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6433040 Stabilized bioactive preparations and methods of use  
Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that...
6432381 Methods for targeting drug delivery to the upper and/or lower gastrointestinal tract  
Particulate crystalline therapeutic substances are formulated with stabilizers to enhance contact between the crystalline therapeutic substances and the mucosal membranes to provide extended...
6428812 Process for producing granules containing angiotensin-converting enzyme inhibiting peptides  
Granules and tablets for oral administration, containing angiotensin-converting enzyme inhibiting peptides and treated whey with a mixing fluid bed processor, wherein said whey is obtained from...
6428813 Gastrointestinal mucosa-adherent pharmaceutical composition  
In order to provide a composition having a long gastroduodenal residence time and exhibiting an improved efficacy, is provided a gastrointestinal mucosa-adherent composition comprising an active...
6426088 Encapsulated cells producing antibodies  
The present invention relates to capsules encapsulating antibody-producing cells, and to use of such capsules and encapsulated cells, respectively, for implantation in vivo for long term delivery...
6426087 Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent  
The present invention relates to an orally administrable galenic form allowing improved absorption by the transmembrane or paracellular route in the gastrointestinal tract of active ingredients...
6426077 Food product for health, nutrition and weight management  
A wholesome food product with many uses, for weight control, health and nutrition.
6426317 Stable, high available halogen 1,3,5-triazine-2,4,6-trione compositions having rapid dissolution rates  
Dry, stable, high available halogen sanitizing granular compositions with a rapid rate of dissolution comprising halogenated 1,3,5-triazine-2,4,6-triones and a dissolution accelerant that is an...
6419955 Process for making bisphosphonate compositions  
The present invention relates to a process for the preparation of bisphonate-containing pharmaceutical compositions for oral administration wherein the active substance is wet-granulated in a...
6416787 Quick release compositions  
A dosage form comprises a porous extrudate. The extrudate is obtained by extruding, at elevated temperature, a composition comprising a starch, water, a thermostable enzyme, and a pharmaceutically...
6416739 Microparticles and their therapeutic or diagnostic use  
Microcapsules having a wall thickness of no more than 500 nm, and a bulk density of no more than 0.2 g.cm−3, are suitable for therapeutic or diagnostic use. They are aerodynamically light, and can...
6416788 Oat protein complex and method of use  
A composition containing enhanced colloidal oatmeal which utilizes other avena sativa ingredients to neutralize the discomfort, irritation and inflammation of the skin, as well as maintaining...
6413494 Composition and pharmaceutical dosage form for colonic drug delivery using polysaccharides  
A colonic drug delivery composition contains a first polysaccharide and a second polysaccharide wherein both polysaccharide are degradable by colonic enzymes and are mixed at a environmental pH of...
6413550 Proteinoid carriers and methods for preparation and use thereof  
Improved proteinoid carriers and methods for their preparation and use as oral delivery systems for pharmaceutical agents are described. The proteinoid carriers are soluble within selected pH...
6399103 Method of producing a sustained-release preparation  
A method of producing sustained-release microcapsules which comprises dispersing a physiologically active polypeptide into a solution of a biodegradable polymer and zinc oxide in an organic...
6391307 Composition comprising the lower, no-branch culm portion of bamboo  
An anticancer drug of which the main ingredient is bamboo powder. In particular, the bamboo powder is of lower no-branch culm portions of three-year-old and older bamboos, or is of bamboos cut...
6387408 Adhesive drug delivery composition  
Adhesive material from the fimbriae (esp. Type 1) of bacteria or synthetic analogues or fragments thereof is combined with a drug to provide for attachment to the gut of a mammal, thereby...
6387398 Process for producing cosmetic and pharmaceutical formulations, and products comprising same  
Cosmetic or pharmaceutical formulations such as (a) anhydrous cosmetic stick formulations and (b) anhydrous aerosol spray formulations, comprising an organic dispersion medium having particles...
6379706 Rapidly disintegrating coated pellets with delayed release  
The invention concerns pharmaceutical forms of administration that are in the form of pellets which contain a retarding agent in which the release rate of the active substance is not delayed or is...
6379707 Method of making granular pharmaceutical vehicle  
A formulation of a sparingly water-soluble, crystalline pharmaceutically active agent wherein the active agent is converted to and stabilized in its amorphous form as a solid solution of a...
6376461 Sustained-release preparation  
According to a first embodiment, there is provided a sustained-release preparation comprising a water-insoluble or slightly water-soluble polyvalent metal salt of a water-soluble physiologically...
6375988 Drug composition with controlled drug release rate  
This invention relates to a drug composition with a controlled drug release rate. The drug composition comprises: a matrix formed of the following ingredients (a) and (b):(a) a biodegradable,...
6369115 Stabilized powder formulations  
A dry powder formulation for treatment of pulmonary conditions, via inhalation, includes an effective amount of formoterol or a salt or solvate thereof, in a dry powder form, an effective amount...
6368633 Microparticles which controllably release olfactorily active substances, methods of using same and processes for preparing same  
Described are flavor composition, flavor component, perfume composition and perfume component-containing microparticles which are particulate matrices composed of: (a) an olfactorily active...
6368634 High release solid preparation, preparation and use thereof  
A solid preparation for a substantially immediate release of an active agent with low or very low solubility, which contains the active agent dissolved in a solubilizer, said dissolved active...
6365189 Method of delivering and releasing a pheromone  
A microbead having a matrix core comprising a hydrophilic matrix and droplets of active material entrained therein, and a secondary layer adjacent to the outer surface of the matrix core. The...
6358530 Powdered pharmaceutical formulations having improved dispersibility  
Dispersibility of a respirable powder, administrable by inhalation, is increased by including a pharmaceutically acceptable water-soluble polypeptide.
6355271 Therapeutic calcium phosphate particles and methods of manufacture and use  
Novel calcium phosphate core particles, methods of making them, and methods of using them as vaccine adjuvants, as cores, as carriers of biologically active material, and as controlled release...
6352738 Diverticulitis-sparing nut-based snack products and method of making  
Nut-based products are prepared by reconsolidating ground nuts of all small particle size by means of one or more consolidating binders, preferably water soluble binders. The particle size is...
6350779 Piece-form calcium formate  
Piece-form materials which comprise 5-100% by mass calcium formate and 95-0% by mass additives and have particle sizes of 0.2-5 mm can be prepared from finely crystalline calcium formate and the...
6348207 Orally deliverable supramolecular complex  
Methods for transporting a biologically active agent across a cellular membrane or a lipid bilayer. A first method includes the steps of: (a) providing a biologically active agent which can exist...
6335457 Complex containing biologically assimilable orthosilicic acid, which is under solid form, stable and concentrated, and a process for preparation of said complex  
The invention concerns a complex containing biologically assimilable orthosilicic acid and a process of preparation of said complex. In this complex, orthosilicic acid is complexed with a...
6331315 Powder compositions of unilamellar liposomes  
The invention concerns powder compositions of stabilised unilamellar liposomes, comprising at least an external lipid phase and a internal aqueous polar nucleus gelled at room temperature, the...
6328996 Bioelastomeric drug delivery system  
A drug delivery composition, comprising a bioelastic polymer, comprising monomeric units selected from the group consisting of bioelastic pentapeptides, tetrapeptides, and nonapeptides, and a drug...
6328995 Stable vitamin and/or carotenoid products in powder form and process for their production  
Stable dry powders which are insoluble in hot water and which contain one or more lipid-soluble vitamins an/or one or more carotenoids are formed in an aqueous dispersion containing 2 to 50% by...
6326027 Controlled release formulation  
A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient.
6322818 Starch granulation  
The present invention relates to starch granules made completely on the basis of starch and to a process for producing these granules. The process comprises the use of a slurry of pregelatinised...
6309663 Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents  
The present invention relates to pharmaceutical compositions, pharmaceutical systems, and methods for enhanced absorption of hydrophilic therapeutic agents. Compositions and systems of the present...
6306406 Drug delivery system involving interaction between protein or polypeptide and hydrophobic biodegradable polymer  
A drug delivery system for controlled release of a protein or polypeptide comprising a hydrophobic biodegradable polymer and a protein or polypeptide. A physical interaction is present between the...
6306440 Therapeutic preparation for inhalation  
A therapeutic preparation for inhalation which comprises insulin and a substance which enhances the absorption of insulin in the lower respiratory tract, is provided in the form of a powder...
RE37410 Controlled local delivery of chemotherapeutic agents for treating solid tumors  
A method and devices for localized delivery of a chemotherapeutic agent to solid tumors, wherein the agent does not cross the blood-brain barrier and is characterized by poor bioavailability...
6303150 Method for producing nanocapsules with crosslinked protein-based walls nanocapsules thereby obtained and cosmetic, pharmaceutical and food compositions using same  
A method for producing nanocapsules with cross-linked protein-based walls, comprising preparing emulsions of said proteins and crosslinking these with a crosslinking agent having reactive groups...
6299907 Reversibly swellable starch products  
Reversible swellable modified starch products are provided in the form of individual, chemically cross-linked starch granules capable of undergoing multiple hot or cold water swelling/drying...
6296873 Zero-order sustained release delivery system for carbamazephine derivatives  
A zero-order sustained-release delivery system for delivery of carbamazepine or a derivative thereof. A polymeric matrix formulation of carbamazepine comprises hydrophilic polymer or...
6290990 Slow-release matrix pellets and the production thereof  
Slow-release matrix pellets with a spherical or lenticular shape and uniform maximum diameters in the range from 0.5 to 4 mm, composed of a) 0.1-87% by weight of at least one biologically active...
6284282 Method of spray freeze drying proteins for pharmaceutical administration  
The present invention relates to the spray freeze dry preparation of dry powder formulations of therapeutic proteins suitable for administration via pulmonary delivery.
6284269 Pharmaceutical compositions of meloxicam with improved solubility and bioavailability  
Pharmaceutical compositions containing enolic carboxamide type antiinflammatory agent meloxicam that exhibit improved wettability, aqueous solubility, dissolution behaviour over a broad range of...
6281341 Hetero-polysaccharide conjugate and methods of making and using the same  
Disclosed and claimed are: a composition including at least one glycosaminoglycan, e.g., CIS, and at least one alginate, e.g., sodium alginate, wherein: the at least one glycosaminoglycan and/or...
6280759 Method of controlled release and controlled release microstructures  
Tubules which contain an active agent in their lumen and compositions containing such microtubules are effective for providing a slow, controlled release of the active agent. Such microtubules are...
6267981 Method of producing sustained-release preparation  
This invention provides a sustained-release preparation comprising a biodegradable polymer metal salt and broactive polypeptide, with enhanced entrapment of the bioactive polypeptides, a...