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8097245 |
Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same
The disclosure relates to a solid glass matrix of polysaccharide, saccharides and polyols as delivery vehicle for preservation and post gastric administration of a probiotic. The delivery vehicle...
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7935512 |
Colicinogenic strain of E. coli
Described herein is the isolation of colicin-producing strains of E. coli for use as probiotic treatments for the prevention of E. coli K88+ diarrhea. These strains of E. coli, designated as UM-17,...
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7927584 |
Lactic bacteria useful as probiotics
An isolated strain of Enterococcus faecalis GALT deposited under number CECT 7121 of the group of lactic bacteria is disclosed, which is capable of surviving and colonizing the gastrointestinal...
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7919081 |
Hydrogenase deficient bacterial strains
The present disclosure describes pathogenic bacteria that have been modified to be deficient in NiFe hydrogenase activity; compositions comprising such modified bacteria, and the use of such...
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7871604 |
Recombinant bacterial vaccine system with environmentally limited viability
Disclosed is an Environmentally Limited Viability System (ELVS) for microorganisms based on temperature differences between permissive and non-permissive environments. Viability of the...
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7790183 |
Combination of antimicrobial agents and bacterial interference to coat medical devices
This invention relates to a method for coating a medical device comprising the steps of applying to at least a portion of the surface of said medical device, an antimicrobial coating layer and a...
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7655241 |
Methods and compositions for vaccination against or involving enterobacteriaceae bacteria
The present invention concerns the use of methods and compositions to prophylactically or therapeutically vaccinate a subject against a pathogen or disease. Embodiments of the invention include the...
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7648832 |
Methods for lyophilizing competent cells
This invention relates to a method for producing cells which are competent for transformation and which may be stably stored for extended periods of time at various temperatures. The method...
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7541043 |
Vaccine for protection against Shigella sonnei disease
Compositions and methods for protecting a susceptable host against an infection of Shigella sonnei are disclosed. Such compositions and methods are useful for protecting the host against bacillary...
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7524507 |
Recombinant microorganisms
A method of enhancing expression of a desired protein at mucosal effector sites, the method including placing the protein to be expressed under the control of a promoter having SEQ ID NO: 2, SEQ ID...
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7238345 |
Recombinant microorganism expressing meningococcal class 1 outer membrane protein
Outer-membrane vesicles, Class 1 outer membrane proteins of Neisseria meningitidis, fragments or oligopeptides containing epitopes of the Class I OMP can be used to immunize against meningococcal...
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7195757 |
Modulation of immune responses to foreign antigens expressed by recombinant attenuated bacterial vectors
The present invention relates to immunogenic compositions comprising a live attenuated derivative of a pathogenic Enterobacteriaceae bacteria. The attenuated derivative of a pathogenic...
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7115269 |
Attenuated Salmonella strain used as a vehicle for oral immunization
The present invention is directed to an attenuated Salmonella comprising a eukaryotic expression vector for delivery of the eukaryotic expression vector to a eukaryotic cell. Delivery may be to...
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7018629 |
Probiotic compositions for the treatment of inflammatory bowel disease
Pharmaceutical compositions of probiotic E. coli strains and uses thereof for treating inflammatory bowel disease.
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6926889 |
Recombinant bacteria for use in insect control
The present invention relates to recombinant bacteria genetically engineered from insect hosts to express toxic gene products in a pest insect. The present invention also relates to a method of...
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6866847 |
Method of delivering a protein to poultry
A method of delivering a protein to domestic poultry by administering to the poultry by whole body spray an effective amount of a live avirulent derivative of an enteropathogenic bacterium that...
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6841149 |
Probiotic mixture intended for monogastric animals to control intestinal flora populations
A mixture of probiotics effective to reduce the contamination of enteric bacteria in humans and other monogastric animals. The mixture of probiotics includes one or more acid-producing bacteria...
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6790661 |
System for detecting bacteria in blood, blood products, and fluids of tissues
The invention provides methods for screening for the presence of a clinically relevant amount of bacteria in donor blood or a blood product from a donor mammal, particularly blood or a blood...
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6722062 |
Capsular polysaccharides from enterococci
The present invention is directed to a method for purifying polysaccharides capable of inducing the production of high titers of opsonic antibodies that kill strains of enterococcal bacteria. In...
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6713073 |
Method of vaccination of newly hatched poultry
A method of vaccinating poultry by spraying the poultry with an effective amount of a live avirulent derivative of an enteropathogenic enterobacteria is disclosed.
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6645530 |
Treatment of gastro-intestinal disorders
A method of treating chronic disorders associated with the presence of abnormal microflora or an abnormal distribution of microflora in the gastrointestinal tract involves removing the host's...
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6610529 |
Recombinant bacterial system with environmentally limited viability
Disclosed is an Environmentally Limited Viability System (ELVS) for microorganisms based on differences between permissive and non-permissive environments. Viability of the microorganisms are...
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6602506 |
Delivery of proteins into eukaryotic cells with recombinant Yersinia
The present invention relates to recombinant Yersinia and the use thereof for delivery of proteins into eukaryotic cells, including related compositions and methods of treatment and related assays.
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6565846 |
Microbial strains of pseudomonas, bacillus and enterobacter/in agricultural chemical compositions
A method for screening a bacterium antagonistic to pathogenic bacteria that emerge during raising of seedlings of gramineous plants utilizing tropolone resistance and tropolone non-producing...
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6528061 |
Immunogenic polypeptides that mimic a surface polysaccharide antigen of a pathogenic microorganism, method for obtaining the same, and their use in vaccine compositions
A purified immunogenic polypeptide comprises an epitope unit recognized by a protective monoclonal antibody having a high affinity and a high specificity for a surface polysaccharide of a...
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6517832 |
Formulations and methods for treating chronic migraine
A prophylactic treatment for the human malady clinically described as migraine headache comprising daily administration in unit dosage form of a first formulation which comprises a major amount of...
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6479056 |
Live vaccine constituting minor risk for humans
A salmonella live vaccine produced from at least one attenuated immunologic live vaccine strain, characterized in that the vaccine strain has an envelope marker which results in an increased...
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6428783 |
Bank of autochthonous strains of microorganisms and methods of its use for recovery of intestinal microbiocenosis of the men
The invention concerns microbiology and medicine and may be used for the prophylaxis and treatment of the syndrome of an irritated large intestine in either a human or an animal. The insertion of...
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6413523 |
Pharmaceutical composition of escherichia coli heat-labile enterotoxin adjuvant and methods of use
Novel immunoregulatory utilities of Escherichi coli heat-labile enterotoxin (LT) are disclosed. This enterotoxin can be used in combination with an unrelated antigen to achieve a higher immune...
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6403084 |
Mixed cultures for improved fermentation and aerobic stability of silage
Methods and compositions for treatment of animal feed or silage by treatment with a mixed culture of heterofermentive lactic acid bacteria and homofermentive lactic acid bacteria of the proper...
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6346422 |
Method of selecting bacterial strains
This invention relates to a method of selecting nonpathogenic bacterial strains capable of binding to the receptor sites for tissue adhesion of pathogenic bacterial strains, comprising the steps...
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6254874 |
Attenuated auxotrophic microorganisms having a combination of non-attenuating mutations and method for making same
A live non-virulent vaccine composition and method for preparing the same comprising a virulent microorganismal strain which contains at least two mutations, wherein the first mutation results in...
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6231871 |
Live in ovo vaccine
The present invention relates generally to modified microorganisms suitable for use as live in ovo vaccines for avian species. The live in ovo vaccines of the present invention are useful for...
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6190669 |
Attenuated mutants of salmonella which constitutively express the Vi antigen
Attenuated Salmonella mutants which constitutively express the Vi antigen are disclosed, as well as vaccines against typhoid fever containing the same, live vector vaccines containing the same, and...
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6153202 |
In ovo methods for utilizing live Edwardsiella ictaluri against enteric septicemia in channel catfish
Methods for the safe and effective live in ovo vaccination of eyed eggs of catfish against enteric septicemia of catfish (ESC) were created through the use of rifampicin resistant native E....
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6110455 |
Method for encouraging poultry to distribute and ingest competitive exclusion products
A method is disclosed for increasing the rate at which young poultry will ingest beneficial probiotic compositions effective against bacteria such as salmonella. The method includes the steps of...
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6083500 |
Biological control of food pathogens in livestock
The invention includes novel strains of E. coli and methods for treating livestock with strains of the invention to inhibit growth of S. typhimurium as well as other pathogenic enterobacteria, such...
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6080400 |
Compositions for the prevention and treatment of verotoxin-induced disease
The present invention includes methods for generating neutralizing antitoxin directed against verotoxins. In preferred embodiments, the antitoxin directed against these toxins is produced in avian...
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6019984 |
Bacterial preparations, method for producing same, and their use as vaccines
Novel bacterial preparations containing one or more isolated and purified strain of a microorganism which produces one or more RTX toxins, and which strain has at least one RTX toxin which is...
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6019981 |
Modified live Edwardsiella ictaluri against enteric septicemia in channel catfish
Safe and effective live vaccines against enteric septicemia of catfish (ESC) were created through the induction of rifampicin resistance in native E. ictaluri isolates; these including...
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6010705 |
Attenuated, invasive vaccines against fish pathogens
Live-attenuated vaccines against Edwardsiella ictaluri or against Pasteurella piscicida are disclosed. Both vaccines are incapable of reversion to virulence, because both are made by deletion...
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6007808 |
Pharmaceutical and diet formulations for the prophylaxis and treatment of gastrointestinal disorders
The present invention refers to pharmaceutical and diet formulations for the prophylaxis and treatment of gastrointestinal disorders.
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5965128 |
Control of enterohemorrhagic E. coli 0157:H7 in cattle by probiotic bacteria and specific strains of E. coli
The prevention and treatment of carriage of E. coli O157:H7 by a ruminant animal is accomplished by administering dominant probiotic bacteria to the animal. The dominant probiotic bacteria prevent...
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5951977 |
Competitive exclusion culture for swine
A defined probiotic or composition of anaerobic bacteria effective for controlling or inhibiting Salmonella colonization of swine is disclosed. The probiotic includes populations or cultures of...
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5855880 |
Avirulent microbes and uses therefor
This invention provides immunogenic compositions for the immunization of a vertebrate or invertebrate comprising an avirulent derivative of S. typhi. The derivatives having a mutation of the cya...
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5840318 |
Methods and compositions for modulating immune systems of animals
Methods and compositions for modulating the immune system of animals by activating macrophages to release cytokines and down-regulating their sensitivity to bacterial endotoxin and to conversion to...
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5767090 |
Microbially produced rhamnolipids (biosurfactants) for the control of plant pathogenic zoosporic fungi
Disclosed is the use of biosurfactants as biological control products. In particular, rhamnolipid biosurfactants produced by Pseudomonas spp. were demonstrated to rapidly kill zoospores by...
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5747020 |
Bacterial treatment for silage
Silage is preserved by treatment with a small, but silage preserving effective amount of a seven strain inoculant, in which five of the strains are members of the Lactobacillus plantarum taxon and...
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5733544 |
Nematicidal bacillus strain and metabolite and methods of use thereof
The present invention relates to a newly discovered Bacillus sp. strain which exhibits pesticidal activity. The supernatant of cultures of this novel isolate are also effective pesticidal agents....
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5728380 |
Priobiotic containing enterococcus faecium strain NCIMB 40371
A strain of Enterococcus faecium, deposited as NCIMB 40371, has valuable probiotic properties and is particularly effective in alleviating symptoms of irritable bowel syndrome (IBS) in human...
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