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6685937 |
Chewing gum containing phage associated lytic enzymes for treating streptococcal A infections
A chewing gum composition produced by mixing an effective amount of lysin enzyme produced by group C streptococcal bacteria infected with a C1 bacteriophage and a carrier for delivering said lysin...
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6676933 |
Pharmaceutical composition containing mosapride and pancreatin
A pharmaceutical composition contains mosapride, pancreatin and optionally simethicone and is used for treating, preventing or alleviating the symptoms of a gastrointestinal disorder. The...
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6677440 |
Process for the preparation in pure form of the protease activating blood clotting factor VII, its proenzyme or a mixture of both proteins by means of ion-exchange chromatography
A process for the preparation of a pure form of protein, wherein the protein is protease activating blood clotting factor VII, the proenzyme for the protease, or a mixture of both the-protease and...
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6673586 |
Steroid hormone receptor interacting protein kinase
The present invention features a novel p21-activated kinase that interacts with steroid hormone receptors, the steroid hormone receptor interacting p21-activated kinase (PAK SI ). In general, the...
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6638526 |
Polypeptides conjugated to copolymers of ethylene oxide and propylene oxide to reduce allergenicity
A polypeptide-polymer conjugate is prepared having one or more polymers covalently bound to a polypeptide. The polymer has the general formula; EO X PO Y wherein EO is ethylene oxide, PO is...
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6635247 |
Hypoparathyroid therapy
A method for treating hypoparathyroidism and/or hypocalcemia by local administration of a neurotoxin, such as a botulinum toxin, to a parathyroid gland, thereby reducing an inhibitory effect upon...
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6632429 |
Methods for treating pervasive development disorders
A method of utilizing the chymotrypsin level of an individual as a measure of the success of secretin, other neuropeptides, and peptides or digestive enzyme administration to such individuals, and...
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6632446 |
Coating substrates by polymerizing macromers having free radical-polymerizable substituents
Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions...
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6632448 |
Process for producing L-arabinose, L-arabinose-containing enzymatically processed products, diet foods, diabetic diet foods and fruit or vegetable juices and process for producing the same
Processes for conveniently and economically producing L-arabinose, enzyme-treated products containing L-arabinose, diet foods and diabetic foods containing L-arabinose with dietary fiber, and fruit...
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6630003 |
Colouring agents with enzymes
The present invention relates to a composition for coloring keratin fibers containing at least one dye precursor and a choline-based oxidase system. The present invention also relates to a process...
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6627192 |
Use of dual compartment mixing container for enzyme mixtures useful to treat acne
An enzymatic powder (or tablet) is stored in a compartment contained in the closure of a vial. The powder contains enzymes from the enzymatic categories Lipases, Peptidases, Keratinases. The vial...
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6627603 |
Method for releasing an active principle contained a multiple emulsion
A method for the controlled release of an active principle contained in a multiple water-in-oil-in-water emulsion characterized in that the multiple emulsion comprises an invert emulsion Ei with an...
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6623735 |
Vaccine containing a thiol protease
Thiol proteases having Cathepsin 1 type activity are used in the formulation of vaccines for combating helminth parasites. Preferably the protease is derived from a fluke such as Fasciola hepatica.
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6624289 |
Region of factor IXa protease domain that interacts with factor VIIIa and methods therefor
Novel polypeptides or derivatives comprising the factor VIIIa binding site on factor IXa are disclosed. The novel polypeptides or derivatives have anti-coagulation activity. Nucleic acids encoding...
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6623964 |
Method for treatment of an aqueous flux by electropulsation of a field parallel to the flow, pulsation chamber and uses thereof
The invention concerns a method for treating an aqueous flow colonized by cells with a pulsed electric field applied to a flow, characterized in that the applied field is substantially parallel to...
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6623750 |
Enzyme composition adapted for application to ruminant feed to increase protein digestability thereof and method of treating ruminant feeds relating thereto
Enzyme feed supplements containing fungal cellulase produced by Trichoderma viride are specially adapted for increasing protein digestability of dairy cow and cattle feed. Preferred embodiments...
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6617142 |
Method for attachment of biomolecules to medical device surfaces
Methods are provided for forming a coating of an immobilized biomolecule on a surface of a medical device to impart improved biocompatibility for contacting tissue and bodily fluids. A biomolecule...
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6613322 |
Method for treating a subject suffering from conditions associated with an extracellular zinc sphingomyelinase
The present invention provides for a method for treating a subject suffering from a condition associated with an extracellular zinc sphingomyelinase activity which comprises administering to the...
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6613324 |
Adhesive for the gluing of biological tissues
Disclosed is an adhesive for gluing of biological tissue, in particular human body tissue. The adhesive contains fibrinogen, a substance capable of supplying calcium ions, blood-coagulating factor...
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6592866 |
Non-selfdegrading endoprotease
The present invention relates to a novel endoproteolytic hatching enzyme called zonase. The new enzyme is a non-selfdegrading endoprotease. The inventors have purified the enzyme to sequence...
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6592906 |
Anticariogenic dairy product and its use
The invention relates to a food composition containing an effective quantity of rennetted milk for preventing or treating dental caries or dental plaque. The invention also relates to a method of...
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6586390 |
Methods and materials relating to novel prothrombinase-like polypeptides and polynucleotides
The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human prothrombinase-like polypeptide. These...
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6585957 |
Medicinal aerosol formulation
A medicinal formulation is disclosed. The formulation comprises (a) a protein or peptide medicament; (b) a fluid carrier for containing said medicament; and a stabilizer selected from an amino...
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6585970 |
Method for treating hypothyroidism
A method for treating hypothyroidism by local administration of a neurotoxin, such as a botulinum toxin, to a thyroid, thereby reducing an inhibitory effect upon thyroid hormone secretion. A method...
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6579544 |
Method for supplementing the diet
A dietary supplement blend composition is disclosed, the basic formulation of the composition containing vitamins, minerals, and carotenoids. The composition can also contain bioflavonoids,...
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6576444 |
IRAK3 polynucleotides
The invention provides methods and compositions relating to a novel kinase, IRAK3. The polypeptides may be produced recombinantly from transformed host cells from the disclosed IRAK3 encoding...
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6569658 |
Germinal center kinase cell cycle proteins
The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host...
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6562606 |
Methods and compositions for disrupting the epithelial barrier function
A method for disrupting epithelial barrier function in a host in need of the topical administration of a physiologically active substance which comprises applying to the epithelium of the host,...
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6562608 |
Coenzymes useful for the synthesis of L-carnitine
The invention described herein relates to coenzymes useful for the synthesis of L-carnitine, particularly a compound of coenzyme A, and more particularly gamma-butyrobetainyl-coenzyme A and...
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6562580 |
Germinal center kinase cell cycle proteins, compositions and methods of use
The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host...
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6551629 |
Cardiovascular promotion and maintenance composition
The invention relates to a composition for to assist in the achievement of optimal cardiovascular health. The composition addresses various concerns including low antioxidant status, low levels of...
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6551590 |
Hyaluronidase preparation for ophthalmic administration and enzymatic methods for accelerating clearance of hemorrhagic blood from the vireous body of the eye
The invention provide a method for accelerating the clearance of hemorrhagic blood from the vitreous humor of a mammalian eye without producing toxicity to the eye, the method comprising contacting...
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6548080 |
Method for partially demineralized cortical bone constructs
The invention is directed toward a sterile bone structure for application to a bone defect site to promote new bone growth at the site comprising a partially demineralized cortical bone structure,...
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6548556 |
Stable enzymatic wound debrider
This invention relates to an enzymatic anhydrous hydrophilic wound debrider that uses in combination a proteolytic enzyme and an anhydrous hydrophilic poloxamer carrier.
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6544947 |
Compositions and methods for inhibiting endothelial cell proliferation and regulating angiogenesis using cancer markers
Compositions and methods for regulating angiogenic activity wherein the compositions comprise cancer markers including kallikreins such as prostate-specific antigen (PSA), serine protease homologs,...
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6544515 |
Acceleration of the rate of digestion of a protein
The invention thus relates to a method for accelerating the rate of digestion of a protein matter, in which a protein matter is treated with transglutaminase, and it is mixed with anionic...
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6541606 |
Stabilized protein crystals formulations containing them and methods of making them
This invention relates to methods for the stabilization, storage and delivery of biologically active macromolecules, such as proteins, peptides and nucleic acids. In particular, this invention...
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6537588 |
Food-induced antisecretory proteins in egg yolk
The invention generally relates to the use of natural anti-secretory proteins (NASP) for the preparation of NASP-enriched functional food products or pharmaceutical products for the treatment and...
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6537785 |
Methods of treating lysosomal storage diseases
The present invention provides methods of treating lysosomal storage disease with highly phosphorylated lysosomal hyrdrolases.
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6534632 |
Sialidase localized in plasma membrane DNA coding for the same
The present invention provides a protein defined in the following (A) or (B), and DNA coding for the same: (A) a protein which has the amino acid sequence of SEQ ID NO: 2 or SEQ ID NO: 4, or (B) a...
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6531125 |
Antiviral ricin-like proteins
The present invention provides a protein having an A chain of a ricin-like toxin, a B chain of a ricin-like toxin and a heterologous linker amino acid sequence, linking the A and B chains. The...
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6527689 |
Maternally transcribed protein
The invention provides a human maternally transcribed protein (HMTP) and polynucleotides which identify and encode HMTP. The invention also provides expression vectors, host cells, agonists,...
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6528637 |
Fatty acid synthase mRNA binding protein
Disclosed is a 178 kDa glucose-inducible human fatty acid synthase (FAS) mRNA binding protein which has been purified to homogeneity and its binding element characterized. This large phosphoprotein...
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6524578 |
Use of nuclease to reduce wrinkles and discolorations in humans
A method for reducing wrinkles and discoloration on human tissue skin cells which involves forming a nuclease solution and applying the nuclease solution to portions of a subject's body where the...
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6524580 |
Method for treating thyroid disorders
A method for treating hypothyroidism by local administration of a neurotoxin, such as a botulinum toxin, to a thyroid, thereby reducing an inhibitory effect upon thyroid hormone secretion. A method...
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6524579 |
Human RNA binding process
The invention provides human RNA binding proteins (RNABP) and polynucleotides which identify and encode RNABP. The invention also provides expression vectors, host cells, antibodies, agonists, and...
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6514506 |
Whitening compositions containing ascomycete derived enzyme
The present invention relates to topical whitening compositions comprising a whitening effective amount of an Ascomycete-derived melanin-degrading enzyme extract and methods of preparing the...
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6500426 |
Carbohydrate-based enzyme-containing granules for use in animal feed
Enzyme-containing granules for manufacturing animal feed compositions are prepared using a carrier containing at least about 15% (w/w) carbohydrate such as starch and less than 5% (w/w) protein. A...
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6500427 |
One-component tissue adhesive and a process for the production thereof
A description is given of a one-component tissue adhesive containing, in aqueous solution, fibrinogen, F XIII, a thrombin inhibitor, prothrombin factors, calcium ions and, where appropriate, a...
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6500610 |
Methods for identifying compounds for inhibiting of neoplastic lesions, and pharmaceutical compositions containing such compounds
This invention provides pharmaceutical compositions containing compounds for the treatment of neoplasia in mammals. The phosphodiesterase inhibitory activity of a compound is determined along with...
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