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7381404 |
Treatment for dry macular degeneration
The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any...
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7364723 |
Liquid preparation for contact lenses
A highly safe liquid preparation for contact lenses which contains 0.3 to 50 ppm of a polyamine having recurring units of the formula (I):
wherein n is 0 or 1, and which has a high...
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7363928 |
Dilution resistant viscoelastic compositions
A method of performing intra-articular therapy and a dilution resistant viscoelastic composition are disclosed. One embodiment of the dilution resistant composition comprises a hyaluronate-based...
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7354574 |
Treatment of ocular disease
A method and article to treat ocular disease with Cyclosporin A alone or with compounds related to Cyclosporin A for intraocular injection or implantation. Treatment does not result in ocular...
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7351407 |
Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (CTGF) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies
The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least...
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7332470 |
Methods and compositions for treating ocular disease
The use of collectins and/or surfactant proteins for the treatment and prevention of ocular disease.
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7306802 |
Ophthalmic compositions containing a synergistic combination of three polymers
Ophthalmic compositions suitable for use as artificial tears or as vehicles for ophthalmic drugs are disclosed. The compositions contain a combination of three polymers that have a synergistic...
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7232568 |
Compositions and methods for treating hyperimmune response in the eye
The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination...
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7147844 |
System for stabilizing lacrimal fluid layer
A purpose of the present invention is to remove dryness and unpleasantness in eyes of contact lens wearers and to obtain favorable moist feel and wearing feel by stabilizing a lacrimal fluid layer...
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7141607 |
Methods and compositions for treating and inhibiting retinal neovascularization
Methods and compositions for the prophylactic and therapeutic treatment of retinal disorders associated with neovascularization using topical ophthalmic compositions comprising hydroxamic acid...
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7128928 |
Ophthalmic formulation with novel gum composition
There is provided a pharmaceutical composition suitable for topical administration to an eye, the composition comprising (a) a pharmacologically effective concentration of an active agent and (b) a...
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7115263 |
Compositions and methods for treating hyperimmune response in the eye
The present invention comprises and utilizes methods and compositions for treating hyperimmune reactions in the eye. Compositions comprising antibodies to gamma interferon alone and in combination...
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7105473 |
Compositions and methods using sub-PPM combinations of polyquaternium-1 and high molecular weight PHMB
Multi-purpose solutions for contact lens care provide substantial lens wearer/user comfort and/or acceptability, with minimal, if any, corneal epithelial punctate fluorescein staining. Such...
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7101564 |
Plastically deformable implant
The invention relates to a plastically deformable implant for inserting into bodily orifices of the human or animal body. Implants of this type are used, for example, in ophthalmology, in...
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7087222 |
Method for enhancing integrity of epithelium using retinoic acid
A method for improving the integrity of the corneal epithelium by introducing into the eye an effective amount of a ophthalmically compatible retinoid sufficient to enhance the integrity of the...
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7063857 |
Use of macrolide compounds for the treatment of dry eye
The present invention provides an agent for treating a dry eye, which contains a macrolide compound such as FK506.
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7060297 |
Carrageenan viscoelastics for ocular surgery
Disclosed are carrageenan-based transitional viscoelastics that will induce little or no IOP spike when left in the eye at the close of surgery thereon. Drug delivery systems for delivering...
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7056495 |
Solid dose delivery vehicle and methods of making same
The present invention encompasses a solid dose delivery vehicle for ballistic administration of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being sized and...
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7045121 |
Ophthalmic compositions for lubricating eyes and methods for making and using same
Ophthalmic compositions include an ophthalmically acceptable carrier component, for example, an aqueous-based carrier, and a plurality of polyanionic component portions having different molecular...
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7045095 |
Use of low molecular weight amino alcohols in ophthalmic compositions
The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
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7025958 |
Use of amidoamines to treat or prevent acanthamoeba and fungal infections
The use of amidoamines to treat or prevent infections attributable to Acanthamoeba and fungi is described. The amidoamines are highly effective against both Acanthamoeba and fungi, and are less...
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7018646 |
Apparatus and method for delivering controlled quantities of one or more agents to the eye
A flat strip of supporting material, such as filter paper, having marked reference locations on each of one or more legs, for delivering controlled quantities of one or more agents to the adnexa of...
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7001607 |
Artificial tear replacement solution
A tear replacement solution that contains at least one water-soluble fluorosurfactant, water and a non-polar component, preferably in gel form, and a method for the external treatment for the eye...
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6998426 |
Nanoemulsion containing nonionic polymers, and its uses
These objects and others may be accomplished with the present invention, the first embodiment of which provides an oil-in-water nanoemulsion, which includes:
an oily phase dispersed in an...
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6995123 |
Use of multifunctional surface active agents to clean contact lenses
Cleaning compositions for contact lenses are described. The compositions contain multifunctional anionic surfactants that include at least two hydrophilic dissociating head groups. The...
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6984394 |
Plastically deformable implant
The invention relates to a plastically deformable implant for inserting into bodily orifices of the human or animal body. Implants of this type are used, for example, in ophthalmology, in...
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6962693 |
Alkylpolypropyleneoxide amidotriamines and method of using same
Alkylpolypropyleneoxide amidotriamines having antimicrobial activity are described. The compounds are useful as antimicrobial preservatives in various types of pharmaceutical compositions....
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6949241 |
Use of lacrophyl preparation in eye drops containing therapeutically active compounds
The invention refers to the use of a lacrophyl preparation containing lysozyme, tris(hydroxymethyl)aminomethane, if desired other lacrophyl components, preferably ascorbic acid and/or citric acid...
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6949218 |
Use of low molecular weight amino alcohols in ophthalmic compositions
The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
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6936640 |
Biguanide/quaternary ammonium containing copolymeric biocides and use thereof in pharmaceutical compositions
Biguanide/quaternary ammonium compounds and the use of same as antimicrobial agents in pharmaceutical compositions are described. The biguanide/quaternary ammonium compounds are useful in the...
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6930077 |
Compositions and methods using sub-PPM combinations of polyquaternium-1 and high molecular weight PHMB
Multi-purpose solutions for contact lens care provide substantial lens wearer/user comfort and/or acceptability, with minimal, if any, corneal epithelial punctate fluorescein staining. Such...
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6923955 |
Presbyopia treatment by lens alteration
This invention effects a change in the accommodation of the human lens affected by presbyopia through the use of various reducing agents that change accommodative abilities of the human lens,...
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6902548 |
Use of Streptomyces hyalurolyticus enzyme in ophthalmic treatments
A highly specific and easily purified form of hyaluronidase is described for use in ophthalmic treatments. The enzyme, from Streptomyces hyalurolyticus is specific for hyaluronidase and carries...
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6893657 |
Solid dose delivery vehicle and methods of making same
The present invention encompasses a solid dose delivery vehicle for ballistic administration of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being sized and...
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6872383 |
Use of macrolide compounds for the treatment of dry eye
The present invention provides an agent for treating a dry eye, which contains a macrolide compound such as FK506.
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6872382 |
Use of selective PDE IV inhibitors to treat dry eye disorders
Selective PDE-IV inhibitors are useful for treating dry eye disorders and other disorders requiring the wetting of the eye.
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6852311 |
Ophthalmic ointments for treating infective eye disease
Ophthalmic ointments for treating infective eye diseases which are particularly effective against infective eye diseases caused by methicillin-resistant Staphylococcus aureus (MRSA) or...
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6849253 |
Use of borate-polyol complexes in ophthalmic compositions
Water-soluble borate-polyol complexes are useful as buffers and/or antimicrobials in aqueous ophthalmic compositions, including those containing polyvinyl alcohol. These compositions have greater...
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6841146 |
Spray composition
An aqueous-based sprayable composition comprises a therapeutic or palliative agent, water and a mixture of microcrystalline cellulose and alkali metal carboxyalkylcellulose. In one embodiment, the...
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6833358 |
Lacrimal secretion promoters or eye drops for treating keratoconjunctival failure containing as the active ingredient natriuretic peptides
The object of the present invention is to find new effects of natriuretic peptides in an ophthalmological field. The present invention provides eyedrops for promoting lacrimal secretion or for...
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6824762 |
Nasal spray compositions
Aqueous nasal spray compositions comprising a medicament and an aqueous carrier comprising water soluble polymers selected from the group consisting of polyvinylpyrrolidone and mixtures thereof.
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6787131 |
Method for enhancing integrity of epithelium using retinoic acid
A method for improving the integrity of the corneal epithelium by introducing into the eye an effective amount of a ophthalmically compatible retinoid sufficient to enhance the integrity of the...
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6776982 |
Autoclavable pharmaceutical compositions containing a chelating agent
Disclosed are ophthalmic compositions comprising ketotifen and pharmaceutically acceptable salts thereof, as well as methods for making such compositions.
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6749844 |
Magnetic fluids
A magnetic fluid is provided comprising a block copolymer stabilizer, magnetic particles and a fluid polysiloxane medium. The stabilizer comprises an anchor block which chelates magnetic metal...
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6737075 |
Biochemical methods that eliminate corneal scars, opacification and haze
The invention disclosed herein relates to biochemical methods for the elimination of corneal collagen fiber disorganization to improve vision. Disorganization of corneal collagen fibers is seen in...
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6713081 |
Ocular therapeutic agent delivery devices and methods for making and using such devices
Ocular implant devices for the delivery of a therapeutic agent to an eye in a controlled and sustained manner. Dual mode and single mode drug delivery devices are illustrated and described....
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6656460 |
Method and composition for dry eye treatment
A method and composition for treating a dry eye condition by topically applying to the eye surfaces an emulsion forming a tear film that acts to lubricate the eye and to inhibit evaporation...
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6630135 |
Use of sustained release antibiotic compositions in ophthalmic surgical procedures
An improved method of sterilizing the field of surgery prior to an ophthalmic surgical procedure is described. The invention eliminates the need for painful and potentially traumatic injections of...
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6627620 |
Composition set and kit for use in intraocular surgery
A new composition set and a kit for use by intraocular operations, preferably cataract operations. The composition set comprises a first and a second viscoelastic agent, e.g. sodium hyaluronate,...
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6624203 |
Nucleic acid bases used in ophthalmic solutions
An ophthalmic solutions that are broad ranged and effective in low concentrations relative to state of the art systems. In particular it has been found that ophthalmic solutions comprising 0.00001...
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