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5431921 |
Dispensing device containing a hydrophobic medium
A device for the controlled delivery of an insoluble or partially aqueous insoluble beneficial agent to an aqueous containing environment. The device comprises a shaped wall that surrounds and...
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5431920 |
Enteric coated oral compositions containing bisphosphonic acid antihypercalcemic agents
The present invention relates to a novel oral dosage form of a bisphosphonic active ingredient for use in treatment of diseases involving bone resorption and formulated in an enteric-coated form...
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5427800 |
Process for preparation of an extract of active ingredients in a dry adsorbable form and adsorbable form and adsorbable microgranules thus obtained
A process for the preparation of a dry adsorbable extract of at least one active ingredient, comprising the steps of: first, preparing an extract of the active ingredient in a solvent medium...
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5423337 |
Medicated dental floss
Dental floss having a wax or similar caoting impregnated with a nascent oxygen generating agent such as calcium peroxide.
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5417982 |
Controlled release of drugs or hormones in biodegradable polymer microspheres
A controlled release formulation for use with a variety of drugs or hormones are formed in microspherical form. The drug or hormone, e.g. bovine somatropine, is suspended in a polymer matrix. The...
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5407686 |
Sustained release composition for oral administration of active ingredient
A sustained release tablet adapted to provide an initial immediate release of an active agent, a period of no release of the active agent, followed by a substantially constant, rate of release of...
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5378474 |
Sustained release pharmaceutical composition
The present invention relates to a pharmaceutical pellet composition having a core element including at least one highly soluble active ingredient and a core coating which is partially soluble at a...
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5370880 |
Pharmaceutical formulations containing acrivastine
The invention relates to a controlled release pharmaceutical formulation for oral administration which comprises discrete units comprising acrivastine or a salt thereof coated with a mixture...
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5364636 |
Inhibitor of absorption of digestion product of food and drink
A drug for preventing the absorption of food materials dissolved during digestion, a drug for preventing obesity, a drug for treating hyperlipemia, a drug for treating diabetes mellitus, and a drug...
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5328942 |
Seed film compositions
Film-forming compositions for coating objects, such as seeds, are characterized by a cellulosic polymer, and a polyalkylene oxide polymer. The compositions may also include a glycol, microbial...
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5326572 |
Freeze-dried polymer dispersions and the use thereof in preparing sustained-release pharmaceutical compositions
Freeze-dried polymer latices, which can be reconstituted in water to give aqueous polymer dispersions having high polymer solids content, are described. The reconstituted polymer dispersions are...
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5320855 |
Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
Chewable medicament tablets are made from coated rotogranules of a medicament wherein the rotogranules are formed from a granulation mixture of medicament, e.g. ibuprofen, polyvinylpyrrolidone,...
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5316772 |
Bilayered oral pharmaceutical composition with pH dependent release
An oral pharmaceutical composition comprises a core containing a drug, a first inner layer coating on the core which contains a drug, and a second inner layer coating on the first inner layer...
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5298262 |
Use of ionic cloud point modifiers to prevent particle aggregation during sterilization
This invention discloses a composition comprised of nanoparticles having a surface modifier adsorbed on the surface thereof and an anionic or cationic surfactant as a cloud point modifier...
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5294448 |
Delayed release formulations
Delayed release compositions comprising an active compound and amorphous amylose and having an outer coating comprising a film forming cellulose or acrylic polymer material, for example glassy...
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5292518 |
Prolonged-release drug tablet formulations
A prolonged-release unit dosage formulation or pharmaceutical composition, preferably in tablet form, is described. The composition consists essentially of a gel-forming dietary fiber, a...
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5288500 |
Oral composition containing particles comprising an active substance
An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance,...
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5275825 |
Compressed-molded preparations
Compressed molded preparations are disclosed. In the preparation coated granules of a pharmaceutical composition are compressed and molded together with non-coated component(s) containing 10% or...
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5270055 |
Solid pharmaceutical sustained-release form
A solid pharmaceutical sustained-release form, consisting of a core containing the active compound as well as conventional pharmaceutical auxiliaries, a coat which delays the release of the active...
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5270056 |
Particle having a dyed coke indicator and a pharmaceutical coating for parenteral administration of the pharmaceutical
A particle containing a liquid-soluble active substance for release outside a human or animal body, said particle comprising a core with a coating thereon, said coating comprising a liquid soluble...
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5268182 |
Sustained-release drug dosage units of terazosin
A sustained-release coating composition is described that contains an ethylcellulose and/or a methacrylic methylester together with a plasticizer and a detackifying agent. Sized drug granules are...
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5254347 |
Controlled release pharmaceutical preparation and method for producing the same
Disclosed is a controlled release pharmaceutical preparation, comprising a core containing a pharmaceutically active ingredient, and a porous film of a hydrophobic polymeric substance or a...
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5252337 |
Controlled release calcium channel blocker microcapsules
A controlled release formulation of a calcium channel blocker for oral administration contains non-pareil seeds loaded with a calcium channel blocker, particularly diltiazem, nifedipine, or...
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5238686 |
Sustained-release pharmaceutical preparation
A sustained-release pharmaceutical preparation comprising an admixture of uncoated and/or single walled water soluble drug, such as aspirin, and dual walled coated drug. The dual wall structure has...
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5234691 |
Sustained-release prepararation of basic medical agent hydrochloride
A preparation obtained by coating granules containing both a basic medical agent hydrochloride (e.g. allotinolol hydrochloride) and a polyanion the particles of which are present in the form of a...
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5232706 |
Oral pharmaceutical preparation containing omeprazol
The preparation comprises a nucleus formed by a mixture of omeprazol or an alkali salt of omeprazol with a first basic compound; the nucleus has two coatings, the first of which is formed by one or...
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5225206 |
Sustained-release pranoprofen preparation
A sustained-release pranoprofen preparation is disclosed. The preparation comprises an effective amount of pranoprofen and one or more sustained-release components selected from the group...
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5215757 |
Encapsulated materials
This invention relates to polymeric liquid crystals prepared from a polysaccharide and a solvent, preferably water, which are used to deliver nutrients, perfumes, flavors, drugs and other...
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5213811 |
Oral sustained-release drug compositions
Sugar or sugar/starch beads coated with a first coating of a drug, for example 1,2-dihydro-6-(lower alkyl)-2-oxo-5-(4-pyridinyl)-nicotinonitrile (milrinone), hydroxypropyl methylcellulose or...
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5204121 |
Medicaments having controlled release of the active compound
Controlled release medicament pellets comprising a) a core which contains as active ingredient a compound of the formula ##STR1## or a compound from the group of...
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5196203 |
Theophylline dosage form
A pH-dependent sustained release pharmaceutical pellet composition and a method of administering the same to a patient at a predetermined dosage and interval, said pellet composition comprising: a...
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5192552 |
Process for preparing microcapsules providing the rapid release of a drug as active ingredient
The invention relates to the preparation of microcapsules ensuring direct tablet compression of a drug and rapid release of the drug as active ingredient from the tablets, which comprises...
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5188841 |
Sustained release pharmaceutical formulations
The invention provides a sustained release formulation of ketoprofen comprising granules each of which comprises a core comprising ketoprofen and microcrystalline cellulose and a coating comprising...
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5186930 |
Sustained release oral suspensions
Stable sustained release wax- and polymer-coated drug-ion exchange resin complexes especially useful in preparing oral suspensions are disclosed.
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5167964 |
Semi-enteric drug delivery systems and methods for preparing same
The present invention pertains to semi-enteric drug delivery systems which comprise (a) an inert core, (b) a first coating layer over the core comprising a medicament, and (c) a second coating...
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5158777 |
Captopril formulation providing increased duration of activity
A formulation comprising captopril within an enteric or delayed release coated pH stable core combined with additional captopril that is available for immediate release following administration.
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5152995 |
Stable antibiotic ester feed compositions
Acid-sensitive antibiotic esters for oral administration to livestock are stabilized by incorporation in premix formulations comprising a carrier, a base, a protective coating, and optionally a...
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5151264 |
Particulate vector useful in particular for the transport of molecules with biological activity and process for its preparation
A particulate carrier, including a hydrophilic, non-liquid core, a first layer or ring of lipid nature bonded to the core by covalent bonds and a second layer or outer shell of amphiphilic...
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5145684 |
Surface modified drug nanoparticles
Dispersible particles consisting essentially of a crystalline drug substance having a surface modifier adsorbed on the surface thereof in an amount sufficient to maintain an effective average...
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5137733 |
Controlled release pharmaceutical preparation
A controlled release pharmaceutical preparation comprising a core containing a medicinal compound and a coating layer containing a water-repellent salt and a water-insoluble and slightly...
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5112621 |
Sustained release pharmaceutical composition of diltiazem
A sustained-release pharmaceutical composition which comprises microparticles comprising an active principle, said microparticles being coated with a coating mixture comprising ethyl cellulose and...
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5098718 |
Enzymatically degradable coating compositions for feed additives intended for ruminants
Enzymatically degradable compositions for the coating of feed additives intended for ruminants, including zein, at least one hydrophobic substance, optionally at least one non-water-soluble polymer...
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5091175 |
Pharmaceutical composition containing bile acid sequestrant enclosed in a size-exclusion membrane
A pharmaceutical composition useful for treating hypercholesterolemia comprising a bile acid sequestrant resin such as cholestyramine and cholestipol maintained in a semipermeable water-insoluble...
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5089271 |
Stabilized antibiotic compositions for animal feeding
Stabilized antibiotic composition for animal feeds which provide for improved recovery of the antibiotic from the animal feed. The compositions contain the antibiotic in a coated form. In a...
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5084287 |
Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat
A pharmaceutical preparation comprising drug micropellets containing a drug coated on a core material wherein each pellet ranges in size from about 70 microns to 750 microns and wherein each...
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5084278 |
Taste-masked pharmaceutical compositions
In accordance with the present invention, these and other objects are achieved by a pharmaceutical composition comprised of 1) a pharmaceutical core which is further comprised of a pharmaceutically...
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5082669 |
Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked
A rapid-releasing oral particle pharmaceutical preparation with its unpleasant taste masked comprising a core and a film layer coating the core, the core at least containing a drug having an...
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5073377 |
Method of preparing oral dosage forms with a granulating composition
The invention involves a granulating composition composed of an aqueous solution of magnesium sulfate heptahydrate and sodium hexametaphosphate. This composition can be used to prepare granules of...
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5051305 |
Stabilized perfume-containing microcapsules and method of preparing the same
Rupturable microcapsules made up of very small droplets or globules of perfume oil encapsulated with an inert polymeric wall are stabilized by providing ethyl cellulose in the perfume oil. This...
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5019399 |
Granular product (IV)
The present invention relates to a granular product, whereby it consists of a solid product, which has been provided with a coating of a water-soluble material, which has been provided as a melt,...
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