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7615547 Granulates containing liposoluble substances and a process for the preparation thereof  
A process is described for the preparation of granulates that contain liposoluble and hydrophobic substances, preferably steroidal substances, and that exhibit rapid and excellent...
7611709 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives  
Disclosed are applications of oligosaccharides/oligosaccharide mixtures for the production and stabilization of pharmaceutical compositions, chiefly powders, that contain antibodies or antibody...
7601872 Transfection reagents  
Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the group consisting...
7601337 Delivery of antipsychotics through an inhalation route  
The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a...
7591999 Powdery preparation for nasal administration  
According to the present invention, a powdery preparation for nasal administration comprising a physiologically active substance, a non-water-absorbing and hardly water-soluble powder(s) and one or...
7585493 Thin-film drug delivery article and method of use  
An article for use in an aerosol device, for producing an aerosol of a drug composition is disclosed. The article includes a heat-conductive substrate having a surface with a selected surface area,...
7582312 Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof  
Methods of producing lung surfactant formulations through solvent dissolution and lyophilization are described as well as surfactant formulations derived therefrom. Methods of treating respiratory...
7582284 Particulate materials  
The present invention relates to active substances in particulate form, to methods for preparing them, to formulations containing them and to uses of such substances and formulations. A preferred...
7575763 Membrane scaffold proteins and tethered membrane proteins  
Membrane proteins are difficult to express in recombinant form, purify, and characterize, at least in part due to their hydrophobic or partially hydrophobic properties. Membrane scaffold proteins...
7556798 Highly efficient delivery of a large therapeutic mass aerosol  
A method for delivering an agent to the pulmonary system, in a single, breath-activated step or a single breath, comprises administering from a receptacle enclosing a mass of particles, to a...
7550443 Process and systems for biocompatible surfaces  
The invention provides methods and compositions for providing biocompatible surfaces to medical articles. In particular the invention provides biocompatible coatings with heparin activity that are...
RE40786 Vaccines against intracellular pathogens using antigens encapsulated within biodegradable-biocompatible microspheres  
This invention relates to parenteral and mucosal vaccines against diseases caused by intercellular pathogens using antigens encapsulated within a biodegradable-biocompatible microspheres(matrix).
7547446 Dry hemostatic compositions and methods for their preparation  
Dry cross-linked gelatin compositions are prepared that rapidly re-hydrate to produce gelatin hydrogels suitable as hemostatic sealants. Gelatin is cross-linked in the presence of certain...
7544374 Lipidated glycosaminoglycan particles and their use in drug and gene delivery for diagnosis and therapy  
Lipidated glycosaminoglycan particles are prepared by reacting a glycosaminoglycan with at least one lipid to cross-link the carboxylic acid groups in the glycosaiminoglycan with a primary amine in...
7524484 Delivery of diphenhydramine through an inhalation route  
The present invention relates to the delivery of diphenhydramine through an inhalation route. In a composition aspect of the present invention, a composition of a diphenhydramine condensation...
7521069 Methods and compositions for pulmonary delivery of insulin  
Systemic delivery of insulin to a mammalian host is accomplished by inhalation of a dry powder of insulin. It has been found that dry insulin powders are rapidly absorbed through the alveolar...
7517851 Chlamydia oligosaccharides  
Oligosaccharides specific for Chlamydia mediate attachment of the organism to host cells.
7510702 Delivery of nonsteroidal antiinflammatory drugs through an inhalation route  
The present invention relates to the delivery of nonsteroidal antiinflammatory drugs (NSAIDs) through an inhalation route. Specifically, it relates to aerosols containing NSAIDs that are used in...
7507398 Delivery of physiologically active compounds through an inhalation route  
The present invention relates to the delivery of physiologically active compounds through an inhalation route. Specifically, it relates to aerosols containing physiologically active compounds that...
7498019 Delivery of compounds for the treatment of headache through an inhalation route  
The present invention relates to the delivery of migraine headache drugs through an inhalation route. Specifically, it relates to aerosols containing migraine headache drugs that are used in...
7491047 Delivery of antihistamines through an inhalation route  
The present invention relates to the delivery of antihistamines through an inhalation route. Specifically, it relates to aerosols containing antihistamines that are used in inhalation therapy. In a...
7488469 Delivery of caffeine through an inhalation route  
The present invention relates to the delivery of caffeine through an inhalation route. Specifically, it relates to aerosols containing caffeine that are used in inhalation therapy. In a composition...
7482024 Compositions comprising an active agent  
The present invention provides a highly dispersible formulation comprising an active agent and a dipeptide or tripeptide comprising at least two leucyl residues. The composition of the invention...
7482020 Process for making an adjuvanted vaccine comprising host albumin  
A process for making an adjuvanted vaccine comprising host albumin. The process comprises mixing host serum or host serum with an antigen, and then mixing the resulting mixture with an adjuvant.
7470817 Transfection reagents  
Disclosed are compounds capable of facilitating transport of biologically active agents or substances into cells having the general structure: wherein Q is selected from the group consisting...
7470421 Delivery of diazepam through an inhalation route  
The present invention relates to the delivery of compounds for the treatment of anxiety disorders and symptoms of such disorders through an inhalation route. Specifically, it relates to aerosols...
7468179 Delivery of opioids through an inhalation route  
The present invention relates to the delivery of opioids through an inhalation route. Specifically, it relates to aerosols containing opioids that are used in inhalation therapy. In a method aspect...
7465436 Delivery of compounds for the treatment of Parkinson's through an inhalation route  
The present invention relates to the delivery of antiparkinsons drugs through an inhalation route. In a method aspect of the present invention, an antiparkinsons drug is administered to a patient...
7465435 Delivery of beta-blockers through an inhalation route  
The present invention relates to aerosols containing of atenolol, pindolol, esmolol, propranolol, or metoprolol that are used in inhalation therapy. In a method aspect of the present invention, of...
7462366 Drug delivery particle  
A drug delivery particle including a reservoir region having primarily large pores and a metering region. The particle can be highly spherical.
7449198 Stable salts of O-acetylsalicylic acid with basic amino acids  
The present invention relates to stable salts of O-acetylsalicylic acid with basic amino acids, a process for their preparation and their use as medicaments.
7449174 Delivery of analgesics through an inhalation route  
The present invention relates to the delivery of analgesics through an inhalation route. Specifically, it relates to aerosols containing acetaminophen, orphenadrine or tramadol that are used in...
7449172 Delivery of antiemetics through an inhalation route  
The present invention relates to the delivery of antiemetics through an inhalation route. Specifically, it relates to aerosols containing antiemetics that are used in inhalation therapy. In a...
7445768 Delivery of sedative-hypnotics through an inhalation route  
The present invention relates to the delivery of sedative-hypnotics through an inhalation route. Specifically, it relates to aerosols containing sedative-hypnotics that are used in inhalation...
7442368 Delivery of stimulants through an inhalation route  
The present invention relates to the delivery of stimulants through an inhalation route. Specifically, it relates to aerosols containing stimulants that are used in inhalation therapy. In a method...
7390503 Ondansetron orally disintegrating tablets  
An ondansetron solid orally disintegrating dosage form for oral administration having at least one first water-dispersible component or water-insoluble cellulose derivative, a component having a...
7387796 Stable compositions of S-adenosyl-l-methionine with dextran  
Stable compositions of S-adenosyl-1-methionine with dextran are described. The compositions according to the invention are stable over time and are valuable for use as active constituents in...
7378110 High pressure spray-dry of bioactive materials  
This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive...
7375064 Functionalized polymeric surfactants based upon alkyl polyglycosides  
The invention relates to a series of multifunctional polyglycosides derivatives that are made by the polymerized by the reaction of polyoxyalkylene containing crosslinking reagent and...
7371738 Method of transdermal drug delivery using hyaluronic acid nanoparticles  
The present invention relates to the development of a hyaluronic acid and hyaluronic acid hybrid nanoparticle systems for the administration of active molecules, peptides, DNA and/or other...
7364754 Ceramic based nanoparticles for entrapping therapeutic agents for photodynamic therapy and method of using same  
The present invention provides methods and compositions for photodynamic therapy. The composition comprises ceramic nanoparticles in which a photosensitive drug/dye is entrapped. The ceramic...
7358284 Particulate acellular tissue matrix  
A method of processing an acellular tissue matrix to give a particulate acellular tissue matrix includes: cutting sheets of dry acellular tissue matrix into strips; cryofracturing the dry acellular...
7322825 Method of treating periodontal disease using periodontal regeneration composition  
A periodontal structure regeneration composition for treatment of periodontal disease is a mixture of particles of a bone growth material and free collagen. The periodontal regeneration composition...
7303765 Ultrafine-L-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same  
L-carnitine which has a particle size such that it substantially passes through a 100 USBS mesh sieve exhibits an increased bioavailability, a decreased hygroscopicity, and may be conveniently...
7294344 Sustained-release preparation for AII antagonist, production and use thereof  
The present invention is to provide a sustained-release preparation which comprises a compound having angiotensin II antagonistic activity, its pro-drug or their salt, and a biodegradable polymer,...
7291598 Nanoparticles for protein drug delivery  
The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for...
7276251 Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid  
A sustained-release drug composition consisting essentially of microparticles of hyaluronic acid having a high molecular weight or an inorganic salt thereof and a protein or peptide drug encased in...
7258873 Preservation of bioactive materials by spray drying  
This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of...
7238371 Triggered release from proteinoid microspheres  
The invention provides proteinoid microsphere made up of a mixture of thermally condensed amino acids that are crosslinked with a bis dithiol crosslinker reagent. The proteinoid microspheres of the...
7229645 Spray freeze-dried compositions  
A process for producing a powder comprises spray freeze-drying an aqueous solution or suspension comprising a pharmaceutical agent, said solution or suspension having a solids content of 20% by...