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7608678 |
Hydrolytically degradable polymers and hydrogels made therefrom
A water soluble polymer is described, the water soluble polymer comprising multiple hydrolytically degradable carbonate linkages in a backbone and, for each carbonate linkage in the backbone, an...
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7597882 |
Protein crosslinkers, crosslinking methods and applications thereof
Some aspects of this disclosure relate to a method for crosslinking a biological fluid comprising combining a biological fluid with a crosslinker to covalently crosslink proteins endogenous to the...
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7588754 |
Biodegradable polyacetals and methods
Condensation polymerization methods are used to prepare various biodegradable polyacetals of the general formula (I). Such polymers are useful for variety of drug, biomolecule and imaging agent...
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7547765 |
Branched polyalkylene glycols
The present invention provides a branched polyalkylene glycol wherein three or more single-chain polyalkylene glycols and a group having reactivity with an amino acid side chain, the N-terminal...
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7534907 |
Absorbable α-cyanoacrylate compositions
A monomer composition comprising at least one polymerizable alkyl ester α-cyanoacrylate monomer. Specifically, the α-cyanoacrylate monomer is an alkyl ester α-cyanoacrylate monomer of the...
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7534852 |
Polyanhydrides with therapeutically useful degradation products
An aromatic polyanhydride comprising a repeating unit having the structure
is disclosed, wherein Ar and R are selected so that the aromatic polyanhydride hydrolyzes to form a therapeutic...
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7442370 |
Polymer conjugates of mutated neublastin
A dimer comprising a mutated neublastin polypeptide coupled to a polymer is disclosed. Such dimers exhibit prolonged bioavailability and, in preferred embodiments, prolonged biological activity...
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