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5453280 Production of pellets composed of an ephedrine derivative  
A process for producing pellets which are markedly spherical and have a particle size in the range from 0.1 to 4 mm and an apparent density above 0.5 g/cm 3 , and which are composed of 90-100% by...
5449521 Supported drugs with increased dissolution rate, and a process for their preparation  
Supported drugs with an increased dissolution rate, prepared by a process comprising mixing the drug with the support material under dry conditions, co-grinding the mixture in a mill with its...
5445826 Delivery system containing a gel-forming dietary fiber and a drug  
A prolonged-release unit dosage formulation or pharmaceutical composition, preferably in tablet form, is described. The composition consists essentially of a gel-forming fiber, preferably...
5445831 Psyllium-containing products  
Psyllium husk comprising particle sizes distributed such that: less than about 15% is larger than about 80 mesh, at least about 45% is within the range of from about 80 mesh to about 200 mesh, and...
5436004 Administration of cholesterol reductase to humans  
Cholesterol reductase is administered to humans to convert cholesterol to coprostanol in the small intestine thus decreasing the bloodstream cholesterol level.
5430021 Hydrophobic drug delivery systems  
A pharmaceutical preparation including a drug incorporated into hydrophobic particles comprised of long chain carboxylic acid or ester thereof or long chain alcohol, wherein the particles are...
5427800 Process for preparation of an extract of active ingredients in a dry adsorbable form and adsorbable form and adsorbable microgranules thus obtained  
A process for the preparation of a dry adsorbable extract of at least one active ingredient, comprising the steps of: first, preparing an extract of the active ingredient in a solvent medium...
5427935 Hybrid membrane bead and process for encapsulating materials in semi-permeable hybrid membranes  
Material such as biological material is encapsulated within a semi-permeable hybrid membrane bead by suspending the material in a medium which comprises an effective amount of a gelling inducer;...
5427779 Modification of polymer surfaces and molecular immobilization by photoreaction  
A method for modifying the surface of a solid polymer wherein the polymer surface is exposed to an aqueous solution containing a two-ring heterocyclic compound that is described in more detail...
5422121 Oral dosage unit form  
Coating agents comprising a liquid phase, a polysaccharide decomposable in the colon, such as locust bean gum or guar gum, and a film forming polymer preferably having hydrophilic groups, which...
5417982 Controlled release of drugs or hormones in biodegradable polymer microspheres  
A controlled release formulation for use with a variety of drugs or hormones are formed in microspherical form. The drug or hormone, e.g. bovine somatropine, is suspended in a polymer matrix. The...
5397576 Spray triturated micronutrient compositions  
Substantially dried free flowing micronutrient compositions having up to 15% by weight of a micronutrient, a binder, and a densifying agent are produced according to the invention. The process for...
5393333 Film-forming product for coating solid forms, process for its manufacture and products coated with this film-forming product  
The present invention relates to a film-forming product for coating solid forms, to a process for the manufacture of this film-forming product and to products coated with this film-forming product....
5393525 Contrast medium comprising superparamagnetic or ferromagnetic particles capable of increasing viscosity after administration  
There is provided a contrast medium composition comprising magnetically responsive particles and a physiologically tolerable, incompletely hydrated viscosity enhancing agent.
5389372 Stable formulation of plant extract  
A stable formulation of Sennosides with increased shelf-life and good solubility comprising a granulate containing Senna extract concentrate and, for each part by weight of Senna extract...
5385739 Stable compositions of gastroprotected omerprazole microgranules and process for the production thereof  
The present invention relates to a stable formulation of omeprazole microgranules containing a neutral core consisting of sugar and starch, characterized in that it contains an active layer...
5378474 Sustained release pharmaceutical composition  
The present invention relates to a pharmaceutical pellet composition having a core element including at least one highly soluble active ingredient and a core coating which is partially soluble at a...
5376362 Antiperspirant-deodorant cosmetic products  
This invention provides a homogeneous antiperspirant cosmetic stick or roll-on product containing a deodorant ingredient which consists of particles that contain multiple fine crystallites of a...
5370880 Pharmaceutical formulations containing acrivastine  
The invention relates to a controlled release pharmaceutical formulation for oral administration which comprises discrete units comprising acrivastine or a salt thereof coated with a mixture...
5364636 Inhibitor of absorption of digestion product of food and drink  
A drug for preventing the absorption of food materials dissolved during digestion, a drug for preventing obesity, a drug for treating hyperlipemia, a drug for treating diabetes mellitus, and a drug...
5364647 Powdered preparations of surface active alkylglycosides  
Powder-form preparations of surface-active alkyl glycosides contain 5 to 65% by weight of a surface-active alkyl glycoside and 35 to 95% by weight of an inert inorganic support. They are produced...
5362425 Organic oil spray-drying techniques  
In this invention, the purpose is to provide a shelf-stable spray-dried powder embodying a desired organic oil, such as a flavorant, for example. First, hydroxylated lecithin is subject to a...
5360607 Method for production and use of pathogenic fungal preparation for pest control  
The present invention provides a process, formulations, and method of using novel biopesticides comprised of a prilled formulation comprising a carrier and a pathogenic fungal mycelium.
5354559 Encapsulation with starch hydrolyzate acid esters  
Improved encapsulated products comprising a matrix of a starch hydrolyzate acid ester having a water-insoluble material encapsulated therein. In preferred embodiments, a reducing sugar is employed...
5352461 Self assembling diketopiperazine drug delivery system  
Drug delivery systems have been developed based on the formation of diketopiperazine (or analogs) microparticles. In the preferred embodiment the microparticle is stable at low pH and disintegrates...
5346702 Use of non-ionic cloud point modifiers to minimize nanoparticle aggregation during sterilization  
This invention discloses a composition comprised of nanoparticles having a surface modifier adsorbed on the surface thereof and a non-ionic cloud point modifier associated therewith, which cloud...
5336507 Use of charged phospholipids to reduce nanoparticle aggregation  
This invention discloses a composition comprised of nanoparticles having a non-ionic surfactant as a surface modifier adsorbed on the surface thereof and a charged phospholipid as a cloud point...
5334394 Human immunodeficiency virus decoy  
A biologically active composition made up of core particles having diameters of less than about 1000 nanometers which are coated with a layer which is designed to allow attachment of biologically...
5306507 Process and composition containing pamabrom and pyrilamine maleate  
A product and process for preparing a pharmaceutical composition for forming tablets, the composition containing pamabrom and pyrilamine maleate. In preferred embodiments, the composition also...
5306506 Pharmaceutical composition for rapid suspension in water  
The invention provides a solid pharmaceutical composition for addition to water to produce a suspension of a drug comprising (a) a drug which is substantially water-insoluble or microencapsulated;...
5302399 Slow-releasing pharmaceuticals prepared with alginic acid  
A slow-releasing pharmaceutical easily prepared with alginic acid gel beads as a slow releasing carrier, and a basic medicament such as a beta-blocking agent or a calcium antagonistic agent...
5294448 Delayed release formulations  
Delayed release compositions comprising an active compound and amorphous amylose and having an outer coating comprising a film forming cellulose or acrylic polymer material, for example glassy...
5294446 Composition and method of promoting hard tissue healing  
Osteoprogenitor cells encapsulated in alginate and alternatively, additionally encapsulated in poly-L-lysine and/or agarose promote regeneration of bone at the site of implantation. The present...
5288500 Oral composition containing particles comprising an active substance  
An oral composition which is adapted to be dispersed in an aqueous carrier substantially immediately prior to administration comprises a multiplicity of particles comprising an active substance,...
5286494 Medicinal agents with sustained action  
Medicinal agents are claimed exhibiting sustained release of active compound, containing a solid active ingredient, poorly soluble in water, and auxiliary agents, characterized in that the active...
5277916 Tetracycline dosage form  
A tetracycline pharmaceutical composition having a core element containing a tetracycline antibiotic and a core coating which dissolves more slowly in the stomach than in the intestine....
5271934 Encapsulated antiperspirant salts and deodorant/antiperspirants  
Microencapsulates containing antiperspirant salts, microencapsulates in conjunction with bioadhesives, and antiperspirant/deodorant compositions containing the microencapsulates of the invention.
5260304 Pharmaceutical preparation binding with gastric acid  
Granules, possibly pressed into the form of tablets, contain at least one insoluble, complexed or slightly soluble active substance in powder form which can bind or neutralize acids and which does...
5252339 Pharmaceutical compositions containing orally absorbable glycosamimoglycans  
Pharmaceutical compositions for oral use, preferably selected from capsules, tablets or sugar coated tablets, coated by an enterosoluble gastroresistant film, containing a lyophilizate consisting...
5248772 Formation of colloidal metal dispersions using aminodextrans as reductants and protective agents  
The invention related generally to the preparation of colloidal metal(O) particles having a crosslinked aminodextran coating with pendent amine groups attached thereto. The aminodextran acts as...
5227298 Method for microencapuslation of cells or tissue  
The subject invention provides a method of encapsulating viable tissue or cells within a double walled bead, the double-walled bean produced as a result of the method, as well as a method of...
5225206 Sustained-release pranoprofen preparation  
A sustained-release pranoprofen preparation is disclosed. The preparation comprises an effective amount of pranoprofen and one or more sustained-release components selected from the group...
5219575 Compositions with controlled zero-order delivery rate and method of preparing these compositions  
The present invention relates to compositions having a controlled zero-order delivery rate of the active component. The composition comprises a core or a protective layer coated with a continuous...
5219577 Biologically active composition having a nanocrystalline core  
A biologically active composition made up of core particles having diameters of less than about 1000 nanometers which are coated with a layer which is designed to allow attachment of biologically...
5217720 Coated solid medicament form having releasability in large intestine  
A coated solid medicament form suitable for oral administration having reliable releasability of the active ingredient only in the large intestine is proposed. The medicament form is prepared by...
5215757 Encapsulated materials  
This invention relates to polymeric liquid crystals prepared from a polysaccharide and a solvent, preferably water, which are used to deliver nutrients, perfumes, flavors, drugs and other...
5213810 Stable compositions for parenteral administration and method of making same  
The invention relates to certain stable microsphere compositions suitable for parenteral administration containing a fat or wax or mixture thereof; a biologically active protein, peptide or...
5213811 Oral sustained-release drug compositions  
Sugar or sugar/starch beads coated with a first coating of a drug, for example 1,2-dihydro-6-(lower alkyl)-2-oxo-5-(4-pyridinyl)-nicotinonitrile (milrinone), hydroxypropyl methylcellulose or...
5209978 Seamless soft capsule and production thereof  
A soft capsule composed of a plurality of cells coalesced to each other and filling substances encapsulated in the individual cells, the wall of at least one of the cells being formed of a material...
5204107 Slow-releasing composition of platinum-containing anticancer agent  
A slow-releasing composition of a platinum-containing anticancer agent comprising a platinum-containing anticancer agent bound to deacetylated chitin. The release of the platinum-containing...