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8168225 |
Continuous multi-microencapsulation process for improving the stability and storage life of biologically active ingredients
The invention relates to microcapsules, and a continuous micro-encapsulation water-in-oil-in-water microencapsulation process through in situ and interfacial polymerization of the emulsion. The...
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8168576 |
Volume giving cleansing composition
The present invention is related to an aqueous cleansing composition especially for keratin fibers such as human hair with excellent volume enhancing effect. First object of the present invention...
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8142814 |
Method and apparatus for supercritical fluid assisted particle production
The present invention provides an apparatus and methods of producing particles that include a polymer, a wax and/or lipid and, optionally, a biologically active substance. In accordance with the...
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8057823 |
Lipid nanocapsules, preparation process and use as medicine
The invention concerns nanocapsules, in particular with an average size less than 50 nm, consisting of an essentially lipid core liquid or semiliquid at room temperature, coated with an essentially...
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8039015 |
Microencapsulation product and process
Microcapsules possessing Lewis acid-Lewis base salt walls incorporate water-immiscible materials, such as N,N-diethyl-m-toluamide (DEET), as a core component. Such microcapsules, or similar...
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7999005 |
Growth stimulant compositions
An improved weight and growth stimulant for domesticated animals such as cattle, pigs and sheep is comprised of an anabolic agent that is subcutaneously administered in the form of a dual release...
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7981911 |
Pharmaceutical formulations
Improved pharmaceutical compositions are provided comprising one or more solubilized HIV protease inhibiting compounds having improved solubility properties in a medium and/or long chain fatty...
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7927628 |
Sustained release preparations and process for producing the same
The present invention provides sustained-release preparations from which a pharmacologically active substance can be released over a long time and a process for producing the same. Such a...
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7914801 |
Metabolizable oil emulsion adjuvants and vaccines for enhancing immuno-properties of antibodies and their subpopulations
Water-in-oil priming emulsion vaccines increase the titers and/or avidity indexes of antibodies following a second dose of a commercial or experimental vaccine resulting in increased protection for...
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7906144 |
Solubilizing aids in powder form for solid pharmaceutical presentation forms
The invention relates to excipients in powder form for use in solid pharmaceutical presentations, comprising a pharmaceutically acceptable polymer and a liquid or semisolid solubilizing...
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7871598 |
Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
Microparticle compositions comprising metal ion-lipid complexes for drug delivery are described including methods of making the microparticle compositions and methods of treating certain conditions...
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RE41884 |
Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions
Disclosed are methods of intravenous administration of nanoparticulate drug formulations to a mammal to avoid adverse hemodynamic effects: by reducing the rate and concentration of the...
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7820202 |
Extended release particle dispersion
The invention relates to extended release compositions that can be advantageously used as drug products, plant protection agents, in foods or other products. The invention especially relates to...
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7807200 |
Formulations for spray-drying large porous particles
Particles having a tap density less than about 0.4 g/cm3 are formed by spray drying from a colloidal solution including a carboxylic acid or salt thereof, a phospholipid, a divalent salt and a...
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7785625 |
Lipophilic-coated microparticle containing a protein drug and formulation comprising same
A solid lipophilic microparticle having an average particle size ranging from 0.1 to 200 μm, comprising a lipophilic substance, hyaluronic acid or an inorganic salt thereof and an active ...
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7758884 |
Formulation for increasing the deposition of dietary carotenoids in eggs
The absorption and deposition of carotenoids added to poultry diets into the yolk of eggs produced by the poultry is improved by adding a carotenoid formulation comprising a carotenoid, a vegetable...
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7754242 |
Inhalable sustained therapeutic formulations
The present invention is based, in part, on the unexpected discovery that particles for pulmonary delivery of a therapeutic, prophylactic or diagnostic agent that comprise a phospholipid and a...
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7737108 |
Enhanced transport using membrane disruptive agents
Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are...
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7695727 |
Botanical butter stick lip balm
A stick lip balm with efficacious amounts of natural moisturizer and organoleptic/sensory attributes of lip feel associated with moisturizers and emollients is provided. The lip balm of the...
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7670627 |
pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
The present invention relates to a novel pH triggered, targeted controlled release system. The controlled delivery system of the present invention is substantially a free-flowing powder formed of...
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7582312 |
Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
Methods of producing lung surfactant formulations through solvent dissolution and lyophilization are described as well as surfactant formulations derived therefrom. Methods of treating respiratory...
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7537787 |
Method for modulating glutamate and/or aspartate release in a central nervous system locus
Methods and compositions are disclosed for providing prolonged-release of therapeutic agents by way of in situ stereotaxic implantation in specific loci, including pathways, to treat know...
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7534449 |
Targeted and high density drug loaded polymeric materials
Polymeric delivery devices have been developed which combine high loading/high density of molecules to be delivered with the option of targeting. As used herein, “high density” refers to mic...
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7479490 |
Pellet for a presurrized pipeline
A system of equipment allowing addition of solid materials to a pressurized pipeline wherein said solid material is conveyed in such a way as to be readily dissolved by the liquid in said pipeline....
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7473433 |
Pulmonary delivery of polyene antifungal agents
The present invention provides spray-dried polyene compositions for oral inhalation to the lung. The polyene antifungal compositions demonstrate superior aerosol properties, do not exhibit...
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7442385 |
Chemoembolisation
A composition for chemoembolotherapy of solid tumours comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer...
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7442388 |
Phospholipid-based powders for drug delivery
Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature...
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7407667 |
Pesticidal preparations comprising copolymers
The present invention relates to aqueous concentrates and solid formulations of pesticide preparations comprising copolymers which may be obtained by copolymerization of a) glycerol, b) at least...
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7404966 |
Transfer-resistant makeup removing compositions
The invention relates to a cleansing composition suitable for topical application to human skin, more particularly to an oil-based cleansing composition containing a silicone elastomer gelling...
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7399488 |
Abuse-deterrent pharmaceutical compositions of opiods and other drugs
An abuse-deterrent pharmaceutical composition has been developed to reduce the likelihood of improper administration of drugs, especially drugs such as opiods. In the preferred embodiment, a drug...
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7291348 |
Compositions and methods for biodegradable microspheres as carriers of bioactive substances
A cost-effective, scalable technique for producing microspheres loaded with biologically active solid proteins is provided. The microspheres degrade over time and release biologically active VEGF,...
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7282221 |
Antiviral product, use and formulation thereof
An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve...
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7279182 |
Formulation for spray-drying large porous particles
Particles having a tap density less than about 0.4 g/cm3 are formed by spray drying from a colloidal solution including a carboxylic acid or salt thereof, a phospholipid, a divalent salt and a...
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7276251 |
Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid
A sustained-release drug composition consisting essentially of microparticles of hyaluronic acid having a high molecular weight or an inorganic salt thereof and a protein or peptide drug encased in...
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7252840 |
Use of simple amino acids to form porous particles
Particles having a tap density of less than 0.4 g/cm3 include a hydrophobic amino acid or salt thereof and a therapeutic, prophylactic or diagnostic agent or any combination thereof. Preferred...
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7220433 |
Compositions for parenteral administration and sustained-release of therapeutic agents
The present invention is directed to parenterally-administrable microparticles for providing sustained-release of a therapeutic agent in the body, where the microparticles include a polymeric core...
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7217427 |
Polymersomes and related encapsulating membranes
The present invention provides biocompatible vesicles comprising semi-permeable, thin-walled encapsulating membranes which are formed in an aqueous solution, and which comprise one or more...
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7205343 |
Stabilized bioactive preparations and method of use
Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that...
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7195780 |
Nanoparticle delivery system
The invention relates to the nanotubes of various sizes and composed of a wide variety of materials, or combination of materials. The invention also describes the use of such nanotubes for the...
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7179490 |
Sustained release ionic conjugate
A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing biodegradable polymer and a free amino group-containing drug which are ionically bonded...
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7176171 |
Low-viscosity opacifiers without anionic surface-active agents
An emulsifier mixture for use in a wax-based opacifier composition is comprised of: (a) an alkyl and/or alkenyl oligoglycoside; (b) a fatty acid partial glyceride and optionally (c) at least one...
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7163697 |
Biodegradable polymer compositions, compositions and uses related thereto
The present application is directed to biodegradable polymers, compositions, including microspheres and nanospheres, formed of such polymers, and methods of using such polymers and compositions. In...
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7160557 |
Matrices formed of polymer and hydrophobic compounds for use in drug delivery
A lipid or other hydrophobic or amphiphilic compound (collectively referred to herein as “hydrophobic compounds”) is integrated into a polymeric matrix for drug delivery to alter drug release kin...
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7141593 |
Pharmaceutical formulations
Improved pharmaceutical compositions are provided comprising one or more solubilized HIV protease inhibiting compounds having improved solubility properties in a medium and/or long chain fatty...
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7108859 |
Antineoplastic product, use and formulation thereof
An antineoplastic product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antineoplastic product being reached in less than about...
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7105174 |
Multiple-delayed release anti-neoplastic product, use and formulation thereof
An anti-neoplastic product is comprised of at least three delayed release dosages forms, each of which has a different release profile, with the Cmax for the anti-neoplastic product being reached...
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7101568 |
Methods and compositions for treating solid tumors
A biodegradable polymer composition comprising: (a) a poly(phosphoester) biodegradable polymer and(b) at least one antineoplastic agent in an amount effective to inhibit the growth of a solid...
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7097849 |
Injectable aqueous dispersions of propofol
Irritation upon injection of a formulation containing propofol is reduced or substantially eliminated by administering a stable, sterile, and antimicrobial aqueous dispersion comprising a...
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7090831 |
Pharmaceutical aerosol formulation
The present invention relates to novel pharmaceutical aerosol formulations comprising: (A) salmeterol xinafoate in the form of particles coated by spray-drying with at least one surfactant in the...
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7074417 |
Multiple-delayed release anti-viral product, use and formulation thereof
An anti-viral product is comprised of at least three delayed release dosage forms, each of which has a different release profile, with the Cmax for the anti-viral product being reached in less than...
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