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7618651 |
Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
The present invention relates to pharmaceutical compositions in the form of a gel for controlled- or sustained-release of a pharmaceutically active agent and to methods for treating or preventing...
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7612029 |
Controlled release using gels in a melamine foam
A substrate comprising a nonwoven layer containing an ionically crosslinked polymer can be used to control the release of active ingredients. The substrate can be a melamine foam and contain a...
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7592418 |
Biocompatible crosslinked polymers with visualization agents
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having...
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7585830 |
Method for the alkoxylation of alkyl and/or alkenyl polyglycosides
A process for the production of alkoxylated alkyl and/or alkenyl polyglycosides including reacting alkylene oxides with alkyl and alkenyl polyglycosides corresponding to formula (I): R 1 O-[G] p ...
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7582311 |
Injection vehicle for polymer-based formulations
The invention provides injection vehicles suitable for administering particulate suspensions, such as polymer-based formulations, as well as associated pharmaceutical formulations, articles of...
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RE40786 |
Vaccines against intracellular pathogens using antigens encapsulated within biodegradable-biocompatible microspheres
This invention relates to parenteral and mucosal vaccines against diseases caused by intercellular pathogens using antigens encapsulated within a biodegradable-biocompatible microspheres(matrix).
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7531192 |
Delivery systems for functional ingredients
The present invention provides oral delivery systems for functional ingredients, such as drugs, nutritional supplements, botanicals, and vitamins. The delivery systems comprise an ingestible matrix...
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7531191 |
Stimuli-responsive systems for controlled drug delivery
A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is...
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7527807 |
Compositions and methods for increasing the oral absorption of antimicrobials
The present invention provides compositions and methods for increasing absorption of antibacterial agents, particularly third generation cephalosporin antibacterial agents, in oral dosage solid...
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7524514 |
Biomimetic composition reinforced by a polyelectrolytic complex of hyaluronic acid and chitosan
The present invention relates to a three dimensional, malleable cell culture composition and method of forming the same comprising hyaluronic acid, chitosan and a polyelectrolytic complex of...
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7521072 |
Dietary fiber delivery system
A delivery system and method for delivering soluble dietary fibers in a chewable tablet form which is palatable and demonstrates a high degree of consumer acceptability.
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7510725 |
Process for producing a dura substitute
The invention relates to dura substitutes to be used as prostheses for dural defects in the field of neurosurgery and processes for producing the same. The present invention provides artificial...
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7504386 |
Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives
New biomaterials essentially constituted by esterified derivatives of hyaluronic acid or by cross-linked derivatives of hyaluronic acid for use in the surgical sector, particularly for use in the...
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7494669 |
Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
In-situ gelation of a pectic substance. Composition, method of preparation, and method of use of a pectin in-situ gelling formulation for the delivery and sustained release of a physiologically...
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7485623 |
Reduction of breast density with 4-hydroxy tamoxifen
A method of treatment comprises administering 4-hydroxy tamoxifen percutaneously to a patient having dense breast tissue. The 4-hydroxy tamoxifen may be formulated in a hydroalcoholic gel or an...
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7485617 |
Osteoinductive materials
The present invention concerns improved osteoinductive materials comprising matrix materials and morphogenetic roteins, wherein depending on the subject matter the proteins may be dimeric or...
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7446088 |
Compositions comprising low-DP polymerized surfactants and methods of use thereof
Provided are low-irritation personal care compositions comprising a low-DP polymerized surfactants. Also provided are methods of making and using such compositions.
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7439044 |
High viscosity xanthan polymer preparations
Increasing the molecular length of xanthan polymer makes a higher viscosity xanthan composition. Xanthan with higher specific viscosity characteristics provides more viscosity at equivalent...
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7431943 |
Controlled release and taste masking oral pharmaceutical compositions
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic,...
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7417021 |
Biologically active conjugate of a biopolymer and therapeutic agent
A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a...
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7410947 |
Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with...
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7407671 |
Temperature controlled solute delivery system
A system for delivering solute to a target location within a mammalian body, the system including a medical device, a thermosensitive cellulose gel structure over the medical device, and a...
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7399739 |
Vertebral augmentation composition and method
A flowable vertebral augmentation composition for the treatment and repair of a vertebral body defect, e.g., an osteoporotic condition, contains biocompatible, optionally osteoconductive, support...
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7399483 |
Carrier with solid fibrinogen and solid thrombin
The present invention relates to a solid composition useful for tissue gluing, tissue sealing and haemostasis consisting essentially of a) a carrier which has at least one of the following physical...
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7381227 |
Fabric laundering
Relatively low levels of polysaccharides in combination with small, deformable, water-insoluble particles of a size in the range 0.05-5 microns are capable of giving benefits in a wash liquor in...
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7375096 |
Method of preparing a supramolecular complex containing a therapeutic agent and a multi-dimensional polymer network
A method of preparing a supramolecular complex containing at least one therapeutic agent and a multi-dimensional polymer network is described. A supramolecular complex prepared by a method of the...
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7374775 |
Dura substitute and a process for producing the same
The invention relates to dura substitutes to be used as prostheses for dural defects in the field of neurosurgery and processes for producing the same. The present invention provides artificial...
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7364753 |
Magnesium-containing compositions and methods for enhancing dehydroepiandrosterone levels
Compositions and methods for using the same to restore dehydroepiandrosterone (DHEA) levels in humans are described. The compositions comprise magnesium chloride, a suitable solvent, a gelling...
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7357946 |
Uses for cellulose-containing aggregates
Aggregates of cellulose-containing particles, such as particles of waste paper and optional other vegetation or waste particles are used as a carrier for additives such as insecticides, herbicides,...
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7347988 |
Synthesis, uses and compositions of crystal hydrogels
A method is disclosed for creating hydrogels with ordered crystalline structures that exhibit a characteristic colored opalescence. In addition to the unique optical properties, these materials...
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7338667 |
Pharmaceutical formulation
The present invention concerns an extended release formulation having an accelerating erosion and/or dissolution rate of the surface of the formulation. The formulation comprises a drug having low...
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7338664 |
Color changing matrix as wear indicator
A sustained-release matrix for dental application includes either an anti-microbial agent or a colorant that is released from the matrix when the matrix contacts water. The preferred matrices...
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7335627 |
Polymeric alkylpolyglycoside carboxylates
The products of the invention are polymers of carboxylated alkylpolyglycosides. The products are very mild surfactants that are useful in personal care applications.
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7332566 |
Biocompatible crosslinked polymers with visualization agents
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having...
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7326425 |
Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release
A formulation containing a biologically active compound having a structure with hydrogen bonding sites blended with a first polymer having a structure with complementary hydrogen bonding sites and...
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7285266 |
Cell-polymer fiber compositions and uses thereof
The present invention relates to compositions comprising complexes of human cells and polymer fibers and methods of their use for therapeutic purposes. Methods of making such compositions are also...
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7285157 |
Air filter
An air-filter for a circulating and/or recirculating air system using a filter medium containing a microbiologically effective amount of a polymeric biguanide or salt thereof. Also claimed is a...
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7276256 |
Cosmetic or healing gel for application to the human skin
A gel formed from an intimate mixture of polyvinyl alcohol, an alkaline or alkaline earth metal borate, water and an alginate and/or a carrageenan, having cryogenic characteristics, substances with...
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7270834 |
Pharmaceutical composition comprising dimethylsulfoxide and ozone
A pharmaceutical composition to be externally applied as a topical preparation for treating several diseases, the composition comprising dimethylsulfoxide (DMSO) and ozone. A method for obtaining...
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7267828 |
Light stabilized antimicrobial materials
Methods of enhancing the photostabilizing of silver in medical materials are described. More particularly, the methods increase the photostabilization of silver in certain materials comprising...
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7262157 |
Cationic cassia derivatives and applications therefor
This invention relates to cationically derivatized polycalactomannans obtained from cassia tora and cassia obtusifolia and to their use in personal care, household care, and institutional care...
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7235259 |
Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors
A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer.
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7229644 |
Pharmaceutical formulations of modafinil
The present invention is related to compositions of modafinil, including compositions of modafinil and one or more diluents, disintegrants, binders and lubricants, and the processes for their...
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7229642 |
Amino acid modulated extended release dosage form
Disclosed herein is a oral extended release dosage form comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an...
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7214371 |
Tissue engineered biografts for repair of damaged myocardium
The invention is directed to tissue-engineered biografts, methods for preparing the biografts of the invention, and methods for repairing a damaged myocardium in a mammal. The methods of the...
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7208480 |
Polysaccharide based gel
A fluid gel obtainable by a process which comprises subjecting a solution comprising a mixture of xanthan and one or more non-gelling polysaccharides selected from galactomannans or glucomannans in...
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7202233 |
Alprazolam inclusion complexes and pharmaceutical compositions thereof
A pharmaceutical composition an inclusion complex and methods for treating patients and preparing said complex disclosed for transmucosal delivery comprising an inclusion complex of (a) alprazolam...
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7202230 |
Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity
The present invention describes the use of polysaccharide derivatives for the preparation of biocompatible and biodegradable biomaterials with absorbent properties for body fluids and physical...
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7201923 |
Encapsulation of sensitive liquid components into a matrix to obtain discrete shelf-stable particles
A liquid encapsulant component which contains an active, sensitive encapsulant, such as a live microorganism or an enzyme dissolved or dispersed in a liquid plasticizer is admixed with a...
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7189414 |
Controlled release oral drug delivery system
The invention relates to synchronous drug delivery composition comprising a polymeric matrix which comprises hydrogel blended with a hydrophobic polymer, so as to form an erodible matrix, a drug,...
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