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8119114 |
Polymer conjugates of mutated neublastin
A dimer comprising a mutated neublastin polypeptide coupled to a polymer is disclosed. Such dimers exhibit prolonged bioavailability and, in preferred embodiments, prolonged biological activity...
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8062649 |
Hydroalcoholic compositions thickened using polymers
An antimicrobial hydroalcoholic composition comprising hydroalcoholic solvent system comprising a lower alcohol and water in a weight ratio of at least about 50:50; a thickener system comprising at...
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8017109 |
Endosomolytic poly(acrylate) polymers
The present invention is directed to membrane active polymers useful for cellular delivery of compounds. Described are polyconjugates systems that incorporate targeting, anti-opsonization,...
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7988956 |
Hydrolytically degradable carbamate derivatives of poly(ethylene glycol)
Poly(ethylene glycol) carbamate derivatives useful as water-soluble pro-drugs are disclosed. These degradable poly(ethylene glycol) carbamate derivatives also have potential applications in...
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7985406 |
Membrane active heteropolymers
The present invention is directed to a class of membrane active polymers useful for cellular delivery of compounds. Conjugation of the described membrane active polymers to targeting,...
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7976834 |
Multi-arm polypeptide-poly(ethylene glycol) block copolymers as drug delivery vehicles
The invention provides a multi-arm block copolymer for use in delivering a variety of bioactive agents. The copolymer of the invention contains a central core from which extend multiple (3 or more)...
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7910120 |
Adhesive block ethylenic copolymers, cosmetic compositions containing them and cosmetic use of these copolymers
A cosmetic composition where a linear, block ethylenic copolymer is dissolved in a physiologically acceptable medium, wherein the linear, block ethylenic copolymer improves the hold of hair...
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7906126 |
Adhesive block ethylenic copolymers, cosmetic compositions containing them and cosmetic use of these copolymers
A cosmetic composition of a linear, block ethylenic copolymer dissolved in a physiologically acceptable medium where the linear, block ethylenic copolymer includes at least two blocks having...
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7875265 |
Cosmetic composition comprising a sequenced polymer and a plasticizer
A subject matter of the invention is a cosmetic composition comprising a cosmetically acceptable organic liquid medium, a block polymer and a plasticizer, characterized in that: the block polymer...
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7854924 |
Methods and compositions for treatment of ion imbalances
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodium-binding polymers and pharmaceutical...
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7838122 |
Hydrazide compounds with angiogenic activity
Compounds exhibiting angiogenic properties incorporating the structure of Formula I: R3—NH—NH—C(═O)—R2—P—R1 (I) wherein P is a water-soluble, biodegradable polymer, R1 is hydrogen, lower alkyl, ...
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7767197 |
Delivery vehicle composition and methods for delivering antigens and other drugs
The present invention provides an immunogen composition and methods for using the same for the development of immunity, and particularly at mucosal sites in a mammal, thereby providing immunity at...
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7678369 |
Anionic polymers as toxin binders and antibacterial agents
The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of...
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7662365 |
Polymer conjugates of opioid antagonists
The invention provides polymer conjugates of opioid antagonists comprising a polymer, such as poly(ethylene glycol), covalently attached to an opioid antagonist. The linkage between the polymer and...
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7544348 |
Liquid formulations for the prevention and treatment of mucosal diseases and disorders
Stable, viscous, mucoadhesive aqueous compositions which are useful for the prevention and treatment of ulcerative, inflammatory, and/or erosive disorders of mucous membranes, especially mucositis.
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7465440 |
Process for preparing water-soluble or water-dispersible polyether-containing polymers and the use thereof as coating agents, binders and/or film-forming excipients in pharmaceutical dosage forms or packaging materials or as additives in cosmetic, dermatological or hygienic preparations
A process for preparing graft copolymers of polyvinyl esters by polymerization of a) at least one vinyl ester of aliphatic C1-C24-carboxylic acids in the presence ofb) polyethers which are solid at...
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7425322 |
Responsive biomedical composites
A responsive polymeric system including a responsive polymeric component capable of undergoing a transition that results in a sharp increase in viscosity in response to a triggering effected at a...
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7420029 |
Tissue-specific transporter inhibitor
The present invention is to provide a tissue-specific transporter inhibitor which is not absorbed through the digestive tract and can prevent deterioration in the QOL of a patient caused by diet...
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7332477 |
Photocleavable DNA transfer agent
The present invention provides visible light sensitive and ultraviolet (UV) light sensitive composition for DNA transfer comprising acid sensitive polyacetals developed as DNA/RNA delivery agents,...
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7323163 |
Film-forming compositions and methods
Film-forming compositions, as well as methods of making and using, wherein the compositions include an optional active agent, water, a surfactant, and a water-soluble or water-dispersible vinyl...
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7316816 |
Temperature and pH sensitive copolymers
The invention is directed to a copolymer comprising at least three types of monomeric units, said three types of monomeric units comprising: a temperature-sensitive unit,a hydrophilic unit, anda...
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7316811 |
Multi-arm polypeptide-poly (ethylene glycol) block copolymers as drug delivery vehicles
The invention provides a multi-arm block copolymer for use in delivering a variety of bioactive agents. The copolymer of the invention contains a central core from which extend multiple (3 or more)...
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7153498 |
Water-in-oil emulsion and its use as a cosmetic
A composition, comprising, in a physiologically acceptable medium, an aqueous phase dispersed in an oily phase by means of an emulsifier of at least one oligomer or one polymer derived from a...
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7144573 |
Latent reactive blood compatible agents
A reagent and related method for use in passivating a biomaterial surface, the reagent including a latent reactive group and a bifunctional aliphatic acid (e.g., fatty acid), in combination with a...
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7125547 |
Poly(diallylamine)-based bile acid sequestrants
The present invention relates to a method for removing bile acids from a patient and certain polymers of use in the method. The method comprises the step of administering to the patient a...
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7105153 |
Thickener-rheology modifier system for personal care compositions
A thickener-rheology modifier system for use in hair care and skin care compositions comprising: a) a hydrophobically modified, alkali-soluble copolymer thickener comprising an aqueous emulsion...
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7087700 |
Polymeric urethane ester tertiary amines and related personal care formulations
The present invention is directed to compositions comprising polymeric tertiary amines of urethane esters and salts thereof. The compositions are generally derived from linear or branched chain...
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7081246 |
Stable hydroalcoholic compositions
A hydroalcoholic lotion is disclosed which comprises (a) a lower alcohol and water in a weight ratio of about 35:65 to 100:0, and (b) between at least 0.5% and 8% by weight thickener system...
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7060259 |
Hydrolytically degradable carbamate derivatives of poly(ethylene glycol)
Poly(ethylene glycol) carbamate derivatives useful as water-soluble prodrugs are disclosed. These degradable poly(ethylene glycol) carbamate derivatives also have potential applications in...
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7041280 |
Aryl boronate functionalized polymers for treating obesity
Disclosed are polymers comprising one or more phenyl boronate ester, boronamide or boronate thioester groups. The phenyl boronate ester, boronamide and boronate thioester groups are represented by...
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7034061 |
Non-thrombogenic and anti-thrombogenic polymers
Polymers having non-thrombogenic properties can be prepared by copolymerizing monomers of at least three classes selected from (a) monomers having sulphate groups, (b) monomers having sulphonate...
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7030127 |
Composition and medical devices utilizing bioabsorbable polymeric waxes
The present invention is directed to medical devices, pharmaceutical or agricultural compositions, and seeds, each containing a synthetic, bioabsorbable, biocompatible polymeric wax that is the...
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7018644 |
Liquid air freshener and insecticidal compositions and device for using same
A non-aqueous, single phase, non-thickened liquid air freshener or insecticidal composition having a flashpoint of greater than about 62° C. is provided. The composition contains: a) a polar ...
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7008628 |
End modified thermal responsive hydrogels
A pharmaceutic composition includes a pharmaceutically acceptable carrier, comprising a reverse thermally viscosifying polymer. The polymer includes a linear block copolymer, wherein at least one...
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6994846 |
Composition for cosmetic or dermatological use containing a triblock polymer
The present patent application relates to a cosmetic and/or dermatological composition comprising at least one aqueous phase including at least one water-soluble or water-dispersible polymer, of...
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6890524 |
Hydrolyzable delivery system using cross-linked polymeric resins as vehicles
This invention provides a method of preparing a polymeric delivery system for active ingredients. The delivery system is formed either by attaching the active ingredient to a linker through a...
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6872384 |
Treatment of trauma
Provided is a method of treating an area affected by a trauma, such as a corneal wound or internal trauma, comprising administering to the affected area a trauma treating effective amount of a...
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6830747 |
Biodegradable copolymers linked to segment with a plurality of functional groups
Biocompatible biodegradable polymer or copolymer is capped at one end and has free hydroxyl at the other end. The free hydroxyl can be reacted to link a plurality of functional groups some or each...
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6824766 |
Biodegradable high molecular weight polymeric linkers and their conjugates
The present invention includes polymeric transport systems corresponding to the formula: wherein:R31 is a linear or branched polymer residue; Y10 and Y11 are independently O, S, or NR40; X2 is O, S...
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6811771 |
Bactericidal organic polymeric material
An object of the present invention is to provide a filter material capable of killing microorganisms, bacteria, fungi or viruses in air or liquids. Antimicrobial organic polymer materials of the...
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6805857 |
Method of modulating factor D, factor H and CD4 cell immune response with a polystyrene sulfonate, alginate, and saline infusion solution
Anthrax bio-terrorism is a poor man's nuclear bomb with devastating effects on the freedom and economy of any nation. No nation is immune. Urgently, there is a need for life saving technology that...
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6805872 |
Use in cosmetics of block ethylene copolymers with elastic character and compositions containing same
The invention relates to the cosmetic use of block ethylenic copolymers of elastic nature comprising at least one rigid block having a glass transition temperature (Tg) of greater than or equal to...
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6770285 |
Hydrophobic oil absorbing polymers and process
Hydrophobic, oil-absorbing polymeric compositions, prepared from high levels of hydrophobic monomers, are provided for transferring oily substances and hydrophobic materials to and from various...
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6746667 |
Adhesive treatment for tinea pedis
A method of treating or preventing tinea pedis, commonly known as Athlete's Foot, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to...
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6726905 |
Poly (diallylamines)-based phosphate binders
The present invention relates to a method for lowering the serum phosphate level of a patient. The method comprises the step of administering to the patient a therapeutically effective amount of a...
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6716455 |
Hair treatment gels containing itaconic acid monoester/acrylate copolymer
The aqueous hair fixing gel has special rheological properties so that it can be dispensed from a container without dripping or becoming stringy. It contains from 1.5 to 10 percent by weight of at...
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6716450 |
Enhancing protein activity through nanoencapsulation
Nanocapsules useful for encapsulating bioactive molecules such as proteins are disclosed. These nanocapsules are comprised of branched or hyperbranched polymers and copolymers and have a core-shell...
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6710122 |
Preparing aqueous polymer dispersions
A process for preparing aqueous polymer dispersions by means of a polymerization, conducted in an aqueous system, of at least one free-radically polymerisable ethylenically unsaturated monomer in...
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6706679 |
Use of copolymers on the basis of unsaturated acids or their derivatives as foam-protecting agent
The invention relates to the use of a copolymer or a mixture of copolymers as foam-protecting agents in detergent or cosmetic formulations, comprising at least one monomer (I) selected from the...
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6692734 |
N,O-amidomalonate platinum complexes
The present invention relates to purified platinum complexes in which platinum is coordinated to form a single N,O- or O,O-chelate of an amidomalonate. The chelates, and pharmaceutically acceptable...
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