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8142993 |
Method of preparing neutrophil-depleted platelet-rich plasma
Methods of producing neutrophil-depleted platelet-rich plasma by passing a blood, platelet or platelet-rich plasma fraction through a narrow, twisted and/or charged environment to remove...
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8137663 |
Oncolytic virus therapy
A method of treating a human subject with cancer is disclosed. A pharmaceutical composition is administered to the subject, the pharmaceutical composition comprising human leukocytes and a...
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8105632 |
Cell-derived microparticles as hemostatic agents for control of hemorrhage and treatment of bleeding disorders
Compositions comprising membrane-derived and synthetic microparticles that induce platelet aggregation and are useful for treating bleeding disorders, particularly those involving platelet...
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8088416 |
Process for obtaining high efficiency human albumin for use in detoxification therapy
A process for purifying and collecting albumin from plasma and plasma fractions involves diafiltration of an albumin-containing plasma fraction; stabilizing the resulting albumin fraction with...
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8084052 |
Chemical composition for controlling insects
The invention herein provides for an improved pesticide that includes at least one attractant, at least one plant growth stimulator and an insecticide. The pesticide eradicates fire ants and...
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7906149 |
Method for treating allergic dermatitis
A method for treating oleoresin induced allergic dermatitis by topically contacting an affected area with a therapeutically effective amount of one or more biopolymers for a sufficient amount of...
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7875182 |
Size-selective hemoperfusion polymeric adsorbents
Size-selective hemocompatible porous polymeric adsorbents are provided with a pore structure capable of excluding molecules larger than 50,000 Daltons, but with a pore system that allows good...
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7838039 |
Autologous fibrin sealant and method for making same
Provided are methods of applying biological compositions, that is, autologous bioadhesive sealant compositions containing one or more biological agents, to an individual, wherein all the blood...
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7837708 |
Accelerated healing with intraoperative combination of suture and autogenous blood components
A suture combined intraoperatively with autogenous blood components. At least one strand of suture is placed into a sterile container. Blood obtained from a patient is separated, using a...
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7837878 |
Method and system for colloid exchange therapy
The present invention relates to a method and system for using a hemofilter to treat IMRD, hepatic failure, exogenous intoxication and other conditions associated with toxins in a patient's blood....
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7811607 |
Autologous fibrin sealant and method for making the same
The present relates to an autologous bioadhesive sealant composition or fibrin glue prepared by a two-phase method, wherein all of the blood components for the bioadhesive sealant are derived from...
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7790039 |
Tangential flow filtration devices and methods for stem cell enrichment
The present invention provides methods for enriching a heterogenous mixture of bone marrow or blood constituents for stem cells by removal of non-stem cell constituents comprising separation of the...
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7744926 |
Use of a biologically active blood serum for the treatment of stroke
The present invention relates to the use of a pharmacologically active blood serum product producible by a method comprising electrostimulation of a non-human animal, withdrawal of blood from said...
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7708977 |
Method for diagnosis and treatment of vascular disease
A method for diagnosing decreased vascular function is disclosed. The method includes assaying the number of endothelial progenitor cells. A method for detecting increased cardiovascular risk is...
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7700132 |
Isolated material having an anti-organotrophic effect
An endogenous mammalian material has been found which has the biological effect of causing a reduction in the mass of mammalian organs including the heart and prostate. The material has...
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7700733 |
Factor VII or VIIa polypeptide variants
The present invention relates to novel polypeptide variants of factor VII (FVII) or factor VIIa (FVIIa) polypeptides, where said variants comprise an amino acid substitution in position 10 and 32...
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7611831 |
Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition containing cells while substantially maintaining a desired biological...
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7521417 |
Method and apparatus for preparing an acellular red blood cell substitute
A process is disclosed for the preparation of an essentially tetramer-free, substantially stroma-free, polymerized, pyridoxylated hemoglobin. Also disclosed is an essentially tetramer-free,...
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7507418 |
Adenovirus status as a predictor of body composition change, disease status, and treatment outcomes
Infection with obesifying adenoviruses in animals and humans may be used to predict changes in body weight and disease status. More particularly, infection with certain adenoviruses, such as...
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7498156 |
Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
This invention is directed towards a method of using visible light at wavelengths of at least 500 nm and above in combination with a sensitizer having a flavin moiety to reduce any pathogens that...
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7452529 |
Treatment of muscular dystrophy with cord blood cells
The invention features methods for treating a patient suffering from muscular dystrophy by administration of umbilical cord blood cells, e.g., by IV infusion.
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7374765 |
Methods and compositions for diagnosis and treatment of iron misregulation diseases
Methods and compositions are provided for the diagnosis and treatment of iron misregulation diseases, including HFE polypeptides, agonists, and antagonists, and transferrin receptor agonists and...
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7351422 |
Hemostatic soluble cellulose fibers containing coagulating protein for treating wound and process for producing the same
Proposed is a novel soluble trauma-healing and hemostatic cellulose fiber capable of absorbing and readily dissolving hemorrhaging trauma loci when applied thereto and of promoting the hemostatic...
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7348411 |
Process for manufacturing fibrin membranes and fibrin membranes obtained according to this process
A process for manufacturing a fibrin membrane from blood plasma that was partially depleted and subjected to coagulation by adding a solution of a physiological coagulating agent, leaving the...
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7291592 |
Method for treating patients with massive blood loss
Methods for treating a mammal suffering from massive blood loss comprising administering to the mammal a polymerized hemoglobin solution.
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7255880 |
Treatment of endothelin-related disorders
Endothelin-related disorders in mammals can be alleviated by administration to such patients of one or more aliquots of mammalian blood subjected to two or more stressors selected from temperature...
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7223391 |
Method for treating mammals with modified mammalian blood
An improved method for treating or preventing a pathological condition in a mammalian subject in which modified mammalian blood is administered to the subject. The method comprises administering to...
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7208179 |
Methods for treating disease and forming a supplemented fibrin matrix
This invention provides supplemented and unsupplemented tissue sealants as well as methods for their production and use thereof. Disclosed are tissue sealants supplemented with at least one...
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7201918 |
Compositions, systems and methods for treatment of defects in blood vessels
Methods and systems are provided for treating a vascular structure having a defect, for example, a cerebral artery having a weakened wall that has formed an aneurysm. The methods include...
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7182744 |
Method and apparatus for aneurismal treatment
An irritant or polymer is dispensed to the inner surface area of an aneurysm to exert a contractile force on the inner surface area of the aneurysm, thereby shrinking the aneurysm. As a result, the...
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7179447 |
Type I interferon-producing cells and uses thereof
The present invention provides compositions for the treatment, inhibition or prevention of diseases or disorders, including cancer, immune diseases or disorders, and infectious diseases, comprising...
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7135553 |
Polymerized hemoglobin solutions having reduced amounts of tetramer and method for preparing
A substantially tetramer free hemoglobin solution and a method for producing a substantially tetramer free hemoglobin solution. The method includes polymerizing a solution of hemoglobin, treating...
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7122208 |
Compositions containing apoptotic entities
Disclosed are methods for treating and preventing neurological disorders which have a significant inflammatory component. The methods of the present invention involve extracting blood from a...
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7105312 |
Ca2+/calmodulin-dependent protein kinase IV
The present invention relates to Ca2+/calmodulin-dependent protein kinase IV (CaMKIV) and, in particular, to methods of screening compounds for their ability to act as CaMKIV agonists or...
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7101846 |
Methods and compositions for optimization of oxygen transport by cell-free systems
Compositions, and methods of use thereof, for use as blood substitute products comprise aqueous mixtures of oxygen-carrying and non-oxygen carrying plasma expanders and methods for the use thereof....
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7094378 |
Method and apparatus for inactivation of biological contaminants using photosensitizers
Methods and apparatuses for treating fluids to inactivate microorganisms which may be present therein, said fluid containing one or more components selected from the group consisting of protein,...
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7067139 |
Method for treating autoimmune diseases
A method of treating patients having rheumatoid arthritis by administering Product R, a peptide-nucleic acid preparation, is disclosed.
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7045148 |
Method of collecting placental stem cells
A method of collecting embryonic-like stem cells from a placenta which has been treated to remove residual cord blood by perfusing the drained placenta with an anticoagulant solution to flush out...
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7037642 |
Removing compounds from blood products with porous particles immobilized in a matrix
Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition containing cells while substantially maintaining a desired biological...
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7015198 |
Materials for soft tissue augmentation and methods of making and using same
Materials for soft tissue augmentation in mammals are prepared by cross-linking blood plasma proteins, preferably with a zero-length cross-linking agent. The cross-linked blood plasma proteins can...
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7001715 |
Purification of red blood cells by separation and diafiltration
Red blood cells are purified by separating whole blood, such as by centrifugation, to form a red blood cell fraction and a liquid fraction. The whole blood can be defibrinated or treated to prevent...
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6986984 |
Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier
Red blood cells are purified by defibrinating whole blood and then filtering the defibrinated whole blood, whereby at least a portion of a plasma component is separated from the red blood cells to...
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6979307 |
Systems and methods for preparing autologous fibrin glue
The invention provides a system for preparing an autologous solid-fibrin web suitable for regenerating tissue in a living organism. The system includes a sealed primary container containing a...
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6951713 |
Absorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition, while substantially maintaining a desired biological activity of the...
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6942879 |
Bioartificial filtration device for filtering blood to mimic kidney function
A novel cell seeded hollow fiber bioreactor is described as a potential bioartificial kidney. Endothelial cells along with pericyte, vascular smooth muscle, and/or mesangial cells or any...
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6914127 |
Acellular red blood cell substitute
An acellular red blood cell substitute which comprises an essentially tetramer-free, substantially stroma-free, cross-linked, polymerized, pyridoxylated hemoglobin and a nontoxic, pharmaceutically...
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6899863 |
Method for preparing membrane vesicles
This invention relates to a method of preparing membrane vesicles from a biological sample, characterised in that it comprises at least one anion exchange and/or gel permeation chromatography...
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6830762 |
Autologous fibrin sealant and method for making the same
The present relates to an autologous bioadhesive sealant composition or fibrin glue prepared by a two-phase method, wherein all of the blood components for the bioadhesive sealant are derived from...
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6800300 |
Method for treating autoimmune and alloimmune diseases
Disclosed is a method for treating a mammalian subject suffering from an autoimmune or alloimmune disease by administering to the subject a drug treatment which results in at least partial...
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6783775 |
Serum-derived factor inducing cell differentiation and medical uses thereof
The present invention relates to a biologically active serum-derived composition of matter (SDF), having a low molecular weight, being electrically charged at acidic pH and having absorption at 280...
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