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8182806 |
Synovial villi for use with tissue engineering
Synovial villi derived explants and related surgical tools used to repair or prevent damage to injured or diseased tissue, including connective tissue. The tools including a harvesting tool for...
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8178089 |
Neuronal progenitors from feeder-free human embryonic stem cell culture
The present invention relates to methods for producing feeder cell-free neuroprogenitor cells (preferably adherent) from embryonic stems cells, preferably human embryonic stem cells, the feeder...
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8178085 |
Methods of proliferating stem cells
The invention relates to methods of proliferating stem cells. More particularly, the invention relates to the use of glycosaminoglycans or proteoglycans to promote the growth of stem cells in ex...
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8178084 |
Pharmaceutical kits comprising mesenchymal stem cells
A method of treating a natural soft skeletal tissue injury in a patient the method comprising administering to the patient a composition of mesenchymal stem cells in liquid suspension enriched...
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8173119 |
Use of adipose-tissue cell fractions for post-irradiation tissue regeneration
The present invention concerns the use of cells derived from the cellular fraction of the vascular stroma of the extramedullary adipose tissue to promote the regeneration of tissue following...
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8168174 |
Method of isolating human neuroepithelial precursor cells from human fetal tissue
A method for isolating human neuroepithelial precursor cells from human fetal tissue by culturing the human fetal cells in fibroblast growth factor and chick embryo extract and immunodepleting from...
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8168166 |
Live genetically attenuated malaria vaccine
Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
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8168173 |
CerCan: an energy supplement product for boosting the immune system
This invention concerns the process of creating an energy supplement product, good also as an anti-aging, aphrodisiac and as an alternative source to prevent or to remedy some diseases. The product...
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8161904 |
Direct coating solid dosage forms using powdered materials
The present invention provides a method and apparatus for dry coating solid dosage forms. The method includes the steps of placing solid dosage forms in a rotatable, electrically grounded housing,...
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8163276 |
Systems and methods for isolating and using clinically safe adipose derived regenerative cells
Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g.,...
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8158119 |
Cardiac targeted delivery of cells
A method of delivering cardiac stem cell and treating damaged cardiac tissue is provided. The method involves isolation of subject's cardiac circulation from the subject's systemic circulation and...
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8158120 |
Cardiac muscle repair or regeneration using bone marrow-derived stem cells
Disclosed are compositions and methods for repairing and/or regenerating cardiac tissue by administering adult bone marrow-derived stem cells to an individual. These cells can be administered as a...
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8158122 |
Mixed cell populations for tissue repair and separation technique for cell processing
The present invention provides a fluid exchange cell culture technique and tissue repair cells (TRCs) made by these methods, as well as methods using these cells. The method includes a new wash...
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8158121 |
Cardiac muscle regeneration using mesenchymal stem cells
Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered...
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8153158 |
Tissue substitutes comprising stem cells and reduced ceria
A biocompatible composite includes a solid biocompatible material and a plurality of living human progenitor or living stem cells attached thereto. The composition resulting in accelerated repair...
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8153147 |
Heparin coating of biological tissue
The present invention discloses an in vitro method to provide biological tissue with a heparin coating comprising the following steps; linking a biotin reagent to biological tissue, linking an...
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8148150 |
Method for the production of intervertebral disk cell transplants and their use as transplantation material
The invention relates to a method for the in vitro production of intervertebral disk cartilage cell transplants from affected intervertebral disk tissue from patients and to the use thereof as...
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8147824 |
Immunomodulatory properties of multipotent adult progenitor cells and uses thereof
Isolated cells are described that are not embryonic stem cells, not embryonic germ cells, and not germ cells. The cells can differentiate into at least one cell type of each of at least two of the...
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8146602 |
Method and mixture for nerve root repair
The invention provides a method of functionally connecting a portion of the peripheral nervous system of a vertebrate to a portion of the central or peripheral nervous system of said vertebrate,...
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8142774 |
Methods of treatment using electromagnetic field stimulated stem cells
Methods of modifying stem cells and compositions of modified stem cells, in particular mesenchymal stem cells, using electric or electromagnetic fields. In various embodiments, the present...
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8143042 |
Biodegradable elastomers
The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a...
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8143043 |
Encapsulated cells using positively-charged initiator polymer
Positively-charged initiator polymers having a polymerization initiator group and a cationic portion are provided. The initiator polymers can be used with a polymerizable material for the formation...
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8142773 |
Methods of implanting mesenchymal stem cells for tissue repair and formation
The invention relates to methods of isolating and implanting mesenchymal stem cells for tissue repair or formation, without prior culture expansion of the mesenchymal stem cells. In particular, the...
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8137665 |
Systemic non-nodular endosymbiotic nitrogen fixation in plants
Non-leguminous crops, e.g. wheat, maize and rice, do not form nodules and are dependant for their nutrition on fixed nitrogen from the soil, or from chemical/nitrogenous fertilizers. The present...
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8137408 |
Autologous bone graft material
This invention relates to a musculoskeletogenic MSG graft composite made from whole bone marrow aspirate BMA having native levels of musculoskeletal progenitor cells MSPCs, comprising: a) a...
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8137662 |
Proliferated cell lines and uses thereof
The subject invention pertains to tumor cell lines useful for increasing the proliferation potential of any human or animal cell in culture, thereby providing immortalized or continuous cell lines...
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8137972 |
Biocompatible, biodegradable polymer-based, lighter than or light as water scaffolds for tissue engineering and methods for preparation and use thereof
Scaffolds for tissue engineering prepared from biocompatible, biodegradable polymer-based, lighter than or light as water microcarriers and designed for cell culturing in vitro in a rotating...
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RE43258 |
Glue for cartilage repair
The invention is directed toward a sterile cartilage defect implant material comprising milled lyophilized allograft cartilage pieces ranging from 0.01 mm to 1.0 mm in size in a bioabsorbable...
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8128924 |
Methods for using a three-dimensional stromal tissue to promote angiogenesis
The present invention relates to a method for promoting blood vessel formation in tissues and organs. In particular, the method relates to implantation or attachment of an engineered...
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8128923 |
Renal carcinoma cell line and uses thereof
The present invention relates to a renal carcinoma cell line capable of activating the immune system in an antigen-specific manner. According to a further aspect, the invention also includes...
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8129183 |
Method for stimulating dendritic cells and cell product thus obtained for the autologous immunotherapy of solid human tumours
In the ex vivo stimulation method of dendritic cells, the stimulation occurs with the lysate of tumor spheres (TS) of the solid tumors.
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8124067 |
Method for immunotherapy of tumors
A method for making dendritic cells reactive to an antigen comprises obtaining a sample of dendritic cells and contacting the cells with the antigen and at least one Toll-like receptor stimulant....
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8124071 |
Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells
The invention provides novel methods of reducing transplant rejection and cardiac allograft vasculopathy in humans by employing the implantation of autologous progenitor cells into the transplanted...
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8119123 |
Compositions comprising vascular and myocyte progenitor cells and methods of their use
The invention provides compositions of adult cardiac vascular progenitor cells (VPCs) and adult cardiac myocyte progenitor cells (MPCs) useful for the treatment of various cardiac conditions. The...
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8119122 |
Use of gingival fibroblasts for vascular cell therapy
The invention relates to the use of gingival fibroblasts for obtaining a cellular composition for treating arterial-remodelling pathology, for example an aneurysm, post-cryoplasty stenosis and...
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8119121 |
Autologous adipose tissue implant with concentrated stem cells
Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained...
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8114670 |
Skin equivalent culture
Methods of forming soft connective tissue compositions such as skin equivalents, compositions made by the methods and their uses. In particular, a method of forming a connective tissue equivalent,...
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8114443 |
Phytase-expressing transgenic plants
Disclosed are a transgenic plant and a transformed plant cell containing a heterologous nucleic acid that includes a sweet potato sporamin SPO promoter operably linked to a sequence encoding a...
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8110399 |
Stem cells of the islets of langerhans and their use in treating diabetes mellitus
Methods and compositions are described for the treatment of type I insulin-dependent diabetes mellitus and other conditions using newly identified stem cells that are capable of differentiation...
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8110184 |
Ex vivo and in vivo methods and related compositions for generating hematopoietic stem cell populations
Various embodiments provide methods and related compositions for increasing the population size of hematopoietic stem cells (HSCs) in patients that may benefit from reconstitution of stem cells...
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8110213 |
Method of forming a tissue structure by introducing cells into an implanted matrix
Polymeric materials are used to make a pliable, non-toxic, injectable porous template for vascular ingrowth. The pore size, usually between approximately 100 and 300 microns, allows vascular and...
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8110185 |
Method for preventing and treating cardiovascular diseases with BRCA1
Methods for inhibiting cardiomyocyte apoptosis and/or to improving cardiac function and inhibiting inflammation-induced apoptosis in endothelial cells by delivering BRCA1 are provided. Such methods...
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8105580 |
Methods of using adipose derived stem cells to promote wound healing
Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells...
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8105491 |
Metabolic detoxification and method
An extracorporeal filtration and detoxification system and method generally comprise separating ultrafiltrate from cellular components of blood, treating the ultrafiltrate independently of the...
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8105581 |
Compositions and methods for inducing neuronal differentiation
The present invention provides compositions and methods for inducing neuronal cell differentiation.
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8105582 |
Tumour vaccine comprising allogenic or xenogeneic tumour cells
The present invention provides a composition for the treatment of a tumor, comprising: (i) allogeneic or xenogeneic tumor cells; and (ii) a pharmaceutically acceptable excipient. If two or more...
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8105634 |
Umbilical cord biomaterial for medical use
The present invention provides a biomaterial comprising a mammalian umbilical cord membrane. The biomaterial can additionally comprise Wharton's jelly and/or one or more umbilical cord vessels. The...
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8097244 |
Human prostate cell lines in cancer treatment
Combinations of cell lines are provided for allogeneic immunotherapy agents in the treatment of cancer. Cancer vaccines generally have been limited to the use of cells that contain at least some...
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8097274 |
Skin substitutes, preparation methods and uses thereof
Provided herein are skin substitutes suitable for use in a living subject for purpose of repairing damaged tissues, methods of producing the skin substitutes and their uses. A biocomposite membrane...
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8097248 |
Mite composition, use thereof, method for rearing the phytoseiid predatory mite Amblyseius sirskii, rearing system for rearing said phytoseiid mite and methods for biological pest control on a crop
The present invention relates to a novel mite composition comprising a population of the phytoseiid predatory mite species Amblyseius swirskii. and a factitious host population, which may be...
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