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7138103 |
Use of bi-specific antibodies for pre-targeting diagnosis and therapy
The present invention relates to targetable constructs which may be bound by a bi-specific antibody or antibody fragment having at least one arm that specifically binds construct. The targetable...
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7135173 |
Antiviral activity of Shiga toxin
The present invention provides methods and compositions for eliminating virally-infected cells by administering a Shiga-toxin composition, and the present invention provides methods and...
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7132118 |
Cucumis melo extract coated and/or microencapsulated in a fat-soluble agent based on a fatty substance
The present invention relates to a composition comprising an active plant extract containing superoxide dismutase, said extract being coated and/or microencapsulated in a fat-soluble agent based on...
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7132415 |
Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
The present invention provides therapeutic combinations and methods including at least one sterol or 5α-stanol absorption inhibitor that can be useful for treating xanthomas.
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7125689 |
Method for rendering streptokinase less immunogenic to a human
Protein, or parts of proteins, may be rendered non-immunogenic, or less immunogenic, to a given species by identifying in their amino acid sequences one or more potential epitopes for T-cells of...
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7125836 |
Method of cancer screening; method of cancer treatment; and method of diabetes treatment
A method of cancer screening comprising the steps of administering the Blood CA 27,29 testing procedure; if the result is positive administering a mammogram; if the result is positive...
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7125839 |
Anti-pathogen treatments
Chimeric molecules that contain at least one pathogen-detection domain and at least one effector domain, and their methods of use in preventing or treating a pathogen infection in a cell or...
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7122356 |
Method for attachment of biomolecules to medical device surfaces
A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. One method of the present invention includes immobilizing a biomolecule...
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7115260 |
Interleukin-1β converting enzyme like apoptotic protease-6
Human ICE LAP-6 polypeptides and DNA (RNA) encoding such ICE LAP-6 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing...
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7115404 |
UDP-galactose: β-D-galactose-R 4-α-D-galac-tosyltransferase, α4Gal-T1
A novel gene defining a novel enzyme UDP-Galactose: β-D-Galactose-R 4-α-D-galactosyltransferase, termed α4Gal-T1, with unique enzymatic properties is disclosed. The invention discloses isolated...
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RE39321 |
Supplemented and unsupplemented tissue sealants, methods of their production and use
This invention provides a fibrin sealant dressing, wherein said fibrin sealant may be supplemented with at least one composition selected from, for example, one or more regulatory compounds,...
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7101684 |
Modified modular polyketide synthase
Modular polyketide synthases modified so as not to incorporate natural starter units can be used for clean synthesis of novel polyketides.
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7094401 |
HCV core protein binding agents for treatment of hepatitis C virus infection
The present invention provides a method of treating or preventing hepatitis C virus infection in a subject which comprises administering an effective amount of an agent to the subject, wherein the...
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7070773 |
Chemical and/or biological decontamination system
The present invention provides compositions effective in decontaminating either biological pathogens or both chemical and biological pathogens. These compositions are particularly suitable for the...
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7063837 |
Syrup composition containing phage associated lytic enzymes
The present invention discloses a method and composition for the treatment of bacterial infections by the parenteral introduction of at least one lytic enzyme produced by a bacteria infected with a...
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7060263 |
Super absorption Coenzyme Q10
An improved soft gelatin formulation and process methodology that increases single Coenzyme Q 10 molecules presented to the absorption channels of the small intestines by providing medium chain...
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7053042 |
Activation of peptide prodrugs by hK2
The invention provides novel peptide prodrugs that contain cleavage sites specifically cleaved by human kallikrein 2 (hK2). These prodrugs are useful for substantially inhibiting the non-specific...
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7041286 |
Composition for mitigating a pernicious thrombotic event
A composition. The composition comprises aspirin, magnesium, and nattokinase, and either niacin or nitroglycerine. The composition has a structural form of: a chewable form, a dissolvable form, a...
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7037894 |
Stabilized proteins
Isolated polypeptides or polypeptide chains are modified by di-tyrosine cross-linking such that the retain at least one functional activity. In one embodiment, the isolated polypeptide or...
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7037534 |
Inactivation of viral infections agents by chemiluminescence activated light-sensitive compounds
Described herein is an invention that relates to chemiluminescence-directed antiviral activities of natural and synthesized light-sensitive compounds. Methods are described herein for inactivating...
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7033588 |
Preventive agent for ascites in poultry
It is intended to provide a preventive agent for ascites containing coenzyme Q which can sufficiently exert an effect on preventing ascites even when administering in a small dose and within a...
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7034111 |
17867, a novel human aminopeptidase
The present invention relates to a newly identified human aminopeptidase. The invention also relates to polynucleotides encoding the aminopeptidase. The invention further relates to methods using...
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7029672 |
Use of quinone Q10 for the treatment of ocular diseases
The present invention relates to the use of Coenzyme Q 10 or functionally equivalent derivatives thereof, through topical or systemic administration, for the prevention, the treatment and/or...
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7026361 |
Composition comprising ubiquinone
This invention relates to a composition comprising ubiquinone having superior dispersion-stability in an aqueous solution and high bioavailability. The ubiquinone(s) is dispersed and emulsified in...
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7022521 |
Methods and compositions for treating platelet-related disorders using MPL pathway inhibitory agents
The invention relates to the treatment of subjects for the purpose inhibiting vaso-occlusive events, including thrombosis and embolism, by administering agents which reduce the number of...
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7022309 |
Targeting molecule linked to an imaging agent
Targeting molecules are provided for use in delivering imaging agents to epithelial tissue. The targeting molecule comprises a polypeptide that forms a closed covalent loop, contains at least three...
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7018633 |
Selective destruction of cells infected with human immunodeficiency virus
Compositions and methods for selectively killing a cell containing a viral protease are disclosed. The composition is a varient of a protein synthesis inactivating toxin wherein a viral protease...
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7014850 |
Nasal spray for treating streptococcal infections
A nasal spray for treating a streptococcal infection is disclosed. The spray comprises an effective amount of a lysin enzyme genetically coded for by a C 1 bacteriophage capable of infecting a...
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7014863 |
Additive for an animal feed
The present invention relates to the use of a combination of a protease and an inner salt of a quaternary amine carboxylic acid for the preparation of an agent for the treatment and/or prophylaxis...
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7005128 |
Enzyme feed additive and animal feed including it
The use is provided of a composition as a feed additive which comprises one or more endoglucanases, and 0–20% by weight, based upon the content of cellulase proteins in the composition, of a...
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6991792 |
Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase
A vaccine including recombinant vaccinia virus (ATCC VR-1354) having an inserted gene for coding glutamic acid decarboxylase is used for preventing type 1 diabetes mellitus. The glutamic acid...
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6989150 |
Cosmetic preparation of active substances with a synergistically increased radical protection factor
The inventive cosmetic preparation of active substances, as such as well as in combination with other active substances, protects the skin against free radical aggression in a particularly...
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6982083 |
Starch granules containing a recombinant polypeptide of interest, method for obtaining them, and their uses
The present invention relates to starch granules containing a fusion polypeptide between a starch synthase and a recombinant polypeptide of interest, the nucleotide sequences used for obtaining...
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6964763 |
Methods and compositions for inhibiting HIV infectivity and blocking chemokine activity
The present invention relates to a method for suppressing infectivity of HIV which includes contacting the HIV or a cell targeted by HIV with an effective amount of a thrombospondin or a...
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6953571 |
Cosmetic or pharmaceutical composition for topical use to prevent or differ androgenetic alopecia
A cosmetic-pharmaceutical composition for topical use against human alopecia containing a pool of enzymes of the specific hydroxisteroido-dehydrogenase group in the presence of...
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6949371 |
Isolated human drug-metabolizing proteins, nucleic acid molecules encoding human drug-metabolizing proteins, and uses thereof
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present...
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6942858 |
Compositions containing bacteriophages and methods of using bacteriophages to treat infections
Purified, host-specific, non-toxic, wide host range and virulent bacteriophage preparations that are effective in killing bacterial organisms in vivo are disclosed. Also disclosed are compositions...
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6939850 |
Altered human interleukin-1β convertase (ICE), NEDD-2, and C. elegans ced-3 polypeptides and uses therefor
Described herein is the discovery that human interleukin-1β convertase (ICE) is structurally similar to the protein encoded by the C. elegans cell death gene, ced-3. Comparative and mutational...
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6939542 |
Hyaluronidase preparation for ophthalmic administration and enzymatic methods for accelerating clearance of hemorrhagic blood from the vitreous body of the eye
A thimerosal-free hyaluronidase preparation wherein the preferred hyaluronidase enzyme is devoid of molecular weight fractions below 40,000 MW, between 60-70,000 MW and above 100,000 MW. Also...
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6939685 |
Stabilized tetrazolium phenazine reagent compositions and methods for using the same
Stabilized tetrazolium dye-phenazine reagent compositions and methods for their use in the measurement of an analyte in a sample are provided. The subject reagent compositions include: (1) a...
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6936244 |
Use of bacterial phage associated lysing enzymes for treating streptococcal infections of the upper respiratory tract
A composition for treatment of bacterial infections of the eye is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic...
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6930084 |
Treating arthritis with TNF receptor releasing enzyme
The biological effects of the cytokine TNF are mediated by binding to receptors on the surface of cells. This disclosure describes new proteins and polynucleotides that promote enzymatic cleavage...
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6927053 |
Dual component dental composition containing enzyme
A two component desensitizing dentifrice composition is disclosed which comprises a first dentifrice component containing an enzyme such as papain and a second dentifrice component containing an...
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6924117 |
Human RRP sequences and methods of use
Rhomboid Related Proteins (RRPs), involved in the EGFR signaling pathway, are provided. Transgenic, nonhuman mammals containing a transgene encoding an RRP polypeptide or a gene effecting the...
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6923960 |
Antioxidant combination composition and use thereof
An orally or parenterally administrable composition which comprises the following components:
(a) L-carnitine inner salt or a pharmacologically acceptable salt thereof; (b) acetyl L-carnitine...
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6921532 |
Biological Bioadhesive composition and methods of preparation and use
The present invention relates generally to the preparation and use of biological tissue adhesives which rely on combining fibrinogen and thrombin. More particularly, the present invention relates...
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6913917 |
Anti-cocaine catalytic antibody
Disclosed are catalytic antibodies and polypeptides capable of degrading cocaine. Said catalytic antibodies and polypeptides are characterized by the amino acid sequence of their complementary...
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6913744 |
Method and composition for treating prostate cancer
A method of treating prostate cancer in a living mammal includes local administration of a composition that includes a therapeutically effective concentration of collagenase. In one embodiment, a...
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6908628 |
Disinfectant and antiseptic composition
Wide spectrum disinfecting and antiseptic composition for use in the fields of human medicine, veterinary science and industry, characterized because it includes: Hydrogen peroxide, lactic acid...
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6906106 |
Compositions for the skin comprising fibers and ubiquinones and methods of using the same
The present invention relates to a composition for topical application on the skin, comprising fibers and at least one or two or more compounds selected from the group of the ubiquinones and...
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