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7588754 |
Biodegradable polyacetals and methods
Condensation polymerization methods are used to prepare various biodegradable polyacetals of the general formula (I). Such polymers are useful for variety of drug, biomolecule and imaging agent...
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7563460 |
Enteric coated oral pharmaceutical to erode kidney stones
A treatment protocol by which a renal stone patient is administered a chelating agent, generally once a day and preferably by mouth, during a treatment phase and is later administered the same...
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7504095 |
Method for obtaining precursor Z and use thereof for the production of a means for therapy of human molybdenum cofactor deficiency
The invention relates to a method for obtaining the molybdopterin derivative precursor Z, wherein an over-production of precursor Z occurs in host organisms by recombinant expression of precursor Z...
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7052686 |
Pegylated interleukin-10
Interleukin-10 (IL-10) conjugated via a linker to one or more polyethylene glycol (PEG) molecules at a single amino acid residue of the IL-10, and a method for preparing the same, are provided. The...
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7041281 |
Natural feel polymers
Natural feel polymers exhibit an advantageous blend of flexibility and a strong affinity to natural fibers imparting a natural feel when applied to keratin-based fibers, e.g. hair, skin, or...
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7018625 |
Personal care compositions
Personal care compositions, particularly hair care products, include a polymer mixture made from (A) a derivatized polymer of maleic anhydride having defined repeat units of a monomer (e.g....
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7005125 |
Personal care products
Personal care products, particularly hair care products, are made herein by mixing (A) a polymer having defined repeat units of a monomer (e.g. α-olefin) maleic anhydride alkyl half-ester or full...
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6989362 |
Methods of treating dopamine dysregulation using agents that regulate phosphorylation/dephosphorylation in dopamine signaling
The present invention discloses that DARPP-32 is substrate for the cyclin dependent kinase Cdk5. The phosphorylation takes place at a specific threonine residue of DARPP-32 (Threonine 75). The Cdk5...
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6732573 |
Single riser/single capillary blood viscometer using mass detection or column height detection
An apparatus and method for determining the viscosity of the circulating blood of a living being over plural shear rates caused by a decreasing pressure differential by monitoring the changing...
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6630167 |
Hyaluronic acid anti-adhesion barrier
Methods of forming crosslinked hyaluronic acid anti-adhesion barriers, crosslinked hyaluronic acid anti-adhesions barriers, methods for preventing or inhibiting adhesions, and methods of promoting...
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RE37950 |
Biogradable in-situ forming implants and methods of producing the same
A biodegradable polymer is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to...
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6464970 |
Method and composition for preventing surgical adhesions
An improved method and composition for preventing adhesions during surgery. Tissue surfaces and surgical articles involved in the surgery are coated with a solution of a hydrophilic, polymeric...
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6419916 |
Assay for compounds which affect conformationally altered proteins
An assay comprises contacting cells containing a conformationally altered protein with test compound and determining if the altered protein is cleared. The cells may be scrapie-infected...
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6387391 |
Bioresorbable polymeric clayey and sticky substance
This invention provides a claycy and sticky substance as a new biomaterial that cannot be found in the current medical field, which is bioresorbable, shows tackiness, plasticity and shape holding...
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6277889 |
Molluscicide formulation
A molluscicide containing a non-toxic animal repellant and metaldehyde, in which the molluscicidal efficacy of the molluscicide greater than that of the molluscicide if it did not contain...
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6271264 |
Polymers containing spirobicyclic ammonium moieties as bile acid sequestrants
The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises administering a therapeutically effective...
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6214366 |
Clearance and inhibition of conformationally altered proteins
The present invention provides a method of arresting, preventing and/or reversing the impairment of central and peripheral nervous system function comprising reducing insoluble protein deposit...
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6190688 |
Material for elimination or detoxification of super antigens
A material with excellent selective absorption of super antigens. Said material contains urea bonds or thiourea bonds and remains active even in a high protein concentration solution in the neutral...
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6048523 |
Polyester cyclic compounds, their complexes and bonded bodies
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6037387 |
Blood-compatible material of a supramolecular structure
A platelet metabolism suppressing blood compatible material has a supramolecular structure containing a plurality of cyclic compounds and a hydrophilic straight-chain polymer threading into...
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5962566 |
Biocompatible and biodegradable nanoparticles designed for proteinaceous drugs absorption and delivery
The presently claimed invention comprises a biopolymer nanoparticle for drug delivery wherein the nanoparticle comprises a homogeneous blend of an aliphatic polyester polymer blended with a...
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5939537 |
Acid-functionalized saccharide monomers
The present invention includes polymerizable monomers comprising an acid-functionalized glycoside moiety. The monomer can have a polymerizable functional group, such as an olefinic bond, to which...
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5922682 |
Polyol esters, their preparation and use in depot forms of pharmacologically active agents
This invention provides a polyester of a polyol, said polyol containing at least 3 hydroxyl groups and having a molecular weight of up to 20,000 at least 1 hydroxyl group in said polyol being in...
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5919830 |
Stable non-aqueous blends for personal care compositions
A stable non-aqueous carrier for personal care compositions comprising: a) about 80-98% by weight of a liquid polyoxyalkylene glycol of MW=3000-100000; b) about 2-20% by weight of a non-ionic...
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5902589 |
Method for treating hydratable polymers, compositions obtained therefrom, and methods of using same
Aqueous solutions of hydratable polymers are prepared by hydrating a hydratable polymer in water without agitation sufficient to shear the molecular structure of the polymer thereby maintaining...
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5888518 |
Method for preventing and treating coccidiosis
A method for preventing and treating parasitic infections in animals by administering a lysine analog, such as EACA, to the animals on a continuous basis. In the preferred embodiment, the method of...
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5858348 |
Perfume composition containing (4R)-cis-4-methyl-2-substituted-tetrahydro-2H-pyran derivative and method for improving fragrance by using (4R)-cis-4-methyl-2-substituted-tetrahydro-2H-pyran derivative
A perfume composition which contains a (4R)-cis-4-methyl-2-substituted-tetrahydro-2H-pyran derivative represented by formula (I): ##STR1## wherein ---- represents a single or double bond, and a...
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5853713 |
Biologically compatible linear block copolymers of polyalkylene oxide and peptide units
A linear block copolymer comprising units of an alkylene oxide, linked to units of peptide via a linking group comprising a --CH 2 CHOHCH 2 N(R)-- moiety, is useful as an imaging agent, drug,...
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5844061 |
Polyphenol derivative compositions and perparation thereof
Polyphenol derivative compositions including oligomer or polymer esters containing N+2 monomer moieties, whose monomer moieties correspond to the following formula ##STR1## in which N is a number...
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5788958 |
Methods for improving therapeutic effectiveness of agents for the treatment of solid tumors and other disorders
The present invention is directed to the use of an inhibitor of NO activity, such as a nitric oxide scavenger or an NO synthase inhibitor, as an antitumor therapy to reduce tumor blood flow and...
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5719194 |
Prevention and treatment of topical viral infections with perfluoropolyethers or compositions thereof
Use of perfluoropolyethers with non reactive terminals or compositions thereof for the prevention and/or the treatment of topical vital infections, in particular of Herpes Simplex I and II and of...
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5718909 |
Sheet containing carbohydrate derivative for removal of E. coli
A sheet of nonwoven material which can be used as cleansing product in the form of a wet tissue for effective removal of bacteria, especially type 1 piliated E. coli, when wiping for example the...
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5711936 |
Ultramulsion based ingestible compositions
The present invention relates to various ingestible products containing stable, dispersions of certain high viscosity silicones in certain surfactants for use in treating mucus containing surfaces...
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5702695 |
Osseointegration promoting implant composition, implant assembly and method therefor
A liquid composition comprising a transforming growth factor β(TGF-/β in a polyoxyalkylene block copolymer--containing liquid carrier which gels at about 37 C, promotes osseointegration of an...
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5575993 |
Ionene polymers containing biologically-active anions
Ionene polymers having biologically-active organic and/or inorganic anions are described. Methods to prepare the ionene polymers, compositions containing them and their methods of use are also...
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5567422 |
Azlactone activated polyalkylene oxides conjugated to biologically active nucleophiles
Water-soluble azlactone activated polyalkylene oxides having improved hydrolytic stability and conjugates of the azlactone activated polyalkylene oxides with biologically active nucleophiles are...
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5525332 |
Cosmetic treatment of substrates
A cosmetic composition, especially for providing a conditioning benefit to hair, is provided incorporating an azlactone-functionalized copolymer consisting of vinyl azlactone and methacryloyl...
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5496546 |
Compositions and methods of application of reactive antiviral polyadenylic acid derivatives
Novel polyadenylic acid (5') derivatives with 2'-0-(3-fluoro-4,6-dinitrophenyl) groups and/or 2'-0-(2,4-dinitrophenyl) groups have been synthesized and discovered to act as mutation-insensitive and...
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5494661 |
Methods for using proanthocyanidin polymers having antiviral activity
The present invention provides for proanthocyanidin polymers with significant antiviral activity. The proanthocyanidin polymers can be chemically synthesized or can be isolated from a Croton or a...
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5482719 |
Drug delivery systems
A photoactivatable drug delivery system is provided, in which a drug is combined e.g. by covalent bonding, incorporation in a matrix or encapsulation, with a photosensitive macromolecule. In...
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5412068 |
Medical devices fabricated from homopolymers and copolymers having recurring carbonate units
This invention relates to medical devices formed totally or in part from homopolymers or copolymers comprising recurring carbonate moieties.
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5399343 |
Biocidal cosmetic compositions
A cosmetic or body composition containing an effective amount of a non-leachable anti-microbial polymer. The polymer contains carboxyl groups which are at least partially neutralized or exchanged...
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5334382 |
Lyophilized polyethylene oxide modified catalase composition, polypeptide complexes with cyclodextrin and treatment of diseases with the catalase compositions
Disclosed are lyophilized biologically active proteinaceous compositions containing low diol polyalkylene oxide, such as polyethylene glycol, covalently attached to a biologically active...
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5160734 |
Sustained release delivery system for substituted dihydropyridine calcium channel blockers
Complex of 1,4-dihydropyridine with polyoxyethylene-polyoxypropylene copolymer useful in sustained release dosage formulations.
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5152979 |
Method for treating vascular obstructions caused by abnormal cells
In accordance with the present invention, a method is provided for treating ischemia resulting from microvascular compromise caused by abnormal cells in the blood stream, which is often a...
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5142010 |
Polymeric biocidal agents
An antimicrobial polymerizable compound and polymers resulting therefrom, the compound being ##STR1## wherein A is any polymerizable group; Q is phenylene; and R is --(CF 2 ) y CF 3 wherein...
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5124144 |
Orally administered pharmaceutical composition for use in gastrointestinal washes, in particular for diagnostic use, or as a cathartic laxative
The invention provides an orally administered pharmaceutical composition for use in gastrointestinal washes, particularly for diagnostic use, or as a cathartic laxative, of the type containing...
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5114708 |
Method for stimulating growth in animals
The present invention relates to biologically-active copolymers and to compounds that can be safely used to cause the thymus of an animal or human to increase in size, thereby replenishing the...
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5108741 |
Anti-fungal treatment method using polyethylene oxide powder
There is provided a new and useful method for the treatment of fungal infections comprising applying to the infected area a composition containing from 0.5 to 100% of an ethylene oxide polymer.
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5108740 |
Antimicrobial film-forming compositions containing polymers having pendant pyran groups
The present invention provides a liquid composition that yields an abrasion resistant polymeric film on a surface that provides extended protection from microbial growth through slow release of a...
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