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9034300 Composition and method for medical imaging of body cavities  
A foamed aqueous image enhancing composition containing cellulose and/or cellulose derivative(s), has a pH between 5.5 and 7, wherein the viscosity of the composition is less than 1800 mPa·sec,...
9023321 Methods for producing microbubbles  
The present invention provides methods for the preparation of gas-filled microbubbles, and methods of using for therapeutic and/or diagnostic applications. In particular, the methods of the...
9011819 Optical imaging contrast agents and uses thereof  
The present invention generally relates to microbubble contrast agent compositions which are detectable by optical imaging methods, such as fluorescence, near-infrared or bioluminescence. Uses of...
8999295 Technique for drug and gene delivery to the cell cytosol  
Provided herein is a composition, a method, and a system for delivering a functional molecule to the cytosol of a cell, comprising a liposome configured to be taken into a cell, including by a...
8974770 Method for forming nano-bubble  
The present invention discloses a method for forming a nano-bubble. The forming method is different from the oil-water emulsion reaction in the prior art. The method comprises: taking an inorganic...
8940277 Intracellular microbubble for imaging an anatomical site  
This invention addresses the clinical problem of how to optimize biological cell based therapies, such as stem cell therapy. Currently, cell therapies administered by intravenous, intra-arterial,...
8747892 Preparation of a lipid blend and a phospholipid suspension containing the lipid blend  
The present invention describes processes for the preparation of a lipid blend and a uniform filterable phospholipid suspension containing the lipid blend, such suspension being useful as an...
8748497 Optimized fluorocarbon emulsions for blood substitutes and other therapeutic uses  
The present invention is directed to a stable fluorocarbon emulsion having a continuous aqueous phase and discontinuous fluorocarbon phase comprising two fluorocarbons and surprisingly...
8734762 Perfluorocarbon nano-emulsion containing quantum dot nanoparticles and method for preparing the same  
The present invention relates to a perfluorocarbon nanoemulsion containing quantum dot nanoparticles and a method for preparing the same, more specifically, relates to a method for preparing a...
8703110 Coating system  
Embodiments of the invention include a system comprising: an Acetoxy curable silicone Binder; and an active agent blended with the silicone binder, effective for one or more of radiopacification,...
8685441 Preparation of a lipid blend and a phospholipid suspension containing the lipid blend  
The present invention describes processes for the preparation of a lipid blend and a uniform filterable phospholipid suspension containing the lipid blend, such suspension being useful as an...
8679051 Microbubble medical devices  
Method and medical devices for generating and stabilizing micro- or nano-bubbles, and systems and methods for therapeutic applications using the bubbles, are provided. The micro-bubbles may be...
8642010 KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy  
The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever...
8622911 System for treatment and imaging using ultrasonic energy and microbubbles and related method thereof  
A method and related system for providing therapy to a treatment site, such as stenosis or other vasculature disease, at one or more locations of a subject, such as the vasculature. The method...
8551450 Targeting vector-phospholipid conjugates  
Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast...
8470298 Method of preparing a medium with bubbles formed therein for contemporaneous injection  
An apparatus, system or method enables microbubbles to be created on demand for use as the contrast agent within a contrast medium administrable to a patient for purposes of a medical procedure....
8454937 Method and composition for the site-selective delivery using viruses encapsulated in microbubbles  
Methods and compositions for the site-selective delivery of a gene to a site within the body of an animal where virus not encapsulated within the microbubbles is inactivated, for example by...
8441624 Dynamic characterization of particles with flow cytometry  
Flow cytometry concepts are modified to enable dynamic characterizations of particles to be obtained using optical scattering data. Particles in flow will be introduced into a sample volume. Light...
8323620 Ultrasound contrast agent  
An ultrasound contrast agent composed of at least one kind of low-boiling water-insoluble substance (with a boiling point lower than 37° C.) and at least one kind of high-boiling water-insoluble...
8264683 Dynamic characterization of particles with flow cytometry  
Flow cytometry concepts are modified to enable dynamic characterizations of particles to be obtained using optical scattering data. Particles in flow will be introduced into a sample volume. Light...
8257338 Medical microbubble generation  
Medical apparatus and processes controllably generate medically useful micro or nano bubbles of medically desirable and controllably selectable size, size distribution, homogeneity and...
8206746 Microparticles of water-insoluble substances  
The invention provides a composition comprising microparticles of a water-insoluble or poorly soluble compound, at least one phospholipid, and at least one surfactant, produced by applying an...
8177719 Contrast agent imaging with agent specific ultrasound detection  
Highly specific measurements of flow in vessels, such as the coronary artery, can be obtained by processing cubic fundamental information. By showing flow in vessels with a high degree of...
RE43048 Ultrasonic diagnostic imaging with harmonic contrast agents  
Apparatus and methods are disclosed for the detection and imaging of ultrasonic harmonic contrast agents. The harmonic echo effect is detected through alternate polarity acquisition of harmonic...
8084056 Preparation of a lipid blend and a phospholipid suspension containing the lipid blend  
The present invention describes processes for the preparation of a lipid blend and a uniform filterable phospholipid suspension containing the lipid blend, such suspension being useful as an...
8078256 Integrated multi-rail imaging system  
The imaging system can comprise a plurality of elongated rails, a scanhead assembly, and a small animal mount assembly. The scanhead assembly is selectively mounted onto a first rail and is...
8011826 Phantom  
This invention provides an ultrasonic phantom that can respond to different ultrasonic intensities. Such ultrasonic phantom comprises a gel comprising a low-boiling compound in the form of...
8012457 Ultrasound contrast agent dosage formulation  
Clinical studies have been conducted and specific dosage formulations developed using polymeric microparticles having incorporated therein perfluorocarbon gases that provide significantly enhanced...
7985402 Targeting vector-phospholipid conjugates  
Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast...
7910088 Multivalent constructs for therapeutic and diagnostic applications  
The invention provides compositions and methods for therapeutic and diagnostic applications.
7897141 Echogenic polymer microcapsules and nanocapsules and methods for production and use thereof  
Methods for producing echogenic polymer microcapsules and nanocapsules for use in diagnostic imaging and delivery of bioactive compounds as well as targeted imaging and delivery to selected...
7892522 Contrast agents  
Ultrasound contrast agents comprising microbubbles of biocompatible gas, e.g. a sulphur halide or a perfluorocarbon, stabilized by opsonisable amphiphilic material, e.g. a membrane-forming lipid...
7894880 Measurement of renal extraction fraction using contrast enhanced computed tomography  
Renal extraction fraction (EF) is determined through use of computed tomography (CT) measurements of arterial blood before and after injection of a radiographic contrast agent into the blood and...
7833359 Method for cleaning, employing a surfactant for fine-bubble formation  
A method for cleaning articles using a surfactant which is effective in the formation of stable microbubbles is provided. The surfactant for microbubble formation contains a (poly)oxyalkylene...
7804595 Using optical scattering to measure properties of ultrasound contrast agent shells  
A system and method for determining bubble shell properties using optical scattering. One or more ultrasound contrast agent (UCA) bubbles is placed in an imaging volume and illuminated with a...
7794693 Targeting vector-phospholipid conjugates  
Peptide vectors having high KDR binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast...
7753850 Method for ultrasound perfusion imaging  
An ultrasound imaging system transmits a broad beam of ultrasound into tissues that are perfused with blood containing microbubbles. The ultrasound has an intensity that is sufficient to destroy...
7620442 Colonography on an unprepared colon  
A method for generating colonography images for colorectal screening of a patient. The patient is administered an amount of radiopaque stool marker which will enable stool present in the patient's...
7597877 Administering a gravity segregation dispersion by continuous infusion  
Method and apparatus for continuous infusion to a subject of dispersions in which the dispersed phase is susceptible to flotation or sedimentation. The dispersion is controllably delivered from an...
7588547 Methods and system for treating subcutaneous tissues  
An apparatus and method for treating subcutaneous tissues using acoustic waves in the range of low acoustic pressure ultrasound waves is disclosed. The method includes injections of enhancing...
7560110 Production and use of novel peptide-based agents with bispecific antibodies  
The present invention relates to a bi-specific antibody or antibody fragment having at least one arm that specifically binds a targeted tissue and at least one other arm that specifically binds a...
7452551 Targeted compositions for diagnostic and therapeutic use  
Novel targeted compositions which may be used for diagnostic and therapeutic use. The compositions may comprise lipid, protein or polymer gas-filled vesicles which further comprise novel compounds...
7429249 Method for cavitation-induced tissue healing with low intensity ultrasound  
A method and kit for therapeutically treating bone and tissue injuries using ultrasound. The method includes the steps of introducing an ultrasound contrast agent into the patient, preferably, the...
7422733 Linkable sialyl Lewis X analogs  
Disclosed herein is a class of linkable tetrasaccharide compounds that includes the amino phenyl glycoside of sialyl Lewis X (SLeX) and related analogs. These compounds have conjugatable...
7374744 Harmonic ultrasound imaging with microbubbles  
A method for ultrasonic harmonic imaging is disclosed, which uses microbubbles particularly selected for their properties of reradiating ultrasound energy at frequencies other than the exciting...
7374745 Ultrasound contrast agents  
New ultrasound contrast agents that comprise microbubbles encapsulating a gas within a shell made from a blend of bipolar compounds having mixed carbon chain length. The compounds have hydrophobic...
7358226 Ultrasonic concentration of drug delivery capsules  
Methods, compositions and apparatus for localized delivery of compounds are provided. In certain embodiments, radiation force is used to direct carriers to a target site, and additional radiation...
7344705 Composition comprising low density microspheres  
Low density microspheres, methods for preparing same, and use of same as contrast agents are described. The microspheres have a void which contains a gas or the vapor of a volatile liquid selected...
7329402 Methods of imaging and treatment  
Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination...
7179449 Enhanced ultrasound detection with temperature-dependent contrast agents  
Methods and devices for enhanced ultrasound detection based upon changing temperature and ultrasound reflectivity of a temperature-dependent contrast agent bound to an ultrasound target are...

Matches 1 - 50 out of 255 1 2 3 4 5 6 >