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9040080 Processing of heat-sensitive active agents  
The present disclosure relates to a method of melt processing an active agent. The method may include encapsulating an active agent in a first polymer material exhibiting a first processing...
9034902 Methods for treatment of attention deficit hyperactivity disorder  
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of...
9023389 Compositions for treatment of attention deficit hyperactivity disorder  
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of...
9017644 Methods of treating autoimmune disorders and/or inflammatory disorders  
The present invention relates to dendrimer compositions configured for treating inflammatory disorders and autoimmune disorders, and related methods of synthesis. Specifically, the present...
9011927 Pentablock polymers  
Novel pentablock polymers comprising PGA-PCL-PEG-PCL-PGA or PEG-PCL-PLA-PCL-PEG, wherein PEG is polyethylene glycol, PCL is poly(ε-caprolactone), PGA is poly(glycolic acid), and PLA is poly(lactic...
9012363 Granular controlled release agrochemical compositions and process for the preparation thereof  
A granular agrochemical composition is disclosed including a granular core material having a water soluble portion with a first coating layer applied on the surface of the core material and a...
9005666 Process for preparing lipid nanoparticles  
A process for preparing nanocapsules with a liquid lipid core and a solid lipid shell, charged with at least one active agent. The process contains at least the steps of formulating a...
9005658 Oral preparation with controlled release  
A pharmaceutical pellet is provided, comprising a spherical core containing the active substance with a smooth surface and a coating on the core, which controls pH-independent release of the...
8999390 Sustained release formulation comprising octreotide and three linear polylactide-co-glycolide polymers  
The present invention relates to sustained release formulations comprising as active ingredient octreotide or a pharmaceutically-acceptable salt thereof and three different linear...
8992991 Multicomponent degradable cationic polymers  
Degradable polymers were synthesized that self-assemble with DNA to form particles that are effective for gene delivery. Small changes to polymer synthesis conditions, particle formulation...
8992990 Magnetic nanocomposite for inhibiting/treating cancer and method for fabricating the same  
The present invention discloses a magnetic nanocomposite for inhibiting/treating cancer and a method for fabricating the same. The magnetic nanocomposite comprises a core formed of a plurality of...
8992988 Coating film, and granules and tablets each utilizing same  
A coating film comprising ethyl cellulose as a component A and an (ethyl acrylate)-(methyl methacrylate) copolymer or a plasticized vinyl acetate polymer as a component B, and having a tensile...
8975273 Controlled release hydrocodone formulations  
A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt...
8975271 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Controlled release hydrocodone formulations
 
A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt...
8974769 Magnetic nanocomposite with multi-biofunctional groups and method for fabricating the same  
The present invention proposes a magnetic nanocomposite with multi-biofunctional groups, which comprises a core and a shell wrapping the core, wherein the core contains magnetic nanoparticles, and...
8968778 Threo-DOPS controlled release formulation  
The present invention relates to pharmaceutical formulations for the controlled delivery of threo-3-(3,4-dihydroxyphenyl)serine (threo-DOPS) and derivatives of it. Such formulations can contain an...
8961936 Ultrasonography using time- and temperature-sensitive variable adhesion coupling gels  
One aspect of the present invention relates to a method of ultrasonography, utilizing a gel comprising a reverse phase polymer which facilitates the transmission of high-frequency sound waves....
8962025 Rapidly acting dry sealant and methods for use and manufacture  
Compositions, methods, and kits are provided for sealing applications. Compositions are prepared by combining a first cross-linkable component with a second cross-linkable component to form a...
8956662 Phenylephrine pharmaceutical formulations and compositions for colonic absorption  
The invention discloses a pharmaceutical composition comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is for oral administration wherein the...
8951558 Aqueous carbonated medium containing an amino(meth)acrylate polymer or copolymer  
The invention relates to an aqueous medium containing an amino(meth)acrylate polymer or copolymer which is not soluble in dematerialised water, characterized in that the medium has a content of an...
8951567 Sol-gel phase-reversible hydrogel templates and uses thereof  
Discrete microstructures of predefined size and shape are prepared using sol-gel phase-reversible hydrogel templates. An aqueous solution of hydrogel-forming material is covered onto a...
8951569 Pellets coated with coatings containing active substances  
Formulations of sparingly water-soluble active ingredients, consisting of carrier particles provided with active ingredient-containing coatings, the sparingly soluble active ingredients being...
8951554 Microcapsule, structure having a microcapsule, article having a microcapsule, and method of preparing microcapsules  
A microcapsule, a structure including a microcapsule, an article including a microcapsule and a method of preparing microcapsules provided, the microcapsule includes at least one material selected...
8951568 Granule and preparation method thereof  
A pharmaceutical granule whose shape is spherical or sphere-like shape with a bulk density of 0.6-1.3 g/ml and a dissolution time of 0.5-5 minutes, which is prepared as follows: mother granules...
8945629 Nanoparticles for cytoplasmic drug delivery to cancer cells  
The invention is a nanoparticle that contains an anticancer drug that is released in cancer cells when administered to a subject. The nanoparticles have a core including the anticancer drug and...
8945610 Condensation products based on bicyclic or polycyclic aromatics or heteroaromatics  
The invention relates to a condensation product obtainable by reaction of a1) at least one bicyclic or polycyclic aromatic or heteroaromatic, where the bicyclic or polycyclic aromatic or...
8940336 Polymer particles prepared from polymerisable alkylene glycol (meth) acrylate monomers  
The invention provides polymer particles that are obtainable by a method selected from emulsion methods, diffusion methods and evaporation methods carried out in the presence of...
8932639 Compositions comprising solid particles encapsulated in a cross-linked silicone matrix, and methods of making the same  
The present invention relates to topical compositions containing solid particles that are stabilized via encapsulation into a cross-linked silicone matrix. The stabilized particles possess an...
8927026 Shampoo compositions with increased deposition of polyacrylate microcapsules  
A shampoo composition that increases the deposition and retention of benefit agent containing polyacrylate microcapsules onto hair during the cleansing process. The shampoo composition is based on...
8927010 Compositions for treatment of attention deficit hyperactivity disorder  
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of...
8927025 Alcohol-resistant metoprolol-containing extended-release oral dosage forms  
This disclosure relates to an extended release oral dosage form comprising a matrix containing a viscosity modifier (but no lipid) and coated granules containing metoprolol or a pharmaceutically...
8916588 Methods for treatment of attention deficit hyperactivity disorder  
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of...
8906410 Oral dosage form of 25-hydroxyvitamin D  
Methods and compositions for treating 25-hydroxyvitamin D insufficiency and deficiency in a patient are described herein. The method includes orally administering to the patient a delayed,...
8895067 Immune response stimulating composition comprising nanoparticles based on a methyl vinyl ether-maleic acid copolymer  
The composition for stimulating an immune response in a subject comprises methyl vinyl ether and maleic anhydride copolymer-based nanoparticles. Said nanoparticles may further contain an allergen...
8895073 Hydrogel implant with superficial pores  
Implantable biomaterials, particularly hydrogel substrates with porous surfaces, and methods for enhancing the compatibility of biomaterials with living tissue, and for causing physical attachment...
8889161 Microencapsulated compositions and methods for tissue mineralization  
The present invention is directed to compositions, products and methods useful for bone and tooth mineralization. The compositions comprise polymer microcapsules containing aqueous salt solutions....
8889192 Magnetic nanomedicine for inhibiting/treating human prostate cancer  
The present invention discloses a magnetic nanomedicine for inhibiting/treating human prostate cancer, which comprises a core containing a magnetic particle having a diameter of less than 10 nm; a...
8889193 Sustained delivery of therapeutic agents to an eye compartment  
Compositions and methods for treating eye disorders by administering a drug delivery system into an eye compartment of the patient, wherein the drug delivery system contains a particle containing...
8889185 Modified release compositions comprising tacrolimus  
A modified release composition comprising tacrolimus which is useful for the treatment or prevention of rejection reactions by transplantation of organs or tissues.
8877247 Abuse-deterrent multi-layer pharmaceutical composition comprising an opioid antagonist and an opioid agonist  
Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one...
8877250 Hollow nano-particles and method thereof  
The invention provides a hollow nano-particle comprising a crosslinked shell and a void core; and a preparation method thereof. The hollow nano-particle may be used in rubber composition, tire...
8871235 Compositions and their use in bone healing  
The present invention is directed to implantable compositions comprising substantially spherical bioactive glass particles.
8865221 Swellable and degradable microspheres  
Swellable and degradable microspheres are described. The microspheres are prepared by a process that is reliable and high yielding, and makes use of a low temperature azo initiator, a small...
8865220 Method for controlled release of parathyroid hormone from encapsulated poly(lactic-glycolic)acid microspheres  
The present invention provides a method for producing a controlled release microsphere with mean average size greater than 50 μm, comprising preparing a water-in-oil (w/o) emulsion comprising an...
8859288 pH-sensitive microparticles with matrix-dispersed active agent  
Methods to produce pH-sensitive microparticles that have an active agent dispersed in a polymer matrix have certain advantages over microcapsules with an active agent encapsulated in an interior...
8852624 Biomedical implants comprising surface-modified ceramic particles and biodegradable stereo complex polymers, its use for suppressing inflammation and improvement of mechanical property, and preparation method thereof  
A biomedical implant according to this invention comprises ceramic complex, which includes a surface-modified basic ceramic particles, which are basic ceramic particles modified their surface with...
8852626 Controlled-release CNS modulating compositions and methods for the treatment of otic disorders  
Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an...
8846104 Pharmaceutical compositions for the deterrence and/or prevention of abuse  
Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one...
8828429 Release-control composition  
The present invention relates to a controlled release capsule preparation for oral administration, which contains (i) a granule containing a physiologically active substance which is a compound...
8828440 Corticosteroids for the treatment of joint pain  
Corticosteroid microparticle formulations are provided for use for treating pain, including pain caused by inflammatory diseases such as osteoarthritis or rheumatoid arthritis, and for slowing,...