|
Match
|
Document |
Document Title |
|
|
7166277 |
Remyelination of neurons using multipotent neural stem cell progeny
The invention provides methods for producing myelin forming cells from multipotent self-renewing central nervous system neural stem cells as well as methods of using one or more cells from a...
|
|
|
7163920 |
Peptide with osteogenic activity
The present invention provides a composition including an isolated or recombinant peptide component that has osteogenic cell proliferative activity. The peptide, which promotes proliferation of...
|
|
|
7160719 |
Bioartificial liver system
A bioartificial liver system is described that incorporates a cell reservoir and hepatocyte spheroids to both increase the number of and longevity of cells in the system. Additional methods are...
|
|
|
7157080 |
Injectable hyaluronic acid derivative with pharmaceuticals/cells
Disclosed is an injectable, biocompatible and biodegradable composition, comprising at least one hyaluronic acid benzyl ester or auto-cross-linked derivative, in combination with at least one...
|
|
|
7153519 |
Implantable substrate coated with a macromer having free radical polymerizable substituents
Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions...
|
|
|
7144730 |
Lipoxygenase proteins and polynucleotides encoding the same
The nucleotide and corresponding amino acid sequences are reported for a novel class of mammalian lipoxygenase proteins. The novel lipoxygenase encoding polynucleotides were obtained from human...
|
|
|
7144575 |
Methods for selectively stimulating proliferation of T cells
Methods for inducing a population of T cells to proliferate by activating the population of T cells and stimulating an accessory molecule on the surface of the T cells with a ligand which binds the...
|
|
|
7138275 |
Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
The invention relates to the production of adult dedifferentiated, programmable stem cells from human monocytes by cultivation of monocytes in a culture medium which contains M-CSF and IL-3. The...
|
|
|
7135172 |
Bucky paper as a support membrane in retinal cell transplantation
A method for repairing a retinal system of an eye, using bucky paper on which a plurality of retina pigment epithelial cells and/or iris pigment epithelial cells and/or stem cells is deposited,...
|
|
|
7135171 |
Endothelial precursor cells for enhancing and restoring vascular function
The invention provides methods of treating and preventing loss of tissue vascularization that can occur, for example, upon aging.
|
|
|
7132285 |
Apoptotic entities for use in treatment of neurodegenerative and other neurological disorders
Treatment and/or prophylaxis, in mammalian patients, of neurodegenerative and other neurological medical disorders is effected by administering to the patient effective amounts of apoptotic bodies...
|
|
|
7122179 |
Live genetically attenuated malaria vaccine
Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a gene whose expression is up-regulated...
|
|
|
7122200 |
Vitro engineered, regenerated urinary tract tissue compositions and methods for producing same
A method for providing a urinary tract tissue graft composition includes providing a tissue culture frame and a segment of small intestinal submucosa and positioning the segment of small intestinal...
|
|
|
7122208 |
Compositions containing apoptotic entities
Disclosed are methods for treating and preventing neurological disorders which have a significant inflammatory component. The methods of the present invention involve extracting blood from a...
|
|
|
7118924 |
Method for producing human antibodies in SCID mice which uses dendritic cells pulsed with antigen-antibody complexes and antigen-antibody complexes as immunizing agents
An improved method for producing human antibodies in SCID mice is provided. The improvement includes the use of dendritic cells pulsed with antigen-antibody complexes and antigen-antibody complexes...
|
|
|
7115562 |
Peptides and their use to ameliorate cell death
The present invention relates to a method of reducing cell death in a warm-blood animal wherein said cell death associated with a neurodegenerative disorder, an immune disease, a neoplastic...
|
|
|
7112653 |
Composition and method for preserving progenitor cells
The invention relates to a protein material which is effective to preserve progenitor cells, such as hematopoietic progenitor cells. The protein has an amino acid sequence comprising AQSLSFSFTKFD...
|
|
|
7109026 |
Use of MHC class II ligands as adjuvant for vaccination and of LAG-3 in cancer treatment
The present invention concerns a use of a MHC class II ligand, such as CD4 and LAG-3, for the manufacture of a medicament for preventing or treating pathological conditions involving an antigen...
|
|
|
7105155 |
Method and activated lymphocyte preparations for preventing recurrence of carcinoma
Activated lymphocytes are administered to a cancer patient at least five or more times within eight months after performing surgical and chemotherapeutic treatment or radiotherapy for treating...
|
|
|
7101545 |
Method for using human intervertebral disc cells
There is provided a method for growing human intervertebral cells. Disc tissue is surgically removed from a normal disc of a patient, the cells expanded by feeding with a cell stimulant such as a...
|
|
|
7101546 |
In situ maturation of cultured pancreatic stem cells having a specified, intermediate stage of development
This invention relates to the discovery that an intermediate, differentiated stage of pancreatic stem cells exist that can be matured in situ into a stable cell line that produces insulin in...
|
|
|
7098027 |
Method for remyelinating a demyelinized lesion due to injury in the brain or spinal cord
Demyelinated axons were remyelinated in the demyelinated rat model by collecting bone marrow cells from mouse bone marrow and transplanting the mononuclear cell fraction separated from these bone...
|
|
|
7097833 |
Selected cell delivery for heart failure
This invention provides methods of increasing blood flow to tissue in a subject in need thereof, methods of regenerating tissue in a subject, methods of treating diseased tissue in a subject,...
|
|
|
7097832 |
Intramyocardial injection of autologous bone marrow
A method of treating cardiac or myocardial conditions comprises the administration of an effective amount of autologous bone marrow. The bone marrow may optionally be stimulated and/or administered...
|
|
|
7087371 |
Material and methods for the production of sperm and analysis thereof
Provided herein are methods of producing viable sperm from neonatal mammalian testes which have been engrafted in mice.
|
|
|
7087227 |
Cartilage composites and methods of use
Disclosed are neocartilage compositions characterized by having multiple layers of cells, said cells being surrounded by a substantially continuous insoluble glycosaminoglycan and collagen-enriched...
|
|
|
7078232 |
Adipose tissue-derived adult stem or stromal cells for the repair of articular cartilage fractures and uses thereof
The invention provides cells, methods and compositions based upon the use of adipose tissue-derived adult stem cells in the repair of articular cartilage fractures or defects. The invention is...
|
|
|
7078033 |
Urinary tract tissue graft compositions and methods for producing same
A method for repairing damaged or diseased urinary tract tissue includes providing a urinary tract tissue graft composition that includes a distal ileal segment of small intestinal submucosa. The...
|
|
|
7074552 |
Method of forming vascularized kidney tissue
A method for constructing a stable bioactive mammalian embryonic kidney is described herein. A kidney so constructed requires no artificial support, nor porous man made membranes or tubing to...
|
|
|
7074762 |
Composition and method for improving function of embryonic kidney transplants
A method and composition for enhancing the development of metanephric tissue upon transplantation into an allogenic or xenogenic host are disclosed. Metanephric tissue is removed from an embryonic...
|
|
|
RE39172 |
Method for preparing two-layer bicomposite collagen material for preventing post-operative adhesions
A bicomposite material based on collagen is prepared which has two closely bound layers and is biocompatible, non-toxic, hemostatic and biodegradable in less than a month, and can be used in...
|
|
|
7070771 |
Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
This invention relates to genes which encode accessory molecule ligands, such as the CD40 ligand and their use for immunomodulation, vaccination and treatments of various human diseases, including...
|
|
|
7067123 |
Glue for cartilage repair
The invention is directed toward a sterile cartilage defect implant material comprising milled lyophilized allograft cartilage pieces ranging from 0.01 mm to 1.0 mm in size in a bioabsorbable...
|
|
|
7063855 |
Composition for feeding prey organisms in aquaculture
A composition is for feeding aquacultural prey organisms such as Artemia and rotifiers, comprising a lipid component comprising at least 25 wt % of phospholipids and providing a DHA content of at...
|
|
|
7056503 |
Enclosures housing cell-coated supports for treating tumors
The present invention relates to devices, systems and methods for treating tumors. In particular, the present invention relates to enclosures housing cell-coated supports for promoting regression...
|
|
|
7056726 |
membrane for encapsulation chamber of cells producing at least a biologically active substance and bioartificial organ comprising same
The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate...
|
|
|
7056501 |
Recombinant neospora antigens and their uses
The present invention provides isolated bovine Neospora cultures. Also provided are recombinant immunodominant Neospora antigens. The cultures and antigens are used to develop diagnostic assays...
|
|
|
7052694 |
Dendritic cell potentiation
A molecule capable of potentiating immune responses is described, as well as methods for using the molecule to enhance immune responses and enhance dendritic cell function. Also described are...
|
|
|
7048922 |
Stimulation of hematopoiesis by ex vivo activated immune cells
A protocol of activating and administering human blood cells so that bone marrow histology and/or blood cell counts of patients suffering from aplastic anemia approach normal. The protocol includes...
|
|
|
7045125 |
Biologically active composites and methods for their production and use
Biologically active composites containing calcium phosphate, more specifically beta-tri-calcium phosphate, and methods of preparing the same are disclosed herein. Also disclosed are methods of...
|
|
|
7045124 |
Pre-conditioning against cell death
Apoptosis and/or necrosis related disorders in the mammalian body, namely radiation exposure disorders, chemical exposure and ingestion disorders, neurological disorders and physical trauma...
|
|
|
7045148 |
Method of collecting placental stem cells
A method of collecting embryonic-like stem cells from a placenta which has been treated to remove residual cord blood by perfusing the drained placenta with an anticoagulant solution to flush out...
|
|
|
7045502 |
Use of melagatran for the manufacture of a medicament for the treatment of Type 1 diabetes mellitus
According to the invention there is provided the use of melagatran, or a pharmaceutically-acceptable derivative thereof, for the manufacture of a medicament for the treatment of Type I diabetes.
|
|
|
7041634 |
Method of inhibiting immune system destruction of transplanted viable cells
This invention provides a method of inhibiting viable cells transplanted into a subject from being destroyed by the subject's immune system which comprises: a) containing the viable cells, or...
|
|
|
7041283 |
Methods of using immunophilin binding drugs to improve integration and survival of neuronal cell transplants
A method of treatment of neurodegenerative diseases using neuronal cell transplants is provided. The growth, survival and integration of the transplanted neuronal cells is enhanced by a method of...
|
|
|
7041504 |
Cancer cell-inhibiting culture medium produced by culturing restricted entrapped cancer cells
Compositions of matter are described which contain restricted cancer cells. When so restricted, the cells produce an unexpectedly high amount of material which suppresses cancer cell proliferation....
|
|
|
7033832 |
Endothelial cell—cell cohesion
Methods for stably populating solid surfaces, especially those of biomedical devices, with cells; also the resulting cell-coated surfaces.
|
|
|
7033587 |
Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
Methods and compositions for directing adipose-derived stromal cells cultivated in vitro to differentiate into cells of the chondrocyte lineage are disclosed. The invention further provides a...
|
|
|
7029689 |
Tubular construct for implantation
The present invention is directed to devices for repair, replacement or augmentation of soft tissues in an organism. The devices comprise cellular compositions comprising cells and preferably,...
|
|
|
7029671 |
Method for activating human antigen-presenting cells, activated human antigen-presenting cells, and use thereof
The invention relates to a method for activating human-derived antigen-presenting cells by in vitro cultivation with at least one of the glycoside compounds represented by formula (A) or salts...
|