connective tissues
The present invention relates to the use of an ECM-altering enzymatic activity, such as a proteoglycanase or a protease, to stimulate the generation of cartilage tissue by inducing chondrocytes to...
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5853705 |
Anti-aging cosmetic composition
An anti-aging cosmetic composition in which is blended an enzymolyzed substance obtained by treating by one or more enzymes an alkali extract of a hypoallergenic rice obtained by treating rice in...
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5830739 |
Proteolytic mixture containing escharase and method of isolating same
Method is described for obtaining a novel proteolytic mixture containing escharase from bromelain.
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5824305 |
Method of treating diseases mediated by cyclic nucleotide pathways with purified stem bromelain protease
The present invention relates to a method of treating various diseases and conditions which are dependent on cyclic nucleotide pathways with purified stem bromelain protease. Administration of...
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5811095 |
Basal and chitinase broth compositions for enhancing anti-fungal activity of a chemical fungicide and methods for preparing and using same
An insecticidal composition and its method of preparation are presented. The composition comprises a basal broth, a chitinase broth and a chemical fungicide. The basal broth has proteins hydrolyzed...
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5688502 |
Animal growth promotant
A growth promotant comprising microgranules having a core consisting of one or more enzymes selected from: i) protein digesting enzymes; ii) carbohydrate digesting enzymes; iii) fat digesting...
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5603936 |
Process for removing light absorbing compounds from epidermal plant cells
A process is provided for harvesting light absorbing compounds from the epidermal cells of a plant. The plant is subjected to artificial light having wavelengths in the range of 260 to 400 nm. The...
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5597564 |
Method of administering a microgranular preparation to the intestinal region of animals
A microgranular preparation having a core of biologically active material that is encapsulated by a water soluble film that is covered by an enteric coating of either an alkali soluble, acid...
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