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8859523 Crosslinked compounds and methods of making and using thereof  
Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) the oxidative coupling of two or more thiol compounds...
8858997 Formulations and methods for lyophilization and lyophilates provided thereby  
The present invention provides compositions, methods for lyophilizing compounds and making pharmaceutical compositions, and kits providing solutions and lyophilized formulations of compounds. The...
8858999 Method to produce hyaluronic acid functionalized derivatives and formation of hydrogels thereof  
In this invention a two steps procedure is described useful to insert functional groups to the hyaluronic acid (HA), through the formation, in organic solvent, of a particular active group on...
8859716 Degradable thiol-ene polymers  
A thiol-ene polymeric material is disclosed. The material is produced by the photopolymerization of reactants having thiol and olefin moieties. The material can incorporate encapsulated components,...
8853361 Preparation, for use, in particular, for tissue augmentation and healing  
The invention relates to a sterile preparation which can be implanted on or in organic tissues, comprising: a natural or modified globin material which is insoluble at physiological pH and/or a...
8846095 Dextran-based polymer tissue adhesive for medical use  
A tissue adhesive formed by reacting an aminodextran containing primary amine groups with an oxidized dextran containing aldehyde groups is described. The dextran-based polymer tissue adhesive is...
8846103 Exogenously triggered controlled release materials and uses thereof  
The disclosure provides cross-linked materials that include multivalent cross-linking agents that bind an exogenous target molecule; and conjugates that include two or more separate affinity...
8846094 Peripherally administered viscous formulations  
Viscous formulations and methods of using such compositions, useful for intramuscular and intra-articular injection are provided to treat peripheral conditions. Such compositions can include...
8834937 Bone filling material comprising sintered titanium dioxide and dextrin and method for reconstructing bone defects using the same  
A bone filling material comprising sintered titanium dioxide and dextrin and a method for reconstructing bone defects which comprises filling the bone defects in an animal with the bone filling...
8834889 Antigen presenting composition and use thereof  
An antigen presenting composition comprising a plurality of 2-component MHC class I complexes and a carrier is described. A method for activating a group of antigen-specific CD8+ T cells comprising...
8833378 Process for preparing snuff composition  
A method for the preparation of a nicotine-cellulose combination, the method comprising simultaneous loading of the nicotine on the cellulose and agglomeration of the particles so as to obtain a...
8821936 Solid pharmaceutical formulation  
This invention provides a solid pharmaceutical formulation having high physical strength and further having excellent drug release properties and digestibility of excipients when administered,...
8821932 Pharmaceutical compositions  
A process for the production of a composition comprising a water-insoluble statin which comprises the steps of: a) providing a mixture comprising: i) a water-insoluble statin ii) a water soluble...
8822676 Hyaluronic acid-based gels including lidocaine  
Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic...
8820331 Smoking device incorporating a breakable capsule, breakable capsule and process for manufacturing said capsule  
A smoking device includes a recipient or able to receive burning (i.e., burnable) products, preferably tobacco, and a filter element connected to the recipient, wherein the filter includes at least...
8821933 Polymers and hydrogels  
Methods and compositions related polymers and hydrogels. In some cases to biodegradable hydrogels for use in medical applications are disclosed. The polymers and hydrogels may be produced from...
8795715 Compositions of fat-soluble substances  
The invention relates to novel powderous, water-soluble compositions of fat-soluble substances and aqueous solutions or emulsions thereof, wherein the fat-soluble substance(s) are encapsulated as...
8796341 Pharmaceutical compositions providing enhanced drug concentrations  
A drug in a solubility-improved form is combined with a concentration-enhancing polymer in a sufficient amount so that the combination provides substantially enhanced drug concentration in a use...
8790695 Medicinal carriers, and preparation method and uses thereof  
A medicinal carrier is provided. The medicinal carrier comprises a first component, which is a biocompatible polymer with an amino group (—NH2); a saccharide; and a second component which is a b...
8790702 Modified hyaluronic acid polymer compositions and related methods  
The present application provides compositions comprising hyaluronic acid having low levels of functional group modification, mixtures formed by controlled reaction of such lightly modified...
8790631 Use of biocompatible polymers for the preparation of a composition or a medical device  
The invention relates to a biocompatible polymer having general formula (I) AaXxYy, wherein: A denotes a monomer; X denotes an RCOOR′ group; Y denotes an O or N-sulphonate group which is fixed to A...
8790701 Poly-α(1→4)glucopyranose-based matrices with hydrazide crosslinking  
The present invention provides biocompatible, biodegradable matrices formed from poly-α(1→4)glucopyranose and reactive hydrazide groups. The matrices can be used for various applications in the bo...
8784893 Polymer formulations for delivery of bioactive agents  
Disclosed in the present application are compositions comprising a bioresorbable polymer matrix and a bio active agent, wherein the bioactive agent is dispersed within polymer matrix as a solid....
8785418 Lyophilization cakes of proteasome inhibitors  
Lyophilized cakes of proteasome inhibitors are described, as well as methods for their production and use.
8778399 In situ, liquid-activated film coated tablets and a process for making the same  
Tablets and other objects are film coated by including in the tablet a film-forming polymer that is activated upon contact with an activating amount of liquid. The film-forming polymer, e.g., a...
8778909 Method of applying an injectable filler  
Methods for applying injectable fillers are provided. In some embodiments, the methods can extend effectiveness of the injectable filler. In some embodiments, the methods can provide for an...
8778369 Barrier film-forming compositions and methods of use  
Long-lasting persistent, uniform, film-forming skin protecting compositions provide long-lasting persistent barrier films when applied to skin. The compositions have particular utility as barrier...
8758819 Cosmetic compositions for the treatment of skin and methods thereof  
A cosmetic composition comprising at least one compound selected from bioactive/biocompatible microparticulates such as bioactive glass or bioactive ceramics, and an intradermal delivery vehicle...
8758729 Oral compositions containing polyguanidinium compounds and methods of manufacture and use thereof  
The invention describes the modification of polyamine-based materials to form polyguanidine compounds that are useful for their antimicrobial, anticaries, and muccoadhesive properties. The present...
8753705 Mineral-bound starch compositions and methods of making the same  
Mineral-bound starch products are provided for enhanced absorption of nutrient minerals. The mineral-bound starch products are prepared by binding biologically active minerals to phosphorylated...
8748476 Darifenacin for use in the treatment of urgency induced by overactive bladder  
The invention provides the use of darifenacin, or a pharmaceutically acceptable derivative thereof, in the manufacture of a medicament for the reduction of urgency in patients suffering from...
8747893 Capsule which disintegrates specifically in the large intestine  
The present invention is to obtain capsules which do not disintegrate in stomach and intestine after orally administrating them and which disintegrate specifically in large intestine. The present...
8741331 Hydrogel compositions with an erodible backing member  
A composition is provided, wherein the composition comprises a water-swellable, water-insoluble polymer, a blend of a hydrophilic polymer with a complementary oligomer capable of hydrogen or...
8741269 Non-aqueous dentifrice composition with bioacceptable and bioactive glass and methods of use and manufacture thereof  
The invention encompasses non-aqueous dentifrice compositions containing a bioacceptable and bioactive glass with improved mouth-feel, foam, and product stability. More particularly, the invention...
8741347 Method for forming cyclodextrin polymer and lipophilic compound emulsions, resulting emulsions, and compositions including said emulsions  
The present invention relates to a method for preparing a cyclodextrin polymer and/or a hydrophilic polymer emulsion having cyclodextrins as well as lipophilic compounds, the emulsions having a...
8741346 Method for the preparation of molecular complexes  
The invention relates to a method for the preparation of soluble molecular complexes, comprising one or more active substances which are poorly-soluble in an aqueous medium, included within one or...
8741645 Test kit comprising a culture instrument with a cell pattern and a gel suitable to embed cell pattern  
The present invention provides a method for performing a biological test under conditions in which an artificially prepared cell pattern with initial position coordinates that can be determined is...
8728504 Process for solubilizing hydrophobic active ingredients in aqueous medium  
A process for solubilizing hydrophobic active ingredients in aqueous medium, which comprises using, as an assistant, at least one hyperbranched polymer (A) which is obtainable by reacting at least...
8728499 Dendritic macroporous hydrogels prepared by crystal templating  
The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture...
8728524 Biomaterials consisting of sulphated hyaluronic acid and gellan to be used in the prevention of spinal adhesions  
New biomaterials consisting of a combination of sulphated hyaluronic acid and gellan (as well as gellan that has not been associated with other polymers), to be used as a highly effective barrier...
8722066 Devices and methods for weight control and weight loss  
The present invention provides, compositions, devices, and methods for affecting, among other things, weight loss and/or weight control, by sequestering nutrients or other compounds such as toxins...
8722749 Method for producing hydrocolloid foams  
A method for producing foams, such as sponges, from hydrocolloids is described. A solid or semi-solid gel is formed by dissolving polymeric material in an aqueous solvent. The gel formed is allowed...
8715733 Enhanced adipose tissue  
An enhanced adipose tissue containing native adipose tissue and a concentrated amount of an active agent derived from adipose tissue, wherein the enhanced adipose tissue is preferably injected into...
8715719 Stable chitosan hemostatic implant and methods of manufacture  
A method of preparing a stable chitosan hemostatic implant including preparing a lyophilizable solution of chitosan polymers and freezing the solution to obtain a frozen chitosan composition. The...
8716213 Liquid detergent composition comprising an external structuring system comprising a bacterial cellulose network  
A structured liquid detergent composition in the form of a liquid matrix made up of an external structuring system of a bacterial cellulose network; water; and surfactant system including an...
8703171 Method for easing human childbirth using a lubricant composition  
The present invention relates to a method of easing childbirth using a composition having a lubricant effect for use in particular during human vaginal delivery. The methods comprise applying a...
8703924 Chitosan composition  
This invention relates to a cross-linkable chitosan composition comprising chitosan having a degree of deacetylation between 30 and 75%, wherein the chitosan is randomly deacetylated, and a...
8703691 Liquid detergent composition comprising an external structuring system comprising a bacterial cellulose network  
A structured liquid detergent composition in the form of a liquid matrix made up of an external structuring system of a bacterial cellulose network; water; and surfactant system including an...
8703198 Water-based personal moisturizers and lubricants, in particular vaginal lubricants, and uses thereof  
There is a need for water-based sperm- and egg-friendly vaginal lubricant. We describe novel water-based nature-friendly personal moisturizers and lubricants that relive vaginal dryness. In...
8703199 Pharmaceutical compositions of adsorbates of amorphous drug  
Pharmaceutical compositions comprise a low-solubility drug adsorbed onto a high surface area substrate to form an adsorbate. The compositions in some embodiments include a concentration-enhancing...