Patents in Class 424/9.45

Matches 1 - 50 out of 190

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Match	Document	Document Title
1	8147805	Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications Compositions and methods for dual imaging and for dual chemotherapy and radiotherapy are disclosed. More particularly, the invention concerns compounds comprising the structure X1—Y—X2, wherein Y c...
2	8084018	Methods for imaging dopamine transporter level Presented is a method for assessing dopamine transporter levels in a selected area of a subject's central nervous system by SPECT imaging comprising administering an injection of a labeled dopamine...
3	7862800	Radiopaque cyanoacrylate compositions This invention relates to sterilized cyanoacrylate adhesive compositions with x-ray imagining capabilities, methods of making such compositions, and methods of using such compositions.
4	7863047	Intracorporeal medicaments for photodynamic treatment of disease New intracorporeal photodynamic medicaments and certain medical uses and methods for use of such photodynamic medicaments for treatment of disease in human or animal tissue are described, wherein a...
5	7713517	Compositions and methods for enhancing contrast in imaging Example compositions of liposomes with hydrophilic polymers on their surface, and containing relatively high concentrations of contrast-enhancing agents for computed tomography are provided....
6	7666390	DTPA derivatives and metal complexes thereof, and radiation source and contrast agent including the metal complexes The present invention relates to diethylenetriamine pentaacetic acid (DTPA) derivates and metal complexes thereof, and radiation sources and contrast agents including the metal complexes. More...
7	7588751	Liposome-containing radiographic contrast medium and preparation method thereof A method of pereparing a rediographic contrast medium containing liposomes is disclosed, comprising (a) dissolving a phospholipid and a sterol in a supercritical or subcritical carbon dioxide in...
8	7507394	High viscosity embolizing compositions Disclosed are novel compositions for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery.
9	7427389	Diagnostic agents for positron emission imaging using radiolabeled halogenated xanthenes New diagnostic agents for positron emission tomography (PET) and methods for use of such agents for imaging of human or animal tissue are described, wherein a primary active component of such...
10	7402299	Intracorporeal medicaments for photodynamic treatment of disease New intracorporeal photodynamic medicaments and certain medical uses and methods for use of such photodynamic medicaments for treatment of disease in human or animal tissue are described, wherein a...
11	7384623	High energy phototherapeutic agents High energy phototherapeutic agents or radiosensitizer agents comprised of a halogenated xanthene, or other related agents that exhibit a preference for concentration in biologically sensitive...
12	7378081	Composition and method for direct visualization of the human appendix A positive contrast agent composition containing meglumine diatrizoate, sodium diatrizoate, simethicone, famotidine and aspartame in predetermined amounts that is orally administered to a patient...
13	7368101	Process for the preparation of iopamidol and the new intermediates therein A process for the preparation of (S)-N,N′-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydro xy-1-oxo-propyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide (iopamidol) starting from 5...
14	7338652	Methods for positron emission imaging with radiolabeled halogenated xanthenes diagnostic agents New diagnostic agents for positron emission tomography (PET) and methods for use of such agents for imaging of human or animal tissue are described, wherein a primary active component of such...
15	7189383	Radioactively labelled amino acid analogues, their preparation and use The present invention relates to Halogenated amino acid analogues for use in diagnosis, which compounds have the general formula (I) wherein: R is (C1–C6) alkyl optionally substituted with t...
16	7175828	Modulators of β-amyloid peptide aggregation comprising D-amino acids Compounds that modulate natural β amyloid peptide aggregation are provided. The modulators of the invention comprise a peptide, preferably based on a β amyloid peptide, that is comprised entirely o...
17	7151117	Concentrated X-ray contrast media can act as universal antigens and can inhibit or prevent allergic reactions The present application is directed to the use of X-ray contrast media that act as universal antigens that are labeled herein as “pseudoantigens.” X-ray contrast media have the potential to exi...
18	7008614	Liposome containing hydrophobic iodine compound and X-ray contrast medium for radiograph comprising the liposome A liposome containing a hydrophobic iodine compound represented by the following general formula (I) as a membrane component: R1—CO2—R2 wherein R1 represents a substituted or unsubstituted 2,3...
19	6660248	Fullerene (C60)-based X-ray contrast agent for diagnostic imaging An contrast agent for therapeutic or diagnostic treatment comprises a fullerene scaffold and an iodinated moiety bonded to the scaffold. The agent may further comprise a water solubilizing moiety...
20	6599448	Radio-opaque polymeric compositions The present invention provides a radio-opaque composition including a polymer or monomer, wherein the polymer or monomer has a non-leachable radio-opaque moiety. The non-leachable radio-opaque...
21	6531111	High viscosity embolizing compositions Disclosed are novel compositions for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery.
22	6509406	Plastic molding materials which can be detected by X-ray contrast The invention provides X-ray contrastable plastics materials with low-molecular weight iodine compounds, a process for preparing X-ray contrastable plastics materials with low molecular weight...
23	6479033	Antitumor cystostatic and contrast agent The invention concerns a composition for the treatment of tumors, of (i) at least one cytostatic drug component which is unencapsulated or is encapsulated in a PEG-, immuno-, or immuno/PEG...
24	6475466	Methods for treating endoleaks during endovascular repair of abdominal aortic aneurysms Disclosed are methods for treating endoleaks arising from endovascular repair of abdominal aortic aneurysms. The disclosed methods involve the in situ sealing of endoleaks after placement of an...
25	6426145	Radiopaque compositions for visualization of medical devices A radiopaque polymeric composition useful as a polymer coating on a substrate. The compositions are designed to be bioabsorbable and are particularly useful on implantable medical devices, such as...
26	6264916	N,N-dimethyldiatrizoic acid and its conjugates as hepatobiliary agents for x-ray CT imaging Compounds having formulae I, II or/III, or pharmaceutically acceptable salts thereof, ##STR1## R1, R2, R3, R4, R5, R6, R7 and R8 are the same or different and are hydrogen, alkyl, substituted or...
27	6217849	Liposome suspensions as blood pool imaging contrast agents The present invention concerns injectable blood pool contrast agents for NMR and X-ray imaging purpose. These blood pool agents carry imaging contrast enhancers, e.g. paramagnetic or, respectively,...
28	6207133	Anti-tumoral therapy agent containing a contrast agent The invention relates to a new anti-tumoral therapy agent based on liposome-encapsulated cytostatic agents and/or the metabolites thereof. The invention can be used in the pharmaceutical industry...
29	6072069	Biodegradable nonionic contrast media Novel non-ionic contrast media are provided, which fulfill the requirements for x-ray visualization media, while being biodegradable. The compounds are characterized by being...
30	6001333	Methods of preparing micro encapsulated agents for use in the detection of tumors by CT imaging X-ray contrast media encapsulated within 50 nm to 10 μm microspheres were shown to be a superior contrast agent for CT imaging of liver tumors. Use of the encapsulated agent resulted in ...
31	RE36418	Contrast media comprising a non-ionic contrast agent with low levels of sodium and calcium ions The physiological acceptability of contrast media, especially media for use in angiography, may be enhanced by inclusion of sub-plasma levels of sodium and calcium and, optionally, potassium and/or...
32	5846515	Calixarene conjugate diagnostic agents for computerized tomography and method for using same Calixarene conjugates useful for imaging, particularly magnetic resonance imaging (MRI) and computed tomography (CT) are described. Said calixarene conjugates comprise (i) a calixarene backbone,...
33	5756066	Iodine-containing peptides Iodine-containing peptides of general formula I ##STR1## in which R1, R2, R3, R4, a, m and q have the meanings indicated in the description, agents containing these compounds, the use of compounds...
34	5746998	Targeted co-polymers for radiographic imaging A radiographic imaging agent including a plurality of block copolymers forming a micelle, the block copolymers including a hydrophilic polymer linked to a hydrophobic polymer, and the hydrophobic...
35	5725840	Steroidal ester contrast media for x-ray and magnetic resonance imaging The present invention relates to metabolically labile esters, and to contrast media for X-ray and magnetic resonance imaging comprising these esters. The esters have formula (I): ##STR1## in which...
36	5695742	Aqueous injectable formulations useful for radiodiagnosis comprising iodinated aromatic compounds used as X-ray contrast media This invention refers to injectable aqueous formulations containing radiopaque contrast agents useful for X-ray imaging of human or animal body. This invention specially deals with injectable...
37	5686061	Particulate contrast media derived from non-ionic water soluble contrast agents for CT enhancement of hepatic tumors The present invention provides a method for chemically modifying non-ionic, water soluble particulate contrast agents so that they degrade in vivo to their non-ionic parent contrast material and...
38	5670136	2,4,6-triiodo-5-substituted-amino-isophthalate esters useful as x-ray contrast agents for medical diagnostics imaging Compounds having the structure: ##STR1## wherein Q is ##STR2## n is an integer from 0 to 20; R1 is H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxyalkyl or acetamidoalkyl; R2, R3, R4 and R5...
39	5668196	3-amido-triiodophenyl esters as x-ray contrast agents This invention relates to methods of x-ray diagnostic imaging the blood pool, liver, spleen and/or lymph system of a mammal comprising administering a contrast effective amount of a contrast agent...
40	5665331	Co-microprecipitation of nanoparticulate pharmaceutical agents with crystal growth modifiers This invention describes the coprecipitation of nanoparticulate pharmaceutical agent dispersion via a process that comprises the dissolution of the said pharmaceutical agent in combination with a...
41	5643552	Nanoparticulate diagnostic mixed carbonic anhydrides as x-ray contrast agents for blood pool and lymphatic system imaging This invention relates to methods of x-ray diagnostic imaging the blood pool, liver, spleen, and/or lymph system of a mammal comprising administering a contrast effective amount of a mixed carbonic...
42	5628981	Formulations of oral gastrointestinal diagnostic x-ray contrast agents and oral gastrointestinal therapeutic agents Nanoparticulate crystalline x-ray contrast agents are formulated with stabilizers to enhance contact between the crystalline x-ray contrast agents and the gastrointestinal tract.Nanoparticulate...
43	5626832	Injectable opacifying composition containing liposomes of high encapsulation capacity for X-ray examinations Injectable aqueous composition intended for opacifying certain organs with a view to examination by X-rays. This composition is based on liposomes containing, encapsulated thereein, an aqueous...
44	5622938	Sugar base surfactant for nanocrystals Dispersible particles consisting essentially of a crystalline drug substance having a surface modifier having the formula: ##STR1## wherein R is phenyl-(CH2)10 CO or C12 H25 NHCO adsorbed on the...
45	5620677	Compositions of iodophenoxy alkanes and iodophenyl ethers for visualization of the gastrointestinal tract Disclosed are contrast agents of the formula ##STR1## contained in aqueous compositions and methods for their use in diagnostic radiology of the gastrointestinal tract wherein Z=H, halo, C1 -C20...
46	5607660	Compositions of iodophenoxy alkanes and iodophenyl ethers in combination with cellulose derivatives for visualization of the gastrointestinal tract Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising an iodophenoxy alkane, iodophenyl alkenylalkyl ether or an iodophenyl...
47	5603916	3 5-bis alkanoyl amino-2 4 6-triiodobenzyl esters This invention relates to methods of x-ray diagnostic imaging the blood pool, liver, spleen and/or lymph system of a mammal comprising administering a contrast effective amount of a contrast agent...
48	5587143	Butylene oxide-ethylene oxide block copolymer surfactants as stabilizer coatings for nanoparticle compositions This invention provides a composition comprised of nanoparticles containing a therapeutic or diagnostic agent having a nonionic polymeric surfactant as a surface modifier adsorbed on the surface...
49	5575905	Iodination process The invention provides a process for the preparation of a 2,4,6-triiodinated or 2,4,6,2',4',6'-hexaiodinated 3,5-disubstituted-aniline or 3,3'-disubstituted-5,5'-linked bisaniline, which process...
50	5573749	Nanoparticulate diagnostic mixed carboxylic anhydrides as X-ray contrast agents for blood pool and lymphatic system imaging This invention relates to methods of x-ray diagnostic imaging the blood pool, liver, spleen, and/or lymph system of a mammal comprising administering a contrast effective amount of a mixed carbonic...

Matches 1 - 50 out of 190

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