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8173114 |
Excretion accelerator for accumulative chlorine compound
An agent for promoting excretion of an accumulative chlorine compound comprising a pharmaceutically acceptable anion exchange resin, which is a novel agent that is for promoting the excretion of an...
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8119125 |
Compositions and methods for enhanced gastrointestinal stability of oligopeptides and polypeptides
Methods and compositions are provided for stabilizing polypeptides for oral administration, particularly where enteric delivery is desirable. By administering the polypeptides with a bile...
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8106016 |
Compounds and compositions for prevention of overdose of oxycodone
The invention relates to pharmaceutical compounds and compositions comprised of a chemical moiety attached to an opioid such as oxycodone in a manner that substantially decreases the potential of...
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7955997 |
Electrostatically charged filter media incorporating an active agent
There is provided a protective media and a method of manufacturing the same. In one aspect, the protective media includes a porous dielectric carrier, an active agent incorporated in the porous...
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7854924 |
Methods and compositions for treatment of ion imbalances
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodium-binding polymers and pharmaceutical...
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7815898 |
Oral compositions for absorption of phosphorus compounds
The present invention provides medicaments useful for reducing phosphorus serum level, especially in those subjects affected from hyperphosphatemia. More specifically, the present invention relates...
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7811555 |
Tri-branched biologically active copolymer
The present invention discloses a tri-branched copolymer comprising a hydrophobic domain, a hydrophilic domain, a biologically active moiety, and an alkyl core of 2 to 10 carbon atoms. The...
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7794698 |
Composition and methods for cell killing
A method of generating a change in a cellular process of a target cell is disclosed. The method comprises contacting the target cell with a solid buffer, so as to alter an intracellular pH value in...
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7776319 |
Methods and compositions for treatment of ion imbalances
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising sodium-binding polymers and pharmaceutical...
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7749536 |
Pharmaceutical formulations of aliphatic amine polymers and methods for their manufacture
The present invention provides pharmaceutical compositions comprising aliphatic amine polymers such as for example Sevelamer HCl as the active pharmaceutical ingredient, wherein the aliphatica...
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7678369 |
Anionic polymers as toxin binders and antibacterial agents
The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of...
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7662364 |
Drug for hyperphospheremia and its preparative method
This invention reports a drug for hyperphospheremia and its preparative method. The preparation includes active constituents, lanthanum polystyrene sulfonate, and excipients. The preparative method...
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7553482 |
Use of a phosphate adsorbent to combat vascular diseases
The invention relates to the use of an adsorption material which has been modified with polynuclear metal oxide hydroxides for influencing the calcium level and, in particular, for treating or/and...
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7541024 |
Low salt forms of polyallylamine
Disclosed is a pharmaceutical composition comprising a stable polyallylamine hydrochloride polymer in which between about 4% to about 12% by weight of the polymer is a chloride anion and a...
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7459151 |
Phosphate-binding polymers for oral administration
Phosphate-binding polymers are provided for removing phosphate from the gastrointestinal tract. The polymers are orally administered, and are useful for the treatment of hyperphosphatemia.
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7399821 |
Alkylated poly(allylamine) polymers and methods of use
The invention relates to a method for removing bile salts from a patient in need thereof and compositions useful in the method. The method comprises administering to the patient a therapeutically...
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7220406 |
Method for promoting bone formation
Amine polymers, particularly aliphatic amine polymers, are useful in the treatment and prevention of bone disease and in methods for promoting bone formation. Sevelemer, polyallylamine crosslinked...
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7199160 |
Antiobestic agents and health foods
Antiobestic agents and health foods containing as the active ingredient substances having an effect of adsorbing bile acid in the digestive tract, an effect of inhibiting intestinal circulation or...
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7153497 |
Controlled dissolution of active ingredients
A dosage form comprising a resin/resinate combination is described. Said dosage form allows optimization of the release rate profile of active ingredients.
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7147845 |
Antimicrobial silver ion complex resinates
The present invention relates to novel antimicrobial silver ion complex resinates. More particularly, the present invention contemplates silver ion complex resinate compositions comprising a...
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7087223 |
Preventives and/or remedies for hyperphosphatemia
Provided in a phosphate ion adsorbent containing a weakly basic anion exchange resin as an active ingredient which aims at providing preventives and/or remedies for hyperphosphatemia having a high...
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7067116 |
Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer, such as pullulan, and a taste masked pharmaceutically active agent,...
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7033583 |
Polymeric thiol-linked prodrugs
Thiol-linked polymeric prodrugs and methods of making and using the same are disclosed. The use of a sulfhydryl bond as the basic link for linking the polymer to the drug allows a prodrug to be...
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7014845 |
Crosslinked copolymers based on non-crosslinked polycarboxylic copolymers
The invention relates to cross-linked copolymers based on non cross-linked polycarboxylic copolymers, said non cross-linked copolymers containing at least one polysaccharide. The invention also...
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6992061 |
Purification method
The invention relates to a method of removing endotoxin from preparation of alpha-1-acid glycoprotein (orosomucoid) by contact with a finely divided non-toxic resin such as fumed silica. The...
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6989150 |
Cosmetic preparation of active substances with a synergistically increased radical protection factor
The inventive cosmetic preparation of active substances, as such as well as in combination with other active substances, protects the skin against free radical aggression in a particularly...
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6955806 |
Ionene polymers and their use as antimicrobial agents
Disclosed are ionene polymers having antimicrobial activity. “Ionene polymers” as used in this invention are cationic polymers in which a substantial proportion of the atoms providing the pos...
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6951953 |
Tumor selective and biodegradable polyphosphazene-platinum(II) conjugate antitumor agent, and preparation method thereof
Disclosed are a new class of a polyphosphazene-platinum(II) conjugate antitumor agent having high tumor tissue selectivity due to its enhanced permeability and retention effect to tumor tissues,...
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6916481 |
Active-substance vector multiparticulate system, production and use thereof
The invention relates to an active substance vector multiparticulate system and to the production and use thereof. The object of the invention is an active-substance vector multiparticulate system...
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6899868 |
Iodine/resin disinfectant and a procedure for the preparation thereof
The present invention relates to iodine demand disinfectants. It relates in particular to a process for preparing a polyiodide-resin for use as an iodine demand disinfectant wherein a porous strong...
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6844372 |
Crosslinked anion-exchange resin or salt thereof and phosphorus adsorbent comprising the same
An cross-linked anion exchange resin or a salt thereof obtained by reacting a polymer (A) having amino and/or imino groups in the total number of two or more per molecule with a compound (B) having...
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6734223 |
Polyaminoester and their application in dental compositions
Dental compositions comprising at least a polymerizable monomer and/or at least a polyaminoester that are prepared by reaction of bis- or polyacrylic esters and amines, pigments, organic and/or...
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6723344 |
Controlled release of non heparin-binding growth factors from heparin-containing matrices
Matrices that support cell adhesion and growth are disclosed that deliver low heparin-binding affinity growth factor protein peptides in a controlled manner. These matrices comprise covalently or...
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6703013 |
Polystyrene sulfonate-containing gel preparation
The invention relates to a polystyrene sulfonate-containing gel preparation for therapy of hyperpotassemia, wherein the particle size of polystyrene sulfonate is controlled within the range of at...
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6696055 |
Method and system for treating air with an iodinated resin
The present invention relates to a method for treating air with an iodinated resin to remove contaminants contained in the air. The iodinated resin is an iodinated anion exchange resin. The present...
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6692732 |
Ionic polymers as toxin-binding agents
A method for treating pathogenic toxins in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising a cationic group attached to the...
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6667058 |
Oral forms of administration containing solid flupirtine with controlled release of active substance
Pharmaceutical dosage units containing flupirtine or a pharmaceutically acceptable salt of flupirtine with controlled release of active substance using a delayed-action or controlled-release...
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6592861 |
Iodinated resin held to a carrier
The present invention relates to iodine demand disinfectants. It relates in particular to a process for preparing a polyiodide-resin for use as an iodine demand disinfectant wherein a porous strong...
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6534282 |
Detection of hypertension using immunoreactive metabolic products
A method to assess hypertension by measuring the amount of free and conjugated hydroxyeicosatrienoic acids (DHETs) and metabolites of DHETs, which are metabolites of arachidonic acid (AA)...
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6531519 |
Antimicrobial synthetic ion exchange resins
A method of preventing the growth of heterotrophic bacteria and the subsequent establishment of a biofilm on the surface and in the micropores of an antimicrobial synthetic ion exchange resin. An...
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6524569 |
Anionic-cationic polyion complexes comprising zwitterionic monomer component
A polyion complex (PIC) is formed of an anionic soluble polymer formed from ethylenically unsaturated monomers including at least one anionic or monomer and a cationic soluble polymer formed from...
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6521257 |
Gelled compositions
A gelled composition was provided by adding a gelling component to a carrier for adsorption. Not only was the taste of the carrier for adsorption significantly reduced in this composition, but the...
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6521265 |
Method for applying a blood clotting agent
A method of arresting the flow of blood and other protein containing body fluids flowing from an open wound and for promoting wound healing. In the method, a substantially anhydrous compound of a...
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6517826 |
Anionic polymers as toxin binders and antibacterial agents
The present invention relates to a method of inhibiting a toxin in an animal, such as a human, by administering to the animal a therapeutically effective amount of a polymer having a plurality of...
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6514492 |
Taste masking of oral quinolone liquid preparations using ion exchange resins
This invention relates to the formulation of oral liquid products of quinolones or derivatives thereof using ion exchange resins, such as methacrylic acid polymer crosslinked with divinylbenzene,...
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6488924 |
Vitamin K adduct, particularly suitable as vitamin supplement for feeds
A vitamin K adduct, particularly suitable as vitamin supplement for feeds, constitued by menadione bisulfite bonded with an appropriate ion-exchange resin and exceptionally stabilized thereby. The...
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6469035 |
Methods of pretreating hyperlipidemic individuals with a flush inhibiting agent prior to the start of single daily dose nicotinic acid therapy to reduce flushing provoked by nicotinic acid
The present invention relates to pretreating individuals with an effective amount of a flush inhibiting agent for a sufficient period of time prior to the start of single daily dose nicotinic acid...
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6447764 |
Method for isolating anionic organic substances from aqueous systems using cationic polymer nanoparticles
The invention relates to a method for isolating anionic organic substances from aqueous systems using polymer nanoparticles with cationic pH-sensitive surface groups. Extraction can be carried out...
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6361768 |
Hydrophilic ampholytic polymer
A novel hydrophilic ampholytic polymer synthesized by reacting polymerizable amino and carboxy functional ethylenically unsaturated monomers, together with a non-ionic hydrophilic monomer, to...
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6358501 |
Polypeptide-polysiloxane copolymers
The present invention relates to polypeptide-polysiloxane copolymers, to their preparation by thermal copolymerization of amino acids with organofunctional polysiloxanes, and to their use as...
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