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7604820 |
Solid preparation containing chitosan powder and process for producing the same
A colonic delivery solid preparation containing chitosan powder, which can control the dissolution of a medicament therefrom in the large intestine and release the medicament contained therein...
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7582311 |
Injection vehicle for polymer-based formulations
The invention provides injection vehicles suitable for administering particulate suspensions, such as polymer-based formulations, as well as associated pharmaceutical formulations, articles of...
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7569236 |
Sustained-release microgranules containing gingko biloba extract and the process for manufacturing these
The subject of the present invention is a new stable herbal drug formulation in the form of sustained-release microgranules containing Gingko Biloba extract as well as the process for preparing it.
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7563456 |
Process for preparation of programmed liberation composition with venlafaxine and the resulting product
Process for the preparation of programmed liberation compositions with venlafaxine and the resulting product, from which the resulting product allows a better absorption of the active principle and...
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7547452 |
Microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
Sustained-release microparticle composition. The microparticle composition can be formulated to provide extended release over a period of from about 7 days to about 200 days. The microparticles may...
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7544673 |
Coating compositions for bioactive agents
A coating composition and related method for use in applying a bioactive agent to a surface in a manner that will permit the bioactive agent to be released from the coating in vivo. The composition...
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7541347 |
Minocycline oral dosage forms for the treatment of acne
Minocycline oral dosage forms containing a controlled release carrier are useful for the treatment of acne.
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7531334 |
Polymeric microcarriers for cell culture functions
Polymeric microcarriers suitable for use in cell culture processes and the methods of making such polymeric microcarriers by emulsion/aggregation polymerization processes.
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7510731 |
Water-soluble stabilized self-assembled polyelectrolytes
The present invention is directed toward water-soluble supramolecular self-assemblies and a process for their preparation via micellization of polyelectrolytes through the use of hydrophobic...
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7473431 |
Injectable methadone, methadone and naltrexone, or buprenorphine and naltrexone microparticle compositions and their use in reducing consumption of abused substances
An injectable slow-release methadone, partial opioid agonist or opioid antagonist formulation is provided comprising methadone, a partial opioid agonist or opioid antagonist in a poly(D,L-lactide)...
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7465463 |
Compositions comprising microspheres with anti-inflammatory properties for healing of ocular tissues
The present invention relates to compositions of microspheres suitable for application to ocular injuries and inflammation, and to methods of use of the compositions alone or in combination with...
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7445796 |
Pharmaceutically active particles of a monomodal particle size distribution and method
A method of obtaining improved reproducibility of dissolution profiles of dosage forms containing pharmaceutically active particles includes steps of screening raw pharmaceutically active particles...
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7442385 |
Chemoembolisation
A composition for chemoembolotherapy of solid tumours comprises particles of a water-insoluble water-swellable synthetic anionic polymer and, absorbed therein an anthracycline. Suitably the polymer...
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7438930 |
Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations
The invention is directed to oral modified/controlled release drug formulations which provide a rapid initial onset of effect and a prolonged duration of effect. Preferably, the peak concentration...
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7431944 |
Delivery of multiple doses of medications
Dosage forms for oral administration of a methylphenidate drug are provided. The dosage forms provide a substantially immediate dose of methylphenidate upon ingestion, followed by one or more...
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7431943 |
Controlled release and taste masking oral pharmaceutical compositions
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic,...
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7427415 |
Implantation of encapsulated biological materials for treating diseases
The present invention relates to compositions and methods of treating a disease, such as diabetes, by implanting encapsulated biological material into a patient in need of treatment. This invention...
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7425528 |
Stabilization of granules
The present invention relates to granules comprising a core matrix and one or more coatings, wherein the core matrix comprises: An active compound, a synthetic polymer, where the amount of polymer...
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7423004 |
Solid dispersion compositions
Disclosed is a water-dispersible solid composition of a sparingly water-soluble compound in a particulatable lipidic carrier, methods for the preparation and use of the same. The compositions of...
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7422758 |
Sustained release vitamin composition
A therapeutic formulation in the form of a beadlet, suitable for oral administration and adapted to provide immediate and sustained release of therapeutic material. Each beadlet comprises an...
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7413750 |
Process for producing solid oral dosage forms with sustained release of active ingredient
The present invention relates to a process for producing solid oral dosage forms with sustained release of active ingredient, comprising at least one active ingredient, a preformulated mixture of...
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7408018 |
Elastomeric functional biodegradable copolyester amides and copolyester urethanes
The invention provides elastomeric copolyester amides, elastomeric copolyester urethanes, and methods for making the same. The polymers are based on α-amino acids and possess physical, chemical...
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7390504 |
HDL-boosting combination therapy complexes
A pharmaceutical composition including therapeutically effective amounts of at least one HMG-CoA reductase inhibitor present as a dyhydroxyacid salt and at least one additional therapeutic agent.
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7338928 |
System for releasing encapsulated active ingredients
The present invention relates to a controlled release system that can be incorporated in cosmetic, personal care, and household products to effectively encapsulate wide range of active ingredients...
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7323540 |
Process for preparing microrods using liquid-liquid dispersion
The invention provides a method for forming polymer microrods, the method including the steps of providing a polymer solution comprising a polymer dissolved in a first solvent; providing a...
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7316818 |
Liposome drug delivery of polycyclic, aromatic, antioxidant or anti-inflammatory compounds
This invention comprises pharmaceutical compositions for administering a polycyclic, aromatic, antioxidant or anti-inflammatory compound to an animal. Particularly provided are proliposomal...
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7309500 |
Microparticles
A method of forming particles, comprises accelerating a first stream comprising a first liquid, applying a charging voltage of at most 1.5 kV to the first stream, and vibrating the first stream, to...
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7303767 |
Personal care compositions comprising coated/treated metal silicate absorbent particles
Coated particles of metal (such as calcium) silicate that exhibit excellent odor neutralization and sebum absorption properties when present within certain cosmetic and/or personal care...
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7303766 |
Coated/treated metal silicate absorbent particles
Coated particles of metal (such as calcium) silicate that exhibit excellent odor neutralization and sebum absorption properties when present within certain cosmetic and/or personal care...
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7282221 |
Antiviral product, use and formulation thereof
An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the C max for the antiviral product being reached in less than about twelve...
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7276254 |
Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same
A method of forming polymeric microspheres for biomedical applications includes forming polymeric microspheres by an emulsion/aggregation process from a precursor monomer species, and treating the...
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7270831 |
Orally administrable opioid formulations having extended duration of effect
Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for...
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7255877 |
Fenofibrate microparticles
Fenofibrate microparticles are prepared using a combination of surface modifiers with a phospholipid. Particle size growth and stability are controlled while significantly smaller sized fenofibrate...
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7241458 |
Antiviral compositions
The present invention is concerned with pharmaceutical compositions of antiviral compounds which can be administered to a mammal, in particular a human, suffering from a viral infection. These...
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7235261 |
Controlled release encapsulation
This invention relates to a controlled release encapsulated dry powder that is formed by an emulsion comprising: A) a fully hydrolyzed polymer, B) a hydrophobic silica, C) a modified corn starch,...
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7235260 |
Pharmaceutical compositions of a sparingly soluble glycogen phosphorylase inhibitor
Pharmaceutical compositions of a particularly effective sparingly soluble glycogen phosphorylase inhibitor are disclosed, as well as methods of making such compositions and dosage forms from such...
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7226622 |
Chemoablation of tissue using biodegradable, solid salt dosage forms
Novel methods for the chemical ablation of tissue (e.g. prostatic tissue) are described. These methods include the steps of: (a) providing one or more solid salt dosage form comprising 50-100% w/w...
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7226620 |
Directly compressible tricalcium phosphate
A compressible tricalcium phosphate agglomerate comprises tricalcium phosphate particles, each having an outer surface, and a binder comprising a polyvinylpyrollidone, carrageenan, or a guar gum,...
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7223421 |
Teste masked pharmaceutical particles
Taste masked particles and chewable tablets made therefrom are disclosed. The taste masked particles comprise a core containing an active ingredient and a polymeric coating covering said core, said...
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7217431 |
Controlled agglomeration
A process for the preparation of a particulate material by a controlled agglomeration method, i.e. a method that enables a controlled growth in particle size. The method is especially suitable for...
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7211615 |
Polyamide powder with long-lasting, consistently good flowability
A composition containing from 88 to 99.99% by weight of a polyamide, a compound of a polyamide and mixtures of these, and from 0.01 to 0.25% by weight of a flow aid where the drying loss from the...
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7195769 |
Pharmaceutical compositions of anti-tubercular drugs and process for their preparation
A pharmaceutical composition of anti-tubercular drugs for oral use comprising Rifampicin and/or Isoniazid wherein the bioavailability of Rifampicin and/or other drugs is enhanced. Preferably the...
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7192608 |
Method of manufacturing drug granules, the drug granules and pharmaceutical preparation containing the drug granules
The present invention provides coated granules using drug granules containing a water soluble drug as an active ingredient at a high density, which is superior in uniform content and stability, and...
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7186459 |
Liposome coated with polyhydroxyalkanoate and production method thereof
A structure, which has both a drug holding capability and a sustained release ability utilizing a liposome and mechanical strength of a polyhydroxyalkanoate. This structure is excellent in holding...
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7157102 |
Multi-layered microcapsules and method of preparing same
A multi-layered microcapsule containing one or more active ingredients and process for preparing the same is disclosed. The multi-layered microcapsule comprises an inner solid microparticle core,...
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7147917 |
Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media
Water-dispersible nanoparticles are prepared by applying a coating of a multiply amphipathic dispersant to the surface of a hydrophobic nanoparticle comprised of a semiconductive or metallic...
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7138143 |
Coated preparation soluble in the lower digestive tract
A coating dispersion soluble in the lower digestive tract which is prepared by blending a hydroxypropyl methylcellulose acetate succinate (HPMCAS) soluble at around pH 7 with a conventional...
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7125567 |
Process for producing an oral sustained-release preparation of fasudil hydrochloride
Disclosed is an oral sustained-release preparation which contains at least one active ingredient selected from the group consisting of fasudil hydrochloride and a hydrate thereof, the preparation...
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7122206 |
Aqueous-based pharmaceutical composition
An aqueous pharmaceutical composition which is capable of being sprayed into the nasal cavity of an individual and which comprises: (A) a pharmaceutically effective amount of solid particles of...
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7108867 |
Process for preparing particles
A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator...
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