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5914262 |
Process and apparatus for cell sorting
A method of distinguishing between microorganisms having different attributes comprises the steps of: encapsulating one or more cells within a polymeric bead; incubating the cell(s) within the bead...
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5882684 |
Lyophilized emulsion containing an active substance
The invention concerns a freeze-dried emulsion composition containing an active substance and which can be reconstituted using water to give the original emulsion, plus a method for producing the...
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5882715 |
Method of preparing an oral preparation provided on the outer side with an enteric coating, as well as an oral preparation obtained by the method
A method of preparing an oral preparation, especially in the form of hard gelatin capsules, tablets or pellets, for use by the administration of drugs or supplementary nutrients for human beings or...
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5874110 |
Entrapping additives in carbohydrate bodies
The present invention is a method of entrapping an additive within carbohydrate bodies. The additive is drawn into the internal structure as a fluid during transformation of the bodies from a...
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5871774 |
Drug units and methods for use
Medical materials for use in treating maladies in living beings, such as ulcers and other conditions of the digestive tract. In one form, a container is provided for a medication which container...
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5869094 |
Solid form of administration of isosorbide 5-mononitrate
A solid form of oral administration of isosorbide 5-mononitrate with a controlled, pH-independent release of the active substance in the gastro-intestinal tract is constituted by a pellet coated...
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5866146 |
Compositions for fair-skin
This invention provides compositions for fair-skin containing the phosphorylated polysaccharides produced by lactic acid bacteria as an effective ingredient. The phosphorylated polysaccharides are...
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5866619 |
Colonic drug delivery system
A colonic delivery system for delivering a drug to the colon is provided. The system comprises a drug in combination with a matrix, wherein the matrix comprises a saccharide-containing polymer....
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5858410 |
Pharmaceutical nanosuspensions for medicament administration as systems with increased saturation solubility and rate of solution
Provided is a drug carrier comprising particles of at least one pure active compound which is insoluble, only sparingly soluble or moderately soluble in water, aqueous media and/or organic...
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5855826 |
Matrix-double encapsulation method and a cosmetic composition containing matrix-double capsules
Disclosed herein is a double capsule for cosmetics obtained by matrix-double-encapsulation method which comprises steps of (a) first-encapsulating the fat-soluble active matrials with filming...
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5849223 |
Liquiflash particles and method of making same
The present invention is a method of making discrete particles by subjecting an organic feedstock to liquiflash conditions whereby the feedstock is transformed instantaneously from solid to...
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5843509 |
Stabilization of colloidal systems through the formation of lipid-polyssacharide complexes
Stabilization of colloidal systems through the formation of lipid-polyssacharide complexes. Development of a procedure for the preparation of colloidal systems involving a combination of two...
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5837747 |
Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
The present invention relates to a new form of biocompatible materials (e.g., lipids, polycations, polysaccharides) which are capable of undergoing free radical polymerization, e.g., by using...
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5834444 |
Hyaluronic acid and salts thereof inhibit arterial restenosis
A method is provided of preventing arterial restenosis of an animal after the arteries have been traumatized. The method comprises the administration of a therapeutically effective non-toxic amount...
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5827707 |
Method for manufacturing minimal volume capsules containing biological materials
The present invention provides methods and a device for producing minimal volume capsules containing viable cells or cellular aggregates. The methods and device use a two-phase aqueous emulsion...
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5820882 |
Biocompatible microcapsules
Biocompatible microcapsules useful for transplanting foreign material into an animal body, and the method of their production, are described, wherein the microcapsules contain an outermost layer of...
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5817340 |
Pharmaceutical compositions containing famotidine and aluminum hydroxide or magnesium hydroxide
A solid oral dosage form for the treatment of gastrointestinal disorders comprising a therapeutically effective amount of a therapeutically effective amount of guanidinothiazole compound; and a...
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5814341 |
Cosmetic compositions
A cosmetic composition is provided comprising: A) a cosmetically acceptable carrier; and B) 0.05 to 3.0% by weight, based on the weight of the total composition, of a β-1,3-glucan having a...
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5814342 |
Prolonged release microcapsules
This invention provides a microcapsule designed for zero order release of a physiologically active polypeptide over a period of at least two months, which is produced by preparing a water-in-oil...
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5807575 |
Manufacture of cross-linked amylose useful as a excipient for control release of active compounds
A process for the manufacture of a slow-release excipient consisting mainly of cross-linked amylose in the form of solid particles, for use in the preparation of tablets or pellets. A starch...
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5800805 |
Aerosol deodorant product
This invention provides a deodorant composition in a dispensing container which is pressurized with an aerosol propellant. The primary ingredients of a typical product are particulate sodium...
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5788964 |
Method for sensitization of cancer cells for killer cell mediated lysis
The invention relates to a method of sensitizing cancer cells for a killer cell mediated lysis which involves administering to a patient an effective amount of antiestrogen and killer cells either...
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5783214 |
Bio-erodible matrix for the controlled release of medicinals
A bioerodible matrix for the controlled release of medicinals including protein therapeutics is disclosed. A method for controlled drug release is also disclosed.
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5783215 |
Pharmaceutical preparation
Controlled release beads containing a core around which is a drug-containing layer e.g. a layer containing furosemid and a process for their preparation and their use in a pharmaceutical...
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5766572 |
Water-soluble carboxypolysaccharide-magnetic iron oxide complex having a small particle diameter
A water-soluble carboxypolysaccharide-magnetic iron oxide complex of small particle diameter composed of a water-soluble carboxypolysaccharide and a magnetic iron oxide having a core diameter...
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5759582 |
Controlled release of pharmaceutically active substances from coacervate microcapsules
A controlled-release pharmaceutical composition comprising a pharmaceutically active water soluble protein, peptide, glycoprotein, or mixture thereof, encapsulated in the form of microspheres by a...
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5746999 |
Magnetic particles for diagnostic purposes
Agents containing magnetic particles are suitable for use in enhancing images in diagnostic procedures, e.g., via x-ray, ultrasound or especially NMR. Preferred particles are based on metals, e.g.,...
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5739005 |
Use of polymeric films for delivery of nematode eggs and ecological evaluations
Provided is a polymer film useful in the delivery of biological agents, as well as a method for making such a polymer film. The polymer film comprises a transparent, gelled water-soluble polymer...
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5736161 |
Pharmaceutical preparation for improving the bioavailability of drugs which are difficult to absorb and a procedure for obtaining it
The preparation consists of millispheres, microspheres, nanospheres or array-type particles consisting of a nucleus of a gellable hydrocolloid onto which has been deposited a film of a cationic...
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5720974 |
Fast dissolving tablet and its production
A method of producing a fast dissolving tablet comprising compression-molding a composition comprising an active ingredient, a carbohydrate and a barely sufficient amount of water to moisten the...
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5720978 |
Encapsulated products
Improved encapsulated products comprising a matrix of a starch hydrolyzate acid ester having a water-insoluble material encapsulated therein. In preferred embodiments, a reducing sugar is employed...
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5721221 |
Lowering blood cholesterol levels using water soluble cellulose ethers
A method for reducing the cholesterol level in mammalian blood by administering a water soluble cellulose ether thereto. The cellulose ethers have a viscosity, measured as a 2% aqueous solution at...
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5714168 |
Method for increasing flowability of spray dried vitamin powders having low vitamin concentrations
The present invention relates to a method for increasing the flowability of spray dried vitamin powders having low vitamin concentrations and high concentrations of a maltodextrin carrier by...
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5707653 |
Ulcer treating composition comprising sufalcrate and antibiotic
Pharmaceutical compositions comprising an antibiotic adsorbed onto a disaccharide polysulfate-aluminum compound such as sucralfate are effective for the treatment of ulcers. The composition...
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5705270 |
Microcapsules prepared from crosslinkable polysaccharides, polycations and/or lipids and use therefor
The present invention relates to a new form of biocompatible materials (e.g., lipids, polycations, polysaccharides) which are capable of undergoing free radical polymerization, e.g., by using...
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5693343 |
Microparticle carriers of maximal uptake capacity by both M cells and non-M cells
In a solvent extraction process for preparing microspheres of a biodegrade polymer, the improvement comprising: preparing a homogenized antigen-sucrose matrix and adding a solvent to the...
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5691060 |
Utilization of a transacylation reaction between an esterified polysaccharide and a polyaminated or polyhydroxylated substance for fabricating microparticles, microparticles thus obtained, methods and compositions containing them
The invention relates to microparticles, particularly microcapsules and their fabrication method. Said microparticles, and particularly said microcapsules, are characterized in that they have a...
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5688510 |
Process for producing stable medicinal composition, and pharmaceutical preparation
A process for producing a pharmaceutical composition is disclosed. In the process, 1 part by weight of a physiologically inert powdery additive, 0.001-1 part by weight of a macromolecular additive...
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5686113 |
Microcapsules of predetermined peptide(s) specificity (ies), their preparation and uses
An aqueous core microcapsule has a capsular wall provided with a peptide(s) of pre-determined binding specificity(ies) appended to the surface, the wall being the reaction product of an anionic...
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5683722 |
Orally-administered dosage form for animals, preparation method therefor and uses thereof
A dosage form for orally administering chemical or medicinal substances such as vitamins, trace elements, amino acids, nutritive substances, vaccines, etc., to domestic or wild animals, and a...
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5674533 |
Pharmaceutical composition for the controlled release of moguisteine in a liquid suspension
Disclosed are compositions and dosage forms containing moguisteine and having controlled release properties, methods for using such compositions and dosage forms and methods for making them.
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5670171 |
Liquid-suspension controlled-release pharmaceutical composition
Disclosed is a liquid-suspension controlled-release enteric-coated pharmaceutical formulation for the administration of naproxen, comprising (a) microgranules of naproxen and an excipient; (b) four...
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5662936 |
Sugar-coated pharmaceutical dosage unit
The invention relates to sugar-coated dosage units comprising a steroid having two hydrogen atoms at position 3 of the steroid skeleton, such as desogestrel, allylestrenol, ethylestrenol, or...
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5660845 |
Solid consumer product compositions containing small particle cyclodextrin complexes
An effective amount of active/cyclodextrin complex, in the form of particles having particle sizes below about 12 microns, is incorporated into solid consumer product compositions. The complexes...
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5656308 |
Non-reducing oligosaccharide with neotrehalose structure, and its production and uses
Disclosed is a novel non-reducing oligosaccharide with neotrehalose structure represented by the general formula as shown by: ##STR1## The oligosaccharide is obtainable by exposing an aqueous...
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5656271 |
Oral vaccine comprising anti-idiotypic antibody to chlamydia glycolipid exoantigen and process
A genus specific chlamydia oral or injectable vaccine is provided which comprises an anti-idiotype antibody capable of producing in an animal an anti-idiotypic antibody or Fab fragment thereof...
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5654004 |
Oral pharmaceutical preparation releasable in the lower digestive tract
An oral pharmaceutical preparation releasable in the lower digestive tract, characterized by having a double-coated structure wherein a solid drug having a core containing an active ingredient is...
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5651990 |
Prolonged release microparticle preparation and production of the same
A novel microparticle preparation comprising microparticles of a polymer which contain a drug and are coated with a film of an agent for preventing aggregation of the microparticles is disclosed....
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5648096 |
Process for the production of microcapsules
A method for the production of microcapsules embedded with pharmaceuticals, peptides, proteins, enzymes and vaccines, which uses biodegradable solvents, and microcapsules free of toxic residual...
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5643605 |
Methods and compositions for microencapsulation of adjuvants
Methods and compositions are provided for the encapsulation of adjuvants in PLGA microspheres for use as vaccines. Mixtures of microspheres are provided which release adjuvant at desired intervals...
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