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7611733 |
Nanoparticle formulations of platinum compounds
Solid Lipid Nanoparticles of platinum compounds, particularly of antitumor platinum complexes are disclosed. The Nanoparticles of the invention are obtained by a process comprising: a) preparing a...
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7578997 |
Metal ion modified high surface area materials for odor removal and control
This invention relates to high surface area materials, such as nanoparticles, that are coated with metal ions. These modified nanoparticles have active sites that bind various gases and/or odorous...
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7537786 |
Complex of drug-carbon nanohorn and a process for producing the complex
The present invention provides a carbon nanohorn complex that is excellent in characteristics of adsorption or inclusion of drugs and release, in particular, a sustained release of drugs as a novel...
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7514442 |
Trisubstituted 4-aminopyrazolopyrimidines as cyclin dependent kinase inhibitors
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds,...
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7470714 |
GM-95-containing antitumor effect potentiator, combined antitumor preparation and antitumor agent
An antitumor effect enhancer for enhancing the antitumor effects of an antitumor substance, which comprises a compound represented by the following formula (1):
wherein each R independently...
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7470695 |
N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds,...
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7465754 |
Method of potentiating chemotherapy and treating solid tumors
This invention provides a method of treating solid tumors which comprises administering an effective amount of a combination of (1) a bioresponse modifier and (2) a chemotherapeutic agent. This...
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7452554 |
Platinum nanocolloid solution, process for producing the same and drink containing platinum nanocolloid
A nanocolloidal platinum dispersion comprising nanocolloidal platinum and a polyacrylic acid salt, the nanocolloidal platinum having an average particle size of 1-5 nm, 90% or more of the...
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7445799 |
Compositions for microbial and chemical protection
An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and...
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7445764 |
Carrier-drug conjugate
The invention relates to a carrier-drug conjugate comprising a carrier containing a polypeptide sequence having one or several cysteine radicals and a pharmacon containing a pharmaceutical and/or...
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7427416 |
Methods of treating conditions using metal-containing materials
Methods of treating conditions using metal-containing materials are disclosed. Exemplary conditions include bacterial conditions, biofilm conditions, microbial conditions, inflammatory conditions,...
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7422121 |
Process for producing a sterilization system
The invention relates to a method for producing a sterilisation system, especially for sterilising drinking water and water for industrial use. The precious metal surface of a base material...
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7410655 |
Anticancer agent
An anticancer agent containing platinum preparation, humic substances, water and sodium chloride. Potassium tetrachloroplatinate is used as a platinum compound and lignohumic acid ammonium salts...
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7387790 |
Pharmaceutical and diagnostic compositions containing nanoparticles useful for treating targeted tissues and cells
Nanoparticles made from a select group of lipids and optionally containing a therapeutically active agent are employed in pharmaceutical compositions for delivery to targeted tissues and/or cells...
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7371411 |
Methods for production of the oxidized glutathione composite with CIS-diamminedichloroplatinum and pharmaceutical compositions based thereof regulating metabolism, proliferation, differentiation and apoptotic mechanisms for normal and transformed cells
The present invention relates to a composite for the treatment of a variety of medical conditions, the composite comprising an oxidized glutathione-based compound, which has a disulfide bond, and a...
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7357949 |
Encapsulated inorganic antimicrobial additive for controlled release
The invention relates to a microcapsule comprising an inorganic antimicrobial agent coated with a hydrophilic polymer. The hydrophilic polymer is able to absorb sufficient water as to enable the...
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7354605 |
Antimicrobial medical device
According to the present invention there are provided antimicrobial catheters and other medical devices having controlled release of an antimicrobial metal or metal ion. Specifically, antimicrobial...
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7345046 |
Heteroaryl-fused pyrimidinyl compounds as anticancer agents
Heteroaryl-fused pyrimidinyl compounds, pharmaceutically acceptable salts, and prodrugs thereof; compositions that include a pharmaceutically acceptable carrier and one or more of the...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7255881 |
Metal-containing materials
Metal-containing materials, as well as their preparation and use are disclosed. The metal-containing material can be, for example, an antimicrobial material, an anti-biofilm material, an...
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7238372 |
Methods for inhibiting tumor cell proliferation
The subject invention concerns methods for inhibition of STAT biological functions using platinum complexes.
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7226608 |
Topical use of microfine calcined alumina
Dispersions containing from about 0.5% to about 30% by weight dispersed microfine calcined alumina, stainless steel, or gold particles typically having particle size of less than about 5μ, more...
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7201925 |
Treatment of ungual and subungual diseases
The treatment of ungual and subungual diseases is disclosed.
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7175741 |
Reducing odor in absorbent products
Hydrogen sulfide is removed or reduced in absorbent products by the use of a particulate material attached to pulp fiber by a retention aid. The particulate material can remove or reduce the...
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7163703 |
Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds
The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt,...
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7097858 |
Polyoxometalate materials, metal-containing materials, and methods of use thereof
Polyoxometalate topical compositions for removing contaminants from an environment and methods of use thereof are disclosed. An embodiment of the polyoxometalate topical composition includes a...
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7087249 |
Treatment of mucosal membranes
The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and...
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RE39150 |
Composition for creating vascular occlusions
A composition including 2-hexyl cyanoacrylate and goal is useful in treating arteriovenous malformations (AVMs) and other body lumens to be blocked.
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7029696 |
Delivery and activation through liposome incorporation of diaminocyclohexane platinum(II) complexes
Antitumor compositions are disclosed, as well as methods of preparing the compositions and methods of using them to inhibit tumor growth in mammals. The invention can take advantage of...
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7015251 |
Combinations of ceramide and chemotherapeutic agents for inducing tumor cell death
This invention provides a method for increasing apoptosis in tumor cells and a method of decreasing a size of a tumor, said methods comprising contacting the tumor cells with: a) an effective...
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7008647 |
Treatment of acne
The invention relates to the use of one or more antimicrobial metals selected from silver, gold, platinum, and palladium but most preferably silver, preferably formed with atomic disorder, and...
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7005145 |
Antibacterial and fungicidal polymer dispersions and polymer solutions
The invention relates to polymer dispersions or polymer solutions that are given antibacterial and fungicidal properties by metal ions of group Ib of the Periodic table. According to the invention,...
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7001617 |
Method of induction of apoptosis and inhibition of matrix metalloproteinases using antimicrobial metals
The invention relates to a method to induce apoptosis and to inhibit matrix metalloproteinases in a disease condition in a human or animal by contacting hyperplastic tissue, tumor tissue, or a...
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6992106 |
Anti-tumor composition
The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors,...
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6989158 |
Gold-containing chemotherapeutic agents
There is provided a complex for use as a therapeutic pharmaceutical, the complex has a ligand containing at least one hydroxyalkyl phosphine donor group bound to a gold atom to form a stable...
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6989157 |
Dry powders of metal-containing compounds
Dry powders of metal-containing compounds are disclosed. Methods of preparing and using the dry powders, particularly in the treatment of a subject having a condition, are also disclosed. The...
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6989156 |
Therapeutic treatments using the direct application of antimicrobial metal compositions
Therapeutic treatments using the direct application of selected structures of antimicrobial metals in free-standing powder form, solution form and/or suspension form in therapeutically effective...
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6974798 |
Treatment of balance impairments
Compositions and methods are provided for prophylactic or therapeutic treatment of balance impairments involving neuronal damage, loss, or degeneration, preferably of vestibular ganglion neurons,...
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6960596 |
Composition comprising camptothecin or a comptothecin derivative and a platin derivative for the treatment of cancer
The present invention relates to therapeutic associations for the treatment of cancer, comprising an effective amount of a camptothecin, or a camptothecin derivative, with an effective amount of an...
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6939568 |
Treatment of inflammatory skin conditions
The invention relates to the use of one or more antimicrobial metals, most preferably silver, preferably formed with atomic disorder, and preferably in a nanocrystalline form, for the treatment of...
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6939566 |
Microbicidal formulations and methods to control microorganisms
Microbicidal formulations are described which are preferably ecologically friendly and non-toxic to mammals, and are highly effective against a broad spectrum of detrimental pathogenic...
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6933320 |
Combination comprising combretastatin and anticancer agents
An antitumor combination comprising a stilbene derivative and an anticancer compound selected from the group consisting of taxanes, alkylating agents, antimetabolites, vinca alkaloids, platinum...
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6905711 |
Antimicrobial agents, products incorporating said agents and methods of making products incorporating antimicrobial agents
An antimicrobial agent includes an oligodynamic metal ion in a hydrophilic polymer binder or carrier. According to a presently preferred embodiment, the metal ion is silver and the hydrophilic...
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6900239 |
Tumor chemopotentiation using isocoumarin derivatives
A method for enhancing the efficacy of chemotherapy in the treatment of cancer in animals, particularly humans, is provided wherein isocoumarin derivatives that exhibit unique chemopotentiation...
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6884817 |
Water soluble paclitaxel derivatives
Disclosed are water soluble compositions of paclitaxel and docetaxel formed by conjugating the paclitaxel or docetaxel to a water soluble polymer such as poly-glutamic acid, poly-aspartic acid or...
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6844012 |
Use of selenium for treating patients suffering from systemic inflammatory response syndrome (SIRS), and composition for implementing said treatment
The invention concerns the use of at least a molecule containing selenium, in an amount corresponding to a daily dose of about 2 to 40 mg, even 80 mg of atomic selenium equivalent, on its own or...
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6833362 |
Method and composition for the accelerated in vivo removal of ethanol
A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or...
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6770673 |
Therapeutic uses of arglabin in combination with other chemotherapy agents
Compositions and kits containing a first chemotherapeutic agent that includes arglabin or a derivative thereof and a second chemotherapeutic agent are described. The compositions and kits are...
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6764692 |
Method to treat laminitis and reduce dietary intake for horses
A method of treating laminitis in a horse is disclosed, comprising administering to the horse a naturally chelated trace mineral composition; promoting healthy skin, hair and hoof tissue. A method...
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6751280 |
Method of preparing high specific activity platinum-195m
A method of preparing high-specific-activity 195m Pt includes the steps of: exposing 193 Ir to a flux of neutrons sufficient to convert a portion of the 193 Ir to 195m Pt to form an irradiated...
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