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5071649 |
Method of preventing blockage in catheters
In accordance with the present invention, a method is provided for preventing blockage of a catheter. The method comprises admixing an effective concentration of a surface-active copolymer to the...
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5069717 |
Antialgal compositions comprising diphenylethers and lysozyme, methods of controlling algae, and coating compositions comprising the antialgal compositions
A synergistic antialgal composition comprising substituted fluoroalkyl diphenylethers and lysozyme in a ratio to each other which exhibits synergism is disclosed. A particularly effective...
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5068227 |
Cyclodextrins as carriers
Cyclodextrins can be coupled to biorecognition molecules such as antibodies. The cyclodextrins so coupled provide a cavity or complexation zone into which active agents such as labels, drugs and...
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5066490 |
Protein crosslinking reagents cleavable within acidified intracellular vesicles
Crosslinking reagents for amino group-containing compounds are provided, which crosslinkers can be cleaved under mildly acidic conditions. The crosslinkers can be used to crosslink biologically...
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5053225 |
Functional organic thin film chemically bonded to biologically active agent
A water-insoluble functional organic thin film comprising a binder selected from the group consisting of a high molecular weight organic compound and a lipid, having contained therein a...
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5019561 |
Treatment of Parkinson's disease with NADPH
Use of the enzyme cofactor NADPH or a salt thereof for the preparation of a medicament suitable for treating Parkinsonism.
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5011686 |
Thrombus specific conjugates
Disclosed is a method of targeting reagents to the locus of a clot, and a family of substances that have affinity for fibrin. The method and substances exploit the discovery that the binding sites...
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5011858 |
Therapy with coenzyme Q.sub.10 of patients having AIDS or other retroviral diseases
Therapy with a pharmaceutical formulation of coenzyme Q 10 (CoQ 10 ) of patients with Acquired Immune Deficiency Syndrome, known by the acronym AIDS and of patients with other retroviral diseases...
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4976949 |
Controlled release dosage form
A dosage system for administering drugs and conducting gastric flow studies is configured in the form of a multiplicity of substantially spherical subunits which have advantageously preselected...
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4975278 |
Antibody-enzyme conjugates in combination with prodrugs for the delivery of cytotoxic agents to tumor cells
This invention relates to a novel method for the delivery of cytotoxic drugs to tumor cells by the administration of a tumor-specific antibody-enzyme conjugate that binds to the tumor cells, and...
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4970200 |
Agent for treatment of Parkinson's disease
The enzyme cofactor nicotinamide adenine dinucleotide or a salt thereof is useful for the treatment of Parkinson's disease.
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4959212 |
Oxidizing-energizing composition and method for the treatment of diabetes
A non-toxic, oxidizing-energizing composition suitable for use as an accelerator of the carbohydrate oxidative degradation metabolic process or the direct oxidation of glucose which consists...
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4957740 |
Composition for preventing or alleviating skin irritation by formulations containing superoxide dismutase
This invention discloses use of superoxide dismutase (SOD) as an agent for the protection of the skin against inflammatory reactions associated with chemical irritation and acne. Topical...
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4933165 |
Coenzyme Q.sub.10 with HMG-CoA reductase inhibitors
A pharmaceutical composition and method of counteracting HMG-CoA reductase inhibitor-associated myopathy is disclosed. The method comprises the adjunct administration of an effective amount of a...
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4929437 |
Coenzyme Q.sub.10 with HMG-CoA reductase inhibitors
A pharmaceutical composition and method of counteracting HMG-CoA reductase inhibitor-associated elevated transaminase levels is disclosed. The method comprises the adjunct administration of an...
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4921841 |
Immunoaffinity purification of phytolaccin proteins and their use in treating Herpes Simplex virus type II
Antiviral proteins phytolaccin 1 and phytolaccin 2 were isolated from the higher plant Phytolaccin americana using the technique of immunoaffinity chromatography. Phytolaccin proteins were...
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4906457 |
Compositions and methods for reducing the risk of sunlight and ultraviolet induced skin cancer
Compositions and methods for reducing the risk of skin cancer. The novel compositions include at least one effective protease inhibitor. Preferred protease inhibitors include serine protease...
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4904469 |
Therapeutic agents for enzymatic wound cleaning
The invention relates to a wound covering made from a polysaccharide base, particularly cellulose, which is formed as a fabric, which has a high absorbency due to its sponge-like structure and...
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4895724 |
Chitosan compositions for controlled and prolonged release of macromolecules
Compositions for the controlled and prolonged release of macromolecular compounds comprise a porous matrix of chitosan having dispersed therein the macromolecular compound. Examples of...
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4889808 |
Method of enchancing t-PA and SCU-PA production
Disclosed herein is a method of enhancing the production of tissue plasminogen activator (t-PA) and single chain urokinase plasminogen activator (SCU-PA) by normal human lung diploid fibroblast...
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4885164 |
Aqueous protein solutions stable to denaturation
What are disclosed are a method for preventing the denaturation of proteins such as insulin in aqueous solution at interfaces by the addition to the solution of a surface-active substance...
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4885167 |
Restoration of impaired cardiac function of patients with diverse muscular dystrophies by therapy with coenzyme Q10
The present invention relates to the use of Coenzyme Q in the treatment of slow muscle degeneration, commonly known to those of skill in the art so a dystrophy or atrophy, and the accompanying...
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4883670 |
Cosmetic preparations containing ubidecarenones
Ubidecarenones are effectively dissolved in an aqueous medium using N-acyl-2 amino-ethanesulphonates in which the acyl residue has more than 5 carbon atoms. Cosmetic compositions containing...
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4882359 |
Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparations containing the absorption promoters
An azacycloalkane derivative useful for promoting the absorption of a medicine, an absorption promoting agent comprising at least one of the azacycloalkane derivatives as the effective ingredient...
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4876241 |
Stabilization of biological and pharmaceutical products during thermal inactivation of viral and bacterial contaminants
A method of inactivating pathogens in proteinaceous biological and pharmaceutical products which comprises: mixing the product in an aqueous solution with one or more primary stabilizers selected...
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4874742 |
Synthetic whole blood and a process for preparing the same
A composition and a method of making a whole blood substitute are disclosed. The claimed invention duplicates the two phase heterogeneous physico-chemical system of natural whole blood and...
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4869900 |
Pharamaceutical composition containing ubidecarenone
A pharmaceutical composition, comprising: Coenzyme Q 10 (ubidecarenone) 2-17% by weight; Lecithin 50-70% by weight; Surfactant agent 20-48% by weight. The surfactant agent has a melting point...
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4857319 |
Method for preserving liposomes
A method for preserving liposomes includes freeze-drying liposomes most preferably having an average size of about 50 nm to 100 nm with a disaccharide preserving agent being present both internally...
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4849218 |
Oral garlic preparations and process for preparing same
Oral garlic preparations contain garlic powder as well as the enzyme allinase, in which each of the components is spatially separated from the other and are recombined only after having been orally...
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4847082 |
Method of treatment of Alzheimer's disease using phytic acid
A method is provided for treating Alzheimer's Disease by administering to a subject an effective symptom-alleviating amount of a compound selected from the group consisting of phytic acid, phytate...
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4837022 |
Composition containing tissue plasminogen activator
A composition containing a tissue Plasminogen Activator (tPA) which comprises a partial hydrolyzate of gelatin cross-linked to a diisocyanate as an essential ingredient; or alternatively a partial...
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4824938 |
Water-soluble dry solid containing proteinaceous bioactive substance
Proteinaceous bioactive substances (including lymphokine and peptide hormone) in dry solid are extremely stabilized by the presence of the specific polysaccharide mainly composed of repeating...
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4824432 |
Method for treating AIDS and other immune deficiencies and immune disorders
Methods are provided for the treatment of pathological conditions connected with the production of interferons which destroy the immune system and possess damaging action on the cell system of...
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4824669 |
Formulations of coenzyme Q.sub.10 for intravenous use
The present invention comprises a stable and non-toxic coenzyme Q 10 formulation suitable for intravenous administration to an animal to produce clinically effective blood levels of coenzyme Q 10...
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4818763 |
Biologically active substance with hormonal properties, production process thereof and utilization of histones for medical purposes
Biologically active substance with standardizable hormonal activity, containing in a physiological medium at least one histone, particularly at least one histone H2 or an active area of said...
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4772548 |
Radioisotopicassay using isotope transfer to chelator-target recognition molecule conjugate
A method of forming a therapeutic or diagnostic agent labeled with a radioactive metal ion, which comprises: contacting an unlabeled therapeutic or diagnostic agent, consisting of a substantially...
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4767624 |
Decubital remedy
A decubital remedy suitable for cutaneous administration contains ubidecarenone as an effective ingredient. The decubital remedy, which may preferably take the form of a cream, lotion or ointment,...
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4767620 |
Crosslinked polymers with carbonate ester groups, and a process for their preparation
Crosslinked polymers which are produced from monomers containing glycerol carbonate groups, crosslinking monomers and, where appropriate, other monoethylenically unsaturated monomers are composed...
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4738955 |
Anti-carcinoma therapeutic agent of glycosaminoglycans and cytostatic agents
A combination consisting of a mixture comprising high-molecular and low-molecular glycosaminoglycan polysulfates as well as a cytostatic agent is effective to obtain improved results in selectively...
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4737363 |
Bacteroides nodosus vaccine
A vaccine for use in the prevention or treatment of foot-rot comprises an immunologically effective amount of at least one protease, particularly an extracellular serine protease, of Bacteroides...
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4734279 |
Combination of immunoglobulins with therapeutic agents
A compositon for treating diseases which comprises a therapeutically effective amount of an antibacterial, antiviral, or antimycotic agent, antitrypsin, antithrombin, interferon, or lysozyme, and...
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4707360 |
Vasculoprotecting pharmaceutical compositions
Pharmaceutical compositions having vasculoprotecting activity, containing an ubiquinone compound together with one or more compounds of flavanoid, heparinoid, terpenic or glycosidic structure, such...
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4687664 |
Method of inactivating reproducible pathogens
There is described a method of inactivating reproducible pathogens in preparations containing plasmatic enzymes and proenzymes, activated or non-activated coagulation factors, such as Factors II,...
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4684520 |
Pharmaceutical compositions having cerebral antianoxic and metabolic activities
The invention relates to novel pharmaceutical compositions containing ubiquinone, particularly Coenzyme Q 10 , and mixtures of phospholipids having organic or vegetal origin, in weight-ratios...
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4678668 |
Method of reducing soft tissue swelling and pain
Disclosed is a composition and a method for reducing soft tissue swelling and pain. A composition comprising of proteolytic enzyme and a transfer vehicle is topically applied to the injured bodily...
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4670014 |
Implantable, biocompatible reservoirs permitting conservation, cellular culturing, or controlled liberation of an active principle
Biocompatible reservoirs are constituted by collagen, optionally associated with mucopolysaccharides and/or gelatin; these reservoirs can be filled with an active principle which does not have to...
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4668513 |
Method for combating snoring
A method for overcoming snoring is disclosed. A composition is used containing a surface active substance, a preserving agent and/or a substance acting bactericidally or fungicidally on the mucous...
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4617187 |
Therapeutic method for treating radiation ulcers
Cutaneous administration of ubidecarenone, for example, application of ubidecarenone in the form of an ointment has been proven to be effective for treatment of various skin disorders caused by...
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4599232 |
Pharmaceutical composition with metabolic and energetic activity for the use in cardiac and vascular therapy
The invention relates to a pharmaceutical composition containing carnitine or acetylcarnitine and Coenzyme Q 10 in ratios from 100:1 to 2:1, together with pharmaceutically acceptable eccipients....
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4568544 |
Aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method
An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration which comprises an aqueous medium and, dissolved therein, a high purity tissue plasminogen...
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