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9040080 Processing of heat-sensitive active agents  
The present disclosure relates to a method of melt processing an active agent. The method may include encapsulating an active agent in a first polymer material exhibiting a first processing...
9040089 Oral compositions of clindamycin  
A taste masked pharmaceutical composition of clindamycin, or a pharmaceutically acceptable salt(s), hydrate(s), solvate(s) and physiologically functional derivative(s) and precursors thereof,...
9040626 Nanofibers and morphology shifting micelles  
The invention discloses novel morphology shifting micelles and amphiphilic coated metal nanofibers. Methods of using and making the same are also disclosed.
9034386 Decellularized adipose tissue  
This invention provides a method for decellularizing adipose tissue, comprising subjecting the adipose tissue to one or more incubations in an enzymatic digestion solution containing one or more...
9034385 Product based on conjugated linoleic acid and a method for the manufacture thereof  
A product based on conjugated linoleic acid (CLA) comprises an inner core in which the conjugated linoleic acid is substantially concentrated as well as a coating for covering and protecting the...
9034902 Methods for treatment of attention deficit hyperactivity disorder  
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of...
9023398 Method for improving the aqueous solubility of poorly-soluble substances  
Provided is a method for increasing the solubility of a poorly-soluble substance used in pharmaceutical products, veterinary pharmaceutical products, quasi-drugs, cosmetic products, food products,...
9023389 Compositions for treatment of attention deficit hyperactivity disorder  
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of...
9023391 Stable benzimidazole formulation  
A stable composition with a benzimidazole derivative, such as Omeprazole, which does not contain a separating layer between the active compound and an enteric coating layer. Instead, the enteric...
9023399 Water-soluble anti-inflammatory cream with natural ingredients base  
A water-soluble anti-inflammatory cream is disclosed. The cream is a composition of between about 7.5% and about 30% by weight of a healing oil; between about 1% and about 6% by weight of an...
9011913 Use of functionalized magnetic nanoparticles in cancer detection and treatment  
The present invention provides methods of detecting a cancer cell in an individual, methods of grading a cancer, and methods of treating a cancer. The methods involve use of functionalized...
9011905 Low dose topiramate/phentermine composition and methods of use thereof  
A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in...
9011964 Nano-encapsulated, controlled drug manufacturing process  
A mixed dose of a nanosized drug wherein at least one portion of the mixed dose comprises a core nanosized drug encapsulated in at least one layer of a protective material having the same core...
9011906 Escalating dosing regimen for effecting weight loss and treating obesity  
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss, e.g., in the treatment of obesity and related conditions, including conditions...
9012511 Nanoparticulate cinacalcet compositions  
Described are compositions of stable nanoparticulate cinacalcet or a salt thereof, and methods of making and using them. The compositions exhibit an improved dissolution rate, improved...
9011924 Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery  
This invention relates to biphasic lipid-vesicle compositions and methods for treating cervical displasia by intravaginal delivery.
9011923 Suspension formulations  
The present invention relates to suspension formulations, especially those for delivering a pharmaceutically active agent in aerosol form using a spray or aerosol device, such as a pressurized...
9012363 Granular controlled release agrochemical compositions and process for the preparation thereof  
A granular agrochemical composition is disclosed including a granular core material having a water soluble portion with a first coating layer applied on the surface of the core material and a...
9005540 Conjugated polyelectrolyte capsules: light activated antimicrobials  
Hollow conjugated polyelectrolyte (HCPE) microcapsules contain at least one conjugated polyelectrolyte and at least one other polyelectrolyte of complementary charge and the microcapsule has a...
9005666 Process for preparing lipid nanoparticles  
A process for preparing nanocapsules with a liquid lipid core and a solid lipid shell, charged with at least one active agent. The process contains at least the steps of formulating a...
9005658 Oral preparation with controlled release  
A pharmaceutical pellet is provided, comprising a spherical core containing the active substance with a smooth surface and a coating on the core, which controls pH-independent release of the...
9005757 Metal-salen complex compound and method for producing the same  
The present invention provides a metal-salen complex compound having a controlled grain size that enables the metal-salen complex compound to exert its pharmacological effects as a medicine, at a...
8999394 Pancreatine pellets and method of producing same  
In order to prevent impairment of the pharmacological effect of pancreatine through added auxiliary substances or binding agents a pancreatine pellet consists exclusively of pancreatine.
8999721 Method and system to provide personalized pharmaceutical compositions and dosages  
Provided is a method for assessing cardiovascular risk in Metabolic Syndrome and Type 2 Diabetes patients. The method involves obtaining data from a Type 2 diabetes patient or a Metabolic Syndrome...
9000033 Composition for improving skin condition and appearance  
Disclosed is a cosmetic composition comprising prenylated isoflavonoid and a carrier, wherein the prenylated isoflavonoid is from about 0.0000001% to about 10%, preferably from 0.00001% to 1%,...
8992984 Protocells and their use for targeted delivery of multicomponent cargos to cancer cells  
Various embodiments provide materials and methods for synthesizing protocells for use in targeted delivery of cargo components to cancer cells. In one embodiment, the lipid bilayer can be fused to...
8992991 Multicomponent degradable cationic polymers  
Degradable polymers were synthesized that self-assemble with DNA to form particles that are effective for gene delivery. Small changes to polymer synthesis conditions, particle formulation...
8992973 Controlled release compositions comprising a combination of isosorbide dinitrate and hydralazine hydrochloride  
The invention relates to a controlled release composition comprising a combination of isosorbide dinitrate and hydralazine, such as hydralazine hydrochloride, that in operation delivers the drug...
8992988 Coating film, and granules and tablets each utilizing same  
A coating film comprising ethyl cellulose as a component A and an (ethyl acrylate)-(methyl methacrylate) copolymer or a plasticized vinyl acetate polymer as a component B, and having a tensile...
8993041 Taste masked active pharmaceutical powder compositions and processes for making them  
A taste masked particulate pharmaceutical formulation include a core that comprises an active pharmaceutical ingredient; at least a partial nanoparticle material layer on the core that comprises a...
8992985 Core-shell magnetic particles and related methods  
The invention provides core-shell magnetic particles comprising a magnetic core and a functional shell, methods for making same, methods of separation using same, methods for using same, and...
8986723 Oil formulations comprising cylcopropene compounds  
A composition comprising (a) a non-aqueous pourable fluid, (b) droplets dispersed in said pourable fluid (a), wherein said droplets comprise (i) a non-aqueous continuous phase that is a solid or...
8980292 Conditioner compositions with increased deposition of polyacrylate microcapsules  
A conditioner composition that increases the deposition and retention of benefit agent containing polyacrylate microcapsules onto hair. The conditioner composition is based on the combination of...
8980320 Film coating agent for solid preparation, and solid preparation using same  
A film coating agent for a solid formulation includes a water-soluble cellulose derivative, swelling clay, a cationic surfactant, and a fatty acid, wherein mass ratio of the swelling clay to the...
8980319 Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans  
Methods for producing stabilized solid dosage form pharmaceutical compositions are provided. In particular, methods for preparing protected granules containing morphinans, and solid dosage form...
8980305 Non-abusable pharmaceutical composition comprising opioids  
There is provided pharmaceutical compositions for the treatment of pain comprising a pharmacologically-effective amount of an opioid analgesic, or a pharmaceutically-acceptable salt thereof,...
8980321 Pharmaceutical compositions providing enhanced drug concentrations  
A drug in a solubility-improved form is combined with a concentration-enhancing polymer in a sufficient amount so that the combination provides substantially enhanced drug concentration in a use...
8968790 Nanoformulation of vitamin D derivatives and/or vitamin D metabolites  
A nanoformulation that includes loaded nanoparticles. Each nanoparticle includes a modified chitosan polymer encapsulating at least one vitamin D derivative, at least one vitamin D metabolite, or...
8968781 Therapeutic compositions  
The present invention provides oral formulations of poorly bioavailable and/or poorly absorbable, and/or poorly water soluble therapeutic agents. The invention features pharmaceutical composition...
8968776 Composition comprising a benzimidazole and process for its manufacture  
The invention provides new benzimidazole compositions, comprising: (a) a core containing said benzimidazole active ingredient; (b) an intermediate layer; and (c) an enteric layer; said core being...
8962030 Nanoparticles for delivery of active agents  
Milled nanoparticles comprising a biologically active agent, at least one biopolymer and a coating containing at least one coating which is a polymer or ligand are produced using milling and...
8962031 Super paramagnetic iron oxide nanoparticles with metallic coatings and a method of synthesizing the same  
The various embodiments herein provide super paramagnetic iron oxide nanoparticles (SPIONs). The SPIONs have a plurality of metallic coatings and plurality of polymeric gaps. The embodiments...
8956662 Phenylephrine pharmaceutical formulations and compositions for colonic absorption  
The invention discloses a pharmaceutical composition comprising phenylephrine or a pharmaceutically acceptable salt thereof and an erodible layer which is for oral administration wherein the...
8956661 Method of making composite particles for use in pharmaceutical compositions and composite particles and compositions thereof  
The invention relates to a method for making composite active particles for use in a pharmaceutical composition for pulmonary administration, the method comprising a milling step in which...
8956660 Production of nanoparticles, especially nanoparticle composites, from powder agglomerates  
The invention relates to a method for producing particulate composite materials. According to the method, solid inorganic or organic particle agglomerates or particle aggregates that are provided...
8951566 Process for preparing products comprising stabilised actives and compositions comprising same  
The present invention broadly relates to a process for preparing products comprising active components, and in particular biological materials, wherein the active components are stabilized. The...
8951564 Galenic form suitable for absorbing, in a specific manner, the undesirable molecules in the digestive tract  
The present invention relates to a galenic form comprising particles capable of specifically adsorbing the undesirable molecules present in the digestive tract, to the method for preparing same...
8945629 Nanoparticles for cytoplasmic drug delivery to cancer cells  
The invention is a nanoparticle that contains an anticancer drug that is released in cancer cells when administered to a subject. The nanoparticles have a core including the anticancer drug and...
8936812 Tamper-resistant oral opioid agonist formulations  
Disclosed is a substantially non-releasable form of an opioid antagonist containing the opioid antagonist combined with one or more pharmaceutically acceptable hydrophobic material(s) such that...
8932715 Precipitation stabilising compositions comprising bioactive molecule and at least one cationic and one anionic precipitation stabilizing additives  
The present invention relates to maintaining bioactive molecules in their native or substantially near-native form and preventing or reduce aggregation. In particular, the present invention...