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7473433 |
Pulmonary delivery of polyene antifungal agents
The present invention provides spray-dried polyene compositions for oral inhalation to the lung. The polyene antifungal compositions demonstrate superior aerosol properties, do not exhibit...
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7241813 |
End-capped polymers and compositions containing such compounds
End-capped polymers, methods for making those end-capped polymers and compositions containing those end-capped polymers are disclosed. One of the disclosed end-capped copolymers has the formula:
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7208480 |
Polysaccharide based gel
A fluid gel obtainable by a process which comprises subjecting a solution comprising a mixture of xanthan and one or more non-gelling polysaccharides selected from galactomannans or glucomannans in...
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7182957 |
Polymer blends that swell in an acidic environment and deswell in a basic environment
A polymer blend is prepared by dissolving chitosan and a second polymer in an acidic aqueous solution to form an aqueous polymer blend, dehydrating said aqueous polymer blend, and recovering said...
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7172766 |
Controlled release insufflation carrier for medicaments
Controlled release powder insufflation formulations are disclosed. The powder formulation includes cohesive composites of particles containing a medicament and a controlled release carrier which...
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7115586 |
Non-inclusion cyclodextrin complexes
The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization...
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7105176 |
Production of solid preparations of water-soluble, sparingly water-soluble or water-insoluble active compounds
A process is described for producing solid preparations of at least one water-soluble, sparingly water-soluble or water-insoluble active compound suitable for the food and animal feed sectors or...
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7084132 |
Artemisinins with improved stability and bioavailability for therapeutic drug development and application
A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation...
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7081450 |
Water soluble nanoparticles of hydrophilic and hydrophobic active materials and an apparatus and method for their production
This invention provides a soluble nano-sized particles formed of a core (water-insoluble lipophilic compound or hydrophilic compound) and an amphiphilic polymer and which demonstrated improved...
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7025991 |
Drug targeting system, method of its preparation and its use
A composition and method of fabrication are presented with which nanoparticles may be used as a tool to deliver drugs to a specific target within or on a mammalian body. Specifically, by using...
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7022313 |
Hydrogel particle formulation
New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle...
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7008627 |
Use of complexes for the preparation of compositions for the treatment of sensitive skin, preparation process and hypoallergenic compositions
This invention relates to new dermocosmetic and pharmaceutical compositions which are useful for improving and treating hyperreactive skin conditions and more generally allergic-type reactions...
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6994873 |
Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration
This invention refers to:
multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional...
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6982091 |
Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy
Devices, methods, and compositions for cancer therapy by administration of chemotherapeutic agents and/or inhibitors of membrane efflux systems to the vagina for topical and systemic tumor targets.
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6939530 |
Preparation of further diagnostic agents
Microspheres are prepared by a process comprising (i) spray-drying a solution or dispersion of a wall-forming material in order to obtain intermediate microspheres and (ii) reducing the...
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6936277 |
Pharmaceutical excipient having improved compressibility
A method of preparing an excipient composition includes forming an aqueous slurry containing a mixture of microcrystalline cellulose in the form of a wet cake and a surfactant, said surfactant...
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6884885 |
Production of cyclodextrin complexes
The process entails increasing the concentration of cyclodextrin to 15% (w/w) and above to form complexes through a precipitation process in order to increase the yield of complexes, increase the...
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6884756 |
Water-dispersible pellets
A water-dispersible particle for delivery of nitrogen to a plant is disclosed. The water-dispersible particle also delivers an active ingredient such as a plant hormone to a desirable plant or a...
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6878693 |
Hydrophilic complexes of lipophilic materials and an apparatus and method for their production
This invention provides a soluble inclusion complex formed of a water-insoluble lipophilic compound and an amphiphilic polymer and which demonstrated improved solubility and stability. The...
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6852709 |
Biologically useful polyphosphates
The present invention provides biodegradable polymers, polymer compositions, particles composed thereof and methods of using same for the controlled release of a biologically active substance to a...
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6828334 |
Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition
The present invention relates to pharmaceutical compositions containing fenofibrate in the form of an inclusion complex with cyclodextrin, having high dissolution profile and in vivo enhanced...
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6793938 |
Biodegradable compositions for the controlled release of encapsulated substances
Pharmaceutical compositions that enable the release of a physiologically active substance over a prolonged period of time following administration to a patient are described. The pharmaceutical...
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6793937 |
Method of delivering active material within hydrogel microbeads
A method of delivering active material using microbeads comprising droplets of active material entrained in a hydrophilic matrix. Compositions comprising the microbeads may be sprayable. The...
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6774151 |
Method of producing an absorbent foam material
A method of producing a porous, liquid absorbent, open-cell polymeric foam material having properties which makes it suitable for use as an absorbent structure in absorbent articles such as...
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6761910 |
Pharmaceutical composition for the treatment of acute disorders
A pharmaceutical composition for the treatment of acute disorders is described. The composition comprises an essentially water-free, ordered mixture of at least one pharmaceutically active agent in...
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6759059 |
Fentanyl composition for the treatment of acute pain
A pharmaceutical composition for the treatment of acute pain by sublingual administration is described. The composition comprises an essentially water-free, ordered mixture of fentanyl or a...
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6726934 |
Micro-particulate and nano-particulate polymeric delivery system
The present invention provides a method of making particles useful in drug delivery, comprising the steps of: contacting polyanionic polymers with cations in a stirred reactor so that polyanions...
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6713088 |
Low viscosity filler composition of boron nitride particles of spherical geometry and process
A low viscosity filler boron nitride agglomerate particles having a generally spherical shape bound together by an organic binder and to a process for producing a BN powder composition of...
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6706263 |
Composition for alleviating symptoms of uremia in patients
Microencapsulated and/or enteric coated compositions containing a mixture of sorbents with specific adsorption affinities for uremic toxins including ammonia, urea, creatinine, phenols, indoles,...
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6689755 |
Method of stabilizing biologically active substances
The present invention relates to a rapid and readily reproducible process for stabilizing biologically active substances by combining the biologically active substance witha a stabilizingmixture...
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6689388 |
Microencapsulated delivery system for high viscosity fluids
Disclosed is a process for producing powders from high viscosity fluids including mixing a mixture comprising a high viscosity fluid and at least one absorbing agent until a dry dispersion is...
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6689345 |
Care or make-up composition containing fibers and a hydrophilic polyoganosiloxane
A care or make-up composition for keratin substances such as the skin, the lips or superficial body growths, this composition containing fibers and particles of an at least partially crosslinked...
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6680284 |
Method for producing powdery particle-reduced formulations with the aid of compressed gases
For the preparation of pulverulent particle-reduced formulations with the aid of compressed gases, the solid compound to be formulated, a poorly soluble and usually bioactive active compound, is...
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6669963 |
Stable particle in liquid formulations
A stable particle in liquid formulation comprising a discontinuous phase of microparticles is suspended in a continuous phase which is a non-aqueous liquid, preferably biocompatible in which the...
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6656508 |
Sustained-release alginate gels
The present invention relates to sustained-release formulations using alginate gel beads and methods thereof.
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6638537 |
Microemulsion and micelle systems for solubilizing drugs
A microemulsion delivery system for water insoluble or sparingly water soluble drugs that comprises a long polymer chain surfactant component and a short fatty acid surfactant component, with the...
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6623762 |
Composition and method for controlled release injections
The present invention is a pharmaceutical composition and method for controlling the release of a drug or vaccine to a patient where a slow, controlled release of drug or antigen occurs over a...
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6608050 |
Lyophilizate of lipid complex of water insoluble porphyrins
The present invention relates to a pharmaceutically acceptable dosage form of water insoluble porphyrins, particularly metal containing porphyrins such as tin porphyrin, which can be complexed with...
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6562372 |
Tocotrienol-containing powder, a process for preparing it and a tablet comprising compressed said powder into a tablet form
A tocotrienol-containing powder prepared by a process wherein an oil containing a tocotrienol is treated with a lecithin, a cellulose and an emulsifying agent in water to form an emulsion, a powder...
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6551619 |
Pharmaceutical cyclosporin formulation with improved biopharmaceutical properties, improved physical quality and greater stability, and method for producing said formulation
The invention relates to solid, particulate lipid-based excipients which are loaded with cyclosporine. Said excipients have improved biopharmaceutical properties for cyclosporines in vivo, are of a...
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6531155 |
Granulates for cosmetic and pharmaceutical preparations
Granular materials are obtainable by pressing mixtures of at least one pulverulent, rheology-modifying, carboxyl-containing polymer as main component and at least one oil-soluble component.
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6511650 |
Preparing porous hydrogel products
This invention is directed to a new approach to form porous hydrogel materials by first creating gas pockets in the gel and then removing this gas. The removal of the gas creates a porous material,...
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6506406 |
Soft capsule containing mastic oil therein
A soft capsule containing oil produced by dissolving mastic in oils and fats. The capsule may further contain amphipathic substance, chitin or chitosan. The capsule serves to remove and inhibit...
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6500463 |
Encapsulation of sensitive components into a matrix to obtain discrete shelf-stable particles
A solid active, sensitive encapsulant and/or a liquid encapsulant component which contains an active, sensitive encapsulant, is admixed with at least one plasticizable matrix material, a matrix...
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6497891 |
Make-up compositions
Cosmetic compositions comprising, in a cosmetically acceptable medium, at least one film-forming polymer and at least one water-superabsorbent polymer in the form of water-swelled particles, the...
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6495521 |
Combination therapy method for treating chronic hepatitis B
The present invention is aimed at augmenting the success rate of using thymosin in treatment of chronic hepatitis B, by employing a combination therapy using thymosin with antiviral agents which...
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6491953 |
Controlled release compositions and method
A controlled release composition comprising an adsorbent polymer, an active agent, and a release retardant is disclosed. The composition has an improved ability to release the active agent over an...
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6485738 |
Delivery system for enhanced bioavailability of nutrients and supplements
A gel delivery system for promoting bioavailability and uptake of vitamins, minerals and other nutritional supplements comprises a gel base, preferably including agar, water and a bioavailablity...
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6462093 |
Method for converting sparingly water-soluble medical substance to amorphous state
A process for producing a solid dispersion of a sparingly water-soluble medical substance which comprises subjecting the sparingly water-soluble medical substance, an amorphous state-inducing agent...
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6440462 |
Agglomerates of β-lactam antibiotics and processess for making agglomerates
Agglomerates of β-lactam antibiotics, such as penicilllin V potassium, amoxicillin trihydrate, cephalexin monohydrate, which are suitable for direct tablet formation.
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