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7338766 |
Compositions and methods for treating malaria with cupredoxin and cytochrome
The present invention relates to cupredoxin and cytochrome and their use, separately or together, to inhibit the spread of parasitemia in mammalian red blood cells and other tissues infected by the...
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7335383 |
Generation of nitric oxide in vivo from nitrite, nitrate or nitrosothiols endogenous in blood
A material includes a surface and a reactive agent that is located at the surface of the material, covalently attached to a backbone of the material, and/or located within the material. The...
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7332159 |
Method and composition for inhibiting reperfusion injury in the brain
The present invention relates to a method for inhibiting reperfusion injury in the brain. The method involve injecting via the carotid artery or jugular vein an antioxidant-loaded nanoparticle. A...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7306944 |
Advanced cell-transducing transport domain-target protein-transport domain fusion protein and uses thereof
The present invention provides a fusion protein which delivers a functional protein or peptide into a cell at enhanced efficiency. The fusion protein of the present invention is a transduction...
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7282202 |
Interleukin-6 suppressive agent
An interleukin-6 suppressive agent comprising lactoperoxidase as an active ingredient is used as a pharmaceutical preparation or the like for prevention and/or therapy of a disease caused by...
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7270814 |
Odor control compositions and methods
The present invention relates to the use of a carbohydrate oxidase to reduce or prevent malodor. The present invention also relates to a deodorizing composition comprising a carbohydrate oxidase.
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7267818 |
Method for killing spores
A method for killing or inactivating spores, by contacting the spores with a haloperoxidase, a source of hydrogen peroxide and a source of iodide ions. The spores may additionally be contacted with...
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7255857 |
Lysyl oxidase-like 1 (LOXL1) and elastogenesis
Described are methods of treating and preventing conditions associated with a loss of elastic fibers. Also provided herein are methods of screening for agents useful in treating such conditions,...
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7247441 |
Nucleic acid sequence and protein in addition to polypeptides coding for mannitol dehydrogenases or parts thereof and the production and use thereof in diagnosis and therapy
The invention relates to polypeptides made of mannitol-dehydrogenase of Cladosporium herbarum and Alternaria alternata nucleic acids coding therefor and the use thereof in diagnosis and therapy.
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7217415 |
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase for therapeutic use
According to the present invention, a series of genes are identified in Group B Streptococcus , the products of which may be located on the outer surface of the organism. The genes, or functional...
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7211249 |
Heat-generating composition for topical application to skin
The present invention provides a method of sustaining the rate of heat felt on the skin as a result of an exothermic reaction between a combination of an unencapsulated and an encapsulated...
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7208301 |
Method for producing 6-0-α-D-glucopyranosyl-D-sorbitol
This invention concerns a method for enzymatic preparation of 6-O-α-D-glucopyranosyl-D-sorbitol (1,6-GPS) from isomaltulose. It is specified that the isomaltulose is put into an aqueous reaction...
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7198785 |
Systems and methods related to degradation of uremic toxins
The present invention generally relates to the treatment of uremic toxins in vivo using uremic toxin-treating enzymes, and/or cells capable of producing uremic toxin-treating enzymes or otherwise...
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7182949 |
Composition comprising vitamin C prepared during application, use of enzymes for forming vitamin C for topical use, and a cosmetic treatment method
The invention concerns a composition for topical application for extemporaneous preparation, comprising ascorbic acid and a suitable support, the ascorbic acid being obtained by bringing at least...
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7153666 |
Methods and compositions for determination of glycated proteins
This invention relates generally to the field of glycated protein detection. In particular, the invention provides chimeric proteins, nucleic acids encoding the chimeric proteins, methods and kits...
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7150870 |
Anti-tumor agent
The invention prevents or treats a tumor, inhibiting tumor growth and malignant progression by providing an antitumor agent containing a treated SOD as the active ingredient, especially a melon SOD...
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7128904 |
Material containing metal ion ligand complex producing nitric oxide in contact with blood
Biocompatible materials that have the ability to release nitric oxide (NO) in situ at the surface-blood interface when in contact with blood. The materials which may be polymers (e.g.,...
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RE39321 |
Supplemented and unsupplemented tissue sealants, methods of their production and use
This invention provides a fibrin sealant dressing, wherein said fibrin sealant may be supplemented with at least one composition selected from, for example, one or more regulatory compounds,...
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7067125 |
Antimicrobial polypeptides and methods of use
Antimicrobial compounds and compositions and uses thereof, including the treatment and prevention of bacterial infections are described. The compounds and compositions include lantibiotic...
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7041655 |
Capillary membrane stabilization and reduction of tissue injury through use of IV biodegradable macromolecules with antioxidants and/or other chemicals
In accordance with the invention there is provided a method of treating a human subject to prevent leakage of serum proteins from capillary endothelial junctions during a period of increased...
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7037697 |
Isozyme of autoclavable superoxide dismutase (SOD), a process for the identification and extraction of the SOD and use of the said SOD in cosmetic, food, and pharmaceutical compositions
The invention relates to a novel purified isozyme of an autoclavable superoxide dismutase extracted from the plant Potentilla atrosanguinea Lodd. Var. areyrophylla, said isozyme having the...
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7018822 |
Guanosine monophosphate reductase
The present invention provides a human guanosine monophosphate reductase (HGMPR) and polynucleotides which identify and encode HGMPR. The invention also provides genetically engineered expression...
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7011826 |
Control of acidosis
The present invention relates to a vaccine for the prevention of lactic acidosis in a vertebrate, said vaccine comprising at least one isolated microorganism, or fragment or fragments thereof,...
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6989143 |
Depletion method of blood plasma ascorbate
Artificial modulation of ascorbate level was investigated in mice capable of de novo synthesis of ascorbate. When mice were given exogenous ascorbate or its physiological precursor,...
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6967020 |
Oxygen carrier system, artificial oxygen carrier, and reducing agent
An oxygen carrier system includes an artificial oxygen carrier including hemoglobin vesicles encapsulating hemoglobin and an intermediate electron mediator having a standard electrode potential of...
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6953571 |
Cosmetic or pharmaceutical composition for topical use to prevent or differ androgenetic alopecia
A cosmetic-pharmaceutical composition for topical use against human alopecia containing a pool of enzymes of the specific hydroxisteroido-dehydrogenase group in the presence of...
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6942663 |
Laser treatment of cutaneous vascular lesions
Methods for treating maladies such as cutaneous vascular lesions. A patient in need of vascular lesion treatment is identified. A hyperosmotic agent is administered to a region adjacent the lesion....
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6939685 |
Stabilized tetrazolium phenazine reagent compositions and methods for using the same
Stabilized tetrazolium dye-phenazine reagent compositions and methods for their use in the measurement of an analyte in a sample are provided. The subject reagent compositions include: (1) a...
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6932966 |
Topically applied reconstituted ocean water mixture and method of producing and using the mixture
A skin treatment mixture for treating pierced skin such as that resulting from a body piercing procedure includes sea salt, lysozyme and reconstituted ocean water. The reconstituted ocean water...
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6924135 |
DNA encoding Eimeria glyceroaldehyde-3-phosphate dehydrogenase and uses thereof
This invention relates to a novel DNA encoding Eimeria glyceroaldehyde-3-phosphate dehydrogenase (GAPDH) and recombinant GAPDH protein expressed using the DNA sequence. The present invention...
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6913915 |
PEG-modified uricase
The present invention is directed to uricase modified with polyethylene glycol and to methods of treating different illnesses characterized by increased circulating uric acid levels, including but...
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6893865 |
Methods, compositions, and cells for encapsidating recombinant vectors in AAV particles
Isolated recombinant polynucleotides comprising elements which promote encapsidation into AAV particles, packaging cells comprising the recombinant polynucleotides, and methods for their use are...
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6893633 |
Methods and compositions for promoting the maturation of monocytes
Disclosed is a method of promoting the maturation of monocytes comprising the administration of a reactive oxygen species (ROS) inhibitor or scavenger and at least one monocyte maturation-promoting...
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6887467 |
Double mutants of dihydrofolate reductase and methods of using same
New mutant forms of human dihydrofolate reductase (DHFR) which have properties superior to the previously disclosed mutants have mutations at both amino acid 22 and amino acid 31 . Specific...
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6884416 |
Stable PQQ-dependent glucose dehydrogenase composition
The present invention provides a stable lyophilized PQQ-dependent glucose dehydrogenase composition comprising a PQQ-dependent glucose dehydrogenase together with (i) at least one compound selected...
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6872388 |
Degradation of cercosporin by laccase
Disease in plants caused by infection with cercosporin producing strains of Cercospora may be controlled by application of laccase. When applied to the locus of the plant, or parts or seed...
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6866869 |
Liquid antimicrobial compositions
A liquid antimicrobial composition comprises:
(1) a mixture of iodide anions and thiocyanate anions; (2) periodic acid or an alkali metal salt thereof; and (3) optionally, a peroxidase.
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6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
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6818212 |
Antimicrobial composition containing a haloperoxidase, a hydrogen peroxide source, a halide source and an ammonium source
An enzymatic antimicrobial composition comprising a haloperoxidase, a hydrogen peroxide source, a halide source, and an ammonium source, in particular an ammonium salt or an aminoalcohol, in which...
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6808707 |
Wound healing compositions and methods using tropoelastin and lysyl oxidase
The present invention provides compositions and methods for promoting wound healing. The composition comprises virgin monomers of tropoelastin and lysyl oxidase. When the lysyl oxidase comes in...
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6783965 |
Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
A naturally occurring or recombinant protein, especially a mutein of porcine urate oxidase (uricase), that is essentially free of large aggregates can be rendered substantially non-immunogenic by...
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6709650 |
Spray-dried microparticles and their use as therapeutic vehicles
Microparticles of a water-soluble material, which are smooth and spherical, and at least 90% of which have a mass median particle size of 1 to 10 μm, and which carry a therapeutic or diagnostic...
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6696058 |
Aqueous enzymatic denture adhesives
Hydro-activated and/or oxygen activated aqueous, enzymatic, antimicrobials denture adhesive compositions are stabilized against enzymatic action prior to oral application of the adhesive by...
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6682732 |
Treatment of lesions
A composition for use in the treatment of lesions of the human or animal body comprises xanthine oxidoreductase and a pharmaceutically acceptable electron donor system. The composition can...
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6677433 |
Stabilization of hypoallergenic, hyperdigestible previously reduced proteins
Disulfide proteins showed mitigated allergenicity and increased digestibility by pepsin following reduction by thioredoxin. The sulfhydryl groups newly formed on reduction by thioredoxin (at 4°...
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6638526 |
Polypeptides conjugated to copolymers of ethylene oxide and propylene oxide to reduce allergenicity
A polypeptide-polymer conjugate is prepared having one or more polymers covalently bound to a polypeptide. The polymer has the general formula; EO X PO Y wherein EO is ethylene oxide, PO is...
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6630003 |
Colouring agents with enzymes
The present invention relates to a composition for coloring keratin fibers containing at least one dye precursor and a choline-based oxidase system. The present invention also relates to a process...
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6610520 |
Gene encoding human manganese superoxide dismutase and recombinant polypeptide encoded thereby
A double-stranded cDNA molecule which includes DNA encoding human manganese superoxide dismutase has been created. The sequence of one strand of a double-stranded DNA molecule which encodes human...
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6592890 |
Conveyance of anti-infective activity to wound dressings
A wound dressing having anti-infective activity. The wound dressing provides stable and improved formulations of precursors required in generating anti-infective iodine specifically within a wound...
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