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9040038 Modalities for the treatment of degenerative diseases of the retina  
This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment...
9040039 Modalities for the treatment of degenerative diseases of the retina  
This invention relates to methods for improved cell-based therapies for retinal degeneration and for differentiating human embryonic stem cells and human embryo-derived into retinal pigment...
9034315 Cell-charged multi-layer collagen membrane  
A multi-layer sheet of collagen membrane material includes a barrier layer including an outer smooth barrier face and further including a fibrous face opposite the smooth barrier face, and a...
9034316 Infarct area perfusion-improving compositions and methods of vascular injury repair  
The described invention provides pharmaceutical compositions for treating an infarct area injury and methods of treating or repairing the infarct area injury in a revascularized subject in the...
9028811 Methods for promoting HSC self-renewal  
The present invention provides for compositions and methods for modulating hematopoetic stem cell populations by using HCS modulators, which are agents that either increase HSC numbers or decrease...
9028526 Method and system for preparing soft tissue for grafting, enhancing grafting results, and grafting autologous fat and adipocyte derived stem cells to soft tissue such as the breast and other tissue defects  
A method is disclosed for preparing a soft tissue site, and augmenting the soft tissue site, such as the breast(s), scar, depression, or other defect, of a subject through use of devices that...
9028810 Composition for inducing migration of neural stem cells containing periostin as effective ingredient  
A novel use of periostin, and more particularly a composition for inducing the migration of neural stem cells, which contains periostin or a periostin-secreting cell as an active ingredient, based...
9029139 Omentum as a source of stromal/stem cells and medical treatment using stromal/stem cells  
Methods for generating and using omentum cells, and particularly stromal cells and/or omentum stem cells, in medical treatments such as tissue repair and regeneration to facilitate healing from...
9023341 Amphiphilic chitosan nanogel as an injectable delivery system for stem cell therapy  
The present invention relates to a novel injectable delivery system for stem cell therapy, which comprises a thermo-sensitive amphiphlic chitosan nanogel. Therefore, the invention provides a...
9023342 Tissue grafting method  
The tissue grafting method relates to a tissue graft material, a method of preparing the material, and a method of using the material. The tissue graft material is made from the tunica serosa of...
9023340 Wnt inhibitors for human stem cell differentiation  
Methods and small molecule compounds for stem cell differentiation and treatment of animals with diseases are provided. One example of a class of compounds that may be used is represented by the...
9018163 Modulating PDX-1 with PCIF1, methods and uses thereof  
This invention relates to PCIFl and its use as a target for the improvement of pancreatic islet β cell mass and function in diabetes. Specifically, the invention relates to the use of compounds...
9017661 Cardiac repair by reprogramming of cardiac fibroblasts into cardiomyocytes  
The present invention involves the use of transcription factors including Tbx5, Mef2C, Hand2, myocardin and Gata4 to reprogram cardiac fibroblasts into cardiomyocytes, both in vitro and in vivo....
9017710 Injectable and swellable microspheres for tissue bulking  
The present invention relates to injectable compositions comprising biocompatible, swellable, hydrophilic, non-toxic and substantially spherical microspheres useful for tissue bulking. The...
9017663 Pluripotent stem cells obtained from dental pulp  
The present invention relates to pluripotent stem cells obtained from the dental pulp of patients of different ages, the invention furthermore comprises cultures of said cells, means for obtaining...
9018237 Methods for improved wound closure employing olivamine and endothelial cells  
The present disclosure relates to compositions for and methods of improving wound healing, including compositions for and methods of treating chronic wounds, and compositions for the inhibition...
9011840 Activated mesenchymal stem cells for wound healing and impaired tissue regeneration  
Inflammatory cytokines e.g. IFN-γ, serve as initiating stimuli for mesenchymal stem cell (MSC) immunosuppresive activity in vivo. Other inflammatory cytokines, such as TNF alpha, the molecule...
9012222 Native wharton's jelly stem cells and their purification  
Noncultured Wharton's Jelly stem cells and methods of their purification, storage and use are provided.
9011837 Tissue-engineered endothelial and epithelial implants repair multilaminate tubular airway structure  
Endothelial implants restore vascular homeostasis after injury without reconstituting vascular architecture. Endothelial cells line the vascular epithelium and underlying vasa vasorum precluding...
9011895 EB matrix production from animal tissue and its use for tissue repair  
A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue to chemical and mechanical processing. In addition to skin tissue, another source of...
9005960 Functionalized membrane for a chamber for encapsulating cells producing at least one substance of therapeutic interest and bioartificial organ comprising such a membrane  
The present invention relates to a functionalized semi-permeable membrane composed of a porous biocompatible support pretreated so as to increase the surface energy thereof and characterized in...
9005604 Aligned and electrospun piezoelectric polymer fiber assembly and scaffold  
A scaffold assembly and related methods of manufacturing and/or using the scaffold for stem cell culture and tissue engineering applications are disclosed which at least partially mimic a native...
9005885 Bioartificial lung  
Presented is an airway organ bioreactor apparatus, and methods of use thereof, as well as bioartificial airway organs produced using the methods, and methods of treating subjects using the...
9005607 Stem cell culture method  
Methods for culturing pluripotent stem cells on fiber scaffolds are provided which result in the expansion of the number of stem cells without loss of pluripotency. Cells obtained by such methods,...
9005648 Inorganically surface-modified polymers and methods for making and using them  
In alternative embodiments, the invention provides articles of manufacture comprising biocompatible nanostructures comprising PolyEther EtherKetone (PEEK) surface-modified (surface-nanopatterned)...
9005605 Compositions and soft tissue replacement methods  
The specification discloses compositions and methods for treating a soft tissue defect of an individual.
9005606 Silk fibroin hydrogels and uses thereof  
The present specification provides for methods for purifying fibroins, purified fibroins, methods of conjugating biological and synthetic molecules to fibroins, fibroins conjugated to such...
8999378 Porous electroactive hydrogels and uses thereof  
The present invention provides porous electroactive hydrogels, the deformation angle of which is controlled by electroactuation, and methods for preparing and using such hydrogels.
8992906 Compositions and methods for engraftment and increasing survival of adult muscle stem cells  
Embodiments herein relate to compositions and methods for engraftment of and increasing survival of muscle cells in a subject in need thereof. In certain embodiments, compositions including...
8992613 Unshrunken tissue equivalent and methods for producing such an unshrunken tissue equivalent  
The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular...
8986676 MNTF differentiation and growth of stem cells  
The present invention provides methods for inducing differentiation of an embryonic stem cell into a motor neuron using a motoneuronotrophic factor (MNTF) or its peptide analogs. The present...
8986678 Preparation of parental cell bank from foetal tissue  
The present invention relates to methods of in vitro preparation of a parental cell bank (PCB) from foetal tissue consisting of foetal epiphyseal tissue, foetal Achilles tendon tissue and foetal...
8986679 Somatic stem cells  
A method of treating a cellular proliferative disorder in a subject by obtaining from a subject a bodily fluid sample containing a plurality of cells, incubating the sample with EDTA or heparin in...
8986677 Therapeutic compositions and methods  
This invention relates to the use of cortisol blockers (glucocorticoid receptor [GR] antagonists) for the prevention of addiction induced anxiety and withdrawal side effects as a therapeutic and...
8980248 Injectable polymer composition for use as a cell delivery vehicle  
This invention provides a polymer composition comprising at least one thermal gelling polymer and at least one anionic polymer for cell delivery applications. These injectable polymer compositions...
8980250 Use of des-aspartate-angiotensin I in inflammation-related pathologies and diseases  
The present disclosure generally relates to the use of des-aspartate-angiotensin I and/or its derivatives in medicine. In particular, the present invention relates to the use of...
8980301 Multilayered blood product  
A blood product (10), a method for preparing the blood product, a blood product obtainable by the method and a blood product preparing container means. The blood product comprises components from...
8980251 Methods for preventing and treating hemorrhoids  
The invention is directed to methods for treating hemorrhoids. The invention is also directed to methods for preventing hemorrhoids. The invention is further directed to reducing inflammation...
8980249 Agonists of growth hormone releasing hormone as effectors for survival and proliferation of pancreatic islets  
Agonists of growth hormone releasing hormone promote islet graft growth and proliferation in patients. Methods of treating patients comprise the use of these agonists.
8975231 Bone morphogenic protein binding peptide  
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2, as do endogenous forms of BBP, and sequence conservation between species results in a...
8974810 Tissue graft compositions and methods for producing same  
A tissue graft composition is described herein that includes a segment of small intestinal submucosa having at least one nanoparticle incorporated therein such that the permeability of the segment...
8975075 Hemostatic device  
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
8974779 Disease treatment via developing non-syngeneic graft transplantation  
A method of providing a pancreatic, lymphoid/hematopietic or pulmonary organ and/or tissue function to a mammalian subject is provided. The method comprises transplanting into the subject a...
8968725 Genipin cross-linked fibrin gels  
The invention provides a genipin cross-linked fibrin gel. The ratio of genipin to fibrin in the gel ranges from about 0.1:1 to about 10:1 (genipin:fibrin). The gel can be hydrogel. Also provided...
8968724 Compositions suitable for treatment of spinal disease, disorder or condition  
The invention relates to the use of viral inactivated-plasma cryoprecipitate concentrate (VIPCC) comprising a suitable fibronectin/fibrinogen ratio for treating a spine disease, disorder or...
8961955 Maintenance and propagation of mesenchymal stem cells  
Various embodiments of the present invention include compositions, materials and methods for maintaining and propagating mammalian mesenchymal stem cells in an undifferentiated state in the...
8961956 Mesenchymal stromal cells and uses related thereto  
The present invention generally relates to novel preparations of mesenchymal stromal cells (MSCs) derived from hemangioblasts, methods for obtaining such MSCs, and methods of treating a pathology...
8961954 Muscle derived cells for the treatment of urinary tract pathologies and methods of making and using the same  
The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction...
8951513 Methods and apparatus for enhanced recovery of cells and of cell-enriched matrix from tissue samples  
This document describes methods and an apparatus for recovery of a cell-enriched matrix and cells (e.g., regenerative cells) from a tissue sample. In some embodiments, at least two rounds of...
8951793 Method of making an isolated population of FOXP3+ regulatory T cells  
Disclosed are methods of isolating and using a population of FOXP3+ regulatory T cells in a variety of preventative and therapeutic approaches to autoimmune diseases, graft-versus-host disease and...