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7622562 |
Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
A method for purifying bone-derived osteoinductive proteins including a demineralization process, a protein extraction process, a high molecular weight ultrafiltration process, a low molecular...
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7608284 |
Enamel matrix protein composition for treatment of systemic inflammatory response syndrome
The present invention relates to the use of a preparation of an active enamel matrix substance, such as an amelogenin, for the manufacture of a pharmaceutical composition for modulating an immune...
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7534419 |
Methods of diagnosis and treatment of osteoporosis
A method of detecting osteoporosis in a mammalian is disclosed herein which includes:
a) obtaining a sample of a bone related tissue or cells; and b) measuring the concentration of at least a...
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7534264 |
Delivery system for bone growth promoting material
A delivery system that includes a bone growth promoting material encapsulated within a water absorptive gelatinizable covering is used to promote bone growth in order to repair a bone defect and/or...
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7527799 |
ENA mineral bioactive solution, manufacturing method thereof and its application for the osteoporosis prevention
The present invention is related to a method of manufacture of an alkaline mineral bioactive solution of which raw materials are squid bones burnt at a high temperature and crushed powder of red...
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7399739 |
Vertebral augmentation composition and method
A flowable vertebral augmentation composition for the treatment and repair of a vertebral body defect, e.g., an osteoporotic condition, contains biocompatible, optionally osteoconductive, support...
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7371408 |
Bone graft substitute composition
A bone graft substitute composition comprising calcium sulfate; a mixing solution selected from the group consisting of sterile water, sodium chloride, phosphate buffered saline, potassium...
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7341999 |
Povidone-containing carriers for polypeptide growth factors
A liquid carrier medium is provided which is suitable for solubilizing growth factors, such as mixtures of bone morphogenetic proteins, that are found to induce an angiogenic response in ischemic...
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7335381 |
Transplantable particulate bone composition having high osteoinductive capacity and methods for making and using same
A particulate bone of defined sizes which has a unique property of direct bone osteoinduction without going through endochondral ossification stage is disclosed. The bone is not subjected to...
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7323193 |
Method of making demineralized bone particles
Demineralized bone particles are obtained by demineralizing whole bone and thereafter subdividing the demineralized bone to provide the demineralized bone particles.
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7316822 |
Conformable tissue repair implant capable of injection delivery
A conformable tissue implant is provided for use in repairing or augmenting a tissue defect or injury site. The tissue implant contains a tissue carrier matrix comprising a plurality of...
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7294352 |
Matrix protein composition for treating inflammation
Active enamel substances may be used for the preparation of a pharmaceutical or cosmetic composition for healing of a wound, improving healing of a wound, soft tissue regeneration or repair, or for...
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7291179 |
Bone graft substitute composition
Bone graft substitute compositions and methods of making the compositions are disclosed. In some embodiments, a method of making a composition includes contacting a mixing solution with a first...
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7241874 |
Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue
A method for purifying bone-derived osteogenic proteins including a demineralization process, a protein extraction process, a high molecular weight ultrafiltration process, a low molecular weight...
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7208179 |
Methods for treating disease and forming a supplemented fibrin matrix
This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one...
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7179492 |
Traditional chinese pharmaceutical formulation for treatment of paradentosis&comma process for preparation and use thereof
This invention involves a traditional Chinese medical preparation, its preparation and use. The present Chinese medicine that treats periodontitis is a pharmaceutically acceptable oral preparation...
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7132110 |
Tissue repair compositions and methods for their manufacture and use
An osteogenic composition is prepared by a process including the steps of subjecting demineralized bone to an extraction medium to produce an insoluble extraction product and a soluble extraction...
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7081240 |
Protein mixtures for wound healing
A protein mixture that is useful in the treatment of wounds, where the mixture is isolated from bone or is produced from recombinant proteins and may include two or more of BMP-2, BMP-3, BMP-4,...
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7033611 |
Matrix protein compositions for guided connective tissue growth
The present invention relates to the use of enamel matrix, enamel matrix derivatives and/or enamel matrix proteins as therapeutic and/or cosmetic agents. These substances are used for the...
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7022347 |
Restorative and grafting material for hard tissue defects prepared from animal teeth
The restorative and grafting material for reconstruction of hard tissue defects and the fabrication method of the same are provided. In particular, the restorative and grafting material of this...
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7005144 |
Antler composition and its manufacturing process
An antler composition and its manufacturing process are disclosed, the composition comprises an antler extract mixture and a matrix which comprises β-cyclodextrin, a higher ester compound, a...
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6979670 |
Matrix protein compositions for grafting
Enamel matrix, enamel matrix derivatives and/or enamel matrix proteins are used in the preparation of a pharmaceutical composition for promoting the take of a graft, e.g. in soft tissue such as...
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6844424 |
Method for obtaining avian biological products
This invention provides a method for separating and extracting biological products of avian origin. The method allows for the production of avian cartilages and of active ingredients which can be...
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6830763 |
Continuous acidification demineralization process for producing osteoinductive bone; and osteoinductive bone produced thereby
The invention is directed to a process for producing demineralized osteoinductive bone, and demineralized osteoinductive bone produced thereby. The process achieves demineralization of bone by...
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6787159 |
Process for the preparation of a cosmetic extract from marine ooze
The invention relates to a process for the preparation of extracts from marine ooze. To extract a larger proportion of the cosmetically and balneologically active ingredients from the ooze, the...
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6730323 |
Microclysmic gel for treatment of tissue trauma and burns
A therapeutic wound gel is provided which will enhance healing of the wound and reduce swelling and increase elasticity of the skin. Humatrix is bacteriostatic protectant with no bacteriocidal...
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6720009 |
Matrix protein compositions for treating infection
Active enamel substances may be used for the preparation of a pharmaceutical or cosmetic composition for healing of a wound, improving healing of a wound, soft tissue regeneration or repair, or for...
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6652887 |
Bone graft substitute composition
A composition includes calcium sulfate hemihydrate, an accelerant material, e.g., calcium sulfate dihydrate, a plasticizing material, a mixing solution, and demineralized bone matrix having a...
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6635285 |
Shark cartilage extract: process of making, methods of using, and compositions thereof
The present invention relates to cartilage extracts and to a method of producing the same. Shark cartilage extracts having anti-angiogenic, anti-tumor, anti-inflammatory and anti-collagenolytic...
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6627230 |
Method of preparing a bone product by removing cancellous bone matrix
A method and apparatus for preparing a bone product are provided. The method includes contacting an interior section of a cylindrical bone portion with a high pressure fluid medium such as at least...
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6627229 |
Antiviral agent and method of producing the same
An antiviral agent of an antiviral ability against various viruses and a method of producing the same are provided. A heat treatment is applied to a calcium-containing substance represented by...
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6576249 |
Bone putty and method
A method for the preparation of bone gel and bone putty which comprises producing a viscous supernatant by dissolving demineralized bone matrix in water or a solution comprising water and at least...
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6565884 |
Bone graft material incorporating demineralized bone matrix and lipids
A demineralized bone putty composition comprises: (1) demineralized bone matrix (DBM); and (2) a lipid fraction selected from the group consisting of lecithin and a mixture of lecithin and...
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6548080 |
Method for partially demineralized cortical bone constructs
The invention is directed toward a sterile bone structure for application to a bone defect site to promote new bone growth at the site comprising a partially demineralized cortical bone structure,...
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6534095 |
Pulsatile acidification wave demineralization process for producing osteoinductive bone; and osteoinductive bone produced thereby
The invention is directed to a process for producing demineralized osteoinductive bone, and demineralized osteoinductive bone produced thereby. The process achieves demineralization of bone by...
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6511958 |
Compositions for regeneration and repair of cartilage lesions
Disclosed is a cartilage repair product that induces both cell ingrowth into a bioresorbable material and cell differentiation into cartilage tissue. Such a product is useful for regenerating...
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6503539 |
Matrix protein compositions for wound healing
Active enamel substances may be used for the preparation of a pharmaceutical or cosmetic composition for healing of a wound, improving healing of a wound, soft tissue regeneration or repair, or for...
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6458763 |
Bone sialoprotein-based compositions for enhancing connective tissue repair
The present invention is directed to bioactive compositions that induce the repair of damaged or diseased connective tissues upon contact of the damaged or diseased tissues with the composition in...
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6444236 |
Compositon containing medicinal herbs and young antlers of cornu cervi
A composition is provided for use in health foods for promoting the circulation of blood, prepared from medicinal herbs, including Lycium chinense Miller, Agastache rugosa (Fischer et Meyer) O....
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6432918 |
Methods and compositions for optimization of oxygen transport by cell-free systems
Compositions, and methods of use thereof, for use as blood substitute products comprise aqueous mixtures of oxygen-carrying and non-oxygen carrying plasma expanders and methods for the use thereof....
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6417166 |
Thin mineralized collagen membrane and method of making same
A strong, thin flexible mineralized collagen membrane is disclosed that is useful for such medical applications as a barrier for guided tissue regeneration, periodontal defect repair, bone grafts...
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6387391 |
Bioresorbable polymeric clayey and sticky substance
This invention provides a claycy and sticky substance as a new biomaterial that cannot be found in the current medical field, which is bioresorbable, shows tackiness, plasticity and shape holding...
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6372257 |
Compositions and methods for forming and strengthening bone
Compositions are provided which stimulate bone growth. Also provided are methods for utilizing the compositions for filling in bone defects, promoting rapid fusion of bone fractures, grafts, and...
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6342252 |
Process for producing a bio-organic calcium composition and nutrient agent containing the same
A process of producting bio-organic calcium composition from animal bones comprises steps of preliminarily removing lipids from the bones by steaming/boiling; milling the bones to form a bone...
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6340477 |
Bone matrix composition and methods for making and using same
The invention is directed to a bone matrix composition for use in the repair and healing of osseous tissue. The composition can be used in load-bearing and non-load bearing applications, including...
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6300315 |
Mineralized collagen membrane and method of making same
A thin, strong, flexible mineralized collagen membrane is disclosed that is useful for such medical applications as a barrier for guided tissue regeneration, periodontal defect repair, bone grafts...
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6261586 |
Bone graft composites and spacers
A bone graft substitute including a composition of natural selectively deactivated bone material which has been processed to remove associated non-collagenous bone proteins, said bone material...
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6231879 |
Biocompatible devices with foam scaffolds
This invention is directed to methods of manufacturing implantable biocompatible cell encapsulation devices, wherein the cell encapsulation devices have a jacket made of a permeable, biocompatible...
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6099867 |
Nutraceutical antler powder and a method of producing same
A nutraceutical composition comprising water insoluble antler powder or water soluble antler powder or a combination of both. Also disclosed is a method of producing antler powder, either water...
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6093421 |
Maca and antler for augmenting testosterone levels
Testosterone levels in men are increased by the oral administration of powdered maca and antler.
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