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8183026 |
Methods of preparation of live attenuated bacterial vaccine by alteration of DNA adenine methylase (Dam) activity in those bacteria
Live attenuated bacteria vaccines are provided. Also provided are methods by which such vaccines can be obtained, including: a method by which a copy of the dam gene from a pathogenic bacteria is...
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8183218 |
Agent for inducing apoptosis comprising MSX1 or a gene encoding the same as an active ingredient
The present invention relates to a novel use of Msx1 protein or a nucleotide encoding the same for inducing apoptosis. The Msx1 of the present invention induces apoptosis through direct interaction...
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8183025 |
Solenopsis invicta virus
A Unique Solenopsis invicta viruse (SINV2) have been identified and its genome sequenced. Oligonucleotide primers have been developed using the isolated nucleic acid sequences of the SINV2. The...
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8178087 |
Process of production of bacteriophage compositions and methods in phage therapy field
A method for producing bacteriophage stock compositions including (a) incubating a culture medium including at least one bacterial strain, at least one bacteriophage strain that can infect the...
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8178085 |
Methods of proliferating stem cells
The invention relates to methods of proliferating stem cells. More particularly, the invention relates to the use of glycosaminoglycans or proteoglycans to promote the growth of stem cells in ex...
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8178086 |
Activation of HCV specific T cells
Methods for activating HCV-specific T cells are described. The methods utilize one or more administrations of HCV protein compositions, followed by one or more administrations of a viral vector...
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8178084 |
Pharmaceutical kits comprising mesenchymal stem cells
A method of treating a natural soft skeletal tissue injury in a patient the method comprising administering to the patient a composition of mesenchymal stem cells in liquid suspension enriched...
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8178504 |
Gene therapy expression of GHRH for increasing RBC count in subjects
The present invention pertains to compositions and methods useful for treating anemia and other effects that are commonly associated in cancer bearing animals. The invention is accomplished by...
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8173104 |
Controlled-release immunogenic formulations to modulate immune response
Single-dose controlled-release immunogenic formulations, such as vaccines, based on bioerodible polyanhydride copolymer or homopolymer microparticles for the control of immune response mechanisms...
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8173613 |
Modulation of mesenchymal and metastatic cell growth
The present invention relates to compositions and methods for the modulation of metastatic and mesenchymal cell growth and mobility via the regulation of the formation of Twist/Twist homodimers and...
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8168215 |
Alginate coated, collagen matrix cellular device, preparative methods, and uses thereof
The present invention is directed to cellular devices comprising a collagen matrix, cell layer, and gelled alginate layer, processes for producing the devices, methods of implanting the devices,...
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8168167 |
Method for biologically combating the proliferation of Legionella pneumophila, and novel disinfecting agent containing amoebic protozoa of the Willaertia genus
The invention relates to a method for biologically combating the proliferation of Legionella pneumophila, with the exception of the treatment methods applied to the human or animal body,...
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8168166 |
Live genetically attenuated malaria vaccine
Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
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8163275 |
Multi-lineage progenitor cells
Fetal blood multi-lineage progenitor cells that are capable of a wide spectrum of transdifferentiation are described.
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8158119 |
Cardiac targeted delivery of cells
A method of delivering cardiac stem cell and treating damaged cardiac tissue is provided. The method involves isolation of subject's cardiac circulation from the subject's systemic circulation and...
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8158120 |
Cardiac muscle repair or regeneration using bone marrow-derived stem cells
Disclosed are compositions and methods for repairing and/or regenerating cardiac tissue by administering adult bone marrow-derived stem cells to an individual. These cells can be administered as a...
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8158416 |
CDNA corresponding to the antigenome of nonsegmented negative strand RNA viruses, and process for the production of such viruses encoding additional antigenically active proteins
The present invention relates, in general, to a methodology for the generation of nonsegmented negative-strand RNA viruses (Pringle, 1991) from cloned deoxyribonucleic acid (cDNA). Such rescued...
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8158596 |
Materials and methods for FOXP3 tumor suppression
Provided herein are methods of treating a cancer in a subject comprising administering a FOXP3 protein, a nucleic acid encoding a FOXP3 protein, or an inducing compound which induces FOXP3 protein...
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8158118 |
Mesenchymal precursor cell
A method of enriching mesenchymal precursor sells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for...
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8158121 |
Cardiac muscle regeneration using mesenchymal stem cells
Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered...
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8153119 |
Engineered enzymatically active bacteriophage and methods for dispersing biofilms
The present invention is directed to engineered enzymatically active bacteriophages that are both capable of killing the bacteria by lysis and dispersing the bacterial biofilm because they have...
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8153118 |
Method for altering the metabolism of plant
The invention is related to a method of altering the metabolism of a plant by carrying out the steps of treating seeds of the plant with non-genetically engineered selected mutant pink-pigmented...
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8153760 |
Rhinovirus vaccines
The present invention relates generally to peptide vaccines. More specifically, the present invention relates to vaccines against rhinoviruses and other related and non-related pathogenic animal...
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8148150 |
Method for the production of intervertebral disk cell transplants and their use as transplantation material
The invention relates to a method for the in vitro production of intervertebral disk cartilage cell transplants from affected intervertebral disk tissue from patients and to the use thereof as...
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8148136 |
Diagnostics and vaccines for mycobacterial infections of animals and humans
This invention relates to the protein, Mycobacterium paratuberculosis acylase (mpa) and the gene encoding mpa, which we have identified in the pathogen Mycobacterium paratuberculosis Mptb (also...
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8142774 |
Methods of treatment using electromagnetic field stimulated stem cells
Methods of modifying stem cells and compositions of modified stem cells, in particular mesenchymal stem cells, using electric or electromagnetic fields. In various embodiments, the present...
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8143042 |
Biodegradable elastomers
The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a...
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8142771 |
Use of coccidian
The present invention provides a novel use of coccidian, specifically relates to the use of coccidian as a vaccine live vector. The present invention further provides a live vaccine with coccidian...
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8142798 |
Augmentation of titer for vaccination in animals
The disclosure relates to a composition added to animal feed used in combination with a vaccine to enhance the effectiveness of the vaccine. Amongst other effects, the composition raises the titer...
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8142769 |
Preparation and xenotransplantation of porcine islets
The invention relates to developments in the treatment of diabetes in mammals. Particularly it relates to a method of preparing a xenotransplantable porcine islet preparation capable upon...
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8142773 |
Methods of implanting mesenchymal stem cells for tissue repair and formation
The invention relates to methods of isolating and implanting mesenchymal stem cells for tissue repair or formation, without prior culture expansion of the mesenchymal stem cells. In particular, the...
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8142760 |
Vaccination for Lawsonia intracellularis
The present invention include a method of protecting an animal against Lawsonia intracellularis infections, the method including administering a dose of live virulent L. intracellularis to the...
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8137663 |
Oncolytic virus therapy
A method of treating a human subject with cancer is disclosed. A pharmaceutical composition is administered to the subject, the pharmaceutical composition comprising human leukocytes and a...
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8137968 |
Selected endothelial progenitor cells and methods for use
The present invention is a method for preparing a substantially pure population of endothelial progenitor cells wherein said cells express Flk-1, CD34, α5β1 integrin fibronectin, and vWF and e...
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8137662 |
Proliferated cell lines and uses thereof
The subject invention pertains to tumor cell lines useful for increasing the proliferation potential of any human or animal cell in culture, thereby providing immortalized or continuous cell lines...
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8137718 |
Probiotic infant products
The present invention is directed to an infant formula or children's nutritional product comprising a protein source, a fat source, a carbohydrate source, and B. longum AH1205.
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8133481 |
Selectively replicating viral vectors
The present invention provides recombinant viruses which replicate the viral genome selectively in response to the intracellular conditions of the target cell through the use a pathway-responsive...
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8129172 |
Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
Disclosed is a process for growing the microflora Thraustochytrium, Schizochytrium, and mixtures thereof, which includes the growing of the microflora in fermentation medium containing non-chloride...
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8129352 |
Antisense antiviral compound and method for treating ssRNA viral infection
The invention provides antisense antiviral compounds and methods of their use and production in inhibition of growth of viruses of the Flaviviridae, Picornoviridae, Caliciviridae, Togaviridae,...
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8128921 |
Use of conditional plasmodium strains lacking nutrient transporters in malaria vaccination
The present invention relates to a malaria vaccine for administration to a host comprising an attenuated malarial parasite with a gene which has been rendered non-functional, wherein the gene, when...
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8129185 |
Regulatory T cells and their use in immunotherapy and suppression of autoimmune responses
Based upon a strong correlation between regulator T cells (Treg cells) and suppressing or preventing a cytotoxic T cell response, provided are methods for the production of ex vivo activated and...
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8124053 |
Compositions comprising chitin microparticles and their medical uses
The present invention relates to compositions comprising chitin microparticles and their medical uses, and in particular to compositions for use as vaccines which comprise antigen from an...
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8124067 |
Method for immunotherapy of tumors
A method for making dendritic cells reactive to an antigen comprises obtaining a sample of dendritic cells and contacting the cells with the antigen and at least one Toll-like receptor stimulant....
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8124592 |
Development of a preventive vaccine for filovirus infection in primates
The present invention relates generally to viral vaccines and, more specifically, to filovirus vaccines and methods of eliciting an immune response against a filovirus or disease caused by...
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8124068 |
Recombinant intracellular pathogen immunogenic compositions and methods of use
Immunogenic compositions comprising recombinant attenuated intracellular pathogens that have been transformed to express recombinant immunogenic antigens of the same or other intracellular...
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8124071 |
Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells
The invention provides novel methods of reducing transplant rejection and cardiac allograft vasculopathy in humans by employing the implantation of autologous progenitor cells into the transplanted...
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8119123 |
Compositions comprising vascular and myocyte progenitor cells and methods of their use
The invention provides compositions of adult cardiac vascular progenitor cells (VPCs) and adult cardiac myocyte progenitor cells (MPCs) useful for the treatment of various cardiac conditions. The...
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8119396 |
Recombinant adenoviral vectors and applications thereof
Recombinant adenoviruses or pseudoviruses having a deletion of all or part of the region of the adenovirus genome corresponding to nucleotides 311 to 499 in canine adenovirus type 2 (GeneBank...
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8119398 |
Adipose-derived stem cells for tissue regeneration and wound healing
Compositions and methods for promoting tissue regeneration, particularly skin regeneration, with adipose-derived stem cells are provided. Additionally methods and compositions for promoting tissue...
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8114669 |
Cell culture
A method for determining the effect of a plurality of culture conditions on a cell, comprising the steps of: a) providing a first set of groups of cell units each comprising one or more cells, and...
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