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6323321 |
Antibody 97A6
The present invention relates to a monoclonal antibody binding an antigen on the megakaryocytic cell line UT-7. The invention further relates to hybridoma cells producing such an antibody.
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6316012 |
Cosmetic or pharmaceutical composition comprising, in combination, a peroxidase and an anti-singlet oxygen agent
A method of preventing damage caused to healthy skin, hair or mucous membranes by free radicals, includes applying to the healthy skin, hair or mucous membrane a composition containing at least one...
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6313268 |
Secretases related to Alzheimer's dementia
This invention is directed to a novel β-secretase that produces the Aβ peptide found in Alzheimer's Disease. One β-secretase is a protein having a molecular weight of about 61, 81 or 88 kDa that...
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6312687 |
Stabilized lactoperoxidase and glucose oxidase concentrate
A stabilized aqueous enzyme concentrate composition which comprises: a) 1000 to 1800 units/ml of lactoperoxidase; b) 1500 to 2750 units/ml of glucose oxidase; c) 10 to 20% w/v of an alkali...
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6312686 |
Modulating the permeability of a physiological barrier with an agent that modulates tyrosine phosphorylation
Permeability of the blood-brain barrier and other physiological barriers can be modulated by the degree of tyrosine phosphorylation of proteins. Agents which promote tyrosine protein...
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6303127 |
Treatment of disease states
The invention presents methods for the treatment of symptoms associated with diseases states including cardiomyopathy, Parkinson's Disease and degenerative liver disease including cirrhosis...
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6303119 |
Personal care compositions containing subtilisin enzymes bound to water insoluble substrates
The present invention relates to personal care compositions comprising a water insoluble substrate, a plurality of Protease G enzymes, and a binding means, permanently attaching each of the enzymes...
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6300098 |
Human signal transduction serine/threonine kinase
An isolated and purified human Ste20-like serine/threonine signal transduction kinase is described. A cDNA sequence which encodes the native signal transduction molecule is disclosed as well as the...
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6290951 |
Alteration of the cell cycle in vivo, and particularly for inducing apoptosis of tumor cells
A first substance (such as the peptide aldehydes LLnL and LVP) inhibits the function of intracellular proteasome. A second substance (such as ranpirnase) inhibits intracellular protein synthesis or...
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6291533 |
Dietary supplements for each specific blood type
Dietary supplement compositions designed to be responsive to specific blood types, and thus most beneficial for people with specific antigenic blood types.
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6284246 |
Modified polypeptides with high activity and reduced allergenicity
The present invention relates to a modified polypeptide which has an enzymatic activity level of greater than about 70% of the parent polypeptide and an allergenic response level of less than about...
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6280725 |
Compositions and methods for inhibiting the growth of fungi
A composition suitable for inhibiting the outgrowth of fungi is provided comprising a first ingredient which inhibits the biogenesis of a normal fungal cell wall and a second ingredient which is...
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6280727 |
Compositions containing thrombin and microfibrillar collagen and methods for preparation and use thereof
The present invention relates to thrombin-containing hemostatic compositions, their preparation and use. In particular, it relates to hemostatic compositions comprising stabilized thrombin and...
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6277965 |
CysS
The invention provides cysS polypeptides and DNA (RNA) encoding cysS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing cysS...
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6277399 |
Composition incorporating bacterial phage associated lysing enzymes for treating dermatological infections
A composition for treatment of bacterial infections of burns and wounds of the skin comprises an effective amount of at least one lytic enzyme produced by a bacteria infected with a bacteriophage...
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6270762 |
tdk
The invention provides tdk polypeptides polynucleotides encoding tdk polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tdk...
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6267956 |
Protein activator and apoptosis
An isolated and purified human protein activator of apoptosis is described. A cDNA sequence which encodes the native kinase of death is disclosed as well as the structural coding region and the...
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6268344 |
Methods for treating hypercoagulable states or acquired protein C deficiency
A method of treatment for human patients with an acquired hypercoagulable state or acquired protein C deficiency associated with sepsis, purpura fulminans, meningococcal sepsis, bone marrow and...
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6264945 |
Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections
The present invention discloses a method and composition for the treatment of bacterial infections by the parenteral introduction of at least one lytic enzyme produced by a bacteria infected with a...
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RE37274 |
Method for nutritional oxygenation of the skin
A skin treatment process designed to reduce the aging process of the skin and to cause the skin to become a semi-permeable membrane. The steps include exfoliation, cleansing, hydration, and...
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6254866 |
Use of phage associated lytic enzymes for treating bacterial infections of the digestive tract
A method for treatment of bacterial infections of the digestive tract is disclosed which comprises administering a lytic enzyme specific for the infecting bacteria. The lytic enzyme is preferably...
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6254869 |
Cryptopain vaccines, antibodies, proteins, peptides, DNA and RNA for prophylaxis, treatment and diagnosis and for detection of cryptosporidium species
Vaccines, antibodies, proteins, DNAs and RNAs for diagnosis, prophylaxis, treatment and detection of Cryptosporidium species or Cryptosporidium species infections. Cryptosporidium species antigen...
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6242175 |
Methods and means relating to retrotransposon and retroviral integration
Ku(Ku70 and Ku80) of yeast and mammalian cells and other components of the Ku-associated DNA repair pathway are involved in retrotransposon and retroviral integration into cellular nucleic acids....
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6242010 |
Synergistic antioxidant compositions in management of hemorrhoids and other ano-rectal inflammatory conditions
Compositions for remediating ano-rectal inflammatory processes, hemorrhoidal syndromes and ano-rectal wounds. The composition includes the synergistic combination of reduced glutathione and...
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6231853 |
Human glutathione peroxidase-6
The invention provides a human glutathione peroxidase (GPx6) and polynucleotides which identify and encode GPx6. The invention also provides expression vectors, host cells, antibodies, agonists,...
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6232292 |
3-dehydroquinate synthase
The invention provides 3-DEHYDROQUINATE SYNTHASE polypeptides and DNA (RNA) encoding 3-DEHYDROQUINATE SYNTHASE polypeptides and methods for producing such polypeptides by recombinant techniques....
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6228625 |
metK from Streptococcus pneumoniae
The invention provides metK polypeptides and polynucleotides encoding metK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for...
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6228323 |
Multi-purpose compositions containing an alkyl-trypsin and methods of use in contact lens cleaning and disinfecting
Two-compartment bottle assemblies useful in preparing multi-purpose compositions containing an Al-trypsin and disinfectant, methods of preparing these compositions and methods involving the use of...
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6217862 |
TCTS response regulator
Novel response regulator polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for...
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6217861 |
Response regulator polypeptides of Streptococcus pheunoniae
The invention provides Response Regulator and Histidine Kinase polypeptides and DNA (RNA) encoding such polypetides and methods for producing such polypeptides by recombinant techniques. Also...
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6218350 |
Bleaching enzymes
There is provided a bleaching enzyme capable of generating a bleaching chemical and having a high binding affinity for stains present on fabrics. Furthermore, there is provided an enzymatic...
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6214338 |
Plasma concentrate and method of processing blood for same
A plasma concentrate comprising one of platelets and platelet releasate and from 5 to 400 mg/ml of fibrinogen. The concentrate further includes a physiologically acceptable carrier comprising water...
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6207148 |
Disease associated protein kinases
The invention provides human disease associated protein kinases and polynucleotides (collectively designated DAPK) which identify and encode them. The invention also provides expression vectors,...
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6207149 |
Starch binding domains (SBDs) for oral care products
The present invention relates to an oral care composition comprising a Starch Binding Domain and further ingredients conventionally used in oral care compositions, oral care products, and the use...
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6207729 |
Texturized cellulosic and lignocellulosic materials and compositions and composites made therefrom
Texturized cellulosic or lignocellulosic materials, and compositions and composites made therefrom, are disclosed.
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6207200 |
Use of proteins as anti-retroviral agents
The present invention relates to the discovery that a protein, having a molecular weight of about 14 Kd, extracted with perchloric acid from animal organs such as goat liver, has anti-retroviral...
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6207151 |
Aqueous solution of t-PA
Aqueous protein-containing solutions, in which a protein is dissolved at a high concentration at a pH near the isoelectric point of the protein by adding an anionic polymer or a salt thereof to the...
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6200564 |
Pharmaceutical compositions containing chondroitinase and uses therefor
Gastrointestinal mucus from patients suffering from cystic fibrosis has been found to contain large amounts of chondroitin sulfate polymer. This finding indicates that the enzyme chondroitinase is...
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6190680 |
Oily composition and process for producing the same
An oily composition comprises a solid phase containing a water-soluble effective substance and/or a water-dispersible effective substance and an oil phase containing an oily component and an...
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6190894 |
Method and compositions for disrupting the epithelial barrier function
A method for disrupting epithelial barrier function in a host in need of the topical administration of a physiologically active substance which comprises applying to the epithelium of the host,...
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6177072 |
Soy hydrolysate and use in insect control
Soy hydrolysate compositions are produced by a process utilizing multiple enzymes. The soy hydrolysate compositions provide insect attractant and repellent properties. Methods of using the soy...
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6162786 |
Bacterial infection-preventive agent for fish and shellfish larvae, and method for breeding them
A new effective bacterial infection-preventive agent for fish and shellfish larvae is provided. This agent contains a protease inhibitor such as ovomacroglobulin, α 2-macroglobulin or an analog...
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6156523 |
Serine/threonine protein kinases
The invention provides human serine/threonine protein kinases (HSTK) and polynucleotides which identify and encode HSTK. The invention also provides expression vectors, host cells, antibodies,...
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6146624 |
Human ubiquitin-conjugating enzymes
The invention provides a human ubiquitin-conjugating enzyme (HUBI) and polynucleotides which identify and encode HUBI. The invention also provides expression vectors, host cells, agonists,...
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6146626 |
Defined enzyme mixtures for obtaining cells and treating wounds
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6139859 |
Methods and compositions for topical treatment of ectoparasites
Methods and compositions for the topical treatment of ectoparasites on animal skin utilizing a water-soluble or water-dispersible, substantially air-impermeable liquid composition.
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6139837 |
ATP-dependent RNA helicase protein
The invention provides a human ATP-dependent RNA helicase (ADRH-1) and polynucleotides which identify and encode ADRH-1. The invention also provides expression vectors, host cells, agonists,...
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6140475 |
Controlled dissolution crosslinked protein crystals
Protein crystals crosslinked with a multifunctional crosslinking agent are produced that have the ability to change from an insoluble and stable form to a soluble and active form and to release...
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6140063 |
In vitro screening assay for identification of compounds that inhibit cytopathicity of viral infection
The present invention includes the method of treating a viral infection, specifically one occurring as a result of infection by a human immunodeficiency virus (HIV-1). The method of treatment...
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6136606 |
Influenza vaccine compositions
The invention provides a vaccine composition in the form of a kit, comprising a first container containing an antigenic preparation comprising influenza antigen or antigens; and a second container...
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