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7108867 |
Process for preparing particles
A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator...
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7105181 |
Microparticles
A process for producing parenterally administrable microparticles, in which an at least 20% by weight aqueous solution of purified amylopectin-based starch of reduced molecular weight is prepared,...
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7101576 |
Nanoparticulate megestrol formulations
The present invention is directed to nanoparticulate compositions comprising megestrol. The megestrol particles of the composition have an effective average particle size of less than about 2000 nm.
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7101566 |
Polymer coated microparticles for sustained release
The present invention is directed to sustained release microparticle formulation for parenteral administration of biologically active substances, especially drugs. More specifically it relates to...
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7097857 |
Methods and compositions for the targeted delivery of biologically active agents
The present invention relates to a sustained release composition for the targeted delivery of biologically active agents to specific tissues and cells. The composition comprises microparticles...
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7087246 |
Controlled release preparation of insulin and its method
A controlled release preparation of insulin and its method are provided. The controlled release preparation of insulin contains microparticles obtained by microencapsulation of uniform microcystals...
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7083748 |
Method and apparatus for continuous particle production using supercritical fluid
A method and an apparatus for continuously producing particles from an emulsion by supercritical fluid extraction. The emulsion includes a solute suspended or dissolved in the supercritical fluid...
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7074417 |
Multiple-delayed release anti-viral product, use and formulation thereof
An anti-viral product is comprised of at least three delayed release dosage forms, each of which has a different release profile, with the C max for the anti-viral product being reached in less...
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7074427 |
Medicine, carrier for medicine, method of producing medicine, and method of tumor treatment
A medicinal preparation capable of lowering the threshold of cavitation and generating active oxygen species via acoustic cavitation caused by an ultrasound is provided. The preparation, which is...
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7067153 |
Microcapsule powder
A process for making hydrophobicized powders of micro- and/or nanocapsules involving the steps of: (a) providing an aqueous polymer solution containing at least one active ingredient and at least...
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7048947 |
Sustained-release preparation
A sustained-release preparation which comprises a physiologically active peptide of general formula
wherein X represents an acyl group;
R 1 , R 2 and R 4 each represents an aromatic cyclic...
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7045146 |
Templating of solid particles by polymer multilayers
Process for encapsulation of an uncharged crystalline solid particle include treating the crystalline solid particle material with amphiphilic substances and subsequently coating the material with...
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7041320 |
High drug loaded injectable microparticle compositions and methods of treating opioid drug dependence
Methods and compositions to induce opioid drug independence in opioid drug dependent individuals comprising administering opioid agonists and/or antagonists encapsulated in biodegradable polymer...
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7037529 |
Fenofibrate pharmaceutical composition having high bioavailability and method for preparing it
The invention provides an immediate-release fenofibrate composition comprising (a) an inert hydrosoluble carrier covered with at least one layer containing fenofibrate in a micronized form having a...
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7034037 |
Compositions and medical devices utilizing bioabsorbable polymeric waxes and rapamycin
The present invention is directed to medical devices and pharmaceutical or agricultural compositions, and seeds, each containing a synthetic, bioabsorbable, biocompatible polymeric wax that is the...
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7029699 |
Soft chewable tablets
The present invention relates to a compressed, chewable tablet containing at least one active ingredient, a water-disintegratable, compressible carbohydrate and a binder. These components are dry...
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7018658 |
Pharmaceutical pellets comprising tamsulosin
Tamsulosin pellets having an advantageous release profile are formed. The pellets have an enteric coating and release less than 10% of the tamsulosin in two hours in SGF.
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7008640 |
Pharmaceutical composition for oral use with improved absorption
The present invention presents a pharmaceutical composition for oral use with improved absorption, which comprises drug, aminoalkyl methacrylate copolymer E, and acidic substance and is obtained by...
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7001589 |
Composite nanospheres and their conjugates with biomolecules
The invention concerns composite nanospheres having a diameter ranging between about 50 and 1000 nm plus or minus 5%, preferably between about 100 and 500 nm plus or minus 5% and advantageously...
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7001616 |
Microspheres for use in the treatment of cancer
The subject invention pertains to novel materials and methods for use in treating patients afflicted with oncological disorders, such as tumors. One aspect of the invention concerns methods for...
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6994873 |
Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration
This invention refers to:
multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional...
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6992047 |
Method of microencapsulating an agricultural active having a high melting point and uses for such materials
A method of producing a controlled release form of an agricultural active material includes the provision of an organic liquid composition in which the active is present, but where the liquid...
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6989159 |
Pharmaceutical compositions containing lithium carbonate
Once daily pharmaceutical compositions containing lithium carbonate in the form of coated granules.
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6984402 |
Chrono delivery formulations and method of treating atrial fibrillation
A dosage formulation for once daily administration prior to sleeping is described that provides an initial delay in pharmaceutical release followed by controlled release of the pharmaceutical....
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6984404 |
Methods for preparing coated drug particles and pharmaceutical formulations thereof
Disclosed are methods using pulsed laser ablation to prepare coated drug particles of uniform size and thickness. The coated drug particles ranged in size from several nanometers to several...
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6979466 |
Nanoscale particles having an iron oxide-containing core enveloped by at least two shells
The invention relates to nanoscale particles suited especially for use in tumor therapy by hyperthermia. Said particles comprise a (preferably superparamagnetic) iron oxide-containing core and at...
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6974592 |
Encapsulated agglomeration of microcapsules and method for the preparation thereof
Microcapsules comprising an agglomeration of primary microcapsules, each individual primary microcapsule having a primary shell and the agglomeration being encapsulated by an outer shell, may be...
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6974593 |
Insoluble drug delivery
Particles of water insoluble biologically active compounds, particularly water-insoluble drugs, with an average size of 100 nm to about 300 nm, are prepared by dissolving the compound in a solution...
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6969530 |
Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
Described herein are microcapsules and emulsions prepared from low Bloom gelatin and methods of making and using thereof.
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6964780 |
Controlled-release pharmaceutical formulations
The invention provides controlled-release formulations for oral administration containing a cGMP PDE-5 inhibitor. The formulations are useful, inter alia, in the treatment or prevention of sexual...
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6962717 |
Pharmaceutical compositions
A pharmaceutical composition for slow release of active ingredient in the gastrointestinal tract, comprising a plurality of active ingredient-containing particles coated with a material insoluble...
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6958161 |
Modified release coated drug preparation
A modified release preparation having one or more coated core elements, each core element including an active ingredient and having a modified release coating, wherein a stabilising coat is...
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6956043 |
Pharmaceutical compositions comprising 33-epi-chloro-33-desoxy-ascomycin solid dispersions
A pharmaceutical composition in the form of a solid dispersion comprising a macrolide, e.g. a rapamycin or an ascomycin, and a carrier medium.
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6951657 |
Particles coated with granulated crystalline ibuprofen
The invention concerns coated particles based on granulated microcrystals of ibuprofen, its pharmaceutically acceptable isomers and salts, characterized in that they comprise a coating obtained in...
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6951745 |
Polyhydroxyalkanoate-containing structure and manufacturing method thereof
A method for manufacturing polyhydroxyalkanoate-containing structure, at least a part of a base material surface of the structure being coated with polyhydroxyalkanoate, the method comprises the...
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6946146 |
Coating for a sustained release pharmaceutical composition
The present invention is directed to a coating composition for coating a solid dosage form of a medicament, where the coating composition controls the release of the medicament, said coating...
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6939560 |
Pharmaceutical composition having two coating layers
The present invention provides a pharmaceutical composition which is substantially free of unpleasant tastes and orally administrable which comprises:
(a) an active medicament, (b) an inner...
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6936278 |
Microparticles
A process for producing microparticles, in which an aqueous solution of purified amylopectin-based starch of reduced molecular weight is prepared, the solution is combined with biologically active...
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6932984 |
Method of microencapsulation
A method for microencapsulation of substances is provided. The substance(s) is/are dissolved or dispersed in an organic solvent of the kind that is partially miscible in water media. This organic...
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6933380 |
Excipients containing low residual solvent and method for producing the same
The present invention provides low-residual-solvent containing excipients with residual solvent less than <3000 ppm. Most of the excipients are required to first be modified to become more water...
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6926909 |
Chrono delivery formulations and method of use thereof
A dosage formulation for once daily administration prior to sleeping is described that provides an initial delay in pharmaceutical release followed by controlled release of the pharmaceutical....
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6921541 |
Formulations and methods for providing prolonged local anesthesia
A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible,...
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6911217 |
Controlled release bead, a method of producing the same and multiple unit formulation comprising it
A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble...
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6900162 |
Slow release nitrogen coating
A coated aggregate material for enhancing the extended delivery of nitrogen needed for plant development and growth, the coated aggregate material having a slow release (extended-release) nitrogen...
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6861016 |
Apparatus and method for preparing microparticles
Apparatus and method for preparing microparticles. An emulsion is formed by combining two phases in a static mixing assembly. The static mixing assembly preferably includes a preblending static...
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6855335 |
Process for preparing silica microcapsules
The present invention relates to a process for preparing silica microcapsules and more particularly, to a process for preparing silica microcapsules comprising the steps of dissolving tetraethyl...
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6852312 |
Biocidal polystyrene hydantoin particles
Method for preparing biocidal halogenated polystyrene hydantoins. The biocidal polymers poly-1,3-dichloro-5-methyl-5-(4′-vinylphenyl)hydantoin,...
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6853477 |
Particles for electrophoresis, a production method thereof and a display using the particles
Electrophoretic particles for electrophoretic display having excellent dispersibility and dispersion stability with time for insulating media, and being protected against coagulation, settling and...
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6852336 |
Directly compressible high load acetaminophen formulations
Direct compressed solid pharmaceutical dosage forms containing:
a) from about 40 to about 95% by weight acetaminophen; b) from about 1 to about 60% by weight of a direct compression vehicle...
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6849269 |
Proliposomal drug delivery system
This invention relates to proliposomal drug-delivery systems for medicaments. In particular, it relates to enteric-coated proliposomal formulations for poorly water soluble drugs and methods for...
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