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9034379 Processing of acylchitosan hydrogels  
An article containing N-acylchitosan is manufactured by a process comprising the steps of providing a mixture containing chitosan and/or N-acylchitosan, and extruding the mixture to form an...
9029275 Nanofiber sheet, process for producing the same, and fiber-reinforced composite material  
Provided is a nanofiber sheet that sufficiently refined by fibrillation and has high crystallinity of cellulose fiber and can realize a fiber-reinforced composite material exhibiting high...
9028872 Gelled composite  
The invention relates to composites comprising a polysaccharide gelled within pores of a foam, methods of preparation, and uses thereof, for example, in biomedical applications such as cell culture...
9028861 Method and composition to reduce diarrhea in a companion animal  
Compositions (including pharmaceutical compositions, foods, supplements, toys and treats) comprising a microbial exopolysaccharide are provided as well as methods for preventing or reducing...
9011894 Sterile hyaluronic acid polymer compositions and related methods  
The present application provides sterile hyaluronic polymer compositions than are useful, e.g., as medical devices, biomedical adhesives, and sealants. Generally, provided are sterile dry...
9011920 Transport-mediating colloidal pharmaceutical compounds  
The invention relates to transport mediator-bonded colloids comprising pharmaceutical substances or fluorescence markers, to a method for the production thereof, and to a pharmaceutical preparation...
9005597 Formulation for treatment of vaginal dryness  
The present invention is directed to a composition for treating vaginal dryness and lack of lubrication comprising: a poloxamer component; a phospholipid component; an optional oil component; and a...
8999945 Methods, compositions and systems for local delivery of drugs  
Implantable medical device eluting drug locally and in a prolonged fashion are provided.
8999377 System for forming a biocompatible foam using polymerizable alpha(1-4)glucopyranose polymers and gas-producing component  
Biocompatible foams having excellent physical and chemical properties are described. The biocompatible foams can be formed in situ or applied as a pre-formed foam for the treatment of tissue. The...
8999391 Methyl ethyl hydroxyethyl cellulose for personal care applications  
A thickening system for personal care formulations including methyl ethyl hydroxyethyl cellulose provides efficient thickening power in applications areas such as shampoo and styling gels. In...
8986735 Solid dosage form containing a taste masked active agent  
A solid dosage form containing a taste masked active agent is provided. The solid dosage form may be provided as a water soluble film that is disintegrable in the oral cavity to deliver and release...
8974827 Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer  
A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, a poorly aqueous soluble non-ionizable cellulosic polymer, and a poorly aqueous soluble polymeric...
8968785 Surgical compositions  
The present disclosure relates to multi-component hydrogels. The hydrogels may include a natural component having nucleophilic functional groups as well as an electrophilic component. In...
8968784 Method for preparing hydro/organo gelators from disaccharide sugars by biocatalysis and their use in enzyme-triggered drug delivery  
A method for preparing hydro/organo gelators from disaccharide sugars by biocatalysis and their use in enzyme-triggered drug delivery. Controlled delivery of an anti-inflammatory, chemopreventive...
8968773 Silicone film former for delivery of actives  
The invention provides: a cross-linkable therapeutic composition comprising a) a saccharide-siloxane copolymer; b) a crosslinking agent; c) one or more active/inactive ingredients; and d)...
8952057 Compositions for anorectal use and methods for treating anorectal disorders  
Compositions containing polymetal complexes are useful in treating anorectal disorders.
8945619 Shell-and-core dosage form approaching zero-order drug release  
Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core by...
8945625 Regulated delivery systems for inner ear drug application and uses thereof  
The invention relates to a controlled release delivery compositions and methods of using them for pathologies associated with Otorhinolaryngology and Head and Neck. Specifically, the invention...
8945608 Composition and method to alleviate joint pain  
Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found with krill oil and/or marine oil in combination with other...
8945624 Photoinitiated tissue filler  
Visible light-activated polymer cosmetic filler preparations useful in a variety of applications are provided. In some embodiments, the photo-activated polymer composition comprises a conventional...
8940675 Cleansing composition and a wet wipe comprising the same  
The present disclosure includes cleansing compositions for removing soils from surfaces. Tee cleansing composition may be loaded ones a substrate to form a wet wipe. The cleansing composition may...
8940344 Capsule clusters for oral consumption  
Provided are oral products that provide engaging and flavorful experiences to a user. The oral product includes a plurality of capsules, a powdered component, a viscous component and a binder that...
8940888 Hydrazido derivatives of hyaluronic acid  
Disclosed are chemically modified hyaluronic acid (HA) derivatives containing hydrazido groups directly linked to the glucuronic acid residues of HA. Said hydrazido groups are used to obtain...
8936805 Bone regeneration using biodegradable polymeric nanocomposite materials and applications of the same  
A structure of, and a method of producing, a biocompatible structure for bone and tissue regeneration are disclosed. The method includes dissolving a polyurethane polymer in methanol, adding...
8932616 Hydrophobic polysaccharides with silyl ether linkages having enhanced degradation and medical articles made therefrom  
Hydrophobic α(1→4)glucopyranose polymers with enhanced degradation properties are described. Between the α(1→4)glucopyranose polymeric portion and the hydrophobic portion exists a linker porti...
8932633 Polysaccharide microparticles containing biological agents: their preparation and applications  
A method of preparing polysaccharide glassy microparticles which are less than 10 μum in diameter and contain structurally delicate agents, such as proteins, peptides, gene materials, vaccines, ...
8927018 Immobilized metallic nanoparticles as unique materials for therapeutic and biosensor applications  
The present invention relates to compositions and methods by which surface modification techniques can be used to modify wide range polymeric or metal substrates using metal nanoparticles.
8927028 Pharmaceutical composition containing coated, floating particles  
A dosage form exhibiting delayed transit time through the GI tract. The dosage form comprises a plurality of buoyant particles, each comprising an inner drug-containing core, an intermediate layer...
8920842 Temperature controlled and pH dependent self gelling biopolymeric aqueous solution  
The present invention relates a biopolymeric liquid aqueous composition for producing self-gelling systems and gels, which comprises: an acidic water-based medium, 0.1 to 10% by weight of a...
8916182 Composition comprising oligogalacturonans and polycationic saccharides  
A ‘bioactive’ composition that has one or more oligogalacturonans ((1→4)-α-D-galacturonan) or any other oligosaccharides (oligoguluronans) that may present an ‘egg box’ conformation, this confo...
8911816 Coating composition and use thereof  
The present invention relates to a new coating composition and especially a new coating composition to be used with a specific coating device for providing an even, thin and enclosing coating on...
8906362 Tissue engineered meniscus scaffolds and methods of use  
Provided herein are methods of producing a meniscus scaffold to remove material and increase the pore size and porosity therein. In some embodiments, methods include seeding the tissue with...
8900623 Sticky soft gel for treating poultry  
The present invention is directed to a composition, kit and method for delivering a soft flowable gel to a flock of poultry in barns, but can also be used in hatcheries or free range farms, for...
8900868 Hydrogel-based vascular lineage cell growth media and uses thereof  
A medium for growing vascular lineage cells is described. The vascular lineage cell growth medium includes an oligosaccharide-based hydrogel and a growth factor that promotes vascularization by...
8895065 Single unit oral dose pharmaceutical composition comprising levodopa, carbidopa and entacapone or salts thereof  
There is provided a single unit oral dose pharmaceutical composition comprising a) levodopa or salts thereof from about 50 mg to about 300 mg in extended release form, b) carbidopa or salts thereof...
8883184 Methods and compositions for regenerating connective tissue  
Connective tissue regenerative compositions and methods of repairing and regenerating connective tissue using such compositions are provided. The compositions generally comprise a bioactive...
8877243 Cross-linked polysaccharide composition  
A process for making cross-linked polysaccharide gels, particularly cross-linked hyaluronic acid gels, under basic conditions. The resulting gels possess improved degradation characteristics, and...
8871263 Manufacture of tablet in a die utilizing radiofrequency energy and meltable binder  
The present invention features a process for making a tablet by (i) compacting a powder blend in a die to form a tablet shape, wherein the powder blend contains a pharmaceutically active agent and...
8859523 Crosslinked compounds and methods of making and using thereof  
Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) the oxidative coupling of two or more thiol compounds...
8858997 Formulations and methods for lyophilization and lyophilates provided thereby  
The present invention provides compositions, methods for lyophilizing compounds and making pharmaceutical compositions, and kits providing solutions and lyophilized formulations of compounds. The...
8858999 Method to produce hyaluronic acid functionalized derivatives and formation of hydrogels thereof  
In this invention a two steps procedure is described useful to insert functional groups to the hyaluronic acid (HA), through the formation, in organic solvent, of a particular active group on...
8859716 Degradable thiol-ene polymers  
A thiol-ene polymeric material is disclosed. The material is produced by the photopolymerization of reactants having thiol and olefin moieties. The material can incorporate encapsulated components,...
8853361 Preparation, for use, in particular, for tissue augmentation and healing  
The invention relates to a sterile preparation which can be implanted on or in organic tissues, comprising: a natural or modified globin material which is insoluble at physiological pH and/or a...
8846095 Dextran-based polymer tissue adhesive for medical use  
A tissue adhesive formed by reacting an aminodextran containing primary amine groups with an oxidized dextran containing aldehyde groups is described. The dextran-based polymer tissue adhesive is...
8846103 Exogenously triggered controlled release materials and uses thereof  
The disclosure provides cross-linked materials that include multivalent cross-linking agents that bind an exogenous target molecule; and conjugates that include two or more separate affinity...
8846094 Peripherally administered viscous formulations  
Viscous formulations and methods of using such compositions, useful for intramuscular and intra-articular injection are provided to treat peripheral conditions. Such compositions can include...
8834937 Bone filling material comprising sintered titanium dioxide and dextrin and method for reconstructing bone defects using the same  
A bone filling material comprising sintered titanium dioxide and dextrin and a method for reconstructing bone defects which comprises filling the bone defects in an animal with the bone filling...
8834889 Antigen presenting composition and use thereof  
An antigen presenting composition comprising a plurality of 2-component MHC class I complexes and a carrier is described. A method for activating a group of antigen-specific CD8+ T cells comprising...
8833378 Process for preparing snuff composition  
A method for the preparation of a nicotine-cellulose combination, the method comprising simultaneous loading of the nicotine on the cellulose and agglomeration of the particles so as to obtain a...
8821936 Solid pharmaceutical formulation  
This invention provides a solid pharmaceutical formulation having high physical strength and further having excellent drug release properties and digestibility of excipients when administered,...