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7108867 Process for preparing particles  
A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator...
7108864 Tablet formation  
Disclosed is a non-sustained release pharmaceutical tablet composition which comprises a rapidly precipitating drug in an amount from about 5 to about 60% and at least one member selected from the...
7105158 Methods of administering microencapsulated materials for immune modulated diseases  
Compositions useful in treating immune modulated disease comprising an anticytokine antibody or immune active drug capable of modifying cytokine activity or modulating the immune system...
7105176 Production of solid preparations of water-soluble, sparingly water-soluble or water-insoluble active compounds  
A process is described for producing solid preparations of at least one water-soluble, sparingly water-soluble or water-insoluble active compound suitable for the food and animal feed sectors or...
7105182 Periodontal regeneration composition and method of using same  
A periodontal structure regeneration composition for treatment of periodontal disease is a mixture of particles of a bone growth material and free collagen. All particles are sized to be less than...
7101862 Hemostatic compositions and methods for controlling bleeding  
The invention provides hemostatic compositions useful to promote hemostasis at active bleeding wound sites. The hemostatic compositions typically include an article containing cellulose, e.g.,...
7097857 Methods and compositions for the targeted delivery of biologically active agents  
The present invention relates to a sustained release composition for the targeted delivery of biologically active agents to specific tissues and cells. The composition comprises microparticles...
7090830 Drug condensation aerosols and kits  
The present invention provides novel condensation aerosols for the treatment of disease and/or intermittent or acute conditions. These condensation aerosols have little or no pyrolysis degradation...
7090867 Controlled release delivery device for pharmaceutical agents incorporating microbial polysaccharide gum  
The present invention provides a controlled release device for sustained or pulsatile delivery of pharmaceutically active substances for a predetermined period of time. This invention further...
7090862 Method of improving the antioxidant status of an infant  
The present invention relates generally to a method of improving the antioxidant status of an infant. More particularly, the present invention relates to a method of improving the antioxidant...
7087244 Thermogelling oligopeptide polymers  
Disclosed is a thermogelling biodegradable aqueous polymer solution useful in providing a bioactive agent delivery system. A thermogelling biodegradable aqueous polymer solution may comprise a...
7087247 Polyesters, method for producing same, and depot medicaments produced from these polyesters  
The invention relates to novel absorbable polyesters, produced by ring-opening polymerisation of hydroxycarboxylic acids in the presence of a polyol containing an electrolyte, in an extruder. In...
7087246 Controlled release preparation of insulin and its method  
A controlled release preparation of insulin and its method are provided. The controlled release preparation of insulin contains microparticles obtained by microencapsulation of uniform...
7081450 Water soluble nanoparticles of hydrophilic and hydrophobic active materials and an apparatus and method for their production  
This invention provides a soluble nano-sized particles formed of a core (water-insoluble lipophilic compound or hydrophilic compound) and an amphiphilic polymer and which demonstrated improved...
7074430 Controlled release tramadol tramadol formulation  
A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient.
7074427 Medicine, carrier for medicine, method of producing medicine, and method of tumor treatment  
A medicinal preparation capable of lowering the threshold of cavitation and generating active oxygen species via acoustic cavitation caused by an ultrasound is provided. The preparation, which is...
7070765 Delivery of drug esters through an inhalation route  
The present invention relates to the delivery of drug esters through an inhalation route. Specifically, it relates to aerosols containing drug esters that are used in inhalation therapy. In a...
7070809 Hydrogel biomedical articles  
Hydrogel biomedical articles formed from macromers having a polymeric backbone comprising 1,2-diol and/or 1,3-diol units, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups...
7070812 Process for producing dry powders of one or more carotenoids  
The invention relates to a process for producing dry powders of one or more carotenoids by a) dispersing one or more carotenoids in an aqueous molecular or colloidal solution of a mixture of...
7067485 IGF-I composition and its use  
A highly concentrated, low salt-containing, biologically active syrup form of IGF-I or variant thereof and methods for its preparation are provided. This novel syrup form of IGF-I has an IGF-I...
7060255 Delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route  
The present invention relates to the delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route. Specifically, it relates to aerosols containing alprazolam, estazolam,...
7056535 Triggered release from proteinoid microspheres  
The invention provides proteinoid microsphere made up of a mixture of thermally condensed amino acids that are crosslinked with a bis dithiol crosslinker reagent. The proteinoid microspheres of...
7052679 Delivery of antipsychotics through an inhalation route  
The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In...
7052680 Delivery of compounds for the treatment of Parkinsons through an inhalation route  
The present invention relates to the delivery of antiparkinsons drugs through an inhalation route. In a method aspect of the present invention, an antiparkinsons drug is administered to a patient...
7052678 Particles for inhalation having sustained release properties  
The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to...
7052712 Animal feeds including actives and methods of preparing same  
Improved extrusion-processed daily ration animal feeds are provided which include minor amounts of actives to ensure that an animal consuming the feed receives quantities of the actives sufficient...
7048949 Membrane scaffold proteins  
Membrane proteins are difficult to express in recombinant form, purify, and characterize, at least in part due to their hydrophobic or partially hydrophobic properties. Membrane scaffold proteins...
7048908 Particles for inhalation having sustained release properties  
The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to...
7048946 Formulation for controlled release of drugs by combining hyrophilic and hydrophobic agents  
Combinations of hydrophilic and hydrophobic entities in a biodegradable sustained release implant are shown to modulate each other's rate of release. Formulations of a therapeutically active agent...
7048947 Sustained-release preparation  
A sustained-release preparation which comprises a physiologically active peptide of general formula wherein X represents an acyl group; R1, R2 and R4 each represents an aromatic cyclic group;R3...
7045119 Delivery of diazepam through an inhalation route  
The present invention relates to the delivery of compounds for the treatment of anxiety disorders and symptoms of such disorders through an inhalation route. Specifically, it relates to aerosols...
7033609 Microparticle preparation  
A parenterally administrable, biodegradable microparticle preparation containing a biologically active substance which, during the first 24 hours after injection, exhibits a release of the active...
7029700 Micronized freeze-dried particles  
A process is provided for making dry, micronized particles of an agent, such as a drug. The method includes (a) dissolving a macromolecular material, preferably a polymer, in an effective amount...
7030086 Stabilized liquid polypeptide-containing pharmaceutical compositions  
Stabilized liquid polypeptide-containing pharmaceutical compositions are provided. The compositions comprise an amino acid base, which serves as the primary stabilizing agent of the polypeptide,...
7029658 Delivery of antidepressants through an inhalation route  
The present invention relates to the delivery of antidepressants through an inhalation route. Specifically, it relates to aerosols containing an antidepressant that are used in inhalation therapy....
7022313 Hydrogel particle formulation  
New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle...
7022311 Powdery inhalational preparations and process for producing the same  
The present invention is aimed at providing a dry powder inhalation with minimal adhesive-agglomerative property during storage and with a good inhalation behavior for a pharmaceutically active...
7018657 Particulate composition  
Nanoparticles are prepared from a colloidal system comprising a continuous phase and micelles, the micelles comprising surfactant material. A microemulsion is formed by admixing the colloidal...
7018621 Delivery of rizatriptan or zolmitriptan through an inhalation route  
The present invention relates to the delivery of compounds for the treatment of migraine and headache through an inhalation route. Specifically, it relates to aerosols containing rizatriptan or...
7014840 Delivery of sumatriptan, frovatriptan or naratriptan through an inhalation route  
The present invention relates to the delivery of anti-migraine compounds through an inhalation route. Specifically, it relates to aerosols containing sumatriptan, frovatriptan, or naratriptan that...
7011968 Fragments of virus protein 2 or 3 of the polyoma virus, used for transporting active ingredients  
The invention relates to a synthetic, biologically active molecule for fixing an active ingredient to the virus protein 1 (VP1) of the polyoma virus. According to the invention, an amino acid...
7008615 Delivery of anti-migraine compounds through an inhalation route  
The present invention relates to the delivery of anti-migraine compounds through an inhalation route. Specifically, it relates to aerosols containing lidocaine, verapamil, diltiazem,...
7005121 Delivery of compounds for the treatment of migraine through an inhalation route  
The present invention relates to the delivery of a migraine headache drug through an inhalation route. Specifically, it relates to aerosols containing a migraine headache drug that are used in...
7005141 Oral drug delivery compositions and methods  
The present invention relates to an oral drug delivery system, and in particular to modified amino acids and modified amino acid derivatives for use as a delivery system of sensitive agents such...
6994873 Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration  
This invention refers to: multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional release...
6989155 Powders  
Particles of an amino acid such as leucine may be formed from an amino acid vapor, for example by aerosol condensation, or by spray drying. The amino acid particles have a bulk density of not more...
6979467 Microcapsules IV  
A microcapsule having a mean diameter of from about 0.1 to about 5 mm, a membrane and a matrix containing at least one active principle wherein the microcapsule is the product of the process...
6977087 Aerodynamically light particles for pulmonary drug delivery  
Improved aerodynamically light particles for delivery to the pulmonary system, and methods for their preparation and administration are provided. In a preferred embodiment, the aerodynamically...
6972132 System for release in lower digestive tract  
A system whereby a substance which is orally taken and to be delivered into the lower digestive tract is selectively delivered into the lower digestive tract. More particularly, a system which...
6967027 Microfibrillated and/or microcrystalline dispersion, in particular of cellulose, in an organic solvent  
The invention concerns a colloidal dispersion, in an organic solvent, of a microfibrillated and/or microcrystalline particles of a fibrillated organic substance selected among the group consisting...