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7220406 |
Method for promoting bone formation
Amine polymers, particularly aliphatic amine polymers, are useful in the treatment and prevention of bone disease and in methods for promoting bone formation. Sevelemer, polyallylamine crosslinked...
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7147845 |
Antimicrobial silver ion complex resinates
The present invention relates to novel antimicrobial silver ion complex resinates. More particularly, the present invention contemplates silver ion complex resinate compositions comprising a...
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7087223 |
Preventives and/or remedies for hyperphosphatemia
Provided in a phosphate ion adsorbent containing a weakly basic anion exchange resin as an active ingredient which aims at providing preventives and/or remedies for hyperphosphatemia having a high...
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7078050 |
Composition for topical treatment
A white cream bacteriostat and fungicide capable of serving as a vehicle for additional medicaments. Also disclosed is a method for blending the ingredients, some of which are not readily...
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7067116 |
Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer, such as pullulan, and a taste masked pharmaceutically active agent,...
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6899868 |
Iodine/resin disinfectant and a procedure for the preparation thereof
The present invention relates to iodine demand disinfectants. It relates in particular to a process for preparing a polyiodide-resin for use as an iodine demand disinfectant wherein a porous strong...
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6858203 |
Method of making phosphate-binding polymers for oral administration
Phosphate-binding polymers are provided for removing phosphate from the gastrointestinal tract. The polymers are orally administered, and are useful for the treatment of hyperphosphatemia.
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6844372 |
Crosslinked anion-exchange resin or salt thereof and phosphorus adsorbent comprising the same
An cross-linked anion exchange resin or a salt thereof obtained by reacting a polymer (A) having amino and/or imino groups in the total number of two or more per molecule with a compound (B) having...
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6726905 |
Poly (diallylamines)-based phosphate binders
The present invention relates to a method for lowering the serum phosphate level of a patient. The method comprises the step of administering to the patient a therapeutically effective amount of a...
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6702997 |
Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
The present invention relates to an albuterol inhalation solution, system, kit and method for relieving bronchospasm in children suffering from asthma. In one alternative embodiment, the solution...
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6692732 |
Ionic polymers as toxin-binding agents
A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the...
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6673338 |
Nitric oxide-releasing imidate and thioimidate diazeniumdiolates, compositions, uses thereof and method of making same
The invention provides NO— or NO − -releasing imidate, thioimidate, and amide diazeniumdiolates, in which the N 2 O 2 − functional group is bonded to a carbon atom. The invention also...
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6605270 |
Iron-binding polymers for oral administration
Iron binding polymers are provided for decreasing the absorption of iron from the gastrointestinal tract. The polymers are orally administered, and are useful for treatment of iron overload disorders.
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6592861 |
Iodinated resin held to a carrier
The present invention relates to iodine demand disinfectants. It relates in particular to a process for preparing a polyiodide-resin for use as an iodine demand disinfectant wherein a porous strong...
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6514492 |
Taste masking of oral quinolone liquid preparations using ion exchange resins
This invention relates to the formulation of oral liquid products of quinolones or derivatives thereof using ion exchange resins, such as methacrylic acid polymer crosslinked with divinylbenzene,...
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6497902 |
Ionically crosslinked hydrogels with adjustable gelation time
Biocompatible hydrogels, for: scaffoldings for tissue engineering; cell encapsulation matrices; injectable bulking materials for cosmetic and functional restorations; controlled release matrices;...
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6475478 |
Adsorbent, adsorbing and removing process and adsorber for endogenous cannabinoid
There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The...
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6294163 |
Polymers containing guanidinium groups as bile acid sequestrants
The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises administering a therapeutically effective...
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6277366 |
Release-sustaining agent for drugs and sustained-release pharmaceutical composition
A sustainedly releasing agent for medicines comprising a non-crosslinked type anion-exchange resin represented by the general formula (I): ##STR1## wherein R 1 represents aralkyl or alkyl, each of...
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6193962 |
Pharmaceutical formulation comprising a 2-aminoacetamide derivative and an ion exchange resin
The invention relates to novel formulations comprising a medicament and an ion-exchange resin.
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6180094 |
Remedies for hyperphosphatemia
A medicament which comprises as an active ingredient a weakly basic anion exchange resin chelating with ferric ions, preferably a polyamine-type or an acrylic-type resin. The medicament has...
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6132706 |
Methods of medical treatment for excess phosphate using guanidino-containing polymers
The invention provides a physiologically acceptable polymer comprising a backbone to which are attached guanidino groups, the polymer having a minimum molecular weight of 10,000. The invention also...
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6129910 |
Water-insoluble noncrosslinked bile acid sequestrants
The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises the step of orally administering to a...
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6071508 |
Preparation of formulations for electrotransport drug delivery
A method is provided for preparing drug formulations suitable for electrotransport drug delivery. The drug to be delivered, present in salt form, is contacted with an ion exchange material prior to...
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6063370 |
Macromolecular complexes for drug delivery
Novel macromolecular drug complexes containing a drug, like insulin, and a polymer having a plurality of acid moieties, like carboxyl moieties or phosphonic acid moieties, are disclosed....
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6036948 |
Polyaspartamide derivatives as adsordents for bile acids, polyaspartamide derivatives loaded with bile acids and process for their preparation and their use as pharmaceuticals
Polyaspartamide derivatives as adsorbents for bile acids, polyaspartamide derivatives loaded with bile acids and process for their preparation and their use as pharmaceuticals α- or β-linked...
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6022533 |
Tablets containing anion exchange resin
The present invention relates to a pharmaceutical composition comprising anion exchange resin, silicon dioxide, crystalline cellulose, and pharmaceutically acceptable carriers and more particularly...
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6015551 |
Copolymers of carboxylic acids and multiply olefinically unsaturated carboxylic acid derivatives and their use as thickeners and dispergents
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6007803 |
Ionic polymers as toxin binding agents
A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the...
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5980882 |
Drug-resin complexes stabilized by chelating agents
The invention provides a pharmaceutical composition comprising a drug-resin complex and a chelating agent in which the composition is in the form of a solid or a gel. The invention also provides a...
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5969090 |
Hydrophobic sequestrant for cholesterol depletion
The present invention relates to a poly(allylamine) polymer and, more generally, a hydrocarbon amine polymer. Preferably, these polymers are crosslinked. The present invention also relates to...
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5968499 |
Polymeric compounds
A polystyrene polymer crosslinked by 1.5% to 8% with divinylbenzene based on the total weight of the polymer and having a minimum weight average molecular weight of 10000 wherein 50 to 100% of the...
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5874522 |
Crosslinked polymeric ammonium salts
Disclosed are novel crosslinked polymeric ammonium salts wherein in said polymeric salt: about 25% or more of the segments which link ammonium nitrogen atoms are group Y wherein Y is an n-alkylene...
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5846525 |
Protected biopolymers for oral administration and methods of using same
The present invention provides a composition comprising an ion exchange resin and a therapeutically active biopolymer in a form for oral administration. The present invention also provides a...
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5800809 |
Non-crosslinked acrylic polymers and non-crosslinked anion exchange resins
The present invention provides a non-crosslinked acrylic polymer and a non-crosslinked anionic exchange resin consisting of polyacryloyloxyethyl-N,N-dimethylbenzyl ammonium salt.
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5726284 |
Crosslinked polymric ammonium salts
Disclosed are novel crosslinked polymeric ammonium salts wherein in said polymeric salt: about 25% or more of the segments which link ammonium nitrogen atoms are group Y wherein Y is an n-alkylene...
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5714138 |
Polyaspartamide derivatives as adsorbents for bile acids, polyaspartamide derivatives loaded with bile acids and process for their preparation and their use as pharmaceuticals
Polyaspartamide derivatives as adsorbents for bile acids, polyaspartamide derivatives loaded with bile acids and process for their preparation and their use as pharmaceuticals α - or β-linked...
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5709880 |
Method of making tabletized ionene polymers
Tabletized ionene polymers, methods for their preparation and their use in water treatment is described. The tablet contains about 5 to about 60 percent by weight of an ionene polymer, about 40 to...
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5683709 |
Poly(benzalkonium salt) as an anti-microbial agent for aqueous drug compositions
A package containing an aqueous drug composition containing an insoluble resin comprising benzalkonium salt units in an amount sufficient to inhibit growth of microbes in said aqueous drug...
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5643560 |
Drug formulation with ion-exchangers
The invention relates to the use of, and methods to obtain, ion exchanger complexes with psychotropic drugs for reducing toxic side effects and lethality when overdosing the drug. The invention...
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5635172 |
Sustained release comfort formulation for glaucoma therapy
Disclosed are nonstinging, sustained release ophthalmic formulations to control intraocular pressure in antiglaucoma therapy comprising a basic active, a cation exchange resin, and, inter alia, an...
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5618530 |
Hydrophobic amine polymer sequestrant and method of cholesterol depletion
An amine polymer includes a substituent bound to an amine of the polymer. The substituent includes a quaternary amine-containing moiety having at least one hydrophobic moiety. A method for binding...
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5589166 |
Cross-linked quaternary ammonium derivatives of poly(N,N-dialkylallyl) ammonium polymers
The invention concerns novel cross-linked poly(N,N-dialkylallyl)ammonium polymer materials containing quaternary propylammonium structural units which are effective in lowering elevated plasma...
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5500212 |
Crosslinked anion exchange particles and method for producing the particles
New bile acid sequestrant polymer compositions and a process for preparing the polymers in particulate form, preferably in spherical form, are described. The polymer particles are prepared by...
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5451397 |
Bile acid sequestrant
A bile acid sequestrant having a crosslinked polymeric matrix and having branches supported on the polymeric matrix and providing bonding sites for binding bile acid conjugates to the sequestrant,...
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5447717 |
Cholesterol-lowering agents
This invention relates to compounds of structural formula (I): ##STR1## which are squalene synthase inhibitors and thus useful as cholesterol lowering agents and antifungal agents. These compounds...
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5374422 |
Ingestible [hydrophobic] polymeric amines useful for lowering blood cholesterol
The invention is concerned with novel ingestible cross-linked homopolymers having functional groups consisting of linear or branched amines, of the formula: ##STR1## and their pharmaceutically...
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5368852 |
Prolonged-release liquid type of pharmaceutical preparation comprising drug-resin complex and benzoate preservative
The present invention provides a prolonged-release liquid type of pharmaceutical preparation prepared by coating a pharmaceutically active drug-ion exchange resin complex which was treated...
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5366724 |
Ingestible polymeric amines for the lowering of blood cholesterol
The invention is concerned with novel ingestible polymeric amines in linear or branched form of the formula: ##STR1## and their pharmaceutically acceptable salts of the formulae: ##STR2## wherein P...
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5334378 |
Pharmaceutical formulation in the form of aqueous suspension
A pharmaceutical formulation in the form of aqueous suspension which comprises an ion exchange resin carrying an active ingredient and a suspending agent, characterized in that the formulation...
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